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The map label for this gene is ubiG [H]

Identifier: 114799822

GI number: 114799822

Start: 616929

End: 617705

Strand: Reverse

Name: ubiG [H]

Synonym: HNE_0617

Alternate gene names: 114799822

Gene position: 617705-616929 (Counterclockwise)

Preceding gene: 114800367

Following gene: 114798906

Centisome position: 16.67

GC content: 65.25

Gene sequence:

>777_bases
ATGGCGAGAACAATTGACGCGTCTGACGCAGCGCCCGTGACGCCGAGCATCGACCCGGCCGAAGTGGCCAAGTTTTCCGC
CATGGCGGCCGACTGGTGGAACCCTGACGGCAAGTTCAAGCCGCTCCACCGGTTCAACCCCACACGGTTGAAATTCATCC
GCGAGACGGCCGAGCGCCATTTCGGCCTGCCTCTGGGGGAGTTGCGCCCGCTCAAGGGCCTGCGTCTGCTCGACATTGGC
TGCGGCGGGGGCCTTGTCTCCGAGCCGATGGCGCGCCTGGGCGCGGCGGTCACGGGGGTGGACGCCTCCGAAGCCAATAT
CAAGACCGCCCTCACCCATGCCAGCCAGCAGGGCCTGAACATCGACTATCGCGCCGGCACGGCCGAGGGTCTGCTGGCGA
GCGGCGAGGCGGCGTTCGACATCGTGCTGAATATGGAAGTGGTCGAGCATGTGGCTGACCCGGCGCAGTTCCTGATGGAC
ACTGCCCAGCTGGTGAAGCCCGGCGGGCTGATGATCGTGGCAACGCTCAACAAGACTGCCAAGGCGCTGGCCACCGCCGT
GATCGGGGCCGAGTACATCTTGCGCTGGTTGCCGCCAGGCACGCATGACTGGTCGAAATTCCTGGCGCCGGAAGATGTGA
CCCGGCCGCTGGAAAGCGCGGGGATGGAAACGGACACGCCCATCGGCGTCAGCTTTCATCCACTCAGCGGGGCGTGGAAA
CTTTCGGAGGATACCAGCGTGAACTATATGGTTGTTGCCCGGAGGCCCGCCGCATGA

Upstream 100 bases:

>100_bases
CGCCATTTCGCCCCAAATACCTTCTGGCCCCTTGAGGCCCGCTCATTTATCGGCCCCTCTAGAAGAAAGTCGGGCCGGGA
TCAAACAGGATTGCTAAACA

Downstream 100 bases:

>100_bases
TTGCCCTTCCCTCGCCCGCCACCGTGCATGCTTTCTGGTTTGGCGGGTCAGCCGCATCTCCCGAAGTGCTCAAGACCCAT
GCACCGCTCTGGTTCAATGG

Product: ubiquinone biosynthesis O-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MARTIDASDAAPVTPSIDPAEVAKFSAMAADWWNPDGKFKPLHRFNPTRLKFIRETAERHFGLPLGELRPLKGLRLLDIG
CGGGLVSEPMARLGAAVTGVDASEANIKTALTHASQQGLNIDYRAGTAEGLLASGEAAFDIVLNMEVVEHVADPAQFLMD
TAQLVKPGGLMIVATLNKTAKALATAVIGAEYILRWLPPGTHDWSKFLAPEDVTRPLESAGMETDTPIGVSFHPLSGAWK
LSEDTSVNYMVVARRPAA

Sequences:

>Translated_258_residues
MARTIDASDAAPVTPSIDPAEVAKFSAMAADWWNPDGKFKPLHRFNPTRLKFIRETAERHFGLPLGELRPLKGLRLLDIG
CGGGLVSEPMARLGAAVTGVDASEANIKTALTHASQQGLNIDYRAGTAEGLLASGEAAFDIVLNMEVVEHVADPAQFLMD
TAQLVKPGGLMIVATLNKTAKALATAVIGAEYILRWLPPGTHDWSKFLAPEDVTRPLESAGMETDTPIGVSFHPLSGAWK
LSEDTSVNYMVVARRPAA
>Mature_257_residues
ARTIDASDAAPVTPSIDPAEVAKFSAMAADWWNPDGKFKPLHRFNPTRLKFIRETAERHFGLPLGELRPLKGLRLLDIGC
GGGLVSEPMARLGAAVTGVDASEANIKTALTHASQQGLNIDYRAGTAEGLLASGEAAFDIVLNMEVVEHVADPAQFLMDT
AQLVKPGGLMIVATLNKTAKALATAVIGAEYILRWLPPGTHDWSKFLAPEDVTRPLESAGMETDTPIGVSFHPLSGAWKL
SEDTSVNYMVVARRPAA

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=244, Percent_Identity=40.5737704918033, Blast_Score=199, Evalue=2e-51,
Organism=Escherichia coli, GI1788564, Length=244, Percent_Identity=41.3934426229508, Blast_Score=201, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI115533050, Length=246, Percent_Identity=34.1463414634146, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324476, Length=230, Percent_Identity=27.8260869565217, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281365311, Length=262, Percent_Identity=30.9160305343511, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24585589, Length=225, Percent_Identity=32.8888888888889, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 27566; Mature: 27435

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTIDASDAAPVTPSIDPAEVAKFSAMAADWWNPDGKFKPLHRFNPTRLKFIRETAERH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHH
FGLPLGELRPLKGLRLLDIGCGGGLVSEPMARLGAAVTGVDASEANIKTALTHASQQGLN
CCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHCCCE
IDYRAGTAEGLLASGEAAFDIVLNMEVVEHVADPAQFLMDTAQLVKPGGLMIVATLNKTA
EEECCCCCCCEEECCCCEEEEEEEHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCHHH
KALATAVIGAEYILRWLPPGTHDWSKFLAPEDVTRPLESAGMETDTPIGVSFHPLSGAWK
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCEE
LSEDTSVNYMVVARRPAA
ECCCCCCEEEEEEECCCC
>Mature Secondary Structure 
ARTIDASDAAPVTPSIDPAEVAKFSAMAADWWNPDGKFKPLHRFNPTRLKFIRETAERH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHHH
FGLPLGELRPLKGLRLLDIGCGGGLVSEPMARLGAAVTGVDASEANIKTALTHASQQGLN
CCCCHHHCCCCCCCEEEEECCCCCHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHCCCE
IDYRAGTAEGLLASGEAAFDIVLNMEVVEHVADPAQFLMDTAQLVKPGGLMIVATLNKTA
EEECCCCCCCEEECCCCEEEEEEEHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCHHH
KALATAVIGAEYILRWLPPGTHDWSKFLAPEDVTRPLESAGMETDTPIGVSFHPLSGAWK
HHHHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCEE
LSEDTSVNYMVVARRPAA
ECCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA