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The map label for this gene is schC [H]

Identifier: 114799635

GI number: 114799635

Start: 2304653

End: 2306332

Strand: Reverse

Name: schC [H]

Synonym: HNE_2208

Alternate gene names: 114799635

Gene position: 2306332-2304653 (Counterclockwise)

Preceding gene: 114800415

Following gene: 114798191

Centisome position: 62.25

GC content: 62.08

Gene sequence:

>1680_bases
ATGAACACAATCGAAACGCCAGTGCTGATCATGGGAGGTGGGCCTGCCGGCCTGGCGCTCGCGGTGGATCTCGGATGGCG
CGGCGTTCCCTGCGTTCTGATTGAGCAGGAGGGACCGGAAGCCCGGCGAAACCATCCCCGGATGGATAATGTCGGCATCC
GCTCCATGGAGTTTGCGCGCCGCTGGGGCATCGTCAAACAGGTCGAGCAGGCAGGCTTTCCGCGCGATTTGCCACTGAGC
ATCGCCTATACGACCGGCATCCTCGGCCCCGAGCTTGCCCGCGATATCGGCCCGACCCTGCAGGAAGCGCCTGTGCCGCC
GTTCAGCCCGCAGAAGCATGAACTCTGCCCACAGAACTTTTTCGATCCGGTTATGCAGGAAGCGGCCCAATCCTATCGGG
GAAATCGCCTATATTATCACCACAAACTGACAGCATTTCAGGATGAAGGGCACCAGGTTCTGGCGACGGTCGAGCCAACC
GATGGCGGAACGCCGCTTCTTGTCAGGGCGCAATATCTGATGGCGTGCGACGGCGCAGGGAGTTCTGTCGCGGCCGCCCT
TGGGCAATCGCCCGTCATGGACCGACTTCTCAGCTGTAGCACGAACATCTTTATACGGAGCCCCGAGCTGACCGCGCGGA
CGGGAGGCTCGCGCGCCTATCGCTACATCCTTGTGGGCGTCGACGGCGTGTGGGGAAGTTTTGTCAACATTGATGGACGG
GATGTGTGGCGGCTTCAGTTGCTGGGCAGTGACACCTGGCCAGCCTGGAGCGACGACGATATTCATGCATTCGTCCGCAG
GGGGCTTGGCGGCGAGGTGGCGTATGAACTTCTTTCCTGGGTTCCCTGGGCACGGCGGGAGCGCGTTGCGGATCGGTTCA
GGGTTGGCCGTTGCTTCCTGGTGGGCGACTCGGCGCATCAGATGTCCCCCACTGGCGGCTACGGCATGAACACGGGCATA
GCGGAAGCTGTGGATCTTTCCTGGAAAATTGCGGCGGTCCTTGATGGCTGGGGTGGGCCTGCCTTGCTTGACAGTTACGA
AGCCGAACGCCGGCCGGTTGCCGCCCGCAATGTGAAGCAGGGGTCGGAAAACCTCTCAGCGATGCGCAGCGCGCCGTCTG
AGCCGCGTTTGCTGGAGCCGGGGGAGGTGGGCAATATCGCCCGTGCCAAGGTCGGCCAATGGGTGCGCGCCGCAATGCAG
AGAGAATGGCGCTCATACGGAATTCATCTGGGGGCGATCTATCGCGGATCTCCGATAACGGCTGCCGAGGAAGCAGACTG
TCCCGAACAGGATGTCGCTCAGTTCGCGCAGCGTGCGTGTGTAGGCGGCCGCGCGCCGCATATCTGGCTGGCAGAGGGGC
AGTCGACGCTGGACCTGTTCGGGCGGGGCTTTGTGCTTCTCGATTTCAGTGGTCATTCTGCGGAACCAGTGGCGCCCCTG
ATTAAGGCGGCAGAAATAGCAGGGGTGCCGCTGGCCTATCAGGCGATCACCAATGACGAGGCCGCACGGCTTTTTGAAAC
ATCTTATGTGCTGGTACGTCCGGACGGCCACATCGCCTGGCGGAGTGATGCGCCGCCTGAAAATCCTGGGAAGCTGATTG
ACCGCGTGCGGGGCGTTGCATCGGGGGCCACTGGGGACCGCCCCGTTCATCTGGAAACGGCAAAAACCACTACGACTTAA

Upstream 100 bases:

>100_bases
TTAAAGCATGGTTTCCGCGACTATCGCGTTGACAAATGCATGCATTATGACTTCTTTGCGCGAGTTTTCAGGCAGATGCG
CGTAAAAGAGGGGCCGGCTC

Downstream 100 bases:

>100_bases
TCCCGGTTAGAAAAAAAGGAACGGATCGTCATGGATCACTCACACGAAGCAAGCGGCCCGGATCTTCCTGACTGGGTCAG
TCAGCGGCTGGTTTCGCCCA

Product: hypothetical protein

Products: H2O; 3-(2,3-dihydroxyphenyl)propionate; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MNTIETPVLIMGGGPAGLALAVDLGWRGVPCVLIEQEGPEARRNHPRMDNVGIRSMEFARRWGIVKQVEQAGFPRDLPLS
IAYTTGILGPELARDIGPTLQEAPVPPFSPQKHELCPQNFFDPVMQEAAQSYRGNRLYYHHKLTAFQDEGHQVLATVEPT
DGGTPLLVRAQYLMACDGAGSSVAAALGQSPVMDRLLSCSTNIFIRSPELTARTGGSRAYRYILVGVDGVWGSFVNIDGR
DVWRLQLLGSDTWPAWSDDDIHAFVRRGLGGEVAYELLSWVPWARRERVADRFRVGRCFLVGDSAHQMSPTGGYGMNTGI
AEAVDLSWKIAAVLDGWGGPALLDSYEAERRPVAARNVKQGSENLSAMRSAPSEPRLLEPGEVGNIARAKVGQWVRAAMQ
REWRSYGIHLGAIYRGSPITAAEEADCPEQDVAQFAQRACVGGRAPHIWLAEGQSTLDLFGRGFVLLDFSGHSAEPVAPL
IKAAEIAGVPLAYQAITNDEAARLFETSYVLVRPDGHIAWRSDAPPENPGKLIDRVRGVASGATGDRPVHLETAKTTTT

Sequences:

>Translated_559_residues
MNTIETPVLIMGGGPAGLALAVDLGWRGVPCVLIEQEGPEARRNHPRMDNVGIRSMEFARRWGIVKQVEQAGFPRDLPLS
IAYTTGILGPELARDIGPTLQEAPVPPFSPQKHELCPQNFFDPVMQEAAQSYRGNRLYYHHKLTAFQDEGHQVLATVEPT
DGGTPLLVRAQYLMACDGAGSSVAAALGQSPVMDRLLSCSTNIFIRSPELTARTGGSRAYRYILVGVDGVWGSFVNIDGR
DVWRLQLLGSDTWPAWSDDDIHAFVRRGLGGEVAYELLSWVPWARRERVADRFRVGRCFLVGDSAHQMSPTGGYGMNTGI
AEAVDLSWKIAAVLDGWGGPALLDSYEAERRPVAARNVKQGSENLSAMRSAPSEPRLLEPGEVGNIARAKVGQWVRAAMQ
REWRSYGIHLGAIYRGSPITAAEEADCPEQDVAQFAQRACVGGRAPHIWLAEGQSTLDLFGRGFVLLDFSGHSAEPVAPL
IKAAEIAGVPLAYQAITNDEAARLFETSYVLVRPDGHIAWRSDAPPENPGKLIDRVRGVASGATGDRPVHLETAKTTTT
>Mature_559_residues
MNTIETPVLIMGGGPAGLALAVDLGWRGVPCVLIEQEGPEARRNHPRMDNVGIRSMEFARRWGIVKQVEQAGFPRDLPLS
IAYTTGILGPELARDIGPTLQEAPVPPFSPQKHELCPQNFFDPVMQEAAQSYRGNRLYYHHKLTAFQDEGHQVLATVEPT
DGGTPLLVRAQYLMACDGAGSSVAAALGQSPVMDRLLSCSTNIFIRSPELTARTGGSRAYRYILVGVDGVWGSFVNIDGR
DVWRLQLLGSDTWPAWSDDDIHAFVRRGLGGEVAYELLSWVPWARRERVADRFRVGRCFLVGDSAHQMSPTGGYGMNTGI
AEAVDLSWKIAAVLDGWGGPALLDSYEAERRPVAARNVKQGSENLSAMRSAPSEPRLLEPGEVGNIARAKVGQWVRAAMQ
REWRSYGIHLGAIYRGSPITAAEEADCPEQDVAQFAQRACVGGRAPHIWLAEGQSTLDLFGRGFVLLDFSGHSAEPVAPL
IKAAEIAGVPLAYQAITNDEAARLFETSYVLVRPDGHIAWRSDAPPENPGKLIDRVRGVASGATGDRPVHLETAKTTTT

Specific function: Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces halstedii [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=354, Percent_Identity=26.271186440678, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.- [C]

Molecular weight: Translated: 60758; Mature: 60758

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIETPVLIMGGGPAGLALAVDLGWRGVPCVLIEQEGPEARRNHPRMDNVGIRSMEFAR
CCCCCCCEEEECCCCCCEEEEEECCCCCCCEEEEECCCCHHHHCCCCCCCCCCHHHHHHH
RWGIVKQVEQAGFPRDLPLSIAYTTGILGPELARDIGPTLQEAPVPPFSPQKHELCPQNF
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHH
FDPVMQEAAQSYRGNRLYYHHKLTAFQDEGHQVLATVEPTDGGTPLLVRAQYLMACDGAG
HHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEEEEEEEEEECCCC
SSVAAALGQSPVMDRLLSCSTNIFIRSPELTARTGGSRAYRYILVGVDGVWGSFVNIDGR
CHHHHHHCCCHHHHHHHHCCCCEEEECCCCEECCCCCCEEEEEEEEECCCCCCEEECCCC
DVWRLQLLGSDTWPAWSDDDIHAFVRRGLGGEVAYELLSWVPWARRERVADRFRVGRCFL
CEEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEE
VGDSAHQMSPTGGYGMNTGIAEAVDLSWKIAAVLDGWGGPALLDSYEAERRPVAARNVKQ
EECCHHCCCCCCCCCCCCCCHHHHCCCEEEEEEEECCCCCHHHHCCHHHCCCCHHHHHHC
GSENLSAMRSAPSEPRLLEPGEVGNIARAKVGQWVRAAMQREWRSYGIHLGAIYRGSPIT
CHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
AAEEADCPEQDVAQFAQRACVGGRAPHIWLAEGQSTLDLFGRGFVLLDFSGHSAEPVAPL
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCCEEEEEECCCCCCCHHHH
IKAAEIAGVPLAYQAITNDEAARLFETSYVLVRPDGHIAWRSDAPPENPGKLIDRVRGVA
HHHHHHCCCCEEEEECCCCHHHHEEECEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHH
SGATGDRPVHLETAKTTTT
CCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MNTIETPVLIMGGGPAGLALAVDLGWRGVPCVLIEQEGPEARRNHPRMDNVGIRSMEFAR
CCCCCCCEEEECCCCCCEEEEEECCCCCCCEEEEECCCCHHHHCCCCCCCCCCHHHHHHH
RWGIVKQVEQAGFPRDLPLSIAYTTGILGPELARDIGPTLQEAPVPPFSPQKHELCPQNF
HHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHH
FDPVMQEAAQSYRGNRLYYHHKLTAFQDEGHQVLATVEPTDGGTPLLVRAQYLMACDGAG
HHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEEEEEEEEEECCCC
SSVAAALGQSPVMDRLLSCSTNIFIRSPELTARTGGSRAYRYILVGVDGVWGSFVNIDGR
CHHHHHHCCCHHHHHHHHCCCCEEEECCCCEECCCCCCEEEEEEEEECCCCCCEEECCCC
DVWRLQLLGSDTWPAWSDDDIHAFVRRGLGGEVAYELLSWVPWARRERVADRFRVGRCFL
CEEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEE
VGDSAHQMSPTGGYGMNTGIAEAVDLSWKIAAVLDGWGGPALLDSYEAERRPVAARNVKQ
EECCHHCCCCCCCCCCCCCCHHHHCCCEEEEEEEECCCCCHHHHCCHHHCCCCHHHHHHC
GSENLSAMRSAPSEPRLLEPGEVGNIARAKVGQWVRAAMQREWRSYGIHLGAIYRGSPIT
CHHHHHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCC
AAEEADCPEQDVAQFAQRACVGGRAPHIWLAEGQSTLDLFGRGFVLLDFSGHSAEPVAPL
CCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCCEEEEEECCCCCCCHHHH
IKAAEIAGVPLAYQAITNDEAARLFETSYVLVRPDGHIAWRSDAPPENPGKLIDRVRGVA
HHHHHHCCCCEEEEECCCCHHHHEEECEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHH
SGATGDRPVHLETAKTTTT
CCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-(3-hydroxyphenyl)propionate; NADH; O2 [C]

Specific reaction: 3-(3-hydroxyphenyl)propionate + NADH + O2 = H2O + 3-(2,3-dihydroxyphenyl)propionate + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8253693; 8344517 [H]