BacMap

Definition	Hyphomonas neptunium ATCC 15444 chromosome, complete genome.
Accession	NC_008358
Length	3,705,021

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The map label for this gene is fadB1 [H]

Identifier: 114799523

GI number: 114799523

Start: 563750

End: 564532

Strand: Reverse

Name: fadB1 [H]

Synonym: HNE_0566

Alternate gene names: 114799523

Gene position: 564532-563750 (Counterclockwise)

Preceding gene: 114799092

Following gene: 114800507

Centisome position: 15.24

GC content: 63.09

Gene sequence:

>783_bases
ATGGCCTACAATACCCTCATCACCGAAGTGAACGCAGAAGATGGTTACGCGCTCATCCAGATGAACCGCGCAGAGAGCCT
CAACGCCCTCAGCGAGGAAATGATGACGGAGCTGACCCAGGCAATCGACCGGTTTGAAGCGGACGACGCCATCCTCTGCA
TCATCCTGACGGGGACCAAGCGCGCCTTCTCCGGCGGCGCCGATGTCCGCGAGATCCAGTCAAAGACCTTCCCGCAATCC
TATTATGAGGATTTCATCACCCGGAACTGGGAGCGCGCGGCGCGTGCCCGCAAGCCCATCATCGCGGCCGTGGGCGGCTA
TGCCATCGGCGGCGGGTGTGAACTGGCCATGATGTGCGACATCATCCTGGCCGCCGACAATGCCCGCTTCGGTCAGCCGG
AAATCCGCCTCGGCGTGATGCCGGGCGCCGGCGCCACCCAGCGCCTGACCCGCGCTGTGGGCAAGTCAAAGGCGATGGAG
CTGTGCCTCACCGGGCGCATGATGGAGGCCGAGGAGGCTGAACGCTGCGGCCTGGTGGCCCGGATCGTCCCGGCCGATGA
TCTGCTCAGCGAAGCCAAATCCCTGGCCGCCACCATTGCCGCCATGCCCCGCGCTGCTGCGATGATGACAAAAGAGGCGA
TCAAGGCCGCCTTCGAAACCCCGCTTTCACAGGGGATTCAGTTCGAACGCCGCCTGTTCCAGTCGCTTTTCGCCACCGAC
GATCAGAAAGAAGGCATGAAAGCCTATGTGGAGAAGCGCTCGGCCCATTTCCGGGATCGCTGA

Upstream 100 bases:

>100_bases
CCAGCCCCTCTGATGGGCCCGAACGACGCGAGCCCGCAGCGCCCACCCCGACCCCATACCCCACCGGCGGCCAGAGACCG
CCCCCCCTCAAGGACCCGTC

Downstream 100 bases:

>100_bases
CCGGCGCAGGCGAAAAGGCTGCTTTTCCGTCACGATGACGGTTGACGCCCGAGAGCCGTTTATGTATCTCCGCGCCTTCT
GCCCGAGGGACATCCCGCCG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAYNTLITEVNAEDGYALIQMNRAESLNALSEEMMTELTQAIDRFEADDAILCIILTGTKRAFSGGADVREIQSKTFPQS
YYEDFITRNWERAARARKPIIAAVGGYAIGGGCELAMMCDIILAADNARFGQPEIRLGVMPGAGATQRLTRAVGKSKAME
LCLTGRMMEAEEAERCGLVARIVPADDLLSEAKSLAATIAAMPRAAAMMTKEAIKAAFETPLSQGIQFERRLFQSLFATD
DQKEGMKAYVEKRSAHFRDR

Sequences:

>Translated_260_residues
MAYNTLITEVNAEDGYALIQMNRAESLNALSEEMMTELTQAIDRFEADDAILCIILTGTKRAFSGGADVREIQSKTFPQS
YYEDFITRNWERAARARKPIIAAVGGYAIGGGCELAMMCDIILAADNARFGQPEIRLGVMPGAGATQRLTRAVGKSKAME
LCLTGRMMEAEEAERCGLVARIVPADDLLSEAKSLAATIAAMPRAAAMMTKEAIKAAFETPLSQGIQFERRLFQSLFATD
DQKEGMKAYVEKRSAHFRDR
>Mature_259_residues
AYNTLITEVNAEDGYALIQMNRAESLNALSEEMMTELTQAIDRFEADDAILCIILTGTKRAFSGGADVREIQSKTFPQSY
YEDFITRNWERAARARKPIIAAVGGYAIGGGCELAMMCDIILAADNARFGQPEIRLGVMPGAGATQRLTRAVGKSKAMEL
CLTGRMMEAEEAERCGLVARIVPADDLLSEAKSLAATIAAMPRAAAMMTKEAIKAAFETPLSQGIQFERRLFQSLFATDD
QKEGMKAYVEKRSAHFRDR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=243, Percent_Identity=51.8518518518518, Blast_Score=266, Evalue=2e-71,
Organism=Homo sapiens, GI68989263, Length=280, Percent_Identity=28.2142857142857, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI4502327, Length=252, Percent_Identity=32.1428571428571, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI20127408, Length=173, Percent_Identity=34.6820809248555, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI70995211, Length=249, Percent_Identity=29.3172690763052, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI31542718, Length=245, Percent_Identity=27.7551020408163, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI62530384, Length=252, Percent_Identity=26.984126984127, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI260274832, Length=223, Percent_Identity=29.1479820627803, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI45643119, Length=224, Percent_Identity=29.0178571428571, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI260275230, Length=224, Percent_Identity=29.0178571428571, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI295842266, Length=250, Percent_Identity=25.6, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI150378541, Length=250, Percent_Identity=28.8, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4757968, Length=254, Percent_Identity=25.5905511811024, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI49355787, Length=254, Percent_Identity=25.5905511811024, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI213417737, Length=237, Percent_Identity=24.0506329113924, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI157694516, Length=237, Percent_Identity=24.0506329113924, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI25453481, Length=254, Percent_Identity=25.1968503937008, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI51538573, Length=254, Percent_Identity=25.1968503937008, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI221136756, Length=254, Percent_Identity=24.8031496062992, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221136753, Length=254, Percent_Identity=24.8031496062992, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI221307494, Length=254, Percent_Identity=24.8031496062992, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI37594471, Length=179, Percent_Identity=27.9329608938547, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI37594469, Length=179, Percent_Identity=27.9329608938547, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4757966, Length=179, Percent_Identity=29.0502793296089, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI51538581, Length=179, Percent_Identity=29.0502793296089, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI157694520, Length=216, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI261878539, Length=182, Percent_Identity=28.021978021978, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI116235487, Length=220, Percent_Identity=25.4545454545455, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1787659, Length=243, Percent_Identity=40.7407407407407, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI221142681, Length=247, Percent_Identity=31.5789473684211, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787660, Length=252, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788597, Length=251, Percent_Identity=33.0677290836653, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1790281, Length=187, Percent_Identity=35.2941176470588, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082183, Length=246, Percent_Identity=30.0813008130081, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788682, Length=224, Percent_Identity=31.25, Blast_Score=91, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17554946, Length=254, Percent_Identity=47.244094488189, Blast_Score=255, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI25145438, Length=251, Percent_Identity=44.2231075697211, Blast_Score=233, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI17540714, Length=248, Percent_Identity=30.241935483871, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17560910, Length=239, Percent_Identity=30.5439330543933, Blast_Score=110, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17540306, Length=243, Percent_Identity=28.8065843621399, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17558304, Length=168, Percent_Identity=29.7619047619048, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=260, Percent_Identity=28.4615384615385, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI25144276, Length=176, Percent_Identity=31.25, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508951, Length=176, Percent_Identity=31.25, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508953, Length=176, Percent_Identity=31.25, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=269, Percent_Identity=23.7918215613383, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17549921, Length=181, Percent_Identity=30.939226519337, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=220, Percent_Identity=22.2727272727273, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=198, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144157, Length=198, Percent_Identity=25.7575757575758, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141363, Length=184, Percent_Identity=24.4565217391304, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=236, Percent_Identity=27.5423728813559, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20129971, Length=258, Percent_Identity=51.5503875968992, Blast_Score=278, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24653477, Length=258, Percent_Identity=51.5503875968992, Blast_Score=278, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24650670, Length=247, Percent_Identity=32.3886639676113, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=32.156862745098, Blast_Score=114, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21357171, Length=246, Percent_Identity=32.1138211382114, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19922422, Length=254, Percent_Identity=25.9842519685039, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19920382, Length=223, Percent_Identity=30.0448430493274, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24654903, Length=229, Percent_Identity=24.4541484716157, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24583077, Length=179, Percent_Identity=29.608938547486, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583079, Length=179, Percent_Identity=29.608938547486, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583165, Length=246, Percent_Identity=24.390243902439, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19921000, Length=179, Percent_Identity=29.608938547486, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571730, Length=169, Percent_Identity=28.9940828402367, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571729, Length=169, Percent_Identity=28.9940828402367, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28526; Mature: 28395

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYNTLITEVNAEDGYALIQMNRAESLNALSEEMMTELTQAIDRFEADDAILCIILTGTK
CCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCC
RAFSGGADVREIQSKTFPQSYYEDFITRNWERAARARKPIIAAVGGYAIGGGCELAMMCD
HHHCCCCHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCEEEEECCEEECCCCHHHHHHH
IILAADNARFGQPEIRLGVMPGAGATQRLTRAVGKSKAMELCLTGRMMEAEEAERCGLVA
HHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHCHHHHHHCCEEE
RIVPADDLLSEAKSLAATIAAMPRAAAMMTKEAIKAAFETPLSQGIQFERRLFQSLFATD
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
DQKEGMKAYVEKRSAHFRDR
CHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AYNTLITEVNAEDGYALIQMNRAESLNALSEEMMTELTQAIDRFEADDAILCIILTGTK
CCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCC
RAFSGGADVREIQSKTFPQSYYEDFITRNWERAARARKPIIAAVGGYAIGGGCELAMMCD
HHHCCCCHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCEEEEECCEEECCCCHHHHHHH
IILAADNARFGQPEIRLGVMPGAGATQRLTRAVGKSKAMELCLTGRMMEAEEAERCGLVA
HHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHCHHHHHHCCEEE
RIVPADDLLSEAKSLAATIAAMPRAAAMMTKEAIKAAFETPLSQGIQFERRLFQSLFATD
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
DQKEGMKAYVEKRSAHFRDR
CHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]