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The map label for this gene is galE [H]

Identifier: 114799522

GI number: 114799522

Start: 1218768

End: 1219775

Strand: Direct

Name: galE [H]

Synonym: HNE_1200

Alternate gene names: 114799522

Gene position: 1218768-1219775 (Clockwise)

Preceding gene: 114798500

Following gene: 114798437

Centisome position: 32.9

GC content: 62.7

Gene sequence:

>1008_bases
ATGCCGGGAAAAGTGCTTGTATTGGGCGGTGCGGGCTATGTGGGCAGTCATTGCTGCCGGGCGTTTTCCGAAGCAGGCTG
GGATGTCACGGTTTTTGACAACCTCTCCACCGGCTGGCGGGACCTGGTGCGCTGGGGCAAGCTGATCGAAGGCGATCTCA
ACAGCCCCGGTGACATCGAGGCGGCTTTCAGCGCAATCAAGCCGGATGCCGTTGCGCACTTCGCGGCGTCCACGCTGGTC
GGAGAGTCGGTCACGGAACCGGGCAAATACTATCGCAACAACACCTTCACGACGCTCAACGTGCTCGATGCCATGCAGCG
CCACAACACGCGCGCGATCATCTTCTCGTCGACCTGCGCGATTTTCGGTCATGCGCAGACGGAGTTTCTCGCCGAGGACC
ATCCGAAGAACCCGATCAACCCCTATGGCATGTCGAAGCTGATGGTGGAGCAAATGCTCGCCGGCTTCGATCATGCCCAT
GGTATTCGCTCTGCCTGCCTGCGGTATTTCAATGCAGCCGGGGCCGACCGCCAGGCCCTCACAGGTGAACGCCATGCCTG
CGAAACGCACCTGATCCCCTTGGCCCTCAAGGGGGCGTATGATCCAGGCTATTCCTTCACCATCACCGGTACGGATTTCG
ATACGCCCGATGGCACGGCCCTGCGAGACTATATCCATGTCGAGGACCTGGCCGAGGCACACCTCCTTGCCTTGAACGCG
CTCGAACAGGGCGCGCCGTCAAATGCGTTCAATCTCGGCACCGGCCGGGGCACCAGCGTGGCGGAGATCGTCGACGCCGT
TGAGCGCGCAACGGGCCGGCGCTTGCCCCGCAAGATCGGACCGCGCCGCCCTGGCGACGCCGCCCGTCTGATTGCGGCGC
CGGGCAGGGCGAAGGATGTGCTTGGCTGGACGGCAAAACGTTCCGATGTCGATAACATCATCACCTCGGCGCTGGCCTGG
CACCAGAAAGACTGGGCGCAGCACAAGGAAGACAGCCTCCAGGGCTGA

Upstream 100 bases:

>100_bases
TCGCCGGCGCTGACGCGCGGTTAGTTTCTTGCATGTATCTGGTGCGTACCGTTGCCTCTGTTATGCAGGGGCACAGTTCA
TTTGAGTTGAGGGGCCAGAA

Downstream 100 bases:

>100_bases
CAGTGCGATGGAAATCGTATGGGGGCTGAGGAACTGAATTCGTGGAAAAAGTAACCGTCATCATTCCCTGCTACAATGCA
GAAGGCTTTATCGAGACGGC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPGKVLVLGGAGYVGSHCCRAFSEAGWDVTVFDNLSTGWRDLVRWGKLIEGDLNSPGDIEAAFSAIKPDAVAHFAASTLV
GESVTEPGKYYRNNTFTTLNVLDAMQRHNTRAIIFSSTCAIFGHAQTEFLAEDHPKNPINPYGMSKLMVEQMLAGFDHAH
GIRSACLRYFNAAGADRQALTGERHACETHLIPLALKGAYDPGYSFTITGTDFDTPDGTALRDYIHVEDLAEAHLLALNA
LEQGAPSNAFNLGTGRGTSVAEIVDAVERATGRRLPRKIGPRRPGDAARLIAAPGRAKDVLGWTAKRSDVDNIITSALAW
HQKDWAQHKEDSLQG

Sequences:

>Translated_335_residues
MPGKVLVLGGAGYVGSHCCRAFSEAGWDVTVFDNLSTGWRDLVRWGKLIEGDLNSPGDIEAAFSAIKPDAVAHFAASTLV
GESVTEPGKYYRNNTFTTLNVLDAMQRHNTRAIIFSSTCAIFGHAQTEFLAEDHPKNPINPYGMSKLMVEQMLAGFDHAH
GIRSACLRYFNAAGADRQALTGERHACETHLIPLALKGAYDPGYSFTITGTDFDTPDGTALRDYIHVEDLAEAHLLALNA
LEQGAPSNAFNLGTGRGTSVAEIVDAVERATGRRLPRKIGPRRPGDAARLIAAPGRAKDVLGWTAKRSDVDNIITSALAW
HQKDWAQHKEDSLQG
>Mature_334_residues
PGKVLVLGGAGYVGSHCCRAFSEAGWDVTVFDNLSTGWRDLVRWGKLIEGDLNSPGDIEAAFSAIKPDAVAHFAASTLVG
ESVTEPGKYYRNNTFTTLNVLDAMQRHNTRAIIFSSTCAIFGHAQTEFLAEDHPKNPINPYGMSKLMVEQMLAGFDHAHG
IRSACLRYFNAAGADRQALTGERHACETHLIPLALKGAYDPGYSFTITGTDFDTPDGTALRDYIHVEDLAEAHLLALNAL
EQGAPSNAFNLGTGRGTSVAEIVDAVERATGRRLPRKIGPRRPGDAARLIAAPGRAKDVLGWTAKRSDVDNIITSALAWH
QKDWAQHKEDSLQG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=37.2434017595308, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=37.2434017595308, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=37.2434017595308, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI42516563, Length=311, Percent_Identity=26.6881028938907, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI7657641, Length=276, Percent_Identity=25, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI116268111, Length=287, Percent_Identity=25.4355400696864, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=36.2537764350453, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI48994969, Length=367, Percent_Identity=22.3433242506812, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=340, Percent_Identity=34.1176470588235, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=33.6257309941521, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17568069, Length=331, Percent_Identity=25.6797583081571, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115532424, Length=351, Percent_Identity=23.6467236467236, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=322, Percent_Identity=38.1987577639752, Blast_Score=194, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6321437, Length=250, Percent_Identity=26, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=35.4651162790698, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21356223, Length=314, Percent_Identity=25.4777070063694, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36240; Mature: 36109

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGKVLVLGGAGYVGSHCCRAFSEAGWDVTVFDNLSTGWRDLVRWGKLIEGDLNSPGDIE
CCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHH
AAFSAIKPDAVAHFAASTLVGESVTEPGKYYRNNTFTTLNVLDAMQRHNTRAIIFSSTCA
HHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCEEEEEECCHH
IFGHAQTEFLAEDHPKNPINPYGMSKLMVEQMLAGFDHAHGIRSACLRYFNAAGADRQAL
HHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHH
TGERHACETHLIPLALKGAYDPGYSFTITGTDFDTPDGTALRDYIHVEDLAEAHLLALNA
CCCHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEQGAPSNAFNLGTGRGTSVAEIVDAVERATGRRLPRKIGPRRPGDAARLIAAPGRAKDV
HHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCEEEECCCCCHHH
LGWTAKRSDVDNIITSALAWHQKDWAQHKEDSLQG
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PGKVLVLGGAGYVGSHCCRAFSEAGWDVTVFDNLSTGWRDLVRWGKLIEGDLNSPGDIE
CCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHH
AAFSAIKPDAVAHFAASTLVGESVTEPGKYYRNNTFTTLNVLDAMQRHNTRAIIFSSTCA
HHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCEEEEEECCHH
IFGHAQTEFLAEDHPKNPINPYGMSKLMVEQMLAGFDHAHGIRSACLRYFNAAGADRQAL
HHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHH
TGERHACETHLIPLALKGAYDPGYSFTITGTDFDTPDGTALRDYIHVEDLAEAHLLALNA
CCCHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEQGAPSNAFNLGTGRGTSVAEIVDAVERATGRRLPRKIGPRRPGDAARLIAAPGRAKDV
HHCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCEEEECCCCCHHH
LGWTAKRSDVDNIITSALAWHQKDWAQHKEDSLQG
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9236769 [H]