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The map label for this gene is mmgC [H]

Identifier: 114799465

GI number: 114799465

Start: 1105129

End: 1106319

Strand: Direct

Name: mmgC [H]

Synonym: HNE_1099

Alternate gene names: 114799465

Gene position: 1105129-1106319 (Clockwise)

Preceding gene: 114799274

Following gene: 114799131

Centisome position: 29.83

GC content: 58.94

Gene sequence:

>1191_bases
ATGGCTGACACGACATATCTCAGTGAAGAAGACGAACGCCAGATCCTCGATTCGATCCAGAAATGGCTCGAAAAGAAGGT
CGCCCCGGTGGCGATGCAGCTGGAACATGACAATGAATGGCCCGCTGATCTTGTCGCCGACATGACCGAGCTCGGCCTGT
TCGGCGCGCTGATCCATCCAGACTATGGCGGGCTTGGCCTGTCTGCGTCGACCTATACGAAGATCGTTACGATGATCTCG
GAAGAGTGGATGAGCCTTTCGGGCATTTTCAATTCTCACCTGATGATGTCCATCGTTGTGCAGAAGTTTGGCACCGACAA
GCAGAAGGAATACTGGCTTCCGAAGTTTGCCGCGGGCGAGCTGCGCGGCGCGCTGGGCCTGACGGAGCCGGACGCTGGCA
CCGACCTTCAGAGCATCCGCACGGTGGCCAAACGCAAGGGCGACAAATACGTCGTCAACGGAACAAAGACGTGGATTTCC
AACGCCATTGAAGGCCACTGCGTGGCGCTTCTGGTCAAGACAGACCCCGACGCCCAGCCGCGTTACAAGGGCATGTCGAT
GCTCATTGTGCCGAAGATCAACCCGGAAACGCGCGCGCCTTTGCCGGGCGTCAAGAATGGCCGCAAGCTGGAAAAGCTCG
GCTATAAGGGCATCGATTCGGGCGAATTCATATTTGAAGATTATGAGTGCGACGCCGAGCTGTCTCTGGTGGGCGGCAAG
GAGGGCGAGGGCTTCTTCATGGCAACCGGCGGGCTCGAGATTGGCCGGATCAATGTGGCGGCTCGCTCTGTCGGGATTGC
GCGGCGCGCGCTGCGCGAAAGCGTGCAGTATTCCCAGCTTCGCAAGACCATGGGAAAGCCGATCTGTGAGCACCAGGCGA
TCCAGTTGAAGCTCGGTGAAATGGCGGCCAAGACGCGCGCCTCCGAACTGCTCGTTCAGGACGCCGCCGCAGCGTATGAT
CGCGGCGACCGCGTCGATATGGAGGCGGGCATGGCGAAGTATTTTGCTTCGGAAACGGCTGTTGAAGTGGCCACCGAGGC
GATGCGTATCCACGGCGGATATGGATATTCGAAAGAGTACGTCATCGAGCGGCTTTACCGCGACGCGCCGCTGATGTGCA
TCGGCGAGGGCACGAACGAGATGCAGCGTATCATCATTGCCAAGCAGCTCGTGAAGCGTAATCCGGCCTGA

Upstream 100 bases:

>100_bases
TCAAGCGCAACATGCTCATCCCCTCACGCGGCAACGCGGTTGAGGACAAGGTCGGCAATTACTGAATTCAGGCGACCCCA
TCAGGTCAGGAGAGCCCAAC

Downstream 100 bases:

>100_bases
TCAGCCCACAAAAATTAAAGGTATTCCGCATATGAAGCGACTGCTCGAAGGCATCCGTATTCTCTCCGTCGAACAGTACG
GGGCAGGTCCTTATGGCACC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MADTTYLSEEDERQILDSIQKWLEKKVAPVAMQLEHDNEWPADLVADMTELGLFGALIHPDYGGLGLSASTYTKIVTMIS
EEWMSLSGIFNSHLMMSIVVQKFGTDKQKEYWLPKFAAGELRGALGLTEPDAGTDLQSIRTVAKRKGDKYVVNGTKTWIS
NAIEGHCVALLVKTDPDAQPRYKGMSMLIVPKINPETRAPLPGVKNGRKLEKLGYKGIDSGEFIFEDYECDAELSLVGGK
EGEGFFMATGGLEIGRINVAARSVGIARRALRESVQYSQLRKTMGKPICEHQAIQLKLGEMAAKTRASELLVQDAAAAYD
RGDRVDMEAGMAKYFASETAVEVATEAMRIHGGYGYSKEYVIERLYRDAPLMCIGEGTNEMQRIIIAKQLVKRNPA

Sequences:

>Translated_396_residues
MADTTYLSEEDERQILDSIQKWLEKKVAPVAMQLEHDNEWPADLVADMTELGLFGALIHPDYGGLGLSASTYTKIVTMIS
EEWMSLSGIFNSHLMMSIVVQKFGTDKQKEYWLPKFAAGELRGALGLTEPDAGTDLQSIRTVAKRKGDKYVVNGTKTWIS
NAIEGHCVALLVKTDPDAQPRYKGMSMLIVPKINPETRAPLPGVKNGRKLEKLGYKGIDSGEFIFEDYECDAELSLVGGK
EGEGFFMATGGLEIGRINVAARSVGIARRALRESVQYSQLRKTMGKPICEHQAIQLKLGEMAAKTRASELLVQDAAAAYD
RGDRVDMEAGMAKYFASETAVEVATEAMRIHGGYGYSKEYVIERLYRDAPLMCIGEGTNEMQRIIIAKQLVKRNPA
>Mature_395_residues
ADTTYLSEEDERQILDSIQKWLEKKVAPVAMQLEHDNEWPADLVADMTELGLFGALIHPDYGGLGLSASTYTKIVTMISE
EWMSLSGIFNSHLMMSIVVQKFGTDKQKEYWLPKFAAGELRGALGLTEPDAGTDLQSIRTVAKRKGDKYVVNGTKTWISN
AIEGHCVALLVKTDPDAQPRYKGMSMLIVPKINPETRAPLPGVKNGRKLEKLGYKGIDSGEFIFEDYECDAELSLVGGKE
GEGFFMATGGLEIGRINVAARSVGIARRALRESVQYSQLRKTMGKPICEHQAIQLKLGEMAAKTRASELLVQDAAAAYDR
GDRVDMEAGMAKYFASETAVEVATEAMRIHGGYGYSKEYVIERLYRDAPLMCIGEGTNEMQRIIIAKQLVKRNPA

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=385, Percent_Identity=36.1038961038961, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI187960098, Length=391, Percent_Identity=36.5728900255754, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI4557231, Length=391, Percent_Identity=36.5728900255754, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI7656849, Length=386, Percent_Identity=31.3471502590674, Blast_Score=208, Evalue=6e-54,
Organism=Homo sapiens, GI226958412, Length=382, Percent_Identity=30.3664921465969, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=30.8139534883721, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI4501859, Length=383, Percent_Identity=29.7650130548303, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI21361497, Length=382, Percent_Identity=32.7225130890052, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=30.2387267904509, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI76496475, Length=398, Percent_Identity=29.6482412060301, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4557235, Length=398, Percent_Identity=29.6482412060301, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI48976061, Length=403, Percent_Identity=26.5508684863524, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI211971008, Length=403, Percent_Identity=26.5508684863524, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4503943, Length=389, Percent_Identity=24.6786632390745, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI38505218, Length=297, Percent_Identity=28.956228956229, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI7669494, Length=362, Percent_Identity=25.414364640884, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI87081958, Length=388, Percent_Identity=28.6082474226804, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1786223, Length=376, Percent_Identity=26.8617021276596, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87082384, Length=307, Percent_Identity=27.6872964169381, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081702, Length=400, Percent_Identity=24.5, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17533517, Length=388, Percent_Identity=33.7628865979381, Blast_Score=208, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17569725, Length=384, Percent_Identity=32.5520833333333, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17534899, Length=387, Percent_Identity=32.5581395348837, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=32.5581395348837, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17538396, Length=394, Percent_Identity=30.4568527918782, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=383, Percent_Identity=30.0261096605744, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI71985184, Length=389, Percent_Identity=31.6195372750643, Blast_Score=174, Evalue=7e-44,
Organism=Caenorhabditis elegans, GI17506239, Length=384, Percent_Identity=28.3854166666667, Blast_Score=171, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17505929, Length=386, Percent_Identity=30.0518134715026, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17551932, Length=395, Percent_Identity=28.3544303797468, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=335, Percent_Identity=30.1492537313433, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71990804, Length=305, Percent_Identity=29.5081967213115, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17534353, Length=395, Percent_Identity=24.3037974683544, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI32563615, Length=241, Percent_Identity=26.1410788381743, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71982178, Length=280, Percent_Identity=27.5, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17562446, Length=336, Percent_Identity=26.7857142857143, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=250, Percent_Identity=28, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=247, Percent_Identity=29.1497975708502, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86563381, Length=247, Percent_Identity=29.1497975708502, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24660351, Length=394, Percent_Identity=35.0253807106599, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI21356377, Length=385, Percent_Identity=34.5454545454545, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24646207, Length=383, Percent_Identity=33.9425587467363, Blast_Score=202, Evalue=4e-52,
Organism=Drosophila melanogaster, GI21355753, Length=391, Percent_Identity=31.2020460358056, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24666513, Length=390, Percent_Identity=31.7948717948718, Blast_Score=188, Evalue=6e-48,
Organism=Drosophila melanogaster, GI281363737, Length=345, Percent_Identity=32.463768115942, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI19920834, Length=387, Percent_Identity=23.7726098191214, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221473076, Length=319, Percent_Identity=26.0188087774295, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550141, Length=319, Percent_Identity=26.0188087774295, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281365206, Length=373, Percent_Identity=22.7882037533512, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24585193, Length=373, Percent_Identity=22.7882037533512, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24585195, Length=373, Percent_Identity=22.7882037533512, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24585191, Length=373, Percent_Identity=22.7882037533512, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43760; Mature: 43629

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTTYLSEEDERQILDSIQKWLEKKVAPVAMQLEHDNEWPADLVADMTELGLFGALIHP
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEECC
DYGGLGLSASTYTKIVTMISEEWMSLSGIFNSHLMMSIVVQKFGTDKQKEYWLPKFAAGE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHH
LRGALGLTEPDAGTDLQSIRTVAKRKGDKYVVNGTKTWISNAIEGHCVALLVKTDPDAQP
HHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHCCCCEEEEEEEECCCCCCC
RYKGMSMLIVPKINPETRAPLPGVKNGRKLEKLGYKGIDSGEFIFEDYECDAELSLVGGK
CCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEECCCCCCEEEEECCC
EGEGFFMATGGLEIGRINVAARSVGIARRALRESVQYSQLRKTMGKPICEHQAIQLKLGE
CCCEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEHHH
MAAKTRASELLVQDAAAAYDRGDRVDMEAGMAKYFASETAVEVATEAMRIHGGYGYSKEY
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VIERLYRDAPLMCIGEGTNEMQRIIIAKQLVKRNPA
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ADTTYLSEEDERQILDSIQKWLEKKVAPVAMQLEHDNEWPADLVADMTELGLFGALIHP
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEECC
DYGGLGLSASTYTKIVTMISEEWMSLSGIFNSHLMMSIVVQKFGTDKQKEYWLPKFAAGE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCHHH
LRGALGLTEPDAGTDLQSIRTVAKRKGDKYVVNGTKTWISNAIEGHCVALLVKTDPDAQP
HHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHHHHCCCCEEEEEEEECCCCCCC
RYKGMSMLIVPKINPETRAPLPGVKNGRKLEKLGYKGIDSGEFIFEDYECDAELSLVGGK
CCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEECCCCCCEEEEECCC
EGEGFFMATGGLEIGRINVAARSVGIARRALRESVQYSQLRKTMGKPICEHQAIQLKLGE
CCCEEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEHHH
MAAKTRASELLVQDAAAAYDRGDRVDMEAGMAKYFASETAVEVATEAMRIHGGYGYSKEY
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VIERLYRDAPLMCIGEGTNEMQRIIIAKQLVKRNPA
HHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]