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The map label for this gene is lpxA [H]

Identifier: 114799420

GI number: 114799420

Start: 1823540

End: 1824334

Strand: Direct

Name: lpxA [H]

Synonym: HNE_1779

Alternate gene names: 114799420

Gene position: 1823540-1824334 (Clockwise)

Preceding gene: 114798725

Following gene: 114797181

Centisome position: 49.22

GC content: 55.85

Gene sequence:

>795_bases
ATGAGCGTTGAGGTGCACTCCACGGCCGTCGTTGAAAGCGGTGCCATTCTCCATGATGGCGTGCGGATCGGCCCATTCTG
CCATGTGGGAGCCATGGCCGAGTTGGGCGCTGGCACTGAGCTCATTTCGCATGCGTCCGTTGTCGGACATACGAAGGTCG
GCTCCAATTGCCTGCTTTATCCCCATGCCGTCCTCGGGTGTGGTCCGCAGGTTCTGGGAATGCGGGAAACACCCGATTCC
ATGCTTGAGGTCGGCGCTGGCAGCGTCTTCCGTGAATACGCAACAGCCCATACGGGAATACCAAAACATGGAGGGCTGAC
CAAAGTCGGAACCGCCTGCTACATCATGATTGGGGCTCATATCGCTCACGACTGCATAATTGGAAACAACGTGGTGATGG
CAAATAATGTGTCCTTGGCGGGCCATATCACCGTTGGCGACAATGTCTGGTTTGGAGGGTTGGCCGCCGTGCATCAATTC
AGCCGCATTGGCCGGAATGCCTTCATCGGCGGCGGCGCGATTGTCGTTGAGGATGTCATTCCATTCGGGTCGGTGGTGGG
CAACCACGCAAAACTTTCGGGACTCAACATCGTTGGTTTGAAGCGGCGAGGATTTAGCAAATCCGATCTCCACGAAATTC
GGTCAGCTTATAAGGCCGTGTTTGAAGGAAACGGTCTGTTCAAGGATAGGCTGGCTCAGGCGGCCGCGGAATACGCGGGG
AAACCCTTGGCAATGGAACTTATCAATTTCATTCTGGAGGGCAGAGATCGCCCCATTTGCAAACCGGCGGAATGA

Upstream 100 bases:

>100_bases
GCAGTGGATGCGGGAAGTCGCATGGTTGCAAAAACAGGCCAACCCCAAGAAAAGCAATTGACGGGCAATTACCTGTCTCG
AAATGAGGAAAGGCCTCTCG

Downstream 100 bases:

>100_bases
CATGCGCGAGCCTTTGGGTCTCATCGCAGGATTGGGAGAATTGCCGGTCGCAATTGCTGAGAATGCTGTAGCAACGGGGC
AGGGTGTTTATGTCCTGCGT

Product: acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MSVEVHSTAVVESGAILHDGVRIGPFCHVGAMAELGAGTELISHASVVGHTKVGSNCLLYPHAVLGCGPQVLGMRETPDS
MLEVGAGSVFREYATAHTGIPKHGGLTKVGTACYIMIGAHIAHDCIIGNNVVMANNVSLAGHITVGDNVWFGGLAAVHQF
SRIGRNAFIGGGAIVVEDVIPFGSVVGNHAKLSGLNIVGLKRRGFSKSDLHEIRSAYKAVFEGNGLFKDRLAQAAAEYAG
KPLAMELINFILEGRDRPICKPAE

Sequences:

>Translated_264_residues
MSVEVHSTAVVESGAILHDGVRIGPFCHVGAMAELGAGTELISHASVVGHTKVGSNCLLYPHAVLGCGPQVLGMRETPDS
MLEVGAGSVFREYATAHTGIPKHGGLTKVGTACYIMIGAHIAHDCIIGNNVVMANNVSLAGHITVGDNVWFGGLAAVHQF
SRIGRNAFIGGGAIVVEDVIPFGSVVGNHAKLSGLNIVGLKRRGFSKSDLHEIRSAYKAVFEGNGLFKDRLAQAAAEYAG
KPLAMELINFILEGRDRPICKPAE
>Mature_263_residues
SVEVHSTAVVESGAILHDGVRIGPFCHVGAMAELGAGTELISHASVVGHTKVGSNCLLYPHAVLGCGPQVLGMRETPDSM
LEVGAGSVFREYATAHTGIPKHGGLTKVGTACYIMIGAHIAHDCIIGNNVVMANNVSLAGHITVGDNVWFGGLAAVHQFS
RIGRNAFIGGGAIVVEDVIPFGSVVGNHAKLSGLNIVGLKRRGFSKSDLHEIRSAYKAVFEGNGLFKDRLAQAAAEYAGK
PLAMELINFILEGRDRPICKPAE

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=238, Percent_Identity=45.7983193277311, Blast_Score=187, Evalue=7e-49,
Organism=Escherichia coli, GI1786376, Length=174, Percent_Identity=29.3103448275862, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 27612; Mature: 27481

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEVHSTAVVESGAILHDGVRIGPFCHVGAMAELGAGTELISHASVVGHTKVGSNCLLY
CCEEECCCEEEECCCEEECCEEECCEECCCHHHHHCCCHHHHHHHHHHCCCCCCCCEEEC
PHAVLGCGPQVLGMRETPDSMLEVGAGSVFREYATAHTGIPKHGGLTKVGTACYIMIGAH
CHHHHCCCHHHCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHEEEEEHHH
IAHDCIIGNNVVMANNVSLAGHITVGDNVWFGGLAAVHQFSRIGRNAFIGGGAIVVEDVI
HHHHEEECCCEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEECCCEEEEEHHH
PFGSVVGNHAKLSGLNIVGLKRRGFSKSDLHEIRSAYKAVFEGNGLFKDRLAQAAAEYAG
HHHHHHCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
KPLAMELINFILEGRDRPICKPAE
CCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SVEVHSTAVVESGAILHDGVRIGPFCHVGAMAELGAGTELISHASVVGHTKVGSNCLLY
CEEECCCEEEECCCEEECCEEECCEECCCHHHHHCCCHHHHHHHHHHCCCCCCCCEEEC
PHAVLGCGPQVLGMRETPDSMLEVGAGSVFREYATAHTGIPKHGGLTKVGTACYIMIGAH
CHHHHCCCHHHCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHEEEEEHHH
IAHDCIIGNNVVMANNVSLAGHITVGDNVWFGGLAAVHQFSRIGRNAFIGGGAIVVEDVI
HHHHEEECCCEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEECCCEEEEEHHH
PFGSVVGNHAKLSGLNIVGLKRRGFSKSDLHEIRSAYKAVFEGNGLFKDRLAQAAAEYAG
HHHHHHCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
KPLAMELINFILEGRDRPICKPAE
CCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA