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The map label for this gene is yngJ [H]

Identifier: 114799393

GI number: 114799393

Start: 2932806

End: 2934095

Strand: Reverse

Name: yngJ [H]

Synonym: HNE_2770

Alternate gene names: 114799393

Gene position: 2934095-2932806 (Counterclockwise)

Preceding gene: 114799900

Following gene: 114800262

Centisome position: 79.19

GC content: 61.55

Gene sequence:

>1290_bases
ATGCAGTTCGAATTCAGCCCAAAGACGAAAGATTATATCGCGCGTGTCAGCGCATTCATGGACCAGCATGTCTATCCCGC
CGTGCCCGACTACAAGGCCCACCACGAAAAGGACCGCTGGGGCGTCAACCCCGTGCTGGAACGCCTGAAGGAGCGGGCCA
AGGCTGAAGGCCTGTGGAACCTGTTCCTGCCGCCGAGCGAAGATCACGACGAGAGCAGCCATCGCGGCGCCGGACTGACC
AATGCCGAATATGCGCCGCTCTCGGAGATCATGGGCCGTGTGTCGTTTGCGTCTGAAGTGTTCAACTGCTCGGCGCCAGA
TACCGGCAATATGGAAGTGCTTCACCGGTATGGATCGCCGCTGCAAAAGGAGCGCTGGCTCGGGCCGTTGCTGCGCGGTG
AAATCCGCTCGGCCTTCCTGATGACAGAGCCGCTGGTTGCCTCCTCCGACGCCACCAATATCGAGACGACGATCACCCGC
GAGGGCGAGGAATACGTCATCAACGGCCGCAAATGGTGGTCCTCCGGTGTGGGCGATCCGCGCTGCAAGGTCGCCATCGT
GATGGGCAAGACGGACGCGAGCGCCGAGCGCCATCAACAGCAAAGCCAGATCCTCGTGCCGATGGACGCGCCGGGCATCA
AGATACTCCGTATGCTGCCCGTATTCGGGTATGATGACAGCCCGCATGGCCATGCCGAAGTGTTGCTGAAAGATGTTCGC
GTGCCTGTTGCAAACCTGATCCTTGGGGAAGGCCGGGGCTTTGAGATTGCACAAGGCCGTCTCGGGCCAGGGCGTATCCA
TCACTGCATGCGCACCATCGGCGCGGCCGAAGTGGCATTGGAAAAACTTACACGCCGCGTTCTGGCACGGGAAGTTTTCG
GCAAGGCGCTTTCCCAGCAATCCATCTGGGAGCAGAGGATCGGCGAAGCCCGGCTCGACATCGAGATGACGCGCCTGCTA
ACCCTGAAAGCCGCTTACATGATGGACACGGTCGGCAACAAGGGCGCGGCCAACGAGATTGCCATGATCAAGGTGGCTGC
CCCGCGCGCCGCTCTGAAGGTGATTGATGAGGCAATCCAGGCCCATGGCGGAGCAGGCGTGACAGATGATTTTGGCCTGG
CTGAACTTTATGCCGGTATCCGCACGCTCCGCCTTGCAGATGGGCCGGACGAGGTGCACCTGCGCGCGATTGCCCGCAAT
GAGGTGAGAAAGTACCGCGAGGCACCGGCCTATCCCGCCCACCGCCCGGAGGCCGGCATTGCTTGGCCGCCGGTGCAAGA
GAGGGTGTAA

Upstream 100 bases:

>100_bases
GTTGAGACGCTTGCCGCGCGGGCATCCGCAAACATCCGTATTCCGCCCATTCTGCCAGAGGCGCAGGCTTTCCCCGGACA
GATGAGACCGGAGAGAGACG

Downstream 100 bases:

>100_bases
CTAGAAAGGAACGTTCGGGTCGTCCTCGCCCTTGCCGCCGAGCATCAGGCCGGCAAAGTCGAAGACGCGCGGATCATGCA
GATGGCTGGGGCGCACATTG

Product: acyl-CoA dehydrogenase family protein

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MQFEFSPKTKDYIARVSAFMDQHVYPAVPDYKAHHEKDRWGVNPVLERLKERAKAEGLWNLFLPPSEDHDESSHRGAGLT
NAEYAPLSEIMGRVSFASEVFNCSAPDTGNMEVLHRYGSPLQKERWLGPLLRGEIRSAFLMTEPLVASSDATNIETTITR
EGEEYVINGRKWWSSGVGDPRCKVAIVMGKTDASAERHQQQSQILVPMDAPGIKILRMLPVFGYDDSPHGHAEVLLKDVR
VPVANLILGEGRGFEIAQGRLGPGRIHHCMRTIGAAEVALEKLTRRVLAREVFGKALSQQSIWEQRIGEARLDIEMTRLL
TLKAAYMMDTVGNKGAANEIAMIKVAAPRAALKVIDEAIQAHGGAGVTDDFGLAELYAGIRTLRLADGPDEVHLRAIARN
EVRKYREAPAYPAHRPEAGIAWPPVQERV

Sequences:

>Translated_429_residues
MQFEFSPKTKDYIARVSAFMDQHVYPAVPDYKAHHEKDRWGVNPVLERLKERAKAEGLWNLFLPPSEDHDESSHRGAGLT
NAEYAPLSEIMGRVSFASEVFNCSAPDTGNMEVLHRYGSPLQKERWLGPLLRGEIRSAFLMTEPLVASSDATNIETTITR
EGEEYVINGRKWWSSGVGDPRCKVAIVMGKTDASAERHQQQSQILVPMDAPGIKILRMLPVFGYDDSPHGHAEVLLKDVR
VPVANLILGEGRGFEIAQGRLGPGRIHHCMRTIGAAEVALEKLTRRVLAREVFGKALSQQSIWEQRIGEARLDIEMTRLL
TLKAAYMMDTVGNKGAANEIAMIKVAAPRAALKVIDEAIQAHGGAGVTDDFGLAELYAGIRTLRLADGPDEVHLRAIARN
EVRKYREAPAYPAHRPEAGIAWPPVQERV
>Mature_429_residues
MQFEFSPKTKDYIARVSAFMDQHVYPAVPDYKAHHEKDRWGVNPVLERLKERAKAEGLWNLFLPPSEDHDESSHRGAGLT
NAEYAPLSEIMGRVSFASEVFNCSAPDTGNMEVLHRYGSPLQKERWLGPLLRGEIRSAFLMTEPLVASSDATNIETTITR
EGEEYVINGRKWWSSGVGDPRCKVAIVMGKTDASAERHQQQSQILVPMDAPGIKILRMLPVFGYDDSPHGHAEVLLKDVR
VPVANLILGEGRGFEIAQGRLGPGRIHHCMRTIGAAEVALEKLTRRVLAREVFGKALSQQSIWEQRIGEARLDIEMTRLL
TLKAAYMMDTVGNKGAANEIAMIKVAAPRAALKVIDEAIQAHGGAGVTDDFGLAELYAGIRTLRLADGPDEVHLRAIARN
EVRKYREAPAYPAHRPEAGIAWPPVQERV

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=403, Percent_Identity=57.3200992555831, Blast_Score=457, Evalue=1e-129,
Organism=Homo sapiens, GI211971008, Length=400, Percent_Identity=56.75, Blast_Score=456, Evalue=1e-128,
Organism=Homo sapiens, GI48976061, Length=400, Percent_Identity=56.75, Blast_Score=456, Evalue=1e-128,
Organism=Homo sapiens, GI4557231, Length=413, Percent_Identity=25.90799031477, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI187960098, Length=413, Percent_Identity=25.90799031477, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI4557233, Length=332, Percent_Identity=31.3253012048193, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI7656849, Length=289, Percent_Identity=28.0276816608997, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4557235, Length=406, Percent_Identity=28.0788177339901, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI76496475, Length=406, Percent_Identity=28.0788177339901, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI21361497, Length=348, Percent_Identity=27.0114942528736, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI4501859, Length=364, Percent_Identity=25.5494505494505, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI226958414, Length=329, Percent_Identity=24.6200607902736, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226958412, Length=329, Percent_Identity=24.6200607902736, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4501857, Length=311, Percent_Identity=25.4019292604502, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4503943, Length=330, Percent_Identity=22.4242424242424, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87081958, Length=314, Percent_Identity=27.3885350318471, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786223, Length=411, Percent_Identity=23.6009732360097, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562446, Length=367, Percent_Identity=54.7683923705722, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17505929, Length=337, Percent_Identity=26.4094955489614, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17551932, Length=336, Percent_Identity=27.0833333333333, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534899, Length=412, Percent_Identity=25, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71985184, Length=346, Percent_Identity=27.7456647398844, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17533517, Length=401, Percent_Identity=25.6857855361596, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17570075, Length=417, Percent_Identity=22.7817745803357, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=355, Percent_Identity=23.943661971831, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=288, Percent_Identity=27.0833333333333, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17506239, Length=291, Percent_Identity=27.8350515463918, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=286, Percent_Identity=26.2237762237762, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=292, Percent_Identity=23.972602739726, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=292, Percent_Identity=25, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356377, Length=330, Percent_Identity=28.4848484848485, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24646207, Length=291, Percent_Identity=29.8969072164948, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI281363737, Length=327, Percent_Identity=27.217125382263, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24660351, Length=283, Percent_Identity=26.8551236749117, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24666513, Length=295, Percent_Identity=26.7796610169492, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355753, Length=295, Percent_Identity=24.0677966101695, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19920834, Length=329, Percent_Identity=23.4042553191489, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 47589; Mature: 47589

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFEFSPKTKDYIARVSAFMDQHVYPAVPDYKAHHEKDRWGVNPVLERLKERAKAEGLWN
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHCCCEE
LFLPPSEDHDESSHRGAGLTNAEYAPLSEIMGRVSFASEVFNCSAPDTGNMEVLHRYGSP
ECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
LQKERWLGPLLRGEIRSAFLMTEPLVASSDATNIETTITREGEEYVINGRKWWSSGVGDP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEECCHHHHCCCCCCC
RCKVAIVMGKTDASAERHQQQSQILVPMDAPGIKILRMLPVFGYDDSPHGHAEVLLKDVR
CEEEEEEECCCCCHHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHC
VPVANLILGEGRGFEIAQGRLGPGRIHHCMRTIGAAEVALEKLTRRVLAREVFGKALSQQ
CCHHHHEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIWEQRIGEARLDIEMTRLLTLKAAYMMDTVGNKGAANEIAMIKVAAPRAALKVIDEAIQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHH
AHGGAGVTDDFGLAELYAGIRTLRLADGPDEVHLRAIARNEVRKYREAPAYPAHRPEAGI
HCCCCCCCCCCCHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AWPPVQERV
CCCCHHCCC
>Mature Secondary Structure
MQFEFSPKTKDYIARVSAFMDQHVYPAVPDYKAHHEKDRWGVNPVLERLKERAKAEGLWN
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHCCCEE
LFLPPSEDHDESSHRGAGLTNAEYAPLSEIMGRVSFASEVFNCSAPDTGNMEVLHRYGSP
ECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCC
LQKERWLGPLLRGEIRSAFLMTEPLVASSDATNIETTITREGEEYVINGRKWWSSGVGDP
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEECCHHHHCCCCCCC
RCKVAIVMGKTDASAERHQQQSQILVPMDAPGIKILRMLPVFGYDDSPHGHAEVLLKDVR
CEEEEEEECCCCCHHHHHHHHCCEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHC
VPVANLILGEGRGFEIAQGRLGPGRIHHCMRTIGAAEVALEKLTRRVLAREVFGKALSQQ
CCHHHHEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIWEQRIGEARLDIEMTRLLTLKAAYMMDTVGNKGAANEIAMIKVAAPRAALKVIDEAIQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHH
AHGGAGVTDDFGLAELYAGIRTLRLADGPDEVHLRAIARNEVRKYREAPAYPAHRPEAGI
HCCCCCCCCCCCHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AWPPVQERV
CCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]