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The map label for this gene is uppP

Identifier: 114799349

GI number: 114799349

Start: 74864

End: 75721

Strand: Reverse

Name: uppP

Synonym: HNE_0091

Alternate gene names: 114799349

Gene position: 75721-74864 (Counterclockwise)

Preceding gene: 114798674

Following gene: 114799844

Centisome position: 2.04

GC content: 64.34

Gene sequence:

>858_bases
ATGTCGATTCTTCAACTCGTCCTAATCGCGCTCATGCAGGGCATCACGGAATGGCTTCCGATCTCCTCATCGGCGCATGT
GATGCTGGTATCGGATGTTGTCGGTCTGGCCGGGCGCGACGAGCTGCTCATCAATGCCGCTTCCAATGCCGGCACGCTGC
TGGCGATGCTGCTATATTTCCGCAAGGATGTCGCCGCTGCCATAGCGGGCGGCTTTGAGCTGCTGGGCGCCCCGGTGACG
CGCAAGCCGCTGTCTGCCGGCGGGCGCCTGGCGCTGTGCATCCTGGTCGCCACGCCGTTTGCGCTGGCCGGCGCGGTTAT
CTACGAAAACTTCATTCCCGAAAACATCTGGACCGCGCTGCGCAGCGTCTATGCCGTGGCTGCCTCGACCATTGTTTTTG
GCGCGCTGCTCTGGTGGGCCGATGCGCGTGGGGGACAGTCCCGTTCCGAGGGCGACATGACCCTGCGCGATGCATTCCTG
ATCGGTGCCAGCCAGCTGGTTGCGGTGATCATCCCCGGCACCAGCCGGTCGGGCATCACGATGACGGCGGCGCGCGCGCT
GGGCTATGAGCGGGTGGAGGCGGCACGCTTTTCCATGCTGATCGGGGCGCCCATTCTGGCGGCGGTAAGCCTTTATGGCC
TCCTGGGACTGGCAACCACCCCGGCAGACGGCATGGGCGCGAGCCTTACAGACGGGCTGATCGTGGCGGCGCTTGCCTTC
GTTTCAGGCTACGCATCCATCGGCCTCCTGATGGCACTTCTGCGGAAGATGAGCTTCCTGCCCTTCGTGCTCTATCGGTT
CGCCCTGGGAATTGCCCTCTTGGCAACCTCGCCTATCGTGGCCGGCGCGATGGGCTGA

Upstream 100 bases:

>100_bases
TCAGAAATATGCATCTCGATGATATGTATTATTTTGCCTGCTTTTCTCCCCAATACTGCTGTAGCGATCTCTCAACACAT
TGGGGGGTATCGCTAGCGGC

Downstream 100 bases:

>100_bases
TCCTCACGCCTCGCGCGGCTTGTGGAACTCACCATAGGGACGGAAGCGCCACAAGTAGGTGGGCACGATCGCCTCGATTG
ATTCCAGCTGCAGAACGCCC

Product: putative undecaprenol kinase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSILQLVLIALMQGITEWLPISSSAHVMLVSDVVGLAGRDELLINAASNAGTLLAMLLYFRKDVAAAIAGGFELLGAPVT
RKPLSAGGRLALCILVATPFALAGAVIYENFIPENIWTALRSVYAVAASTIVFGALLWWADARGGQSRSEGDMTLRDAFL
IGASQLVAVIIPGTSRSGITMTAARALGYERVEAARFSMLIGAPILAAVSLYGLLGLATTPADGMGASLTDGLIVAALAF
VSGYASIGLLMALLRKMSFLPFVLYRFALGIALLATSPIVAGAMG

Sequences:

>Translated_285_residues
MSILQLVLIALMQGITEWLPISSSAHVMLVSDVVGLAGRDELLINAASNAGTLLAMLLYFRKDVAAAIAGGFELLGAPVT
RKPLSAGGRLALCILVATPFALAGAVIYENFIPENIWTALRSVYAVAASTIVFGALLWWADARGGQSRSEGDMTLRDAFL
IGASQLVAVIIPGTSRSGITMTAARALGYERVEAARFSMLIGAPILAAVSLYGLLGLATTPADGMGASLTDGLIVAALAF
VSGYASIGLLMALLRKMSFLPFVLYRFALGIALLATSPIVAGAMG
>Mature_284_residues
SILQLVLIALMQGITEWLPISSSAHVMLVSDVVGLAGRDELLINAASNAGTLLAMLLYFRKDVAAAIAGGFELLGAPVTR
KPLSAGGRLALCILVATPFALAGAVIYENFIPENIWTALRSVYAVAASTIVFGALLWWADARGGQSRSEGDMTLRDAFLI
GASQLVAVIIPGTSRSGITMTAARALGYERVEAARFSMLIGAPILAAVSLYGLLGLATTPADGMGASLTDGLIVAALAFV
SGYASIGLLMALLRKMSFLPFVLYRFALGIALLATSPIVAGAMG

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=272, Percent_Identity=29.7794117647059, Blast_Score=98, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_HYPNA (Q0C618)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_758825.1
- STRING:   Q0C618
- GeneID:   4288119
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_0091
- NMPDR:   fig|228405.5.peg.89
- TIGR:   HNE_0091
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   SAYICVK
- ProtClustDB:   CLSK777537
- BioCyc:   HNEP81032:HNE_0091-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29505; Mature: 29374

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf42e6a0)-; HASH(0x1045b01c)-; HASH(0x10454834)-; HASH(0x1045ce94)-; HASH(0x1045eefc)-; HASH(0x10456ca8)-; HASH(0x1045d044)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILQLVLIALMQGITEWLPISSSAHVMLVSDVVGLAGRDELLINAASNAGTLLAMLLYF
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCCCEEEECCCCHHHHHHHHHHH
RKDVAAAIAGGFELLGAPVTRKPLSAGGRLALCILVATPFALAGAVIYENFIPENIWTAL
HHHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RSVYAVAASTIVFGALLWWADARGGQSRSEGDMTLRDAFLIGASQLVAVIIPGTSRSGIT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCH
MTAARALGYERVEAARFSMLIGAPILAAVSLYGLLGLATTPADGMGASLTDGLIVAALAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
VSGYASIGLLMALLRKMSFLPFVLYRFALGIALLATSPIVAGAMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCH
>Mature Secondary Structure 
SILQLVLIALMQGITEWLPISSSAHVMLVSDVVGLAGRDELLINAASNAGTLLAMLLYF
HHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCCCEEEECCCCHHHHHHHHHHH
RKDVAAAIAGGFELLGAPVTRKPLSAGGRLALCILVATPFALAGAVIYENFIPENIWTAL
HHHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
RSVYAVAASTIVFGALLWWADARGGQSRSEGDMTLRDAFLIGASQLVAVIIPGTSRSGIT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCH
MTAARALGYERVEAARFSMLIGAPILAAVSLYGLLGLATTPADGMGASLTDGLIVAALAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
VSGYASIGLLMALLRKMSFLPFVLYRFALGIALLATSPIVAGAMG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA