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The map label for this gene is 114799347

Identifier: 114799347

GI number: 114799347

Start: 995032

End: 996513

Strand: Direct

Name: 114799347

Synonym: HNE_0980

Alternate gene names: NA

Gene position: 995032-996513 (Clockwise)

Preceding gene: 114800345

Following gene: 114800084

Centisome position: 26.86

GC content: 59.72

Gene sequence:

>1482_bases
ATGGACCAGGCGGTCAACAAGGCGACGACACGGATTGCCATTCTCGGCGCCGGGATGAGCGGGCTGGGCGCGGCGGCCAA
GCTCAAGGAAGCTGGCTACAGCGTCATCGACATTTTCGAGAAGTCTGGCGGGGTAGGCGGCACCTGGCGGGACAACACCT
ATCCGGGATGCGGATGTGATGTGCCCAGCCATCTTTATTCCTATTCGTTCGAGCTTAATCCGGACTGGGATTACAAATGG
TCGCTCCAGCCGCAGATCCTCAAATATTTCGAGGATTTTGCCGACAAGTATGATGTGCGCCGGCATTGCCGGTTCAACAC
CGAGATTACCGAGTGCCGGTGGGATGACGCGGCCAACAGCTGGACGCTGACCGACCGGGCGGGGAAGACGTATACGGCCG
ATGTGCTGATTTCCGGTCTGGGGCAGCTGAACATTCCGCATACGCCCAACTTCCCCGGCCTCGACACGTTCAAGGGCGGG
GCGTTCCATTCGGCGCGGTGGGACCATTCGGTGGGTCTGAAAGGCAAGACGGTTGCGGTGATCGGAAATGGTCCGAGCGC
GGTGCAGTTTGTGCCGGAGATTCAGAAGGTCGTCGGCAAGATGCTGAGCTTTCAGCGCTCGCCGGCCTGGTGCCGTCCGC
GCGGGCAGCGGGCGTATGACGCCAAAGCGAAGAAATACTTTGCGGGCGCAGACTGGCGGATCAACTGGTATCGGTGGCGC
ATCCGGGCGTTTGCCGATTTCGGCTTTGGCGCGTTCTTGCAGAAGTCTCCGCTGGGGCTGGCCGATTCCATGAAGAAGAT
GTGCCAGAAGCATCTGGAAGATCAGGTGCAGGACCCTGTGCTGCGCGAGAAGCTGACGCCGGATTTCGAGCCGGGGTGCA
AACGTATTCTGATCTCGGATGATTATTATCCCGCGCTGGCCAAGCCGAATGTCGACGTGCTGCGCCAGGGCATCAAGGCG
GTGACGCCGGACGGGGTGATCGGCGAGGACGGGCAGGAATATAAATGTGACGCGATCATCTGGGCGACGGGGTTCCAGTC
GACCGAGTTCCTGACGCCGATGCAGGTGTATGGCCGCAATGGCCTCAGCCTGAACCAGGCCTGGAAGGATGGCGCCGAGG
CGTTCAAGGGGATGGCGGTCTCGGGCTTCCCGAACCTCTTCCTGCTGTATGGACCCAATACCAATCTTGGCCACAACTCC
ATCATCCTGATGGTGGAGCACCAGATCCACTACATGATCCAGTGTATCGACAAGATTGCCGAGAAGGGCGTGGCGGCGAT
TGACGTGACGCCCTCAGCGATGACCGCTTATAACGTGCGTGTACAGAGCGAGATTGCCAAGACGGTCTGGGCGTCGGACT
GCCACAGCTGGTACAAGAACGAGGCCGGCAAGGTGACCAATAACTGGTATGGCAAGACGACCGATTACAAGAAAGAGACG
CGCACGCCGGACTGGACGGATTTTGAGGTGGTGAAGGGCTGA

Upstream 100 bases:

>100_bases
CCCGGCGCCCGTAAGCCCTGCCCCTCGGGCACCGGTTGACGCGCCGGGCAGCACTTAGCAATCCTGACGGAAAGATACCT
ATCAGGGAGGCAAGCGGCTA

Downstream 100 bases:

>100_bases
TCCTTTCGCCAGAAAAGAAAAAGCCCCCTCCGAGGAGGGGGCTTTTTTTGTTACATAGGCTCTGTACGGACGGGGGCGAG
GTCGGGGAAGACCGGCTCGC

Product: putative 4-hydroxyacetophenone monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MDQAVNKATTRIAILGAGMSGLGAAAKLKEAGYSVIDIFEKSGGVGGTWRDNTYPGCGCDVPSHLYSYSFELNPDWDYKW
SLQPQILKYFEDFADKYDVRRHCRFNTEITECRWDDAANSWTLTDRAGKTYTADVLISGLGQLNIPHTPNFPGLDTFKGG
AFHSARWDHSVGLKGKTVAVIGNGPSAVQFVPEIQKVVGKMLSFQRSPAWCRPRGQRAYDAKAKKYFAGADWRINWYRWR
IRAFADFGFGAFLQKSPLGLADSMKKMCQKHLEDQVQDPVLREKLTPDFEPGCKRILISDDYYPALAKPNVDVLRQGIKA
VTPDGVIGEDGQEYKCDAIIWATGFQSTEFLTPMQVYGRNGLSLNQAWKDGAEAFKGMAVSGFPNLFLLYGPNTNLGHNS
IILMVEHQIHYMIQCIDKIAEKGVAAIDVTPSAMTAYNVRVQSEIAKTVWASDCHSWYKNEAGKVTNNWYGKTTDYKKET
RTPDWTDFEVVKG

Sequences:

>Translated_493_residues
MDQAVNKATTRIAILGAGMSGLGAAAKLKEAGYSVIDIFEKSGGVGGTWRDNTYPGCGCDVPSHLYSYSFELNPDWDYKW
SLQPQILKYFEDFADKYDVRRHCRFNTEITECRWDDAANSWTLTDRAGKTYTADVLISGLGQLNIPHTPNFPGLDTFKGG
AFHSARWDHSVGLKGKTVAVIGNGPSAVQFVPEIQKVVGKMLSFQRSPAWCRPRGQRAYDAKAKKYFAGADWRINWYRWR
IRAFADFGFGAFLQKSPLGLADSMKKMCQKHLEDQVQDPVLREKLTPDFEPGCKRILISDDYYPALAKPNVDVLRQGIKA
VTPDGVIGEDGQEYKCDAIIWATGFQSTEFLTPMQVYGRNGLSLNQAWKDGAEAFKGMAVSGFPNLFLLYGPNTNLGHNS
IILMVEHQIHYMIQCIDKIAEKGVAAIDVTPSAMTAYNVRVQSEIAKTVWASDCHSWYKNEAGKVTNNWYGKTTDYKKET
RTPDWTDFEVVKG
>Mature_493_residues
MDQAVNKATTRIAILGAGMSGLGAAAKLKEAGYSVIDIFEKSGGVGGTWRDNTYPGCGCDVPSHLYSYSFELNPDWDYKW
SLQPQILKYFEDFADKYDVRRHCRFNTEITECRWDDAANSWTLTDRAGKTYTADVLISGLGQLNIPHTPNFPGLDTFKGG
AFHSARWDHSVGLKGKTVAVIGNGPSAVQFVPEIQKVVGKMLSFQRSPAWCRPRGQRAYDAKAKKYFAGADWRINWYRWR
IRAFADFGFGAFLQKSPLGLADSMKKMCQKHLEDQVQDPVLREKLTPDFEPGCKRILISDDYYPALAKPNVDVLRQGIKA
VTPDGVIGEDGQEYKCDAIIWATGFQSTEFLTPMQVYGRNGLSLNQAWKDGAEAFKGMAVSGFPNLFLLYGPNTNLGHNS
IILMVEHQIHYMIQCIDKIAEKGVAAIDVTPSAMTAYNVRVQSEIAKTVWASDCHSWYKNEAGKVTNNWYGKTTDYKKET
RTPDWTDFEVVKG

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=374, Percent_Identity=25.4010695187166, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI221316672, Length=356, Percent_Identity=26.4044943820225, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI221316674, Length=356, Percent_Identity=26.4044943820225, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI4503755, Length=222, Percent_Identity=27.9279279279279, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI50541965, Length=376, Percent_Identity=25.531914893617, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI50541961, Length=376, Percent_Identity=25.531914893617, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI221316678, Length=249, Percent_Identity=28.5140562248996, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4503759, Length=223, Percent_Identity=26.0089686098655, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25145785, Length=350, Percent_Identity=24, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17541300, Length=220, Percent_Identity=24.5454545454545, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19922866, Length=211, Percent_Identity=25.5924170616114, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19921694, Length=215, Percent_Identity=23.7209302325581, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 55186; Mature: 55186

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQAVNKATTRIAILGAGMSGLGAAAKLKEAGYSVIDIFEKSGGVGGTWRDNTYPGCGCD
CCCHHHHHHEEEEEEECCCCCCCHHHHHHHCCCCEEEHHHHCCCCCCCCCCCCCCCCCCC
VPSHLYSYSFELNPDWDYKWSLQPQILKYFEDFADKYDVRRHCRFNTEITECRWDDAANS
CCHHHHEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCC
WTLTDRAGKTYTADVLISGLGQLNIPHTPNFPGLDTFKGGAFHSARWDHSVGLKGKTVAV
EEEECCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
IGNGPSAVQFVPEIQKVVGKMLSFQRSPAWCRPRGQRAYDAKAKKYFAGADWRINWYRWR
ECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHEECCCCEEEEEEEEE
IRAFADFGFGAFLQKSPLGLADSMKKMCQKHLEDQVQDPVLREKLTPDFEPGCKRILISD
EEEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCEEEECC
DYYPALAKPNVDVLRQGIKAVTPDGVIGEDGQEYKCDAIIWATGFQSTEFLTPMQVYGRN
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHCCC
GLSLNQAWKDGAEAFKGMAVSGFPNLFLLYGPNTNLGHNSIILMVEHQIHYMIQCIDKIA
CCCHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHH
EKGVAAIDVTPSAMTAYNVRVQSEIAKTVWASDCHSWYKNEAGKVTNNWYGKTTDYKKET
HCCCEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHC
RTPDWTDFEVVKG
CCCCCCCEEEECC
>Mature Secondary Structure
MDQAVNKATTRIAILGAGMSGLGAAAKLKEAGYSVIDIFEKSGGVGGTWRDNTYPGCGCD
CCCHHHHHHEEEEEEECCCCCCCHHHHHHHCCCCEEEHHHHCCCCCCCCCCCCCCCCCCC
VPSHLYSYSFELNPDWDYKWSLQPQILKYFEDFADKYDVRRHCRFNTEITECRWDDAANS
CCHHHHEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCC
WTLTDRAGKTYTADVLISGLGQLNIPHTPNFPGLDTFKGGAFHSARWDHSVGLKGKTVAV
EEEECCCCCEEEHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
IGNGPSAVQFVPEIQKVVGKMLSFQRSPAWCRPRGQRAYDAKAKKYFAGADWRINWYRWR
ECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHEECCCCEEEEEEEEE
IRAFADFGFGAFLQKSPLGLADSMKKMCQKHLEDQVQDPVLREKLTPDFEPGCKRILISD
EEEEECCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCEEEECC
DYYPALAKPNVDVLRQGIKAVTPDGVIGEDGQEYKCDAIIWATGFQSTEFLTPMQVYGRN
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHCCC
GLSLNQAWKDGAEAFKGMAVSGFPNLFLLYGPNTNLGHNSIILMVEHQIHYMIQCIDKIA
CCCHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCCCEEEEEEEHHHHHHHHHHHHHH
EKGVAAIDVTPSAMTAYNVRVQSEIAKTVWASDCHSWYKNEAGKVTNNWYGKTTDYKKET
HCCCEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHC
RTPDWTDFEVVKG
CCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]