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The map label for this gene is 114799334

Identifier: 114799334

GI number: 114799334

Start: 3428377

End: 3429714

Strand: Direct

Name: 114799334

Synonym: HNE_3264

Alternate gene names: NA

Gene position: 3428377-3429714 (Clockwise)

Preceding gene: 114798792

Following gene: 114800138

Centisome position: 92.53

GC content: 62.63

Gene sequence:

>1338_bases
ATGACATCTGCCACCCCGGATACGGTTTACGCCGCGCCTGCCGAATGGGTCGCGCGGGGGGCTGGCGCGCAGGGAAACCT
TTTCCTGACCGGACGGGCGGGCACGGGCAAAACCACATTGCTGCGTAAATTCCTGGCCGAAGCGGGCGAGAAAGCTGTTG
TACTGGCGCCGACAGGCGTGGCGGCGATGAACGCGGGCGGACAGACGATCCATTCCTTTTTCAAGCTGCCGCCGCGCCTG
GTCGAACCCCAGGATGTGCGCCGCCTGCCCAATGCGCGGGTGGTGCGGGCCGTGGAAACGGTGGTGATCGACGAGATTTC
GATGGTGCGCGCCGACATGCTGGACGCCATCGACCGCAGCCTGAAGCTGAACCGGGGATCGAAGCGGCCATTCGGCGGGG
CACGGATGATCCTCTCGGGCGACCTGCATCAGCTGCCACCTGTAGTATCCTCTCAGGAGGGGCCGATCCTGGCTGACCGG
TATGGCGGCTCCTACTTTTTCAATGCGCCGATTTTCCGCGAGGCGGAGTTTTCGCTGCTGGCCCTGAAACATGTGTTCCG
CCAGGCAGAGCCGCGCTTTCTGGCTCTGCTGGGCGCGCTGCGCTCTGGCCGGGTGAAGCCCTCGGATGAGGCCATCCTGC
AAGGGCTGGTGTCGGGGCGCAGCGCAGCGGACGCTTCCGATACGCATGTCGTGCTGACGCCGAACAATGCCAATGCCTTC
CGCATCAATCAGAACCGGCTGGCGGGCCTGAAGGGTGAGCGAAAGAGCTTCCCGGCCACTGTGCAGGGACAGTTCGACGA
GAAAAGCTTTCCGACCGAGATGGACCTGGAATTGCGGGTTGGCGCGCGGGTGATGCTGATCAAGAACGATCCGGAAGGGC
GCTGGGTGAACGGCTCTCTGGGCATCGTTGAAGGGTTTACCTCACGCACGGTGATCGTCTCCATAGATGGGCGGGTCTAT
GAGATCGAGCCGACGGCCTGGGAGAAATACCGCTACGATTTCGAGATGGATTCGAAGAAGGTGAAGCGTGAAGTGGTGGG
CACCTTCAAGCAGGTGCCGCTGCGGCTGGCCTATGCCGTGACCATCCACAAGGCGCAGGGCCTCACCCTGGACAAGGTGT
TCATCGACTTTGATTCCGGAATGTTCGCCCACGGACAGGCGTATGTGGCCTTCTCCCGCGCGCGCACGCTGGAGGGGCTT
GAAATCTCCCGCCCCCTGCGCCCGCGCGACCTTGTGCTGGACCGGGAAGCCTTTGCCTTTGGCGAGTTGGAAAAGATCGA
CGAGACGCCCGCTTACCTTCTGGCGAAATTCCGCAAGGATGAAGGCGTTCTGGTTTAG

Upstream 100 bases:

>100_bases
ATCGCGCGGCGCGCCTATGAGGCGCTCGGCTGGCAGGTTGTGGCCAGCACCGGCGGATCAGGCCGCGCGCGCCAGATGCG
CCTTGTCGGCCCCTGAGGGG

Downstream 100 bases:

>100_bases
CCTGCCTCAGGCGAGACGGCGGATTTCTTCTGCCAGATCGCGTTCTTTGTCGGTCACGATTTTCTCAAGGACGCGCACGC
GATCCTTCAGGCGGCCGATT

Product: hypothetical protein

Products: NA

Alternate protein names: Helicase; TPR Domain Protein; TPR Domain-Containing Protein; ATPase; Exonuclease V Subunit Alpha; 5-3' DNA Helicase; Helicase-Related Protein; Helicase RecD/TraA Family; Aaa ATPase; Glycosysltransferase; Hrdc Domain Protein; Helicase-Family Protein; Helicase Protein; HRDC Domain Protein; RecD-Like Exodeoxyribonuclease V Alpha Chain; RRM3/PIF1 Helicase-Like Protein; ATP-Dependent ExoDNAse Alpha Subunit; DNA Helicase AAA ATPase; DNA Helicase/AAA ATPase

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTSATPDTVYAAPAEWVARGAGAQGNLFLTGRAGTGKTTLLRKFLAEAGEKAVVLAPTGVAAMNAGGQTIHSFFKLPPRL
VEPQDVRRLPNARVVRAVETVVIDEISMVRADMLDAIDRSLKLNRGSKRPFGGARMILSGDLHQLPPVVSSQEGPILADR
YGGSYFFNAPIFREAEFSLLALKHVFRQAEPRFLALLGALRSGRVKPSDEAILQGLVSGRSAADASDTHVVLTPNNANAF
RINQNRLAGLKGERKSFPATVQGQFDEKSFPTEMDLELRVGARVMLIKNDPEGRWVNGSLGIVEGFTSRTVIVSIDGRVY
EIEPTAWEKYRYDFEMDSKKVKREVVGTFKQVPLRLAYAVTIHKAQGLTLDKVFIDFDSGMFAHGQAYVAFSRARTLEGL
EISRPLRPRDLVLDREAFAFGELEKIDETPAYLLAKFRKDEGVLV

Sequences:

>Translated_445_residues
MTSATPDTVYAAPAEWVARGAGAQGNLFLTGRAGTGKTTLLRKFLAEAGEKAVVLAPTGVAAMNAGGQTIHSFFKLPPRL
VEPQDVRRLPNARVVRAVETVVIDEISMVRADMLDAIDRSLKLNRGSKRPFGGARMILSGDLHQLPPVVSSQEGPILADR
YGGSYFFNAPIFREAEFSLLALKHVFRQAEPRFLALLGALRSGRVKPSDEAILQGLVSGRSAADASDTHVVLTPNNANAF
RINQNRLAGLKGERKSFPATVQGQFDEKSFPTEMDLELRVGARVMLIKNDPEGRWVNGSLGIVEGFTSRTVIVSIDGRVY
EIEPTAWEKYRYDFEMDSKKVKREVVGTFKQVPLRLAYAVTIHKAQGLTLDKVFIDFDSGMFAHGQAYVAFSRARTLEGL
EISRPLRPRDLVLDREAFAFGELEKIDETPAYLLAKFRKDEGVLV
>Mature_444_residues
TSATPDTVYAAPAEWVARGAGAQGNLFLTGRAGTGKTTLLRKFLAEAGEKAVVLAPTGVAAMNAGGQTIHSFFKLPPRLV
EPQDVRRLPNARVVRAVETVVIDEISMVRADMLDAIDRSLKLNRGSKRPFGGARMILSGDLHQLPPVVSSQEGPILADRY
GGSYFFNAPIFREAEFSLLALKHVFRQAEPRFLALLGALRSGRVKPSDEAILQGLVSGRSAADASDTHVVLTPNNANAFR
INQNRLAGLKGERKSFPATVQGQFDEKSFPTEMDLELRVGARVMLIKNDPEGRWVNGSLGIVEGFTSRTVIVSIDGRVYE
IEPTAWEKYRYDFEMDSKKVKREVVGTFKQVPLRLAYAVTIHKAQGLTLDKVFIDFDSGMFAHGQAYVAFSRARTLEGLE
ISRPLRPRDLVLDREAFAFGELEKIDETPAYLLAKFRKDEGVLV

Specific function: Unknown

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI82546872, Length=394, Percent_Identity=34.2639593908629, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25143421, Length=406, Percent_Identity=32.512315270936, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17533663, Length=429, Percent_Identity=28.6713286713287, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17537113, Length=429, Percent_Identity=28.6713286713287, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17536913, Length=429, Percent_Identity=28.4382284382284, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17537851, Length=429, Percent_Identity=28.4382284382284, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17534623, Length=429, Percent_Identity=28.4382284382284, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17566502, Length=128, Percent_Identity=39.84375, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323579, Length=313, Percent_Identity=32.2683706070287, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321820, Length=319, Percent_Identity=28.5266457680251, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19920652, Length=408, Percent_Identity=33.578431372549, Blast_Score=174, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 48992; Mature: 48861

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSATPDTVYAAPAEWVARGAGAQGNLFLTGRAGTGKTTLLRKFLAEAGEKAVVLAPTGV
CCCCCCCCEEECCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCC
AAMNAGGQTIHSFFKLPPRLVEPQDVRRLPNARVVRAVETVVIDEISMVRADMLDAIDRS
EEECCCHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKLNRGSKRPFGGARMILSGDLHQLPPVVSSQEGPILADRYGGSYFFNAPIFREAEFSLL
HCCCCCCCCCCCCEEEEEECCHHHCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCHHHH
ALKHVFRQAEPRFLALLGALRSGRVKPSDEAILQGLVSGRSAADASDTHVVLTPNNANAF
HHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEE
RINQNRLAGLKGERKSFPATVQGQFDEKSFPTEMDLELRVGARVMLIKNDPEGRWVNGSL
EEECHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEECEEEEEEEECCCCCEECCCC
GIVEGFTSRTVIVSIDGRVYEIEPTAWEKYRYDFEMDSKKVKREVVGTFKQVPLRLAYAV
EEEECCCCCEEEEEECCEEEEECCCCHHHEEECCCCCHHHHHHHHHHHHHHCCEEEEEEE
TIHKAQGLTLDKVFIDFDSGMFAHGQAYVAFSRARTLEGLEISRPLRPRDLVLDREAFAF
EEECCCCCEEEEEEEEECCCCEECCCEEEEEEHHHCCCCCCCCCCCCCHHEEECCHHHHC
GELEKIDETPAYLLAKFRKDEGVLV
CCHHHHCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSATPDTVYAAPAEWVARGAGAQGNLFLTGRAGTGKTTLLRKFLAEAGEKAVVLAPTGV
CCCCCCCEEECCHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCC
AAMNAGGQTIHSFFKLPPRLVEPQDVRRLPNARVVRAVETVVIDEISMVRADMLDAIDRS
EEECCCHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKLNRGSKRPFGGARMILSGDLHQLPPVVSSQEGPILADRYGGSYFFNAPIFREAEFSLL
HCCCCCCCCCCCCEEEEEECCHHHCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCHHHH
ALKHVFRQAEPRFLALLGALRSGRVKPSDEAILQGLVSGRSAADASDTHVVLTPNNANAF
HHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEE
RINQNRLAGLKGERKSFPATVQGQFDEKSFPTEMDLELRVGARVMLIKNDPEGRWVNGSL
EEECHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEECEEEEEEEECCCCCEECCCC
GIVEGFTSRTVIVSIDGRVYEIEPTAWEKYRYDFEMDSKKVKREVVGTFKQVPLRLAYAV
EEEECCCCCEEEEEECCEEEEECCCCHHHEEECCCCCHHHHHHHHHHHHHHCCEEEEEEE
TIHKAQGLTLDKVFIDFDSGMFAHGQAYVAFSRARTLEGLEISRPLRPRDLVLDREAFAF
EEECCCCCEEEEEEEEECCCCEECCCEEEEEEHHHCCCCCCCCCCCCCHHEEECCHHHHC
GELEKIDETPAYLLAKFRKDEGVLV
CCHHHHCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA