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The map label for this gene is kdsB [H]

Identifier: 114799298

GI number: 114799298

Start: 3063449

End: 3064261

Strand: Direct

Name: kdsB [H]

Synonym: HNE_2908

Alternate gene names: 114799298

Gene position: 3063449-3064261 (Clockwise)

Preceding gene: 114800102

Following gene: 114798766

Centisome position: 82.68

GC content: 62.73

Gene sequence:

>813_bases
ATGCAGACATTGATCGTTGTCCCTGCCCGCTATGGCTCCACCCGGCTGCCGGGCAAACCGCTCGCCAAGATCGCCGGAAA
AACGATGGTCAGCCGCGTCGCCGACCTTGCGCGGCGCGCGGCGGCCAGACTTGGCAAGGGCGCCGAGTTTGTCGTTGCCA
CCGATGACACGCGCATCCTGCAATATTGCCGCGACAACAACATAAATGTGGTGATGACCGACCCGGCCCTGCCATCGGGA
TCAGACCGGGCGCTCGCGGCTGTGGACGGCTTGGGCATGAGCCCGGATTTCGTGGTGAACCTGCAAGGCGACGCGCCGTT
CACACCGGCCGAGCATGTCGTAGCCGTCGTCGAGGCTCTGGAAAAATCAGGCACCGACGCCGCAACGCCTTACATCCGGC
TCAGCTGGGCCGCGCTTGATCAGCTGCGAAATCACAAGGCGCAGACCCCTTTTTCGGGCACCACGCTGGTCAAAGATCCC
AAGGGCCGGGCCATCTGGTTTTCCAAGATCATCCTGCCCGCCATCCGCAAGGAACCGGAACTGCGCAAGCTGAACGATCT
CTCGCCGGTCTGCCAACATGTCGGCCTCTATGGCTTCCGCCTTGATACGCTGCGCCGTTATTGCGCCCTTCCCGAAAGCT
ATTATGAGCGGCTGGAAGGCCTTGAGCAGCTGCGCCTGATCGAGAACGGGTTCAGCGTCCAGGCTGTGGAAGTCAAACCC
GGCAAGATCGCCATCCCCGGCATCGATACGGCCGAAGACATTGCCCTTGCCGAGCGCCTTGTGGCCGAGTTCGGCGAGCC
GGACGTCGCCTGA

Upstream 100 bases:

>100_bases
GCTGCAATGGGTCGGGCCGATCCTCGCACTGGTTCAGGTAATGCAGGATGACGGGCAGCTCCAGTCCGGCCCGCGCCCCT
GATACGGGGGAACCTGAACC

Downstream 100 bases:

>100_bases
CAGCATGGCCCGGCTATTTATCGTCCGGCACGGCAATACCTTCGACAAGGGCGATACCGTCACGCGTGTTGGCGCACGCA
CGGACCTGCCATTGTCGATC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MQTLIVVPARYGSTRLPGKPLAKIAGKTMVSRVADLARRAAARLGKGAEFVVATDDTRILQYCRDNNINVVMTDPALPSG
SDRALAAVDGLGMSPDFVVNLQGDAPFTPAEHVVAVVEALEKSGTDAATPYIRLSWAALDQLRNHKAQTPFSGTTLVKDP
KGRAIWFSKIILPAIRKEPELRKLNDLSPVCQHVGLYGFRLDTLRRYCALPESYYERLEGLEQLRLIENGFSVQAVEVKP
GKIAIPGIDTAEDIALAERLVAEFGEPDVA

Sequences:

>Translated_270_residues
MQTLIVVPARYGSTRLPGKPLAKIAGKTMVSRVADLARRAAARLGKGAEFVVATDDTRILQYCRDNNINVVMTDPALPSG
SDRALAAVDGLGMSPDFVVNLQGDAPFTPAEHVVAVVEALEKSGTDAATPYIRLSWAALDQLRNHKAQTPFSGTTLVKDP
KGRAIWFSKIILPAIRKEPELRKLNDLSPVCQHVGLYGFRLDTLRRYCALPESYYERLEGLEQLRLIENGFSVQAVEVKP
GKIAIPGIDTAEDIALAERLVAEFGEPDVA
>Mature_270_residues
MQTLIVVPARYGSTRLPGKPLAKIAGKTMVSRVADLARRAAARLGKGAEFVVATDDTRILQYCRDNNINVVMTDPALPSG
SDRALAAVDGLGMSPDFVVNLQGDAPFTPAEHVVAVVEALEKSGTDAATPYIRLSWAALDQLRNHKAQTPFSGTTLVKDP
KGRAIWFSKIILPAIRKEPELRKLNDLSPVCQHVGLYGFRLDTLRRYCALPESYYERLEGLEQLRLIENGFSVQAVEVKP
GKIAIPGIDTAEDIALAERLVAEFGEPDVA

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=271, Percent_Identity=32.8413284132841, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 29376; Mature: 29376

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLIVVPARYGSTRLPGKPLAKIAGKTMVSRVADLARRAAARLGKGAEFVVATDDTRIL
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
QYCRDNNINVVMTDPALPSGSDRALAAVDGLGMSPDFVVNLQGDAPFTPAEHVVAVVEAL
HHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
EKSGTDAATPYIRLSWAALDQLRNHKAQTPFSGTTLVKDPKGRAIWFSKIILPAIRKEPE
HHCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEHHHHHHHHHHCCCCH
LRKLNDLSPVCQHVGLYGFRLDTLRRYCALPESYYERLEGLEQLRLIENGFSVQAVEVKP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GKIAIPGIDTAEDIALAERLVAEFGEPDVA
CEEEECCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQTLIVVPARYGSTRLPGKPLAKIAGKTMVSRVADLARRAAARLGKGAEFVVATDDTRIL
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
QYCRDNNINVVMTDPALPSGSDRALAAVDGLGMSPDFVVNLQGDAPFTPAEHVVAVVEAL
HHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
EKSGTDAATPYIRLSWAALDQLRNHKAQTPFSGTTLVKDPKGRAIWFSKIILPAIRKEPE
HHCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEHHHHHHHHHHCCCCH
LRKLNDLSPVCQHVGLYGFRLDTLRRYCALPESYYERLEGLEQLRLIENGFSVQAVEVKP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECC
GKIAIPGIDTAEDIALAERLVAEFGEPDVA
CEEEECCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA