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The map label for this gene is tsf

Identifier: 114799266

GI number: 114799266

Start: 1812975

End: 1813880

Strand: Direct

Name: tsf

Synonym: HNE_1769

Alternate gene names: 114799266

Gene position: 1812975-1813880 (Clockwise)

Preceding gene: 114799137

Following gene: 114798646

Centisome position: 48.93

GC content: 55.85

Gene sequence:

>906_bases
ATGGCTGAGATTACTGCTGCACTTGTGAAAGAACTGCGCGAAAAAACGGGCGCAGGCATGATGGATGCGAAGAAAGCACT
GGTCGAAAATAATGGCGACCAGGCAGCTGCAATTGAGTGGCTGCGCGCAAAGGGACTGTCCAAGGCCGCCAAGAAATCTG
ATCGCGCCGCGGCTGAGGGGCTCGTTGCGGTCAAGTTGTCTGACGACGGCAAGTCCGGCGCGATTGTCGAACTCAATGCT
GAAACCGATTTCGTCGCACGCAACGAGATTTTCCAGAAGTCCCTCGACGGGATCGCTGTCGCTGCCCTGAAGGCGGATGG
TACGGTTGAGGCGGTTTCTGCTGCAGCTTCGCCAGATGGTGAAGGCTCCGTGGATGATCTGATTAAGCGCATGATCGCTA
CAATTGGCGAAAACATGACCTTGCGCCGTGTTGCAAAGCTCTCGGCAACCGGCCGGGTAGCGGCTTATACCCACAACGCT
GTTGTGCCGGGTATGGGCAAGGTTGGTGTGCTCGTTGCCCTTGACGGTTCGGGTGACCTTGAAGACGCTGGCCGGAAGGT
TGCTATGCACATTGCGGCAACGTCTCCCGCAGCGGCAACCACTGAAGAGCTTGATCCGGCGCTTGTCGAATCAGAGAAGC
GCGTACTGACCGAGCAAGCTCGTGAGAGCGGCAAGCCTGACGCTGTCATTGAAAAGATGATCGTTGGCCGCATGCAGAAA
TTCTACAAAGAGGTCGTTCTGGCCGAGCAGCCCTTCATCATGGACCCAGACAAAACGGTTGGGGAATTCCTGAAAGAGCA
GGGCGCTACCTTGAAAGGGTTTGTTCATTACAAACTCGGTGAAGGGGTAGAGAAAGCTGCGGACAACTTCGCAGATGAAG
TCGCTGCACTCACAAAAGGCGCCTGA

Upstream 100 bases:

>100_bases
TCGCGTCGCTTGCAGACGCTGATGTCAAACTGGCTGACGAAGAAGCTGCGGGCGAAGCTTAATCGCTTCTTCTGCCAACC
CAAGATGAAGGAACAATCTC

Downstream 100 bases:

>100_bases
TCGGGCTTGCCTTTCAGCCCATGAGGGGCTTTGAACAATCCCGGCTGCCCCTAGGAGCGGCCGGGATTATTTTATCCAGC
GCTCAGAATACAAGGGATTG

Product: translation elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MAEITAALVKELREKTGAGMMDAKKALVENNGDQAAAIEWLRAKGLSKAAKKSDRAAAEGLVAVKLSDDGKSGAIVELNA
ETDFVARNEIFQKSLDGIAVAALKADGTVEAVSAAASPDGEGSVDDLIKRMIATIGENMTLRRVAKLSATGRVAAYTHNA
VVPGMGKVGVLVALDGSGDLEDAGRKVAMHIAATSPAAATTEELDPALVESEKRVLTEQARESGKPDAVIEKMIVGRMQK
FYKEVVLAEQPFIMDPDKTVGEFLKEQGATLKGFVHYKLGEGVEKAADNFADEVAALTKGA

Sequences:

>Translated_301_residues
MAEITAALVKELREKTGAGMMDAKKALVENNGDQAAAIEWLRAKGLSKAAKKSDRAAAEGLVAVKLSDDGKSGAIVELNA
ETDFVARNEIFQKSLDGIAVAALKADGTVEAVSAAASPDGEGSVDDLIKRMIATIGENMTLRRVAKLSATGRVAAYTHNA
VVPGMGKVGVLVALDGSGDLEDAGRKVAMHIAATSPAAATTEELDPALVESEKRVLTEQARESGKPDAVIEKMIVGRMQK
FYKEVVLAEQPFIMDPDKTVGEFLKEQGATLKGFVHYKLGEGVEKAADNFADEVAALTKGA
>Mature_300_residues
AEITAALVKELREKTGAGMMDAKKALVENNGDQAAAIEWLRAKGLSKAAKKSDRAAAEGLVAVKLSDDGKSGAIVELNAE
TDFVARNEIFQKSLDGIAVAALKADGTVEAVSAAASPDGEGSVDDLIKRMIATIGENMTLRRVAKLSATGRVAAYTHNAV
VPGMGKVGVLVALDGSGDLEDAGRKVAMHIAATSPAAATTEELDPALVESEKRVLTEQARESGKPDAVIEKMIVGRMQKF
YKEVVLAEQPFIMDPDKTVGEFLKEQGATLKGFVHYKLGEGVEKAADNFADEVAALTKGA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=300, Percent_Identity=30, Blast_Score=121, Evalue=7e-28,
Organism=Homo sapiens, GI291084500, Length=321, Percent_Identity=28.3489096573209, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI291084502, Length=138, Percent_Identity=35.5072463768116, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI291084498, Length=116, Percent_Identity=37.0689655172414, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786366, Length=299, Percent_Identity=45.4849498327759, Blast_Score=227, Evalue=9e-61,
Organism=Caenorhabditis elegans, GI17561440, Length=296, Percent_Identity=30.4054054054054, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19921466, Length=305, Percent_Identity=29.8360655737705, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_HYPNA (Q0C1C0)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760473.1
- ProteinModelPortal:   Q0C1C0
- SMR:   Q0C1C0
- STRING:   Q0C1C0
- GeneID:   4288581
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1769
- NMPDR:   fig|228405.5.peg.1703
- TIGR:   HNE_1769
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q0C1C0
- BioCyc:   HNEP81032:HNE_1769-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31552; Mature: 31421

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEITAALVKELREKTGAGMMDAKKALVENNGDQAAAIEWLRAKGLSKAAKKSDRAAAEG
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCC
LVAVKLSDDGKSGAIVELNAETDFVARNEIFQKSLDGIAVAALKADGTVEAVSAAASPDG
EEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCC
EGSVDDLIKRMIATIGENMTLRRVAKLSATGRVAAYTHNAVVPGMGKVGVLVALDGSGDL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCH
EDAGRKVAMHIAATSPAAATTEELDPALVESEKRVLTEQARESGKPDAVIEKMIVGRMQK
HHHCCEEEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FYKEVVLAEQPFIMDPDKTVGEFLKEQGATLKGFVHYKLGEGVEKAADNFADEVAALTKG
HHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEHHCCCHHHHHHHHHHHHHHHHCC
A
C
>Mature Secondary Structure 
AEITAALVKELREKTGAGMMDAKKALVENNGDQAAAIEWLRAKGLSKAAKKSDRAAAEG
CHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCC
LVAVKLSDDGKSGAIVELNAETDFVARNEIFQKSLDGIAVAALKADGTVEAVSAAASPDG
EEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCC
EGSVDDLIKRMIATIGENMTLRRVAKLSATGRVAAYTHNAVVPGMGKVGVLVALDGSGDL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCH
EDAGRKVAMHIAATSPAAATTEELDPALVESEKRVLTEQARESGKPDAVIEKMIVGRMQK
HHHCCEEEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FYKEVVLAEQPFIMDPDKTVGEFLKEQGATLKGFVHYKLGEGVEKAADNFADEVAALTKG
HHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEHHCCCHHHHHHHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA