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The map label for this gene is hfaC [H]

Identifier: 114799256

GI number: 114799256

Start: 760691

End: 762517

Strand: Reverse

Name: hfaC [H]

Synonym: HNE_0754

Alternate gene names: 114799256

Gene position: 762517-760691 (Counterclockwise)

Preceding gene: 114800237

Following gene: 114799424

Centisome position: 20.58

GC content: 64.2

Gene sequence:

>1827_bases
ATGGCCCAGCCCCCACTGATTACCCTCACCGATGTCCGCCTTTCTTTCGGCAATACGCCCCTGTTCGAGGGCGTGACGCT
GGCTTTGTCCAAGGGGGAGCGGGCGGCGCTGGTGGGGCGCAACGGGGCGGGCAAGTCGACGCTCATGAAGATCATCTCGC
AGCAGGCCGAGCCGGATTCCGGCGCGGTCTGGCGACAGCCCGGCGTGACCTTTGCCAATGTCGCGCAGGAGCCGGATCTG
GCGGGATATGCCACCGTGCTCGATTATGCGACCGACGGGCTGGAGGCGGCCTATATGGCTGAGGCCGAGCTGATGGAGTT
CGGCATTGATCCGGCCGCTGATCCCAAGACGCTGTCTGGCGGGCAGATGCGCCGGGCCGCGCTCGCCAAGGCGTTTGCGC
AGGAGCCGACGATCCTGCTGCTGGACGAGCCGACAAACCATCTCGACGTGCCGATGATCGAGTTCCTGGAGGGGCGCCTG
AAGGCGTTCAACGGCGTTGTTCTGGTGGTCAGCCATGACCGCCGGTTTCTGGAGAATATCTCGACCAACACGCTGTGGCT
GCGCCAGGGCAAGGTGCTGAAAAGCCCGGAAGGCTATGTGAAGTTTGATCAGTGGGCCGAGCAGATCGAGGAAGAGGATG
AACGTCAGCTCAAACGCATGACGACCCACCTGAAAGATGAGCAGCACTGGCTGGCGCGCGGCGTGACGGCGCGGCGCAAA
CGCAATCAGGGACGCCTTGCCCGGCTGAGGCAGCTGAAAACCGAGCATGCCCAGGTGCGCAGCGCGCTGAACGATCGCAA
GGCTGCCGCCACAATCACGGCGGATGCGGGCGACTCGCTAAGCAAGAAGGTGATCGAGGCCAAGGGCCTGTTCAAAACCT
ATCAGACCCCGGAGGGGGATGACCTCGTTATCGCAACCGATTTGTCGCTGCGCATCCTGCGCGGAGACCGGATCGGCATC
ATCGGCCCCAATGGCGCGGGCAAGACGACGCTGGTGCGCCTGCTGCTGGGCGAGATCGCGCCGGACGCCGGATCGGTGCA
GCATTCCAAGACATTGCAGGTGACCTATCAGGATCAGACGCGGGCCACGCTCGACGCGAAGGATACGATCTGGGAAGCGC
TCGCCCCGGAAGGCGGGGACTCGATCACCGTGCAGGGGCATCAGCGCCATGTGGCGGCCTATGCCAAGGACTTCCTGTTC
AAGCCCGAGCAGCTGCGCCAGCCTGTCGGCGCGCTGTCGGGCGGGGAACGCAACCGGCTGGCCCTCGCCATTGGCCTGGC
GCGCACGTCAAACCTTCTGGTGATGGACGAACCGACCAACGATCTCGACATGCAGACGCTCGACCTGCTGGAAGACATGC
TGCTGAACTATGAGGGCACGCTGATCCTGGTGAGCCATGACCGCGCGTTTCTCGACGCGACCGTGACGAGCTGCCTCTCG
CCGATTGGCGGAGGCGAGTGGATACAGACGGCCGGCGGCTGGAGCGACGCGCAGGAGCAACTGAAAGATGTCCGCCTCAA
GGGCGCGCCGAAAGCGGCGCCGGCCAAGAGCGCTTCCCCGGCCACGGCCCCGCCAAAACCCAAGGCGCAGGTAAAGCTCT
CCTTCAAGGATGAGCACCGGCAGAAGGAAATCGATGGGCTGATCCCGAAGCTGCAGGCGGAAATCGCCAAGCTTGAAACT
GAGCTCGCCGATGCGGCGCTTTACGGGCGCGATCCGGCAGCCTTCAACAAGAAGTCTGCCCGCATTGGCACCGCCCGCGA
TGAGCTTGAGGGGATCGAGCTGGAATGGCTGGAAATCGAGGAGAAGCGGGCTGGCCTTGACGGCTGA

Upstream 100 bases:

>100_bases
GGGCGATCTGTCGGAAGGCGCGTGGCGCCTGCTGACAGAGGCCGAACGTGCGGGGCTTGCCCCCTAGCGTCCACGCGCGT
CAGCGGCTATCTCCCCGGCC

Downstream 100 bases:

>100_bases
ACCGCCTCTTTCAAGGCAAACGCTTCGTTAACGCGGGCCGGGTAGCCTGCCCTTCGGATAAATGCCGGGAGTCCGAACCG
ATGCGCCTTGCCATGCTGAT

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: Protein HfaC [H]

Number of amino acids: Translated: 608; Mature: 607

Protein sequence:

>608_residues
MAQPPLITLTDVRLSFGNTPLFEGVTLALSKGERAALVGRNGAGKSTLMKIISQQAEPDSGAVWRQPGVTFANVAQEPDL
AGYATVLDYATDGLEAAYMAEAELMEFGIDPAADPKTLSGGQMRRAALAKAFAQEPTILLLDEPTNHLDVPMIEFLEGRL
KAFNGVVLVVSHDRRFLENISTNTLWLRQGKVLKSPEGYVKFDQWAEQIEEEDERQLKRMTTHLKDEQHWLARGVTARRK
RNQGRLARLRQLKTEHAQVRSALNDRKAAATITADAGDSLSKKVIEAKGLFKTYQTPEGDDLVIATDLSLRILRGDRIGI
IGPNGAGKTTLVRLLLGEIAPDAGSVQHSKTLQVTYQDQTRATLDAKDTIWEALAPEGGDSITVQGHQRHVAAYAKDFLF
KPEQLRQPVGALSGGERNRLALAIGLARTSNLLVMDEPTNDLDMQTLDLLEDMLLNYEGTLILVSHDRAFLDATVTSCLS
PIGGGEWIQTAGGWSDAQEQLKDVRLKGAPKAAPAKSASPATAPPKPKAQVKLSFKDEHRQKEIDGLIPKLQAEIAKLET
ELADAALYGRDPAAFNKKSARIGTARDELEGIELEWLEIEEKRAGLDG

Sequences:

>Translated_608_residues
MAQPPLITLTDVRLSFGNTPLFEGVTLALSKGERAALVGRNGAGKSTLMKIISQQAEPDSGAVWRQPGVTFANVAQEPDL
AGYATVLDYATDGLEAAYMAEAELMEFGIDPAADPKTLSGGQMRRAALAKAFAQEPTILLLDEPTNHLDVPMIEFLEGRL
KAFNGVVLVVSHDRRFLENISTNTLWLRQGKVLKSPEGYVKFDQWAEQIEEEDERQLKRMTTHLKDEQHWLARGVTARRK
RNQGRLARLRQLKTEHAQVRSALNDRKAAATITADAGDSLSKKVIEAKGLFKTYQTPEGDDLVIATDLSLRILRGDRIGI
IGPNGAGKTTLVRLLLGEIAPDAGSVQHSKTLQVTYQDQTRATLDAKDTIWEALAPEGGDSITVQGHQRHVAAYAKDFLF
KPEQLRQPVGALSGGERNRLALAIGLARTSNLLVMDEPTNDLDMQTLDLLEDMLLNYEGTLILVSHDRAFLDATVTSCLS
PIGGGEWIQTAGGWSDAQEQLKDVRLKGAPKAAPAKSASPATAPPKPKAQVKLSFKDEHRQKEIDGLIPKLQAEIAKLET
ELADAALYGRDPAAFNKKSARIGTARDELEGIELEWLEIEEKRAGLDG
>Mature_607_residues
AQPPLITLTDVRLSFGNTPLFEGVTLALSKGERAALVGRNGAGKSTLMKIISQQAEPDSGAVWRQPGVTFANVAQEPDLA
GYATVLDYATDGLEAAYMAEAELMEFGIDPAADPKTLSGGQMRRAALAKAFAQEPTILLLDEPTNHLDVPMIEFLEGRLK
AFNGVVLVVSHDRRFLENISTNTLWLRQGKVLKSPEGYVKFDQWAEQIEEEDERQLKRMTTHLKDEQHWLARGVTARRKR
NQGRLARLRQLKTEHAQVRSALNDRKAAATITADAGDSLSKKVIEAKGLFKTYQTPEGDDLVIATDLSLRILRGDRIGII
GPNGAGKTTLVRLLLGEIAPDAGSVQHSKTLQVTYQDQTRATLDAKDTIWEALAPEGGDSITVQGHQRHVAAYAKDFLFK
PEQLRQPVGALSGGERNRLALAIGLARTSNLLVMDEPTNDLDMQTLDLLEDMLLNYEGTLILVSHDRAFLDATVTSCLSP
IGGGEWIQTAGGWSDAQEQLKDVRLKGAPKAAPAKSASPATAPPKPKAQVKLSFKDEHRQKEIDGLIPKLQAEIAKLETE
LADAALYGRDPAAFNKKSARIGTARDELEGIELEWLEIEEKRAGLDG

Specific function: Involved in attachment of the holdfast to the cell. The holdfast is a structure that allows the bacteria to firmly adhere to surfaces [H]

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=566, Percent_Identity=29.3286219081272, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI10947137, Length=500, Percent_Identity=29.8, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI27881506, Length=500, Percent_Identity=29.8, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI10947135, Length=519, Percent_Identity=28.3236994219653, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI69354671, Length=519, Percent_Identity=28.3236994219653, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1787182, Length=642, Percent_Identity=36.6043613707165, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI2367384, Length=541, Percent_Identity=32.1626617375231, Blast_Score=249, Evalue=5e-67,
Organism=Escherichia coli, GI1787041, Length=539, Percent_Identity=29.3135435992579, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1789751, Length=650, Percent_Identity=28.3076923076923, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI1787758, Length=173, Percent_Identity=31.7919075144509, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789873, Length=204, Percent_Identity=30.8823529411765, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787029, Length=217, Percent_Identity=26.2672811059908, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788225, Length=212, Percent_Identity=26.4150943396226, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788761, Length=217, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788897, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786803, Length=209, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788644, Length=225, Percent_Identity=28.8888888888889, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI87081709, Length=227, Percent_Identity=25.1101321585903, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788165, Length=184, Percent_Identity=29.8913043478261, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787370, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787712, Length=209, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786253, Length=213, Percent_Identity=29.1079812206573, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081791, Length=217, Percent_Identity=26.7281105990783, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787089, Length=219, Percent_Identity=25.5707762557078, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787164, Length=204, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786872, Length=225, Percent_Identity=28, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790467, Length=216, Percent_Identity=27.3148148148148, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786703, Length=182, Percent_Identity=31.3186813186813, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=206, Percent_Identity=28.1553398058252, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082267, Length=188, Percent_Identity=27.1276595744681, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786563, Length=160, Percent_Identity=28.75, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI87082064, Length=174, Percent_Identity=32.183908045977, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1789032, Length=201, Percent_Identity=29.3532338308458, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=498, Percent_Identity=28.9156626506024, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17559834, Length=538, Percent_Identity=26.5799256505576, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17553372, Length=525, Percent_Identity=28.5714285714286, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17533971, Length=175, Percent_Identity=34.8571428571429, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17543740, Length=155, Percent_Identity=33.5483870967742, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=172, Percent_Identity=33.1395348837209, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=522, Percent_Identity=26.6283524904215, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6321121, Length=396, Percent_Identity=27.020202020202, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6325030, Length=358, Percent_Identity=29.8882681564246, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323278, Length=357, Percent_Identity=26.0504201680672, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6324314, Length=171, Percent_Identity=30.9941520467836, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24666836, Length=514, Percent_Identity=28.4046692607004, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI24642252, Length=510, Percent_Identity=27.843137254902, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI18859989, Length=510, Percent_Identity=27.843137254902, Blast_Score=159, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24641342, Length=528, Percent_Identity=27.0833333333333, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI116007184, Length=157, Percent_Identity=30.5732484076433, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221500365, Length=157, Percent_Identity=30.5732484076433, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574259, Length=200, Percent_Identity=27, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648279, Length=173, Percent_Identity=28.9017341040462, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161078426, Length=173, Percent_Identity=28.9017341040462, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 66403; Mature: 66272

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPPLITLTDVRLSFGNTPLFEGVTLALSKGERAALVGRNGAGKSTLMKIISQQAEPDS
CCCCCEEEEEEEEEECCCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCC
GAVWRQPGVTFANVAQEPDLAGYATVLDYATDGLEAAYMAEAELMEFGIDPAADPKTLSG
CCEECCCCCCHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GQMRRAALAKAFAQEPTILLLDEPTNHLDVPMIEFLEGRLKAFNGVVLVVSHDRRFLENI
CHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHCC
STNTLWLRQGKVLKSPEGYVKFDQWAEQIEEEDERQLKRMTTHLKDEQHWLARGVTARRK
CCCEEEEECCCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHH
RNQGRLARLRQLKTEHAQVRSALNDRKAAATITADAGDSLSKKVIEAKGLFKTYQTPEGD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCC
DLVIATDLSLRILRGDRIGIIGPNGAGKTTLVRLLLGEIAPDAGSVQHSKTLQVTYQDQT
CEEEEECCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
RATLDAKDTIWEALAPEGGDSITVQGHQRHVAAYAKDFLFKPEQLRQPVGALSGGERNRL
CEECCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCEE
ALAIGLARTSNLLVMDEPTNDLDMQTLDLLEDMLLNYEGTLILVSHDRAFLDATVTSCLS
EEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHC
PIGGGEWIQTAGGWSDAQEQLKDVRLKGAPKAAPAKSASPATAPPKPKAQVKLSFKDEHR
CCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHH
QKEIDGLIPKLQAEIAKLETELADAALYGRDPAAFNKKSARIGTARDELEGIELEWLEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEEEH
EKRAGLDG
HHHCCCCC
>Mature Secondary Structure 
AQPPLITLTDVRLSFGNTPLFEGVTLALSKGERAALVGRNGAGKSTLMKIISQQAEPDS
CCCCEEEEEEEEEECCCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCC
GAVWRQPGVTFANVAQEPDLAGYATVLDYATDGLEAAYMAEAELMEFGIDPAADPKTLSG
CCEECCCCCCHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GQMRRAALAKAFAQEPTILLLDEPTNHLDVPMIEFLEGRLKAFNGVVLVVSHDRRFLENI
CHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEECCHHHHHCC
STNTLWLRQGKVLKSPEGYVKFDQWAEQIEEEDERQLKRMTTHLKDEQHWLARGVTARRK
CCCEEEEECCCEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHHHH
RNQGRLARLRQLKTEHAQVRSALNDRKAAATITADAGDSLSKKVIEAKGLFKTYQTPEGD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCC
DLVIATDLSLRILRGDRIGIIGPNGAGKTTLVRLLLGEIAPDAGSVQHSKTLQVTYQDQT
CEEEEECCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
RATLDAKDTIWEALAPEGGDSITVQGHQRHVAAYAKDFLFKPEQLRQPVGALSGGERNRL
CEECCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCEE
ALAIGLARTSNLLVMDEPTNDLDMQTLDLLEDMLLNYEGTLILVSHDRAFLDATVTSCLS
EEEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHC
PIGGGEWIQTAGGWSDAQEQLKDVRLKGAPKAAPAKSASPATAPPKPKAQVKLSFKDEHR
CCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECHHHH
QKEIDGLIPKLQAEIAKLETELADAALYGRDPAAFNKKSARIGTARDELEGIELEWLEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEEEH
EKRAGLDG
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647; 8150261 [H]