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The map label for this gene is yfhM [H]

Identifier: 114799194

GI number: 114799194

Start: 3501629

End: 3502576

Strand: Direct

Name: yfhM [H]

Synonym: HNE_3353

Alternate gene names: 114799194

Gene position: 3501629-3502576 (Clockwise)

Preceding gene: 114799283

Following gene: 114798719

Centisome position: 94.51

GC content: 63.82

Gene sequence:

>948_bases
ATGATCACCGTGTCCCTCGTGGCCCTTTCGGGCCTCGGCCTTGGCGCCTGCGTGTCCAGTATGGCCTACACGTCCAAGGT
GGAAGCTGCCTATCCGGCAGAAGGCCGCCAGATCGATGTGGGCGGCCATGACGTCCACGTCCTGGAGCGCGGTCCCGGAA
CGGCCCCTGTCGTTCTGATGATCCACGGGGCCAGCGCCAATGCCCGCGAGTTTACCGGCACCCTTGCCCCGCGCCTTGAG
ACCGACATGCGCGTGCTGATGGCCGACCGGCCGGGCCATGGTTATTCGGAGCGGTTTGACGGGGCAGAGACCCTCGCCGC
CCAAGCCCGCCAGATGGCCGGCCTGCTGGATCAGCTCGCGCCGGACCAGAAGGCGGTCATCGTTGGTCACTCGTTCGGCG
GCGCTGTGGCCCTCCGCATCGCGCTCGACCGGCCAGATCTTGTCTCCGGCCTCGTATTGCTCGCGCCTGTTACCCATGAC
TGGGGTGAAGGCAGCGGCACGGCCTGGTACAATTCCATCGCCGCAAATCCTGTCTTCGGCCCGGTCTTCTCTCAGTTTGT
CCCGATCATCGGCCCGTCTCAGATGAAAGACGGTATCTCCAGCGTCTTTGCCCCGGCCCCTACCCCGCAGGGCTATTATC
AGAACTCCGGTCTCGGGCTTTTGTTGCGCCCGCCAAACTTCCGCGCCAACGCGCAGGATATGACCCGGCTGAAAGACGAA
CTGGCGCAGCAATCTGCCCGGTATGGCGACCTCTCAGTACCGATCACCGTATTTTCCGGCAGCAAGGACACGGTGCTTTC
ACCAAAACTTCACGCCGTCCGGCTCAAGAAGCAGGTGCCTGTTGAAATGGTCATTCTGCCAGACGAGGGGCACATGCCAC
ATCATGGTGAAGGCAGCGCTGTTGCCGGGGCCATCCGGCGGCTGGCGTTTGGCCGCCAGACCCGCTAA

Upstream 100 bases:

>100_bases
GCTACCGCGAAGCGCTCACCATTTATCCGCTGATGCCGCAGGCCAAGGCGGCTGAAGCGCGCCTGACGCTGAAGGCTGAA
GGCCAGGAGCTTTGAAGCGC

Downstream 100 bases:

>100_bases
TAGCCTCCCCTTCGCCTTAAGCCCGGAAAGGACACCTCCATGGACGACAGCTTTGAGCTGACCAAGATCGACGAAACCAC
CCGGGAAAAACTCCGCCAGA

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MITVSLVALSGLGLGACVSSMAYTSKVEAAYPAEGRQIDVGGHDVHVLERGPGTAPVVLMIHGASANAREFTGTLAPRLE
TDMRVLMADRPGHGYSERFDGAETLAAQARQMAGLLDQLAPDQKAVIVGHSFGGAVALRIALDRPDLVSGLVLLAPVTHD
WGEGSGTAWYNSIAANPVFGPVFSQFVPIIGPSQMKDGISSVFAPAPTPQGYYQNSGLGLLLRPPNFRANAQDMTRLKDE
LAQQSARYGDLSVPITVFSGSKDTVLSPKLHAVRLKKQVPVEMVILPDEGHMPHHGEGSAVAGAIRRLAFGRQTR

Sequences:

>Translated_315_residues
MITVSLVALSGLGLGACVSSMAYTSKVEAAYPAEGRQIDVGGHDVHVLERGPGTAPVVLMIHGASANAREFTGTLAPRLE
TDMRVLMADRPGHGYSERFDGAETLAAQARQMAGLLDQLAPDQKAVIVGHSFGGAVALRIALDRPDLVSGLVLLAPVTHD
WGEGSGTAWYNSIAANPVFGPVFSQFVPIIGPSQMKDGISSVFAPAPTPQGYYQNSGLGLLLRPPNFRANAQDMTRLKDE
LAQQSARYGDLSVPITVFSGSKDTVLSPKLHAVRLKKQVPVEMVILPDEGHMPHHGEGSAVAGAIRRLAFGRQTR
>Mature_315_residues
MITVSLVALSGLGLGACVSSMAYTSKVEAAYPAEGRQIDVGGHDVHVLERGPGTAPVVLMIHGASANAREFTGTLAPRLE
TDMRVLMADRPGHGYSERFDGAETLAAQARQMAGLLDQLAPDQKAVIVGHSFGGAVALRIALDRPDLVSGLVLLAPVTHD
WGEGSGTAWYNSIAANPVFGPVFSQFVPIIGPSQMKDGISSVFAPAPTPQGYYQNSGLGLLLRPPNFRANAQDMTRLKDE
LAQQSARYGDLSVPITVFSGSKDTVLSPKLHAVRLKKQVPVEMVILPDEGHMPHHGEGSAVAGAIRRLAFGRQTR

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 33333; Mature: 33333

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVSLVALSGLGLGACVSSMAYTSKVEAAYPAEGRQIDVGGHDVHVLERGPGTAPVVLM
CEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEECCCCCCEEEEE
IHGASANAREFTGTLAPRLETDMRVLMADRPGHGYSERFDGAETLAAQARQMAGLLDQLA
EECCCCCCHHHHCCCCCCCCCCEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHC
PDQKAVIVGHSFGGAVALRIALDRPDLVSGLVLLAPVTHDWGEGSGTAWYNSIAANPVFG
CCCEEEEEEECCCCEEEEEEEECCCHHHCCEEEEEECCCCCCCCCCCEEEHHHCCCCCCH
PVFSQFVPIIGPSQMKDGISSVFAPAPTPQGYYQNSGLGLLLRPPNFRANAQDMTRLKDE
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHH
LAQQSARYGDLSVPITVFSGSKDTVLSPKLHAVRLKKQVPVEMVILPDEGHMPHHGEGSA
HHHHHCCCCCCEEEEEEEECCCCCEECCCHHEEEHHCCCCEEEEEECCCCCCCCCCCCHH
VAGAIRRLAFGRQTR
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MITVSLVALSGLGLGACVSSMAYTSKVEAAYPAEGRQIDVGGHDVHVLERGPGTAPVVLM
CEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEECCCCCCEEEEE
IHGASANAREFTGTLAPRLETDMRVLMADRPGHGYSERFDGAETLAAQARQMAGLLDQLA
EECCCCCCHHHHCCCCCCCCCCEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHC
PDQKAVIVGHSFGGAVALRIALDRPDLVSGLVLLAPVTHDWGEGSGTAWYNSIAANPVFG
CCCEEEEEEECCCCEEEEEEEECCCHHHCCEEEEEECCCCCCCCCCCEEEHHHCCCCCCH
PVFSQFVPIIGPSQMKDGISSVFAPAPTPQGYYQNSGLGLLLRPPNFRANAQDMTRLKDE
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHH
LAQQSARYGDLSVPITVFSGSKDTVLSPKLHAVRLKKQVPVEMVILPDEGHMPHHGEGSA
HHHHHCCCCCCEEEEEEEECCCCCEECCCHHEEEHHCCCCEEEEEECCCCCCCCCCCCHH
VAGAIRRLAFGRQTR
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]