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The map label for this gene is rpiA [H]

Identifier: 114798972

GI number: 114798972

Start: 717870

End: 718580

Strand: Direct

Name: rpiA [H]

Synonym: HNE_0706

Alternate gene names: 114798972

Gene position: 717870-718580 (Clockwise)

Preceding gene: 114797715

Following gene: 114799468

Centisome position: 19.38

GC content: 62.59

Gene sequence:

>711_bases
TTGCCGGACATGGCTAGCGACACCGAAAAGCAGAATGCGGCCGCCGCCGCGATGGACTTTGTTGAAGAGGGCATGACGAT
TGGCCTCGGCACCGGCTCAACGGCGAAATTCTTCGTCGAGATGCTGGCCGACGAGATCGCTGATGGCCTGATCGTGCGGT
GCATCGAAACCAGCAACCAGACGCGCGAACTGGCGCGCAGCCTCGGTGTGCCGCTGATCCCGTTCGAGCAGGTGGACCGT
ATCCATCTCACCGTTGATGGCGCCGATGAAGTCGGCCCCGGCGGCGTGCTGATCAAGGGCGGCGGCGCCGCGCTGCTGCG
CGAAAAGATCATCGCCAACGCCTCCGATCATATGGTCGTGATTGCCGACAGCTCGAAGGAAGTGCCCCATCTCGGCGCGT
TTCCGCTGCCGGTCGAAGTCACGCCGTTCGGCTACACGATTACGGCCAAGAAGGTGCATGACGCGCTGGTCGCCTCCGGC
GTGGAGCGCCCGCGTATCGAGCTGCGCAAGGCCGCCGGCAGCACTGATCTTCTGGTCACGGATGGCGGAAATCATATTCT
GGACTGCCATTGCGGCCGCATTCCAGACCCCGCCAAGACAGGTGCCTATCTCTCCGGTGTGCCCGGCGTTGTCGAGCATG
GCCTGTTCATCGGCATCGCCCGCACGGTGATCATCGGCGAGGAAAATGGCGCCCATATCATTGAATACTGA

Upstream 100 bases:

>100_bases
CGGCCAGCAGATCACCCGCGAGGGCTGGGCCAGGAACTACCGGGCAAAGAAGGCCGCAGAAAAGGCCGCCCGCACCACAG
ACCAGAACAAGAAGGGCTGA

Downstream 100 bases:

>100_bases
GGCGGGCGCCTCACATCTGTTGCCGATAACCCGCTGATACCCAAGGACCTTCCCATGACCGACACCGCCTACGACTATGA
CCTGTTCGTGATTGGCGGTG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MPDMASDTEKQNAAAAAMDFVEEGMTIGLGTGSTAKFFVEMLADEIADGLIVRCIETSNQTRELARSLGVPLIPFEQVDR
IHLTVDGADEVGPGGVLIKGGGAALLREKIIANASDHMVVIADSSKEVPHLGAFPLPVEVTPFGYTITAKKVHDALVASG
VERPRIELRKAAGSTDLLVTDGGNHILDCHCGRIPDPAKTGAYLSGVPGVVEHGLFIGIARTVIIGEENGAHIIEY

Sequences:

>Translated_236_residues
MPDMASDTEKQNAAAAAMDFVEEGMTIGLGTGSTAKFFVEMLADEIADGLIVRCIETSNQTRELARSLGVPLIPFEQVDR
IHLTVDGADEVGPGGVLIKGGGAALLREKIIANASDHMVVIADSSKEVPHLGAFPLPVEVTPFGYTITAKKVHDALVASG
VERPRIELRKAAGSTDLLVTDGGNHILDCHCGRIPDPAKTGAYLSGVPGVVEHGLFIGIARTVIIGEENGAHIIEY
>Mature_235_residues
PDMASDTEKQNAAAAAMDFVEEGMTIGLGTGSTAKFFVEMLADEIADGLIVRCIETSNQTRELARSLGVPLIPFEQVDRI
HLTVDGADEVGPGGVLIKGGGAALLREKIIANASDHMVVIADSSKEVPHLGAFPLPVEVTPFGYTITAKKVHDALVASGV
ERPRIELRKAAGSTDLLVTDGGNHILDCHCGRIPDPAKTGAYLSGVPGVVEHGLFIGIARTVIIGEENGAHIIEY

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=231, Percent_Identity=35.0649350649351, Blast_Score=122, Evalue=3e-28,
Organism=Escherichia coli, GI1789280, Length=232, Percent_Identity=40.0862068965517, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17551758, Length=232, Percent_Identity=33.1896551724138, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324669, Length=236, Percent_Identity=33.8983050847458, Blast_Score=108, Evalue=8e-25,
Organism=Drosophila melanogaster, GI281364072, Length=241, Percent_Identity=33.6099585062241, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24788; Mature: 24656

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDMASDTEKQNAAAAAMDFVEEGMTIGLGTGSTAKFFVEMLADEIADGLIVRCIETSNQ
CCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCH
TRELARSLGVPLIPFEQVDRIHLTVDGADEVGPGGVLIKGGGAALLREKIIANASDHMVV
HHHHHHHCCCCCCCHHHCCEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCEEE
IADSSKEVPHLGAFPLPVEVTPFGYTITAKKVHDALVASGVERPRIELRKAAGSTDLLVT
EECCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEE
DGGNHILDCHCGRIPDPAKTGAYLSGVPGVVEHGLFIGIARTVIIGEENGAHIIEY
CCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHEEEEEEEEEECCCCCEEECC
>Mature Secondary Structure 
PDMASDTEKQNAAAAAMDFVEEGMTIGLGTGSTAKFFVEMLADEIADGLIVRCIETSNQ
CCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCH
TRELARSLGVPLIPFEQVDRIHLTVDGADEVGPGGVLIKGGGAALLREKIIANASDHMVV
HHHHHHHCCCCCCCHHHCCEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCEEE
IADSSKEVPHLGAFPLPVEVTPFGYTITAKKVHDALVASGVERPRIELRKAAGSTDLLVT
EECCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEEE
DGGNHILDCHCGRIPDPAKTGAYLSGVPGVVEHGLFIGIARTVIIGEENGAHIIEY
CCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHEEEEEEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA