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The map label for this gene is yajO [H]

Identifier: 114798933

GI number: 114798933

Start: 2300264

End: 2301304

Strand: Reverse

Name: yajO [H]

Synonym: HNE_2204

Alternate gene names: 114798933

Gene position: 2301304-2300264 (Counterclockwise)

Preceding gene: 114799710

Following gene: 114798163

Centisome position: 62.11

GC content: 60.23

Gene sequence:

>1041_bases
ATGAAATATAAAACCCTTGGAAATACCGGCCTCTTTGTCTCCGAGATATGCTTGGGAACCATGACGTTTGGTGGCAAAGG
GCATTGGGCAAACATGGGCAACCTCCAGCAGGAGGACGCACAGAAACTGATTGCCCGCGCCCTGGAGCATGGCGTCAACT
TCATCGACACGGCCGATATCTATTCGGCCGGGGCCTCAGAGGAGATGGTGGGCCAGTCGCTCAGGAATCTGGGCGTCCGG
CGTGAGGATGTGGTAATTGCCACCAAGGTCTGCGGGCCTATGGGGGCAGGCCCCAATGATGCGGGCAATTCGCGGGGACA
TATTCTCGACAGCGTCAAGGCCAGCCTGAAACGGCTTCAGCTGGATCACATTGATCTCTACCAACTCCACAATATCGACA
CCGTCACGCCGGTCGAGGAGAGCCTTGCAGCGCTCGATACGCTCGTGCAGCAGGGGCTCGTCAGATATATTGGCGTTTCC
AACTGGTCTGCCTGGCAGATGGCGCGGGCGCTTGGCCATAGTGAGCGCCTGAAGCTCTCGCGATTTGCAACCACGCAGAA
TTATTACTCCCTGGTTGGCCGGGATATTGAGCGGGAGATTCTCCCCTTTGTGCAGGCTGAGAAGATGGGGCTTCTGGTCT
GGAGCCCGCTGGCGGGCGGATTGCTGGGCGGAAAATATGGGCGTGACCGGCAGGGCGAAGAAGGCAGCCGCCGGGCGCAT
TTCGACTTTCCTCCGGTCGACCGGGGCCAGGCCTGGAATGTGATTGATGTGCTCGACGAGATCGCGGAAGAGAAAGGCGT
ATCGGTGGCCAAGGTCGCGCTTGCGGCGCTTCTGCATCAGCCGCAGGTCACGAGTGTTATCGTTGGCGCCAAGCGGGTGT
CGCAGCTGGACGATTCTCTGGGCGCGACGGACGTCAGTCTCAGCCCGGACGAGATCGCCCGGCTGAATGCGGTCAGCGCG
CTTCCGCCTGCCTATCCGGCCTGGATGCAACGTGTACGGAAAGTTCCGCACCGGCCGGCGTCAGCGCCGACTTCAGACTA
A

Upstream 100 bases:

>100_bases
GATCAATGGCCAGGTCGTGTTTGCCAATGGCGGCTTCCTTTAAGGCCGGGTCTGGCAAAGGCCGGGAATTCTGCAGAGTG
TCCGTAACAGGAGAAAACCG

Downstream 100 bases:

>100_bases
GATCAGATTGATCGCGTTACGGTGTCTGACCGAATTTTCCTGAGCCCTGACGCCTGCACGAAGCCTGAAGGGCTATGTGA
CGTGCCCCCGTTCCCCGACG

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKYKTLGNTGLFVSEICLGTMTFGGKGHWANMGNLQQEDAQKLIARALEHGVNFIDTADIYSAGASEEMVGQSLRNLGVR
REDVVIATKVCGPMGAGPNDAGNSRGHILDSVKASLKRLQLDHIDLYQLHNIDTVTPVEESLAALDTLVQQGLVRYIGVS
NWSAWQMARALGHSERLKLSRFATTQNYYSLVGRDIEREILPFVQAEKMGLLVWSPLAGGLLGGKYGRDRQGEEGSRRAH
FDFPPVDRGQAWNVIDVLDEIAEEKGVSVAKVALAALLHQPQVTSVIVGAKRVSQLDDSLGATDVSLSPDEIARLNAVSA
LPPAYPAWMQRVRKVPHRPASAPTSD

Sequences:

>Translated_346_residues
MKYKTLGNTGLFVSEICLGTMTFGGKGHWANMGNLQQEDAQKLIARALEHGVNFIDTADIYSAGASEEMVGQSLRNLGVR
REDVVIATKVCGPMGAGPNDAGNSRGHILDSVKASLKRLQLDHIDLYQLHNIDTVTPVEESLAALDTLVQQGLVRYIGVS
NWSAWQMARALGHSERLKLSRFATTQNYYSLVGRDIEREILPFVQAEKMGLLVWSPLAGGLLGGKYGRDRQGEEGSRRAH
FDFPPVDRGQAWNVIDVLDEIAEEKGVSVAKVALAALLHQPQVTSVIVGAKRVSQLDDSLGATDVSLSPDEIARLNAVSA
LPPAYPAWMQRVRKVPHRPASAPTSD
>Mature_346_residues
MKYKTLGNTGLFVSEICLGTMTFGGKGHWANMGNLQQEDAQKLIARALEHGVNFIDTADIYSAGASEEMVGQSLRNLGVR
REDVVIATKVCGPMGAGPNDAGNSRGHILDSVKASLKRLQLDHIDLYQLHNIDTVTPVEESLAALDTLVQQGLVRYIGVS
NWSAWQMARALGHSERLKLSRFATTQNYYSLVGRDIEREILPFVQAEKMGLLVWSPLAGGLLGGKYGRDRQGEEGSRRAH
FDFPPVDRGQAWNVIDVLDEIAEEKGVSVAKVALAALLHQPQVTSVIVGAKRVSQLDDSLGATDVSLSPDEIARLNAVSA
LPPAYPAWMQRVRKVPHRPASAPTSD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=316, Percent_Identity=34.4936708860759, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI27436962, Length=316, Percent_Identity=34.1772151898734, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI27436969, Length=345, Percent_Identity=31.304347826087, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI4504825, Length=343, Percent_Identity=31.1953352769679, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI27436966, Length=316, Percent_Identity=33.8607594936709, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI27436971, Length=333, Percent_Identity=32.7327327327327, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI223718702, Length=293, Percent_Identity=30.7167235494881, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI41327764, Length=274, Percent_Identity=31.021897810219, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI41152114, Length=290, Percent_Identity=29.6551724137931, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI223718708, Length=141, Percent_Identity=38.2978723404255, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87081735, Length=316, Percent_Identity=41.4556962025316, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=31.1926605504587, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1789199, Length=357, Percent_Identity=33.6134453781513, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788070, Length=325, Percent_Identity=32.6153846153846, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788081, Length=310, Percent_Identity=30.3225806451613, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082198, Length=184, Percent_Identity=31.5217391304348, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994888, Length=298, Percent_Identity=27.5167785234899, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786400, Length=131, Percent_Identity=34.3511450381679, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=329, Percent_Identity=26.4437689969605, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17550248, Length=157, Percent_Identity=31.8471337579618, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=330, Percent_Identity=32.4242424242424, Blast_Score=169, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6323998, Length=326, Percent_Identity=29.4478527607362, Blast_Score=141, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=28.6184210526316, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6319951, Length=322, Percent_Identity=28.2608695652174, Blast_Score=122, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6322615, Length=255, Percent_Identity=27.843137254902, Blast_Score=112, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6321052, Length=153, Percent_Identity=33.9869281045752, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324694, Length=185, Percent_Identity=30.8108108108108, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24646155, Length=318, Percent_Identity=31.1320754716981, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI45549126, Length=324, Percent_Identity=28.3950617283951, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24640980, Length=324, Percent_Identity=28.3950617283951, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646159, Length=232, Percent_Identity=33.1896551724138, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24644950, Length=325, Percent_Identity=26.7692307692308, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37614; Mature: 37614

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYKTLGNTGLFVSEICLGTMTFGGKGHWANMGNLQQEDAQKLIARALEHGVNFIDTADI
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECHHH
YSAGASEEMVGQSLRNLGVRREDVVIATKVCGPMGAGPNDAGNSRGHILDSVKASLKRLQ
HHCCCCHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
LDHIDLYQLHNIDTVTPVEESLAALDTLVQQGLVRYIGVSNWSAWQMARALGHSERLKLS
CCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHH
RFATTQNYYSLVGRDIEREILPFVQAEKMGLLVWSPLAGGLLGGKYGRDRQGEEGSRRAH
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEECCHHCCHHCCCCCCCCCCCCCCCCCC
FDFPPVDRGQAWNVIDVLDEIAEEKGVSVAKVALAALLHQPQVTSVIVGAKRVSQLDDSL
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
GATDVSLSPDEIARLNAVSALPPAYPAWMQRVRKVPHRPASAPTSD
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKYKTLGNTGLFVSEICLGTMTFGGKGHWANMGNLQQEDAQKLIARALEHGVNFIDTADI
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECHHH
YSAGASEEMVGQSLRNLGVRREDVVIATKVCGPMGAGPNDAGNSRGHILDSVKASLKRLQ
HHCCCCHHHHHHHHHHCCCCCHHEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
LDHIDLYQLHNIDTVTPVEESLAALDTLVQQGLVRYIGVSNWSAWQMARALGHSERLKLS
CCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHH
RFATTQNYYSLVGRDIEREILPFVQAEKMGLLVWSPLAGGLLGGKYGRDRQGEEGSRRAH
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEECCHHCCHHCCCCCCCCCCCCCCCCCC
FDFPPVDRGQAWNVIDVLDEIAEEKGVSVAKVALAALLHQPQVTSVIVGAKRVSQLDDSL
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
GATDVSLSPDEIARLNAVSALPPAYPAWMQRVRKVPHRPASAPTSD
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]