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The map label for this gene is cry2 [H]

Identifier: 114798846

GI number: 114798846

Start: 3256990

End: 3258600

Strand: Direct

Name: cry2 [H]

Synonym: HNE_3082

Alternate gene names: 114798846

Gene position: 3256990-3258600 (Clockwise)

Preceding gene: 114798832

Following gene: 114797586

Centisome position: 87.91

GC content: 61.2

Gene sequence:

>1611_bases
TTGTTCTATATTTGTTCCATGTCTGGCGTGCATGTCATATGGTTCAAGCGGGATTTGCGTGTTCACGATCACGCAGCCTT
GGCGGCGGCGGTGGCGAGCGGCGCGCCTATCCTCCCGCTTTACATATTTGAGCCCGGTTATTGGGCGTTGCCCGAACATT
CCCGCCGTCAGTTCGATTTCGTCCGGGACTCTCTGGAAGAACTGGACGCCGCATTGAAAGCGCGCGGGACCAAGCTGGTA
ATCCGCATGGGGAGCGCGATTGATGTGTTTTCCGCGCTTCATCAGAAACACGGTATCGCGGCGATCCATGCCCATGAAGA
AACTGGCCTGCAATGGACCTTTGATCGCGACCGGGCGGTTCGGCGGTGGGCGCGGAATGCCGGCATTTCTCTGCGCGAAC
AGCCTCAGAATGGCGTTCAACGTGCCCTGCAATCACGCGACGGATGGGCCAATCAGTGGGAAGCTTTCATGCGCCGCCCC
AGACTGGTGGCCCCCGAGGCTTTAAAACCGTCGGCAGCAGACAGCGAGGAATGGCCTCTGCCGCAGGATTTTGGATTGGG
CGCGGATGACTGCCCTCAACGCCAGAAGGGTGGCCGGATGGCAGCCGTTGATTGCCTGCGTAGCTTTCTTGAAAGCCGGG
GCCGCACCTACCAGAAAAGCATGTCGAGCCCCCTGACGGCGGCCGATGCCTGCTCGCGCCTGTCGCCGCATTTGGCATTT
GGCACGGTCTCGATCAGAGAGGCCTGGCAGGCAGCGCAAAAAGCGCAGCACGAGCATGGCAGAAGCGGCGATACCGGATT
TGCCGCTTCGATCGGCAGCTTTATCTCCCGGCTGCAATGGCATTGCCATTTCATCCAGAAGCTTGAGGATCAGACATCCA
TAGAATCGCGCAATCTTCATCCCGGTTATGATGGCTTGCGCCCTGAACCCCTGGCGGGCGATCCCCGGCTTGCTGCCTGG
ATCGAGGGGCGTACCGGGTTTCCTTTCCTGGATGCCTGTATGCGCTCCCTCAGGGAGACAGGGTGGCTGAACTTCCGCAT
GCGCGCCATGGTTATGGGGTTTGCGTCACACCATCTCTGGCTCGATTGGAAACAACCGGCCGAACATCTGGCGGCCCTGT
TCACCGATTTTGAGCCTGGCATTCACTATCCCCAGGCACAGATGCAATCAGCGACGACCGGCATGAACACGCCCCGTATC
TATAATCCCGTCAAACAATCGCAGGACCAGGACCCGGATGGGGCGTTCATACGCCGCTGGGTTCCCGAACTTTCCGGGCT
ACCCGCCGAATGGCTGCACGCCCCCTGGGAAGCGCCCGCTTCGGTTCGCGCGCGAGCCGGAATCGTTCTGGGCCAGACCT
ATCCGATGCGGATTGTGGATCATATGGCAGCGGCCGAAGAGGCGCGTAGCCGGATATTTGCGGTGAGGAAGCGGGCCGGC
CATGGGGCCCAGGCAGACGCACTGCAGGCCCGCCACGGAAGTAAACGCTCCGGCATTCCCTTTCGCGGCCAGCAGGCTGC
GCGCAGGCAAGCGGTACCGAGGGCGCCGGAGCCGGCTCAGTTGAGCTTTGACCTCCACCTGACTCCGCCGTCGCAGGCCC
ATGCCTCATAG

Upstream 100 bases:

>100_bases
TTTCGCCATCGCAACGAGCTGATTGAATTTCCGGTCGTTTGGCAAAGTCGGCGCGGGGGCAATTTCACGCAGCACGCAAG
TCCCTTGCAAAAAGCGCCGT

Downstream 100 bases:

>100_bases
TCGCGCTCCGGGCAAAGCAACCGCCAAGAAAGATTTACCTTCGAAAACCTGCCCCACCTGCGGGCGCCCCTTCTCATGGC
GCAAGAAATGGGAACGGGTC

Product: deoxyribodipyrimidine photolyase family protein

Products: 2 pyrimidine residues (in DNA) [C]

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MFYICSMSGVHVIWFKRDLRVHDHAALAAAVASGAPILPLYIFEPGYWALPEHSRRQFDFVRDSLEELDAALKARGTKLV
IRMGSAIDVFSALHQKHGIAAIHAHEETGLQWTFDRDRAVRRWARNAGISLREQPQNGVQRALQSRDGWANQWEAFMRRP
RLVAPEALKPSAADSEEWPLPQDFGLGADDCPQRQKGGRMAAVDCLRSFLESRGRTYQKSMSSPLTAADACSRLSPHLAF
GTVSIREAWQAAQKAQHEHGRSGDTGFAASIGSFISRLQWHCHFIQKLEDQTSIESRNLHPGYDGLRPEPLAGDPRLAAW
IEGRTGFPFLDACMRSLRETGWLNFRMRAMVMGFASHHLWLDWKQPAEHLAALFTDFEPGIHYPQAQMQSATTGMNTPRI
YNPVKQSQDQDPDGAFIRRWVPELSGLPAEWLHAPWEAPASVRARAGIVLGQTYPMRIVDHMAAAEEARSRIFAVRKRAG
HGAQADALQARHGSKRSGIPFRGQQAARRQAVPRAPEPAQLSFDLHLTPPSQAHAS

Sequences:

>Translated_536_residues
MFYICSMSGVHVIWFKRDLRVHDHAALAAAVASGAPILPLYIFEPGYWALPEHSRRQFDFVRDSLEELDAALKARGTKLV
IRMGSAIDVFSALHQKHGIAAIHAHEETGLQWTFDRDRAVRRWARNAGISLREQPQNGVQRALQSRDGWANQWEAFMRRP
RLVAPEALKPSAADSEEWPLPQDFGLGADDCPQRQKGGRMAAVDCLRSFLESRGRTYQKSMSSPLTAADACSRLSPHLAF
GTVSIREAWQAAQKAQHEHGRSGDTGFAASIGSFISRLQWHCHFIQKLEDQTSIESRNLHPGYDGLRPEPLAGDPRLAAW
IEGRTGFPFLDACMRSLRETGWLNFRMRAMVMGFASHHLWLDWKQPAEHLAALFTDFEPGIHYPQAQMQSATTGMNTPRI
YNPVKQSQDQDPDGAFIRRWVPELSGLPAEWLHAPWEAPASVRARAGIVLGQTYPMRIVDHMAAAEEARSRIFAVRKRAG
HGAQADALQARHGSKRSGIPFRGQQAARRQAVPRAPEPAQLSFDLHLTPPSQAHAS
>Mature_536_residues
MFYICSMSGVHVIWFKRDLRVHDHAALAAAVASGAPILPLYIFEPGYWALPEHSRRQFDFVRDSLEELDAALKARGTKLV
IRMGSAIDVFSALHQKHGIAAIHAHEETGLQWTFDRDRAVRRWARNAGISLREQPQNGVQRALQSRDGWANQWEAFMRRP
RLVAPEALKPSAADSEEWPLPQDFGLGADDCPQRQKGGRMAAVDCLRSFLESRGRTYQKSMSSPLTAADACSRLSPHLAF
GTVSIREAWQAAQKAQHEHGRSGDTGFAASIGSFISRLQWHCHFIQKLEDQTSIESRNLHPGYDGLRPEPLAGDPRLAAW
IEGRTGFPFLDACMRSLRETGWLNFRMRAMVMGFASHHLWLDWKQPAEHLAALFTDFEPGIHYPQAQMQSATTGMNTPRI
YNPVKQSQDQDPDGAFIRRWVPELSGLPAEWLHAPWEAPASVRARAGIVLGQTYPMRIVDHMAAAEEARSRIFAVRKRAG
HGAQADALQARHGSKRSGIPFRGQQAARRQAVPRAPEPAQLSFDLHLTPPSQAHAS

Specific function: Has no photolyase activity [H]

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Homo sapiens, GI188536100, Length=505, Percent_Identity=25.7425742574257, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4758072, Length=493, Percent_Identity=24.7464503042596, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI188536103, Length=446, Percent_Identity=24.2152466367713, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1786926, Length=497, Percent_Identity=27.9678068410463, Blast_Score=148, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24648152, Length=510, Percent_Identity=25.0980392156863, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI17137248, Length=509, Percent_Identity=26.5225933202358, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24585455, Length=509, Percent_Identity=26.5225933202358, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: 4.1.99.3 [C]

Molecular weight: Translated: 59954; Mature: 59954

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYICSMSGVHVIWFKRDLRVHDHAALAAAVASGAPILPLYIFEPGYWALPEHSRRQFDF
CEEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHH
VRDSLEELDAALKARGTKLVIRMGSAIDVFSALHQKHGIAAIHAHEETGLQWTFDRDRAV
HHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCEEEEEECCCCCCEEEECHHHHH
RRWARNAGISLREQPQNGVQRALQSRDGWANQWEAFMRRPRLVAPEALKPSAADSEEWPL
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PQDFGLGADDCPQRQKGGRMAAVDCLRSFLESRGRTYQKSMSSPLTAADACSRLSPHLAF
CCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCCCEE
GTVSIREAWQAAQKAQHEHGRSGDTGFAASIGSFISRLQWHCHFIQKLEDQTSIESRNLH
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PGYDGLRPEPLAGDPRLAAWIEGRTGFPFLDACMRSLRETGWLNFRMRAMVMGFASHHLW
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEE
LDWKQPAEHLAALFTDFEPGIHYPQAQMQSATTGMNTPRIYNPVKQSQDQDPDGAFIRRW
EECHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHH
VPELSGLPAEWLHAPWEAPASVRARAGIVLGQTYPMRIVDHMAAAEEARSRIFAVRKRAG
HHHHCCCCHHHHCCCCCCCHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
HGAQADALQARHGSKRSGIPFRGQQAARRQAVPRAPEPAQLSFDLHLTPPSQAHAS
CCCCHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MFYICSMSGVHVIWFKRDLRVHDHAALAAAVASGAPILPLYIFEPGYWALPEHSRRQFDF
CEEEEECCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHH
VRDSLEELDAALKARGTKLVIRMGSAIDVFSALHQKHGIAAIHAHEETGLQWTFDRDRAV
HHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCEEEEEECCCCCCEEEECHHHHH
RRWARNAGISLREQPQNGVQRALQSRDGWANQWEAFMRRPRLVAPEALKPSAADSEEWPL
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PQDFGLGADDCPQRQKGGRMAAVDCLRSFLESRGRTYQKSMSSPLTAADACSRLSPHLAF
CCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCCCEE
GTVSIREAWQAAQKAQHEHGRSGDTGFAASIGSFISRLQWHCHFIQKLEDQTSIESRNLH
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PGYDGLRPEPLAGDPRLAAWIEGRTGFPFLDACMRSLRETGWLNFRMRAMVMGFASHHLW
CCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEE
LDWKQPAEHLAALFTDFEPGIHYPQAQMQSATTGMNTPRIYNPVKQSQDQDPDGAFIRRW
EECHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCCHHHHHHH
VPELSGLPAEWLHAPWEAPASVRARAGIVLGQTYPMRIVDHMAAAEEARSRIFAVRKRAG
HHHHCCCCHHHHCCCCCCCHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
HGAQADALQARHGSKRSGIPFRGQQAARRQAVPRAPEPAQLSFDLHLTPPSQAHAS
CCCCHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: ATP; FADH2; Flavin; pterin [C]

Metal ions: NA

Kcat value (1/min): 2.4 [C]

Specific activity: NA

Km value (mM): NA

Substrates: cyclobutadipyrimidine (in DNA) [C]

Specific reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA) [C]

General reaction: C-C-bond cleavage [C]

Inhibitor: yeast DNA [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]