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The map label for this gene is ywlC [H]

Identifier: 114798799

GI number: 114798799

Start: 1907192

End: 1908133

Strand: Direct

Name: ywlC [H]

Synonym: HNE_1848

Alternate gene names: 114798799

Gene position: 1907192-1908133 (Clockwise)

Preceding gene: 114799485

Following gene: 114799931

Centisome position: 51.48

GC content: 64.23

Gene sequence:

>942_bases
ATGTCCGCGCCCGTCGTCCCGATCCTGCCCGAAACTGTCGCCCTGGCGGTGGAAATCCTGAGCGGTGGCGGGCTTGTCGC
CATGCCGACGGAGACCGTCTACGGCCTTGCCGCGGATGCCGCCAACCCGGACGCCGTCGTCCGTCTGTACCAGGCCAAGG
GCCGTCCGCGCTTCAATCCGCTGATCGCTCACGTCTCAGGGACGGAAATGGCATCGCGGGAAGCGGTATTCTCGCCCCTG
GCAGAGCGTCTTGCCGAGAAATTCTGGCCAGGCCCGCTTACCCTTGTGTTACCGGTCAATCCGAATGGAACCGTCTGCGA
CCTTGCCCGCTCCGGCCTCCAGACAGTTGGCCTTCGCTGCCCCTCGCATCCCGCAGCCAACGCACTGATCACCGAATTCG
GCCGCCCCGTTGTCGCCCCTTCTGCCAATCGCTCCGGTCATGTAAGCCCAACGCGCGCAGAGCATGTTGCCGCCGACCTC
TCAGACCGGATTGATCTGATCCTGGATGGCGGTCCCTGCGATGTCGGGATCGAGTCAACAATCCTCGCGGTTGAGGGCGA
AACCGCAACGCTGTTGCGCTCAGGCGCAATTCCCAGCGACGTGCTCGAAACCTTCATCGGAAAATCTCTGGAACGGGCCA
GCGGATTGGCAATCTCGGCGCCCGGTATGCTCAAATCCCATTATGCGCCCAACGCGCAGCTCCGCCTCGACGCAGCCGCG
CCGGAAGCGGGAGAAGGGTATCTGGGGTTTGGCCCTGGCGTGCGCGAGGGGCTAAACCTCTCACCCGAGGGAGACCTCGC
AGAGGCCGCGACCAAGCTGTTTGCCATGCTGCGCGCGCTTGATGCACGGTTTGACCGCATCGCCATAGCCCCCATCCCGT
GGGAAGGGCTCGGCGAAGCTATCAACGACAGGCTGGCACGCGCGGCTTACCGCGACAATTGA

Upstream 100 bases:

>100_bases
CGCGGTTGAAGTCAAAGGCACGGCAACCCGCAACAACTGACGGGCGCCATCCGCGATGCTACGCATTGACGGCGATTAGC
CCAGTGCTAAGCGAGAAGCC

Downstream 100 bases:

>100_bases
TGAAGCAGCCTCAGCCGCCCATGATGTCTTCTTTAAGAACCGTCATCATGAACTGGTAAGAGGTCTCACCCTCATCTTCG
TCCTTGTAGACGACGGCGAT

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSAPVVPILPETVALAVEILSGGGLVAMPTETVYGLAADAANPDAVVRLYQAKGRPRFNPLIAHVSGTEMASREAVFSPL
AERLAEKFWPGPLTLVLPVNPNGTVCDLARSGLQTVGLRCPSHPAANALITEFGRPVVAPSANRSGHVSPTRAEHVAADL
SDRIDLILDGGPCDVGIESTILAVEGETATLLRSGAIPSDVLETFIGKSLERASGLAISAPGMLKSHYAPNAQLRLDAAA
PEAGEGYLGFGPGVREGLNLSPEGDLAEAATKLFAMLRALDARFDRIAIAPIPWEGLGEAINDRLARAAYRDN

Sequences:

>Translated_313_residues
MSAPVVPILPETVALAVEILSGGGLVAMPTETVYGLAADAANPDAVVRLYQAKGRPRFNPLIAHVSGTEMASREAVFSPL
AERLAEKFWPGPLTLVLPVNPNGTVCDLARSGLQTVGLRCPSHPAANALITEFGRPVVAPSANRSGHVSPTRAEHVAADL
SDRIDLILDGGPCDVGIESTILAVEGETATLLRSGAIPSDVLETFIGKSLERASGLAISAPGMLKSHYAPNAQLRLDAAA
PEAGEGYLGFGPGVREGLNLSPEGDLAEAATKLFAMLRALDARFDRIAIAPIPWEGLGEAINDRLARAAYRDN
>Mature_312_residues
SAPVVPILPETVALAVEILSGGGLVAMPTETVYGLAADAANPDAVVRLYQAKGRPRFNPLIAHVSGTEMASREAVFSPLA
ERLAEKFWPGPLTLVLPVNPNGTVCDLARSGLQTVGLRCPSHPAANALITEFGRPVVAPSANRSGHVSPTRAEHVAADLS
DRIDLILDGGPCDVGIESTILAVEGETATLLRSGAIPSDVLETFIGKSLERASGLAISAPGMLKSHYAPNAQLRLDAAAP
EAGEGYLGFGPGVREGLNLSPEGDLAEAATKLFAMLRALDARFDRIAIAPIPWEGLGEAINDRLARAAYRDN

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=148, Percent_Identity=29.7297297297297, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081864, Length=190, Percent_Identity=26.8421052631579, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537239, Length=202, Percent_Identity=32.1782178217822, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6321269, Length=305, Percent_Identity=37.0491803278689, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI78707274, Length=135, Percent_Identity=34.0740740740741, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 32646; Mature: 32514

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPVVPILPETVALAVEILSGGGLVAMPTETVYGLAADAANPDAVVRLYQAKGRPRFNP
CCCCCCCCCHHHHHHHHHHHCCCCEEEECCHHHHEEECCCCCHHHHEEEHHHCCCCCCCC
LIAHVSGTEMASREAVFSPLAERLAEKFWPGPLTLVLPVNPNGTVCDLARSGLQTVGLRC
EEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCHHHHCCCC
PSHPAANALITEFGRPVVAPSANRSGHVSPTRAEHVAADLSDRIDLILDGGPCDVGIEST
CCCCHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCE
ILAVEGETATLLRSGAIPSDVLETFIGKSLERASGLAISAPGMLKSHYAPNAQLRLDAAA
EEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCCEEEEECCC
PEAGEGYLGFGPGVREGLNLSPEGDLAEAATKLFAMLRALDARFDRIAIAPIPWEGLGEA
CCCCCCCEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHH
INDRLARAAYRDN
HHHHHHHHHHCCC
>Mature Secondary Structure 
SAPVVPILPETVALAVEILSGGGLVAMPTETVYGLAADAANPDAVVRLYQAKGRPRFNP
CCCCCCCCHHHHHHHHHHHCCCCEEEECCHHHHEEECCCCCHHHHEEEHHHCCCCCCCC
LIAHVSGTEMASREAVFSPLAERLAEKFWPGPLTLVLPVNPNGTVCDLARSGLQTVGLRC
EEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCHHHHCCCC
PSHPAANALITEFGRPVVAPSANRSGHVSPTRAEHVAADLSDRIDLILDGGPCDVGIEST
CCCCHHHHHHHHCCCCEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCE
ILAVEGETATLLRSGAIPSDVLETFIGKSLERASGLAISAPGMLKSHYAPNAQLRLDAAA
EEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCCEEEEECCC
PEAGEGYLGFGPGVREGLNLSPEGDLAEAATKLFAMLRALDARFDRIAIAPIPWEGLGEA
CCCCCCCEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHH
INDRLARAAYRDN
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]