Click here to switch to the map view.

The map label for this gene is czcC [H]

Identifier: 114798625

GI number: 114798625

Start: 1760096

End: 1761391

Strand: Reverse

Name: czcC [H]

Synonym: HNE_1716

Alternate gene names: 114798625

Gene position: 1761391-1760096 (Counterclockwise)

Preceding gene: 114797850

Following gene: 114800179

Centisome position: 47.54

GC content: 67.13

Gene sequence:

>1296_bases
ATGACATTCCTTTATCGGGGCGCGCTTGCCGCCCCGGCGTTCGCCCTCGCCGCATTCGTCGCGGCAGGCAGCGCCTCTGC
AAGCCCTTGCATGCCAGACCATGTTGCCGCGCCGAGCGCGCTCTCTCCAGATGTGCCCCTGACGCTTGAGGCGGCGCTCA
ATGAAATCCGCCGAACATCTCCGGATATACGGGCCGCCGGACTTGAAGCCCGCGCGCTCAATGCAGATGCGGACCAGGCC
GGCAGGTGGCTCAATCCAACGCTCACCGCAGATTTCGAGAACTTCTCCGGCGGCGGCGCCCTGTCCGGCTTCGACCAGTC
CGAGACAACATTCGGGGTCGAACAGACCTTCCGGCTGGGCAATAAGCGGGGCCTGGAAGAACGCGCAGCCCGCGCCCGGG
CGGCGCTGGGGACTGCTGAATGCGCTGTCATCCTTCGCGAATCCGAACGCGAGGCAGCGCTTGCGTATGCCGACCTGGTC
GCCGCGTCCGAAGCGGCAAGGCTCGCCGATGAGGCATCAAACCTCAGCTCAACCCTGGCAGAAACCGTCAGCAAAAGGGT
GGAGGCGGGCGCTGCGGCGCCTCCTGAGCTTGCCCGCGCCCGCGCAGACGCCGCGAGCCTACGTGCCGAAGCGGCGTTGG
CCCGGGGCGAAGTCGAGGCGAGGGCGTATGCGCTCGCAAGTCTCTGGGGCGAAGCCGATCTGCGTTTTGCCGTTCCCTCA
GAGTTCCAGATCATTGCCGCCGCCCAATCGGGTACGGCGCCTCATCCGAACCTGGCTGCCGCCAAGGCTGCGGTGGACGC
CAGAGAGGCCGAACTCAAGCGCGCCCGGGCTGAAGCTATTCCGGACGTCACACTTTCAGGTGGGGTCCGCCGGTTCGAAG
CGACAGGCGATAGCGCTTTCGTTGCCGGGCTGAGCTTGCCTCTGCCGCTGTTTGACCGCGGCAGCGATACCGTTCGGGCG
ACCCGTCTTCGCGGCGACGCCGCAAAGGTTTCTGCCGAAGCGGTCGAGGCGCGGCTCAGGGCCGAACAGGCGGCAGCCAC
CGCTACCGCCCGCGCGGCGAACACGAGGCTATCAATTCTCACCAAAGAGGCGCTGCCAGAGGCAGAAGCCGCATTCGAAG
CCGCTGACCAGGGTTACGCGATCGGCCGTTTCGACCTCACCACCACCCTCCAGGCGCGCGCGGCCCTGATCGACGTGCGC
CAGGCCACCATTGCCGCCCGCCGGGATGCGCGCGCGGCAGACCTTTTGCTCCGCAGCCTGATCGGCGCGGCCCCCTTTGA
CGGAGACACACAATGA

Upstream 100 bases:

>100_bases
TGCTGCGTCCGCCTCGGGCCTGATCCTCTGCAACCGTTTCCGGATGCGTCCTTCGCGTCCGGTGCCTGCCGAGACATCAG
CCTGAGGATCAAATCTTTCC

Downstream 100 bases:

>100_bases
TCGACCCCAAACTGACTGGGCTGGCACTGGTGCTGGCCATGACGCTCGCCGGCTGCGGCGGTTCCGGTGACACGGCCCGC
GCAGATGCTGCAGCGGTCGC

Product: efflux transporter, outer membrane factor

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTFLYRGALAAPAFALAAFVAAGSASASPCMPDHVAAPSALSPDVPLTLEAALNEIRRTSPDIRAAGLEARALNADADQA
GRWLNPTLTADFENFSGGGALSGFDQSETTFGVEQTFRLGNKRGLEERAARARAALGTAECAVILRESEREAALAYADLV
AASEAARLADEASNLSSTLAETVSKRVEAGAAAPPELARARADAASLRAEAALARGEVEARAYALASLWGEADLRFAVPS
EFQIIAAAQSGTAPHPNLAAAKAAVDAREAELKRARAEAIPDVTLSGGVRRFEATGDSAFVAGLSLPLPLFDRGSDTVRA
TRLRGDAAKVSAEAVEARLRAEQAAATATARAANTRLSILTKEALPEAEAAFEAADQGYAIGRFDLTTTLQARAALIDVR
QATIAARRDARAADLLLRSLIGAAPFDGDTQ

Sequences:

>Translated_431_residues
MTFLYRGALAAPAFALAAFVAAGSASASPCMPDHVAAPSALSPDVPLTLEAALNEIRRTSPDIRAAGLEARALNADADQA
GRWLNPTLTADFENFSGGGALSGFDQSETTFGVEQTFRLGNKRGLEERAARARAALGTAECAVILRESEREAALAYADLV
AASEAARLADEASNLSSTLAETVSKRVEAGAAAPPELARARADAASLRAEAALARGEVEARAYALASLWGEADLRFAVPS
EFQIIAAAQSGTAPHPNLAAAKAAVDAREAELKRARAEAIPDVTLSGGVRRFEATGDSAFVAGLSLPLPLFDRGSDTVRA
TRLRGDAAKVSAEAVEARLRAEQAAATATARAANTRLSILTKEALPEAEAAFEAADQGYAIGRFDLTTTLQARAALIDVR
QATIAARRDARAADLLLRSLIGAAPFDGDTQ
>Mature_430_residues
TFLYRGALAAPAFALAAFVAAGSASASPCMPDHVAAPSALSPDVPLTLEAALNEIRRTSPDIRAAGLEARALNADADQAG
RWLNPTLTADFENFSGGGALSGFDQSETTFGVEQTFRLGNKRGLEERAARARAALGTAECAVILRESEREAALAYADLVA
ASEAARLADEASNLSSTLAETVSKRVEAGAAAPPELARARADAASLRAEAALARGEVEARAYALASLWGEADLRFAVPSE
FQIIAAAQSGTAPHPNLAAAKAAVDAREAELKRARAEAIPDVTLSGGVRRFEATGDSAFVAGLSLPLPLFDRGSDTVRAT
RLRGDAAKVSAEAVEARLRAEQAAATATARAANTRLSILTKEALPEAEAAFEAADQGYAIGRFDLTTTLQARAALIDVRQ
ATIAARRDARAADLLLRSLIGAAPFDGDTQ

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 44678; Mature: 44547

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLYRGALAAPAFALAAFVAAGSASASPCMPDHVAAPSALSPDVPLTLEAALNEIRRTS
CCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCEEHHHHHHHHHHCC
PDIRAAGLEARALNADADQAGRWLNPTLTADFENFSGGGALSGFDQSETTFGVEQTFRLG
CCHHHCCCCCEECCCCHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCC
NKRGLEERAARARAALGTAECAVILRESEREAALAYADLVAASEAARLADEASNLSSTLA
CCCCHHHHHHHHHHHHCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETVSKRVEAGAAAPPELARARADAASLRAEAALARGEVEARAYALASLWGEADLRFAVPS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCC
EFQIIAAAQSGTAPHPNLAAAKAAVDAREAELKRARAEAIPDVTLSGGVRRFEATGDSAF
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEE
VAGLSLPLPLFDRGSDTVRATRLRGDAAKVSAEAVEARLRAEQAAATATARAANTRLSIL
EECCCCCCCCCCCCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEH
TKEALPEAEAAFEAADQGYAIGRFDLTTTLQARAALIDVRQATIAARRDARAADLLLRSL
HHHHCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IGAAPFDGDTQ
HCCCCCCCCCC
>Mature Secondary Structure 
TFLYRGALAAPAFALAAFVAAGSASASPCMPDHVAAPSALSPDVPLTLEAALNEIRRTS
CEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCEEHHHHHHHHHHCC
PDIRAAGLEARALNADADQAGRWLNPTLTADFENFSGGGALSGFDQSETTFGVEQTFRLG
CCHHHCCCCCEECCCCHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHCC
NKRGLEERAARARAALGTAECAVILRESEREAALAYADLVAASEAARLADEASNLSSTLA
CCCCHHHHHHHHHHHHCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ETVSKRVEAGAAAPPELARARADAASLRAEAALARGEVEARAYALASLWGEADLRFAVPS
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCC
EFQIIAAAQSGTAPHPNLAAAKAAVDAREAELKRARAEAIPDVTLSGGVRRFEATGDSAF
CEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEE
VAGLSLPLPLFDRGSDTVRATRLRGDAAKVSAEAVEARLRAEQAAATATARAANTRLSIL
EECCCCCCCCCCCCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEH
TKEALPEAEAAFEAADQGYAIGRFDLTTTLQARAALIDVRQATIAARRDARAADLLLRSL
HHHHCCHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IGAAPFDGDTQ
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]