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The map label for this gene is yngJ [H]

Identifier: 114798494

GI number: 114798494

Start: 828265

End: 829605

Strand: Direct

Name: yngJ [H]

Synonym: HNE_0809

Alternate gene names: 114798494

Gene position: 828265-829605 (Clockwise)

Preceding gene: 114800116

Following gene: 114799965

Centisome position: 22.36

GC content: 60.03

Gene sequence:

>1341_bases
ATGGATTTCAACATCCCACAGGACATCGCCGACTATCTGGTCGTGCTCGATAAATTCATCGAAGACGAAATCAAGCCACT
TCAGGCACAAGACGACAATGAGCGCTTCTTCGATCATCGCCGGGAATGGGCGCGGACTGACTTTGAAAATGAGGGCCTGC
CTCGCCCGGAATGGGAAGCGCTGCTGCGCGAAGCCAAGAAGCGCGCCGACAAGGCGGGCCACCTTCGCTATGCTCTCCCC
AAGGAATTTGGCGGCCAGGATGGCACCAATCTCGGCATGGCCATCATCCGCGAACATTTCGCCCGCCAGGGCCTTGGCCT
GCACAACGACCTGCAGAATGAGCACTCGATCGTGGGTAACTTCCCGCAGATCCTGATGCTGCGCGACTTTGCGCGGCCAG
ATCAGAAACACCTCGCCACGGCGGCGCTGGAAGGCAAGTTCATCGCCTGCTTCGGCCTGACCGAGCCCCATCACGGCTCT
GACGCGACGCATATGGAAACCCGCGCCGTGCGCCACAAGAAAGACGGCAAGGATGGCTGGCTGATCAATGGCGAGAAAAT
GTGGATCACCGGCATGCATGTGGCCACCCACATCATGCTGTTCTGCCGCACCAGCGGGAAAGATGGCGACGCGAAGGGCA
TCACCTGCCTGATCATCCCGGCGCGCGACCCTGGCGTGATCATTGAAGAGTATATGTGGACCTTCAACATGCCGACGGAC
CACCCGCGCCTCACCATCAAGGATGTGTGGGTGCCCGAAGACGCCGTGTTCGGCCCGCCCGAAGGCGGCCTGGCGCTCGC
CCAGCATTTCGTTCACGAAAACCGTATCCGTCAGGCCGCTTCCTCCTGCGGCGCGGCGCTCTACTGCATCAATGAGAGCG
TGAAGTATGCGCTCGAGCGCAAGCCCTTCGGCAAGCCGCTGGCCACCAACCAGGCCATCCAGTTCCCGCTGGTAGAGCTG
GCGACACAGGCTGAAATGCTCCGCCTTCTGATCTTCAAGACCGCTTGGGAAATGGACCAGATGTCCAAGCCGGAAGTGGC
GATCAAGCTCTCCGACAAGGTGTCGATGTGTAACTATTACGCCAACCGTCTTGTCTGCGAAGCAGCCGACCGGGCGATGC
AGGTGCATGGCGGCATTGGCTATTCGCGCCACAAGCCTTTCGAGCACATATACCGTCACCACCGCCGTTACCGGATCACC
GAAGGTTCCGAAGAGATCCAGATCCGCAAAGTGGCCGGCCACATGTTCGGCTTCATGGGCCCGAACAAGCACGGCCAGCC
CAAAGGCGAAACCGACGCAAAGGGCAAGAGCACAGAGCCGACGGATTTTGCGGTTCGGTAG

Upstream 100 bases:

>100_bases
CACATTCTCCCTGCGTCATTGCCCCGGCGGCACAAATTGCCGATGCGGCAGGCAGGGTTAAGGTGATCGGGAACCGCCGC
AGGAAACGAGGAAACCACCC

Downstream 100 bases:

>100_bases
ATCTGGAACTTCAAGCTCGATATGAAGAAAGCCGGGCTTTTCCAGCCCGGCTTTCTTTAAAGCCGCTCAAACGCCGCCGT
GAAGTGGCGCATCATCGGGG

Product: acyl-CoA dehydrogenase family protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MDFNIPQDIADYLVVLDKFIEDEIKPLQAQDDNERFFDHRREWARTDFENEGLPRPEWEALLREAKKRADKAGHLRYALP
KEFGGQDGTNLGMAIIREHFARQGLGLHNDLQNEHSIVGNFPQILMLRDFARPDQKHLATAALEGKFIACFGLTEPHHGS
DATHMETRAVRHKKDGKDGWLINGEKMWITGMHVATHIMLFCRTSGKDGDAKGITCLIIPARDPGVIIEEYMWTFNMPTD
HPRLTIKDVWVPEDAVFGPPEGGLALAQHFVHENRIRQAASSCGAALYCINESVKYALERKPFGKPLATNQAIQFPLVEL
ATQAEMLRLLIFKTAWEMDQMSKPEVAIKLSDKVSMCNYYANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYRIT
EGSEEIQIRKVAGHMFGFMGPNKHGQPKGETDAKGKSTEPTDFAVR

Sequences:

>Translated_446_residues
MDFNIPQDIADYLVVLDKFIEDEIKPLQAQDDNERFFDHRREWARTDFENEGLPRPEWEALLREAKKRADKAGHLRYALP
KEFGGQDGTNLGMAIIREHFARQGLGLHNDLQNEHSIVGNFPQILMLRDFARPDQKHLATAALEGKFIACFGLTEPHHGS
DATHMETRAVRHKKDGKDGWLINGEKMWITGMHVATHIMLFCRTSGKDGDAKGITCLIIPARDPGVIIEEYMWTFNMPTD
HPRLTIKDVWVPEDAVFGPPEGGLALAQHFVHENRIRQAASSCGAALYCINESVKYALERKPFGKPLATNQAIQFPLVEL
ATQAEMLRLLIFKTAWEMDQMSKPEVAIKLSDKVSMCNYYANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYRIT
EGSEEIQIRKVAGHMFGFMGPNKHGQPKGETDAKGKSTEPTDFAVR
>Mature_446_residues
MDFNIPQDIADYLVVLDKFIEDEIKPLQAQDDNERFFDHRREWARTDFENEGLPRPEWEALLREAKKRADKAGHLRYALP
KEFGGQDGTNLGMAIIREHFARQGLGLHNDLQNEHSIVGNFPQILMLRDFARPDQKHLATAALEGKFIACFGLTEPHHGS
DATHMETRAVRHKKDGKDGWLINGEKMWITGMHVATHIMLFCRTSGKDGDAKGITCLIIPARDPGVIIEEYMWTFNMPTD
HPRLTIKDVWVPEDAVFGPPEGGLALAQHFVHENRIRQAASSCGAALYCINESVKYALERKPFGKPLATNQAIQFPLVEL
ATQAEMLRLLIFKTAWEMDQMSKPEVAIKLSDKVSMCNYYANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYRIT
EGSEEIQIRKVAGHMFGFMGPNKHGQPKGETDAKGKSTEPTDFAVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=400, Percent_Identity=29, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI4557231, Length=415, Percent_Identity=28.433734939759, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI187960098, Length=415, Percent_Identity=28.433734939759, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI4501859, Length=404, Percent_Identity=26.4851485148515, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7656849, Length=284, Percent_Identity=31.3380281690141, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI21361497, Length=386, Percent_Identity=26.4248704663212, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4501857, Length=388, Percent_Identity=26.8041237113402, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI76496475, Length=396, Percent_Identity=25.2525252525253, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4557235, Length=396, Percent_Identity=25.2525252525253, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI7669494, Length=193, Percent_Identity=32.6424870466321, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4503943, Length=193, Percent_Identity=32.6424870466321, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI38505218, Length=278, Percent_Identity=26.2589928057554, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI48976061, Length=279, Percent_Identity=26.8817204301075, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI211971008, Length=279, Percent_Identity=26.8817204301075, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI226958412, Length=362, Percent_Identity=22.3756906077348, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI226958414, Length=361, Percent_Identity=21.8836565096953, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=28.1167108753316, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786223, Length=332, Percent_Identity=25.6024096385542, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081702, Length=269, Percent_Identity=26.0223048327138, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17534899, Length=374, Percent_Identity=31.283422459893, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI17570075, Length=428, Percent_Identity=27.3364485981308, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17569725, Length=363, Percent_Identity=29.7520661157025, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17506239, Length=405, Percent_Identity=25.1851851851852, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=343, Percent_Identity=26.8221574344023, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17533517, Length=264, Percent_Identity=30.3030303030303, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17505929, Length=347, Percent_Identity=28.2420749279539, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17551932, Length=304, Percent_Identity=27.3026315789474, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=341, Percent_Identity=28.4457478005865, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17534353, Length=322, Percent_Identity=26.0869565217391, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=277, Percent_Identity=27.4368231046931, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562446, Length=280, Percent_Identity=25.7142857142857, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17538396, Length=354, Percent_Identity=23.728813559322, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=323, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=242, Percent_Identity=26.8595041322314, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=183, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24660351, Length=427, Percent_Identity=30.2107728337237, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI24666513, Length=409, Percent_Identity=28.1173594132029, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24646207, Length=278, Percent_Identity=32.7338129496403, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356377, Length=346, Percent_Identity=28.9017341040462, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281363737, Length=388, Percent_Identity=28.0927835051546, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21355753, Length=409, Percent_Identity=24.2053789731051, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920834, Length=205, Percent_Identity=33.1707317073171, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 50706; Mature: 50706

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFNIPQDIADYLVVLDKFIEDEIKPLQAQDDNERFFDHRREWARTDFENEGLPRPEWEA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHH
LLREAKKRADKAGHLRYALPKEFGGQDGTNLGMAIIREHFARQGLGLHNDLQNEHSIVGN
HHHHHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCHHHHCC
FPQILMLRDFARPDQKHLATAALEGKFIACFGLTEPHHGSDATHMETRAVRHKKDGKDGW
CHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCC
LINGEKMWITGMHVATHIMLFCRTSGKDGDAKGITCLIIPARDPGVIIEEYMWTFNMPTD
EECCCEEEEEHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCCCCCHHHHHEEECCCCC
HPRLTIKDVWVPEDAVFGPPEGGLALAQHFVHENRIRQAASSCGAALYCINESVKYALER
CCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHC
KPFGKPLATNQAIQFPLVELATQAEMLRLLIFKTAWEMDQMSKPEVAIKLSDKVSMCNYY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHH
ANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYRITEGSEEIQIRKVAGHMFGFMG
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEECCCCCCEEHHHHHHHHHHCCC
PNKHGQPKGETDAKGKSTEPTDFAVR
CCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDFNIPQDIADYLVVLDKFIEDEIKPLQAQDDNERFFDHRREWARTDFENEGLPRPEWEA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHH
LLREAKKRADKAGHLRYALPKEFGGQDGTNLGMAIIREHFARQGLGLHNDLQNEHSIVGN
HHHHHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCHHHHCC
FPQILMLRDFARPDQKHLATAALEGKFIACFGLTEPHHGSDATHMETRAVRHKKDGKDGW
CHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCC
LINGEKMWITGMHVATHIMLFCRTSGKDGDAKGITCLIIPARDPGVIIEEYMWTFNMPTD
EECCCEEEEEHHHHHHHHHHHEECCCCCCCCCCEEEEEEECCCCCCCHHHHHEEECCCCC
HPRLTIKDVWVPEDAVFGPPEGGLALAQHFVHENRIRQAASSCGAALYCINESVKYALER
CCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHC
KPFGKPLATNQAIQFPLVELATQAEMLRLLIFKTAWEMDQMSKPEVAIKLSDKVSMCNYY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHH
ANRLVCEAADRAMQVHGGIGYSRHKPFEHIYRHHRRYRITEGSEEIQIRKVAGHMFGFMG
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEECCCCCCEEHHHHHHHHHHCCC
PNKHGQPKGETDAKGKSTEPTDFAVR
CCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]