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The map label for this gene is nudC [H]

Identifier: 114798474

GI number: 114798474

Start: 664382

End: 665299

Strand: Reverse

Name: nudC [H]

Synonym: HNE_0664

Alternate gene names: 114798474

Gene position: 665299-664382 (Counterclockwise)

Preceding gene: 114797087

Following gene: 114800259

Centisome position: 17.96

GC content: 59.26

Gene sequence:

>918_bases
ATGACGAACTCAAATGACATGCCCCTCGCCGCCAAGCCCATTAACCGCGCCGCCCATCGCCGCACCGATGAAGCCTGGCT
TGAAACCGCAATCCAGAACGACACCGCGCTGATCCTGATGCTGCGCGCAGGTGATCCGTTCGTAACGCCGGAAGGCGGTC
TCTACTGGTTTGGCCCGGAAGCCCTGCGCATATCACCGGGCAGCCCGCGCCTCTTTCTGGGTGAGGACAAGACCGGCGCG
CCCGTCTTTGCGATGGAGCTGCCCGCGAAGTTTGATCTTGCCGGTTCCCTGATCGCAGGCGCGGGCGAATTTCTCGACTT
CCGGCAGGCGTCTGCGCGTATGCCGGACATGGATGCCAACTGCGCGTCGACCGCCCGCAGTCTTTTCCTGTGGCATCAGA
GCCACAGCCACTGCGCAAAATGCGGCGGGCAGAATGGCATCGTCGAAGCCGGCTGGAAGGCGCAGTGCGCGATGTGCGGT
ACTGAACATTTTCCGCGTACCGATCCTGTTGCCATCATGCTTGCCGTGAAGGATGGCCGCGCACTGATCGGACGGCAGAA
GTTCTGGCCCGCAGGCTTCATGTCATGCCTGGCAGGCTTCTGCGAACCGGGCGAAACAATCGAGCAGGCAGCATCACGCG
AATTGTTTGAAGAAGCCGGAATCCACTGTGATCCCAGCAGAGCCGAGTATGTCGCCTGTCAACCATGGCCCTATCCTTCT
TCTCTCATGATGGGCTTTATTCTGCCTGCTGATTCCGATGAAATCACCATCGATCCAAACGAACTCGAGAGTGCGCGTTG
GGTTACGCGGGAAGAGATGCGCGACATTATCAATGGCAAGCATGCCGAACTCTTTTGCCCGCCGGCGACCGCGATTGCGC
ATCACATCATGAAGGTATGGGCCTTCAGAAACGATTGA

Upstream 100 bases:

>100_bases
TACCCCATGCGACTGCGGCAGAGTAGTGGCAGAGACGTGGCGAGGCTGGCGCTGCGTCCGGTGTTCCCTTCCCCGAAAAA
CCGATCTAGTCCTCTGACCC

Downstream 100 bases:

>100_bases
CCGTATACGGAATACTCCACAGATTCTCCTCATTTGTGAAAATCAGCAGTTGATTTCTCCCGAATCACGATATTATTGGC
TGGCCAGATGATAGGAGATC

Product: NUDIX family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTNSNDMPLAAKPINRAAHRRTDEAWLETAIQNDTALILMLRAGDPFVTPEGGLYWFGPEALRISPGSPRLFLGEDKTGA
PVFAMELPAKFDLAGSLIAGAGEFLDFRQASARMPDMDANCASTARSLFLWHQSHSHCAKCGGQNGIVEAGWKAQCAMCG
TEHFPRTDPVAIMLAVKDGRALIGRQKFWPAGFMSCLAGFCEPGETIEQAASRELFEEAGIHCDPSRAEYVACQPWPYPS
SLMMGFILPADSDEITIDPNELESARWVTREEMRDIINGKHAELFCPPATAIAHHIMKVWAFRND

Sequences:

>Translated_305_residues
MTNSNDMPLAAKPINRAAHRRTDEAWLETAIQNDTALILMLRAGDPFVTPEGGLYWFGPEALRISPGSPRLFLGEDKTGA
PVFAMELPAKFDLAGSLIAGAGEFLDFRQASARMPDMDANCASTARSLFLWHQSHSHCAKCGGQNGIVEAGWKAQCAMCG
TEHFPRTDPVAIMLAVKDGRALIGRQKFWPAGFMSCLAGFCEPGETIEQAASRELFEEAGIHCDPSRAEYVACQPWPYPS
SLMMGFILPADSDEITIDPNELESARWVTREEMRDIINGKHAELFCPPATAIAHHIMKVWAFRND
>Mature_304_residues
TNSNDMPLAAKPINRAAHRRTDEAWLETAIQNDTALILMLRAGDPFVTPEGGLYWFGPEALRISPGSPRLFLGEDKTGAP
VFAMELPAKFDLAGSLIAGAGEFLDFRQASARMPDMDANCASTARSLFLWHQSHSHCAKCGGQNGIVEAGWKAQCAMCGT
EHFPRTDPVAIMLAVKDGRALIGRQKFWPAGFMSCLAGFCEPGETIEQAASRELFEEAGIHCDPSRAEYVACQPWPYPSS
LMMGFILPADSDEITIDPNELESARWVTREEMRDIINGKHAELFCPPATAIAHHIMKVWAFRND

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=339, Percent_Identity=32.4483775811209, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI50593112, Length=266, Percent_Identity=30.8270676691729, Blast_Score=126, Evalue=2e-29,
Organism=Escherichia coli, GI48994995, Length=207, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71986510, Length=221, Percent_Identity=30.316742081448, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI212645999, Length=221, Percent_Identity=30.316742081448, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321371, Length=188, Percent_Identity=35.1063829787234, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 33528; Mature: 33396

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSNDMPLAAKPINRAAHRRTDEAWLETAIQNDTALILMLRAGDPFVTPEGGLYWFGPE
CCCCCCCCEECCHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCEECCCCCEEEECCC
ALRISPGSPRLFLGEDKTGAPVFAMELPAKFDLAGSLIAGAGEFLDFRQASARMPDMDAN
EEEECCCCCEEEECCCCCCCCEEEEECCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCH
CASTARSLFLWHQSHSHCAKCGGQNGIVEAGWKAQCAMCGTEHFPRTDPVAIMLAVKDGR
HHHHHHHHEEEECCCHHHHHCCCCCCEEECCCCCEEEECCCCCCCCCCCEEEEEEEECCC
ALIGRQKFWPAGFMSCLAGFCEPGETIEQAASRELFEEAGIHCDPSRAEYVACQPWPYPS
EECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCH
SLMMGFILPADSDEITIDPNELESARWVTREEMRDIINGKHAELFCPPATAIAHHIMKVW
HHHEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
AFRND
HHCCC
>Mature Secondary Structure 
TNSNDMPLAAKPINRAAHRRTDEAWLETAIQNDTALILMLRAGDPFVTPEGGLYWFGPE
CCCCCCCEECCHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCEECCCCCEEEECCC
ALRISPGSPRLFLGEDKTGAPVFAMELPAKFDLAGSLIAGAGEFLDFRQASARMPDMDAN
EEEECCCCCEEEECCCCCCCCEEEEECCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCH
CASTARSLFLWHQSHSHCAKCGGQNGIVEAGWKAQCAMCGTEHFPRTDPVAIMLAVKDGR
HHHHHHHHEEEECCCHHHHHCCCCCCEEECCCCCEEEECCCCCCCCCCCEEEEEEEECCC
ALIGRQKFWPAGFMSCLAGFCEPGETIEQAASRELFEEAGIHCDPSRAEYVACQPWPYPS
EECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCH
SLMMGFILPADSDEITIDPNELESARWVTREEMRDIINGKHAELFCPPATAIAHHIMKVW
HHHEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHH
AFRND
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]