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The map label for this gene is yngJ [H]

Identifier: 114798453

GI number: 114798453

Start: 2957024

End: 2958250

Strand: Direct

Name: yngJ [H]

Synonym: HNE_2795

Alternate gene names: 114798453

Gene position: 2957024-2958250 (Clockwise)

Preceding gene: 114799652

Following gene: 114797612

Centisome position: 79.81

GC content: 61.04

Gene sequence:

>1227_bases
ATGCAGTTCGATCACAGCCCGAAAACGCAAGACCTCATCAACCGCCTCGAAGCCTTCTTCGACAAGCATGTCTACCCGAC
CGAGCAGGACCATTACGACTGGAACCATAATCCGGCAAATCTCTGGAAGCGCTGGCCCGGCATCGACAAGATCAAGGAAC
ACGCCAAGGCCGAAGGCCTGTGGAACCTCTTCTTGCCGCATGAGTATGGCGAGTTCAGCCCCGGCCTGACCAATCTGGAA
TATGCCCCGCTGGCGGAAATCATGGGCCGCGTGCCCCACTCTTCAGAATTCTTCAACTGCTCGGCGCCCGACACCGGCAA
TATGGAAGTCCTCGCCAAGTTCGGCTCTCCGGCCCAGCAGGAGCGCTGGCTGAAGCCGCTTCTGGCCGGCGAAATCCGCT
CAGCCTATGTGATGACAGAGCCGCAGGTTGCCTCCTCCGACGCCACCAATCTGGAACTCACCATCCTTCCGGATGGGGAC
GATTACGTCATCAATGGCCGCAAATGGTGGATCTCCGGCGCGATGAACCCCAATTGCAAGATCTGGATCGTCATGGGCAA
GACCCTGCTGGATAATCCGCGCCATCAGCAGCATTCGCAAATCCTGGTCGAGCCCGGCACGCCCGGCATCACCATCGTGC
GCAACCAGACCGTCTTCGGCTCTCACAATTCCCCCGGCGGCGAGTGCGAGCTGCGCTTTGAAAATGTCCGCGTGCCCAAG
GAAAACCTCATCCTCGGCGAAGGCCGCGGCTTTGAAATTGCCCAGGGCCGCCTCGGCCCCGGCCGCATCCACCATTGCAT
GCGCTCCATCGGCCAGGCCCAGCGCGCGCTGGAAATCATGTCGCGCCGCGTCGAAAACCGCGTCGCCTTCGGCAAGAAGA
TTTCCGATCAGTCCTCCATCCGCCAGGATGTCGCCAAGAGCTTCTGCGAAATCGAGATGGCCCGCCTGCTTACCCTGAAG
GCCGCCGACGCGATGGACCGCCATGGCAACAAGGGCGCCAAGGATCTCATCGCCGCCATCAAGGTCATCGCGCCGCAAAT
GGCCCAGACCGTGTGCGACCGTGCCATCCAGGCCCATGGCGGCATGGGCGTCAGCGACGACACCCCCATCGCCAGCTTCT
TCACCCTCAACCGTTTCCTGCGCATCGCAGATGGTCCGGACGAAGTCCACATGTCCCAGCTCGGCAAGCTGAAAATCCAG
GAATATAACGCCCTTCCGGTCCGCTGA

Upstream 100 bases:

>100_bases
GATCTCCACCGCCGCACCATCTGGCTGCTCGAACGCGCCCTGCGCTGGATCAGCTAAGCCTCCTCAAGACACGCGAAACA
CAAAAAACAGGAACACCCTC

Downstream 100 bases:

>100_bases
TCTGTCCGCTCAAGGAGAAACGCCATGAAAGCTCTCGTTTATCGCGGCCCGCGCGACATCGCCTTTGAAACGATGAAAGA
CCCCGACCTGCACGATGACC

Product: putative acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MQFDHSPKTQDLINRLEAFFDKHVYPTEQDHYDWNHNPANLWKRWPGIDKIKEHAKAEGLWNLFLPHEYGEFSPGLTNLE
YAPLAEIMGRVPHSSEFFNCSAPDTGNMEVLAKFGSPAQQERWLKPLLAGEIRSAYVMTEPQVASSDATNLELTILPDGD
DYVINGRKWWISGAMNPNCKIWIVMGKTLLDNPRHQQHSQILVEPGTPGITIVRNQTVFGSHNSPGGECELRFENVRVPK
ENLILGEGRGFEIAQGRLGPGRIHHCMRSIGQAQRALEIMSRRVENRVAFGKKISDQSSIRQDVAKSFCEIEMARLLTLK
AADAMDRHGNKGAKDLIAAIKVIAPQMAQTVCDRAIQAHGGMGVSDDTPIASFFTLNRFLRIADGPDEVHMSQLGKLKIQ
EYNALPVR

Sequences:

>Translated_408_residues
MQFDHSPKTQDLINRLEAFFDKHVYPTEQDHYDWNHNPANLWKRWPGIDKIKEHAKAEGLWNLFLPHEYGEFSPGLTNLE
YAPLAEIMGRVPHSSEFFNCSAPDTGNMEVLAKFGSPAQQERWLKPLLAGEIRSAYVMTEPQVASSDATNLELTILPDGD
DYVINGRKWWISGAMNPNCKIWIVMGKTLLDNPRHQQHSQILVEPGTPGITIVRNQTVFGSHNSPGGECELRFENVRVPK
ENLILGEGRGFEIAQGRLGPGRIHHCMRSIGQAQRALEIMSRRVENRVAFGKKISDQSSIRQDVAKSFCEIEMARLLTLK
AADAMDRHGNKGAKDLIAAIKVIAPQMAQTVCDRAIQAHGGMGVSDDTPIASFFTLNRFLRIADGPDEVHMSQLGKLKIQ
EYNALPVR
>Mature_408_residues
MQFDHSPKTQDLINRLEAFFDKHVYPTEQDHYDWNHNPANLWKRWPGIDKIKEHAKAEGLWNLFLPHEYGEFSPGLTNLE
YAPLAEIMGRVPHSSEFFNCSAPDTGNMEVLAKFGSPAQQERWLKPLLAGEIRSAYVMTEPQVASSDATNLELTILPDGD
DYVINGRKWWISGAMNPNCKIWIVMGKTLLDNPRHQQHSQILVEPGTPGITIVRNQTVFGSHNSPGGECELRFENVRVPK
ENLILGEGRGFEIAQGRLGPGRIHHCMRSIGQAQRALEIMSRRVENRVAFGKKISDQSSIRQDVAKSFCEIEMARLLTLK
AADAMDRHGNKGAKDLIAAIKVIAPQMAQTVCDRAIQAHGGMGVSDDTPIASFFTLNRFLRIADGPDEVHMSQLGKLKIQ
EYNALPVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI48976061, Length=398, Percent_Identity=55.0251256281407, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI211971008, Length=398, Percent_Identity=55.0251256281407, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI38505218, Length=404, Percent_Identity=51.2376237623762, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI4557233, Length=386, Percent_Identity=30.3108808290155, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI4501859, Length=347, Percent_Identity=28.8184438040346, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI226958412, Length=394, Percent_Identity=26.6497461928934, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI7656849, Length=292, Percent_Identity=30.1369863013699, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI4557231, Length=410, Percent_Identity=24.1463414634146, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI187960098, Length=410, Percent_Identity=24.1463414634146, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI21361497, Length=347, Percent_Identity=28.5302593659942, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI4557235, Length=391, Percent_Identity=28.3887468030691, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI76496475, Length=391, Percent_Identity=28.3887468030691, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=27.8592375366569, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4501857, Length=299, Percent_Identity=26.0869565217391, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI87081958, Length=315, Percent_Identity=27.6190476190476, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786223, Length=345, Percent_Identity=24.3478260869565, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=365, Percent_Identity=52.3287671232877, Blast_Score=388, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=28.0653950953678, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17538396, Length=348, Percent_Identity=28.1609195402299, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71985184, Length=340, Percent_Identity=29.7058823529412, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17569725, Length=350, Percent_Identity=28, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17508101, Length=347, Percent_Identity=27.0893371757925, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17506239, Length=403, Percent_Identity=25.0620347394541, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=280, Percent_Identity=29.2857142857143, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=32.1167883211679, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17570075, Length=275, Percent_Identity=26.9090909090909, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=334, Percent_Identity=26.6467065868263, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71985192, Length=275, Percent_Identity=26.9090909090909, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=342, Percent_Identity=26.9005847953216, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI32563615, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=345, Percent_Identity=30.4347826086957, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281363737, Length=392, Percent_Identity=29.3367346938776, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24666513, Length=295, Percent_Identity=30.5084745762712, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24646207, Length=332, Percent_Identity=29.5180722891566, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24660351, Length=278, Percent_Identity=29.4964028776978, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21355753, Length=293, Percent_Identity=26.962457337884, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 45780; Mature: 45780

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDHSPKTQDLINRLEAFFDKHVYPTEQDHYDWNHNPANLWKRWPGIDKIKEHAKAEGL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCE
WNLFLPHEYGEFSPGLTNLEYAPLAEIMGRVPHSSEFFNCSAPDTGNMEVLAKFGSPAQQ
EEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEECCCCCCCCHHEEEECCCCHHH
ERWLKPLLAGEIRSAYVMTEPQVASSDATNLELTILPDGDDYVINGRKWWISGAMNPNCK
HHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEEECCCCEEECCEEEEEECCCCCCCE
IWIVMGKTLLDNPRHQQHSQILVEPGTPGITIVRNQTVFGSHNSPGGECELRFENVRVPK
EEEEECHHHHCCCCCCCCCEEEEECCCCCEEEEECCEEECCCCCCCCEEEEEEECCCCCH
ENLILGEGRGFEIAQGRLGPGRIHHCMRSIGQAQRALEIMSRRVENRVAFGKKISDQSSI
HHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RQDVAKSFCEIEMARLLTLKAADAMDRHGNKGAKDLIAAIKVIAPQMAQTVCDRAIQAHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMGVSDDTPIASFFTLNRFLRIADGPDEVHMSQLGKLKIQEYNALPVR
CCCCCCCCCHHHHHHHHHHHEECCCCCHHHHHHHCCEEEEECCCCCCC
>Mature Secondary Structure
MQFDHSPKTQDLINRLEAFFDKHVYPTEQDHYDWNHNPANLWKRWPGIDKIKEHAKAEGL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCE
WNLFLPHEYGEFSPGLTNLEYAPLAEIMGRVPHSSEFFNCSAPDTGNMEVLAKFGSPAQQ
EEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEECCCCCCCCHHEEEECCCCHHH
ERWLKPLLAGEIRSAYVMTEPQVASSDATNLELTILPDGDDYVINGRKWWISGAMNPNCK
HHHHHHHHHHHHHHEEEEECCCCCCCCCCCEEEEEEECCCCEEECCEEEEEECCCCCCCE
IWIVMGKTLLDNPRHQQHSQILVEPGTPGITIVRNQTVFGSHNSPGGECELRFENVRVPK
EEEEECHHHHCCCCCCCCCEEEEECCCCCEEEEECCEEECCCCCCCCEEEEEEECCCCCH
ENLILGEGRGFEIAQGRLGPGRIHHCMRSIGQAQRALEIMSRRVENRVAFGKKISDQSSI
HHEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RQDVAKSFCEIEMARLLTLKAADAMDRHGNKGAKDLIAAIKVIAPQMAQTVCDRAIQAHG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMGVSDDTPIASFFTLNRFLRIADGPDEVHMSQLGKLKIQEYNALPVR
CCCCCCCCCHHHHHHHHHHHEECCCCCHHHHHHHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]