The gene/protein map for NC_008358 is currently unavailable.
Definition Hyphomonas neptunium ATCC 15444 chromosome, complete genome.
Accession NC_008358
Length 3,705,021

Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 114798063

GI number: 114798063

Start: 2150188

End: 2150925

Strand: Direct

Name: fabG [H]

Synonym: HNE_2076

Alternate gene names: 114798063

Gene position: 2150188-2150925 (Clockwise)

Preceding gene: 114797975

Following gene: 114797560

Centisome position: 58.03

GC content: 60.98

Gene sequence:

>738_bases
ATGCGTCACGTTATCGTCACCGGCGGCAGCCGGGGACTGGGCGCCGCCATGATCGACGGACTGCTTGCCGATGGCTACCG
GGTCTCGACCTGCTCGCGCTCCAAATCCCCAAACATCGAAGCCCTGATGGCCCATCCCGAGTATGGATCGCGGTTTTTCT
GGCAGCGCTGTGAAGTGGGGGAAGCCGATCAGGTGGATGCGTTTGTGGACGCGGCCGTTGAATGGGCCGGAGAAGATGGC
CTGTGGGGTCTCGTCAATAATGCCGGCGTCGCGCAGACGGGCATTCTCGCGTCTTTCCCAAATCGCGAGACCGAGAAAAT
CATTAAGGTGAACCTGTTTGGTGCCATCCAGGCCGCGCGGGCCGCTTCCGAGCATATGCTGCGCGCCAATAAAGGCGGGC
GGATCATCAATATCTCATCCATTATCGGCAGCCGGGGCTATAACGGCATGACGGCCTATTCAGCCTCCAAGGCCGGCATG
GACGGCCTGACGCGCGCACTGGCGCGAGAGTTGGGCCGCCGGAAAATCACCGTCAATTCGGTCGCGCCGGGTTATGTGCT
GACAGAGATGTCGTCCGTACTCACACCGGTTCAGCTCAACCAGATTGTGAACCGCACGCCGCTCGGCATGCTGGCGGATG
ATGAGGACGTTACCAATCTGGTGCGCTTCCTGCTGTCGGATGGCGCGCGGATGATCACCGGCCAGACAATCCTGGTTGAT
GGCGGCGTTTCCTGCTGA

Upstream 100 bases:

>100_bases
ATCAGGTTCCGCGCGCCTTCAAGGTGGTTGACGCCATCGCTGTGCGTGAATCTGGCAAGAAAGGCTAATACGCATGACCG
CGCCCGCAGCTTCTTCCCAA

Downstream 100 bases:

>100_bases
TTACCCTTCCCGATTGCTGACCTGCTTTGCCCGCAAAAGGGCGAGCATTCCCAGGATGATCAGTGCGCCCCACAGCCAGT
GGGATGCCACGAAATTGGAC

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MRHVIVTGGSRGLGAAMIDGLLADGYRVSTCSRSKSPNIEALMAHPEYGSRFFWQRCEVGEADQVDAFVDAAVEWAGEDG
LWGLVNNAGVAQTGILASFPNRETEKIIKVNLFGAIQAARAASEHMLRANKGGRIINISSIIGSRGYNGMTAYSASKAGM
DGLTRALARELGRRKITVNSVAPGYVLTEMSSVLTPVQLNQIVNRTPLGMLADDEDVTNLVRFLLSDGARMITGQTILVD
GGVSC

Sequences:

>Translated_245_residues
MRHVIVTGGSRGLGAAMIDGLLADGYRVSTCSRSKSPNIEALMAHPEYGSRFFWQRCEVGEADQVDAFVDAAVEWAGEDG
LWGLVNNAGVAQTGILASFPNRETEKIIKVNLFGAIQAARAASEHMLRANKGGRIINISSIIGSRGYNGMTAYSASKAGM
DGLTRALARELGRRKITVNSVAPGYVLTEMSSVLTPVQLNQIVNRTPLGMLADDEDVTNLVRFLLSDGARMITGQTILVD
GGVSC
>Mature_245_residues
MRHVIVTGGSRGLGAAMIDGLLADGYRVSTCSRSKSPNIEALMAHPEYGSRFFWQRCEVGEADQVDAFVDAAVEWAGEDG
LWGLVNNAGVAQTGILASFPNRETEKIIKVNLFGAIQAARAASEHMLRANKGGRIINISSIIGSRGYNGMTAYSASKAGM
DGLTRALARELGRRKITVNSVAPGYVLTEMSSVLTPVQLNQIVNRTPLGMLADDEDVTNLVRFLLSDGARMITGQTILVD
GGVSC

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=240, Percent_Identity=35, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI15277342, Length=247, Percent_Identity=34.0080971659919, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=31.8897637795276, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=30.7053941908714, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=28.125, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=31.1475409836066, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI19743808, Length=194, Percent_Identity=31.4432989690722, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4503301, Length=193, Percent_Identity=28.4974093264249, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI150247226, Length=197, Percent_Identity=30.9644670050761, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=31.413612565445, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI109715829, Length=242, Percent_Identity=29.3388429752066, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=29.7959183673469, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=32.8205128205128, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI66933014, Length=216, Percent_Identity=27.3148148148148, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4503817, Length=229, Percent_Identity=27.5109170305677, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI44680136, Length=129, Percent_Identity=31.0077519379845, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI44680133, Length=129, Percent_Identity=31.0077519379845, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI17738292, Length=129, Percent_Identity=31.0077519379845, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI4504505, Length=116, Percent_Identity=37.9310344827586, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=34.5833333333333, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=31.1203319502075, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=30.241935483871, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1788459, Length=159, Percent_Identity=37.1069182389937, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=33.596837944664, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=29.6296296296296, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=30.6451612903226, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082100, Length=219, Percent_Identity=35.1598173515982, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=28.099173553719, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=30.2904564315353, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=27.4900398406374, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787891, Length=244, Percent_Identity=25.4098360655738, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786701, Length=203, Percent_Identity=27.0935960591133, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=33.1967213114754, Blast_Score=121, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=33.0612244897959, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=31.7991631799163, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=31.7269076305221, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=30.1204819277108, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=26.5873015873016, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=27.0676691729323, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=29.0566037735849, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=28.6764705882353, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=27.9693486590038, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=258, Percent_Identity=29.4573643410853, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=28.0898876404494, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=27.3764258555133, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193207185, Length=148, Percent_Identity=32.4324324324324, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=27.1317829457364, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=28.5171102661597, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=28.6245353159851, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=24.907063197026, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=27.4436090225564, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=178, Percent_Identity=31.4606741573034, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=251, Percent_Identity=29.0836653386454, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=27.2030651340996, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=24.904214559387, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=182, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320089, Length=203, Percent_Identity=30.0492610837438, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=119, Percent_Identity=39.4957983193277, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=192, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24643142, Length=251, Percent_Identity=33.0677290836653, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=29.9595141700405, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=31.8548387096774, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=31.0483870967742, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI28571387, Length=237, Percent_Identity=30.379746835443, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=29.0836653386454, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=28.5140562248996, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=27.3809523809524, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI116007236, Length=233, Percent_Identity=28.3261802575107, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24644337, Length=165, Percent_Identity=30.9090909090909, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641388, Length=200, Percent_Identity=31, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364494, Length=197, Percent_Identity=30.4568527918782, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=27.8350515463918, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640547, Length=219, Percent_Identity=29.2237442922374, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI116007234, Length=200, Percent_Identity=30.5, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26105; Mature: 26105

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MRHVIVTGGSRGLGAAMIDGLLADGYRVSTCSRSKSPNIEALMAHPEYGSRFFWQRCEVG
CCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHCCCC
EADQVDAFVDAAVEWAGEDGLWGLVNNAGVAQTGILASFPNRETEKIIKVNLFGAIQAAR
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHCCEECCCCCCCCEEEEEEHHHHHHHHH
AASEHMLRANKGGRIINISSIIGSRGYNGMTAYSASKAGMDGLTRALARELGRRKITVNS
HHHHHHHHHCCCCCEEEEHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCEEEECC
VAPGYVLTEMSSVLTPVQLNQIVNRTPLGMLADDEDVTNLVRFLLSDGARMITGQTILVD
CCCCHHHHHHHHHHCHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCEEEECCEEEEC
GGVSC
CCCCC
>Mature Secondary Structure
MRHVIVTGGSRGLGAAMIDGLLADGYRVSTCSRSKSPNIEALMAHPEYGSRFFWQRCEVG
CCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCHHHHHHCCCC
EADQVDAFVDAAVEWAGEDGLWGLVNNAGVAQTGILASFPNRETEKIIKVNLFGAIQAAR
CCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHCCEECCCCCCCCEEEEEEHHHHHHHHH
AASEHMLRANKGGRIINISSIIGSRGYNGMTAYSASKAGMDGLTRALARELGRRKITVNS
HHHHHHHHHCCCCCEEEEHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCEEEECC
VAPGYVLTEMSSVLTPVQLNQIVNRTPLGMLADDEDVTNLVRFLLSDGARMITGQTILVD
CCCCHHHHHHHHHHCHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCEEEECCEEEEC
GGVSC
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA