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The map label for this gene is yajO [H]

Identifier: 114798006

GI number: 114798006

Start: 1401263

End: 1402297

Strand: Reverse

Name: yajO [H]

Synonym: HNE_1371

Alternate gene names: 114798006

Gene position: 1402297-1401263 (Counterclockwise)

Preceding gene: 114800381

Following gene: 114797331

Centisome position: 37.85

GC content: 62.22

Gene sequence:

>1035_bases
ATGGACTTCAGACAATTGGGCGCGTCCGGGCTCCGGGTTCCGGCACTGAGTTTTGGCGCAGGCACTTTCGGGGGGAAAGG
CCCCCTGTTCGGCGCTTGGGGAACCAACGACACTGACGCCGCACGCCGCTTGGTGGACATCTGCCTCGATGCCGGGGTCA
ACCTGTTTGATACGGCAGACGTCTATTCAGATGGCGCATCGGAGGAAGTTCTCGGTGCGGCAATCCGGGGGAAGCGCGAC
AAGGTTCTCATCTCCACCAAGACGGGCCTGCCGATAGGCGATGGCCCGGATGACTGGGGCGTCTCTCGCAGCAGACTGCT
TCGATCGGTAGATGAGGCGCTTTGCCGTCTCGATACGGATTATATCGATATATTACAGCTTCACGCGCTGGACGCGTCCA
CACCGGTTGAGGAATTGCTGTCGACACTTTCCATGCTGGTGCAGGCCGGGAAAGTCCGGCATGTGGGAGTTTCCAATTAT
CCTGGCTGGCAGCTAATGAAAGCCCTCGCCGCAGCTGACCAGCATGGCTGGCCGCGCTTTGTTGCGCATCAGGTGTACTA
CTCCCTGATCGGCCGCGATTATGAGGCTGGCCTCATGCCGCTCGCTGCCGACCAGGGCGTAGGCGCGCTGGTGTGGAGCC
CGCTGGGCTGGGGCCGGCTCACGGGCAAGATCCGCCGCGGAAGCCCGCCGCCCGCCGGAAGCCGGCTGCATGAGACAGAA
CAGTTCGCCCCGCCGGTCGCTGAAGACCACCTTTACCGCGTGGTTGATGCGCTGGATGAGATTGCCGCAGAGACCGGCAA
GGCCGTTCCCCAGATCGCCCTCAACTGGCTGTTGCAGCGCCCAACGGTATCCTCCGTGATCATCGGCGCGCGCAATGAGG
AACAGCTCCTCCAGAATCTGGGGGCTGTGGGCTGGACGTTGACGCCGGATCAGATGGCACGGCTCAACGCCGCAAGCAAA
TTGATGCCCCCTTATCCGTATGCCCCCTATCACTATCAGGAAGGGTTCGCCCGCCTGAACCCGCCACTTCTCTGA

Upstream 100 bases:

>100_bases
GTCTTTGCGTCCATATCAAAGGTCCTTCGCATCCAGAGCACCTAAAATAGTATTTTCCCTCGTCTATCTTTGCGCCCAAC
GCAATTCAAAAGGCATCAAC

Downstream 100 bases:

>100_bases
TCGAAGAGTTATCCATGAAAATCAATCCTCCTCTTCTCGCGCTTGCCGCGGGCGCCTTCGGTATAGGCGTCACCGAGTTT
GCGCCAATGGGCCTGTTGCC

Product: dimethylsulfoxide reductase chain B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MDFRQLGASGLRVPALSFGAGTFGGKGPLFGAWGTNDTDAARRLVDICLDAGVNLFDTADVYSDGASEEVLGAAIRGKRD
KVLISTKTGLPIGDGPDDWGVSRSRLLRSVDEALCRLDTDYIDILQLHALDASTPVEELLSTLSMLVQAGKVRHVGVSNY
PGWQLMKALAAADQHGWPRFVAHQVYYSLIGRDYEAGLMPLAADQGVGALVWSPLGWGRLTGKIRRGSPPPAGSRLHETE
QFAPPVAEDHLYRVVDALDEIAAETGKAVPQIALNWLLQRPTVSSVIIGARNEEQLLQNLGAVGWTLTPDQMARLNAASK
LMPPYPYAPYHYQEGFARLNPPLL

Sequences:

>Translated_344_residues
MDFRQLGASGLRVPALSFGAGTFGGKGPLFGAWGTNDTDAARRLVDICLDAGVNLFDTADVYSDGASEEVLGAAIRGKRD
KVLISTKTGLPIGDGPDDWGVSRSRLLRSVDEALCRLDTDYIDILQLHALDASTPVEELLSTLSMLVQAGKVRHVGVSNY
PGWQLMKALAAADQHGWPRFVAHQVYYSLIGRDYEAGLMPLAADQGVGALVWSPLGWGRLTGKIRRGSPPPAGSRLHETE
QFAPPVAEDHLYRVVDALDEIAAETGKAVPQIALNWLLQRPTVSSVIIGARNEEQLLQNLGAVGWTLTPDQMARLNAASK
LMPPYPYAPYHYQEGFARLNPPLL
>Mature_344_residues
MDFRQLGASGLRVPALSFGAGTFGGKGPLFGAWGTNDTDAARRLVDICLDAGVNLFDTADVYSDGASEEVLGAAIRGKRD
KVLISTKTGLPIGDGPDDWGVSRSRLLRSVDEALCRLDTDYIDILQLHALDASTPVEELLSTLSMLVQAGKVRHVGVSNY
PGWQLMKALAAADQHGWPRFVAHQVYYSLIGRDYEAGLMPLAADQGVGALVWSPLGWGRLTGKIRRGSPPPAGSRLHETE
QFAPPVAEDHLYRVVDALDEIAAETGKAVPQIALNWLLQRPTVSSVIIGARNEEQLLQNLGAVGWTLTPDQMARLNAASK
LMPPYPYAPYHYQEGFARLNPPLL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=342, Percent_Identity=31.8713450292398, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI27436962, Length=342, Percent_Identity=31.5789473684211, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI27436966, Length=342, Percent_Identity=31.5789473684211, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI27436969, Length=311, Percent_Identity=33.1189710610932, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=33.0097087378641, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI27436971, Length=325, Percent_Identity=30.1538461538462, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI223718702, Length=274, Percent_Identity=33.2116788321168, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI41152114, Length=273, Percent_Identity=29.6703296703297, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI41327764, Length=273, Percent_Identity=29.6703296703297, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI223718708, Length=134, Percent_Identity=38.8059701492537, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI87081735, Length=336, Percent_Identity=38.3928571428571, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=34.0425531914894, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789199, Length=356, Percent_Identity=31.1797752808989, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788070, Length=324, Percent_Identity=29.9382716049383, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788081, Length=204, Percent_Identity=30.8823529411765, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994888, Length=315, Percent_Identity=26.984126984127, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787674, Length=316, Percent_Identity=26.5822784810127, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=322, Percent_Identity=26.3975155279503, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325169, Length=349, Percent_Identity=27.5071633237822, Blast_Score=153, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6323998, Length=320, Percent_Identity=31.875, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319958, Length=294, Percent_Identity=30.952380952381, Blast_Score=132, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6322615, Length=252, Percent_Identity=31.3492063492063, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6319951, Length=324, Percent_Identity=28.3950617283951, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=27.9279279279279, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24640980, Length=327, Percent_Identity=25.6880733944954, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45549126, Length=327, Percent_Identity=25.6880733944954, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24646159, Length=167, Percent_Identity=32.9341317365269, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37190; Mature: 37190

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFRQLGASGLRVPALSFGAGTFGGKGPLFGAWGTNDTDAARRLVDICLDAGVNLFDTAD
CCHHHHCCCCCCCCEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEECHH
VYSDGASEEVLGAAIRGKRDKVLISTKTGLPIGDGPDDWGVSRSRLLRSVDEALCRLDTD
HHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCH
YIDILQLHALDASTPVEELLSTLSMLVQAGKVRHVGVSNYPGWQLMKALAAADQHGWPRF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCCHHH
VAHQVYYSLIGRDYEAGLMPLAADQGVGALVWSPLGWGRLTGKIRRGSPPPAGSRLHETE
HHHHHHHHHHCCCCCCCCCEEECCCCCCEEEECCCCCHHHCCEEECCCCCCCCCHHHHHH
QFAPPVAEDHLYRVVDALDEIAAETGKAVPQIALNWLLQRPTVSSVIIGARNEEQLLQNL
HHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHEECCCCHHHHHHHC
GAVGWTLTPDQMARLNAASKLMPPYPYAPYHYQEGFARLNPPLL
CCCCCEECHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHCCCCCC
>Mature Secondary Structure
MDFRQLGASGLRVPALSFGAGTFGGKGPLFGAWGTNDTDAARRLVDICLDAGVNLFDTAD
CCHHHHCCCCCCCCEEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEECHH
VYSDGASEEVLGAAIRGKRDKVLISTKTGLPIGDGPDDWGVSRSRLLRSVDEALCRLDTD
HHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCH
YIDILQLHALDASTPVEELLSTLSMLVQAGKVRHVGVSNYPGWQLMKALAAADQHGWPRF
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCCHHH
VAHQVYYSLIGRDYEAGLMPLAADQGVGALVWSPLGWGRLTGKIRRGSPPPAGSRLHETE
HHHHHHHHHHCCCCCCCCCEEECCCCCCEEEECCCCCHHHCCEEECCCCCCCCCHHHHHH
QFAPPVAEDHLYRVVDALDEIAAETGKAVPQIALNWLLQRPTVSSVIIGARNEEQLLQNL
HHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHEECCCCHHHHHHHC
GAVGWTLTPDQMARLNAASKLMPPYPYAPYHYQEGFARLNPPLL
CCCCCEECHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]