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The map label for this gene is argS

Identifier: 114797992

GI number: 114797992

Start: 2876256

End: 2878025

Strand: Direct

Name: argS

Synonym: HNE_2715

Alternate gene names: 114797992

Gene position: 2876256-2878025 (Clockwise)

Preceding gene: 114800357

Following gene: 114798751

Centisome position: 77.63

GC content: 65.08

Gene sequence:

>1770_bases
ATGACGAGCCTCGCGAAGAACCTGTCCGCGGCCGCTGGCGCCGCCTTTGAGGCAATGGGGCTTGAGGCGCGGTTCGGCGA
GGTGCGCCGGAGCGACAAGCCGGAGCTGGCCGATTTTCAGTGCAATGGCGCGATGGCGGCGGCGAAGGCGGCCGGCAAGA
ACCCGCGCGAGATTGCCGGGGAGATTGCCGCGCGGCTGAAGGAACATGCCTCTGTGCTGTCGGCGGAAGTCGCCGGGCCG
GGCTTTATCAATCTGCGGGTATCGGACGCGGCGCTGTCTGCGCGCGCCGAGCACGTGCGCGGGGACGCGATGGCGGGGGC
GGAGAAAGCCGCAGACGCCGCCGTGACCGTGATCGACTTTGGCGGCGCGAATGTCGCCAAGCCCATGCATGTGGGGCATC
TGCGTTCCGCCGTGATCGGCGATACGCTGCAACGGATCTGCCGGTTTGCGGGTGATGAGGTGACCTCTGACGTGCACCTC
GGCGATTGGGGCCTTCAGATGGGGCACCTGGTTACCGAGCTTTATGACGAACAACCCGGCCTCATCTATTTCGACGCCGC
CTATACTGGCCCCTACCCGGCTGAGCCGCCTGTTACCATTGACGATCTGGGCCGGCTTTATCCACAGGCCAGCAACAAGG
CGAAGGCCGACGCGGCGCGCAATGAGCGCAGCCAGAAGGCTGTCGCCGAAATGCAGGCCGGGCGGCCGGGCTATCGCGCG
CTGCTGCGCCATTTCATCGAGGTGTCGATCGAGGCGCTGAAGCTCGACTATGGCTTCCTCAATGTGTCGTTTGACCTCTG
GAAGGGCGAGAGCGATGTGGACGGGCTGATCCCCGGCCTGGTGGAGCGCTTCAAGCAGGCGGGCCTTGCCGAGGAGAGCG
ACGGCGCGCTGATCGTGCATGTGGCCCGCGAGACCGACAAGAAAGAGATGCCGCCGGTGATGCTGGTCAACAGCCGCGGC
GGCACGGGCTATCACACGACCGACCTTGCGACGATCCTCGACCGGATGGACACGCTGACCACCACGCCCGAGCGGATGCT
CTATGTGGTGGACCAGCGCCAGGCGCTGCATTTCGAGCAGGTGTTCCGCGCCGCCGGGATGCTGGGGCTGATCGCTGAGG
ACAAGCTGGAGCATATCGGCTTTGGCACGGTGAACGGCGCCGATGGCAAGCCCTTCAAGACGCGCGAAGGCGGCGTACTG
CGGCTGGCTGATCTTCAGGCGATGGCGATGGAAGAGGCGGAGAAGAAACTTTCCGCCGCCAACCTGCCCGCAGATATGGG
CGATGCCGAGCGCTTTGATGTGGCGAAAAAAGTGGCCGTCGCGGCGCTGCGTTTCTCGGACCTGATGAACACGCGCACGA
CCAATTATGTGTTCGACCTGGAACGCTTCACCAGCTTTGAGGGCAAGACAGGGCCTTACCTGATGTATGCCGCCGTGCGG
GTGAAATCTGTGCTGCGCAAGGCCGCCGAGAACGGCCATTCTGCGGGCAAGGTGGTGGTTACCGAAGACGCCGAACGCAC
GCTGGTGCTGCAGCTCGACGGCTTTGGCGCGGCGCTTCTGGGCGCGCGCGAAAAGCGGATGCCGCATATCCTGTGCGAAC
ATCTCTACGGCCTCGCCCAGGCGTTCAGCAGCTTCTATGCGGCGTTGCCGATTGCGGCGGAGGCCGATGGCGAGAAGCGC
GCGAGCCGGTTGGCGCTGGCCGATGGCGTGCGGCACCAGTTGGAGACGGGGTTGGAGCTGCTTGGGATTGCTGTGCCGGA
GCGGATGTAG

Upstream 100 bases:

>100_bases
GATTGTGGTGGGCTTCGAGCTGACGACCGAGCAGCTGGAATTCAACCGCGCCGGCAAGCGATTCCGCCTCGATGCGGGCA
CGGGCGTGTCGGAGTAGGAC

Downstream 100 bases:

>100_bases
GGCGGATAGACCCCGGACTTGTTTCAGGCGAAATCTGCCATTGTTGGATATTTGGGTGCGCGTCGGATTCCGGCCTGCGG
TCTCAATCCAACCTATGATG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MTSLAKNLSAAAGAAFEAMGLEARFGEVRRSDKPELADFQCNGAMAAAKAAGKNPREIAGEIAARLKEHASVLSAEVAGP
GFINLRVSDAALSARAEHVRGDAMAGAEKAADAAVTVIDFGGANVAKPMHVGHLRSAVIGDTLQRICRFAGDEVTSDVHL
GDWGLQMGHLVTELYDEQPGLIYFDAAYTGPYPAEPPVTIDDLGRLYPQASNKAKADAARNERSQKAVAEMQAGRPGYRA
LLRHFIEVSIEALKLDYGFLNVSFDLWKGESDVDGLIPGLVERFKQAGLAEESDGALIVHVARETDKKEMPPVMLVNSRG
GTGYHTTDLATILDRMDTLTTTPERMLYVVDQRQALHFEQVFRAAGMLGLIAEDKLEHIGFGTVNGADGKPFKTREGGVL
RLADLQAMAMEEAEKKLSAANLPADMGDAERFDVAKKVAVAALRFSDLMNTRTTNYVFDLERFTSFEGKTGPYLMYAAVR
VKSVLRKAAENGHSAGKVVVTEDAERTLVLQLDGFGAALLGAREKRMPHILCEHLYGLAQAFSSFYAALPIAAEADGEKR
ASRLALADGVRHQLETGLELLGIAVPERM

Sequences:

>Translated_589_residues
MTSLAKNLSAAAGAAFEAMGLEARFGEVRRSDKPELADFQCNGAMAAAKAAGKNPREIAGEIAARLKEHASVLSAEVAGP
GFINLRVSDAALSARAEHVRGDAMAGAEKAADAAVTVIDFGGANVAKPMHVGHLRSAVIGDTLQRICRFAGDEVTSDVHL
GDWGLQMGHLVTELYDEQPGLIYFDAAYTGPYPAEPPVTIDDLGRLYPQASNKAKADAARNERSQKAVAEMQAGRPGYRA
LLRHFIEVSIEALKLDYGFLNVSFDLWKGESDVDGLIPGLVERFKQAGLAEESDGALIVHVARETDKKEMPPVMLVNSRG
GTGYHTTDLATILDRMDTLTTTPERMLYVVDQRQALHFEQVFRAAGMLGLIAEDKLEHIGFGTVNGADGKPFKTREGGVL
RLADLQAMAMEEAEKKLSAANLPADMGDAERFDVAKKVAVAALRFSDLMNTRTTNYVFDLERFTSFEGKTGPYLMYAAVR
VKSVLRKAAENGHSAGKVVVTEDAERTLVLQLDGFGAALLGAREKRMPHILCEHLYGLAQAFSSFYAALPIAAEADGEKR
ASRLALADGVRHQLETGLELLGIAVPERM
>Mature_588_residues
TSLAKNLSAAAGAAFEAMGLEARFGEVRRSDKPELADFQCNGAMAAAKAAGKNPREIAGEIAARLKEHASVLSAEVAGPG
FINLRVSDAALSARAEHVRGDAMAGAEKAADAAVTVIDFGGANVAKPMHVGHLRSAVIGDTLQRICRFAGDEVTSDVHLG
DWGLQMGHLVTELYDEQPGLIYFDAAYTGPYPAEPPVTIDDLGRLYPQASNKAKADAARNERSQKAVAEMQAGRPGYRAL
LRHFIEVSIEALKLDYGFLNVSFDLWKGESDVDGLIPGLVERFKQAGLAEESDGALIVHVARETDKKEMPPVMLVNSRGG
TGYHTTDLATILDRMDTLTTTPERMLYVVDQRQALHFEQVFRAAGMLGLIAEDKLEHIGFGTVNGADGKPFKTREGGVLR
LADLQAMAMEEAEKKLSAANLPADMGDAERFDVAKKVAVAALRFSDLMNTRTTNYVFDLERFTSFEGKTGPYLMYAAVRV
KSVLRKAAENGHSAGKVVVTEDAERTLVLQLDGFGAALLGAREKRMPHILCEHLYGLAQAFSSFYAALPIAAEADGEKRA
SRLALADGVRHQLETGLELLGIAVPERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=587, Percent_Identity=30.4940374787053, Blast_Score=257, Evalue=3e-68,
Organism=Homo sapiens, GI197100773, Length=570, Percent_Identity=26.6666666666667, Blast_Score=155, Evalue=1e-37,
Organism=Escherichia coli, GI1788184, Length=575, Percent_Identity=36.695652173913, Blast_Score=329, Evalue=4e-91,
Organism=Caenorhabditis elegans, GI71985061, Length=586, Percent_Identity=29.8634812286689, Blast_Score=232, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI71985068, Length=551, Percent_Identity=29.5825771324864, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17532153, Length=494, Percent_Identity=26.9230769230769, Blast_Score=115, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320548, Length=559, Percent_Identity=29.1592128801431, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6321883, Length=559, Percent_Identity=26.654740608229, Blast_Score=167, Evalue=3e-42,
Organism=Drosophila melanogaster, GI18859963, Length=576, Percent_Identity=27.9513888888889, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI28571570, Length=481, Percent_Identity=28.2744282744283, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_HYPNA (Q0BYP8)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_761395.1
- ProteinModelPortal:   Q0BYP8
- SMR:   Q0BYP8
- STRING:   Q0BYP8
- GeneID:   4289313
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_2715
- NMPDR:   fig|228405.5.peg.2602
- TIGR:   HNE_2715
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- PhylomeDB:   Q0BYP8
- ProtClustDB:   PRK01611
- BioCyc:   HNEP81032:HNE_2715-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63442; Mature: 63311

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLAKNLSAAAGAAFEAMGLEARFGEVRRSDKPELADFQCNGAMAAAKAAGKNPREIAG
CCCHHHHHHHHHCCHHHHHCCHHHHHHHHCCCCCCCCCEECCCCHHHHHHCCCCHHHHHH
EIAARLKEHASVLSAEVAGPGFINLRVSDAALSARAEHVRGDAMAGAEKAADAAVTVIDF
HHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCHHHCCHHHHCCCEEEEEEC
GGANVAKPMHVGHLRSAVIGDTLQRICRFAGDEVTSDVHLGDWGLQMGHLVTELYDEQPG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
LIYFDAAYTGPYPAEPPVTIDDLGRLYPQASNKAKADAARNERSQKAVAEMQAGRPGYRA
EEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
LLRHFIEVSIEALKLDYGFLNVSFDLWKGESDVDGLIPGLVERFKQAGLAEESDGALIVH
HHHHHHHHHHHHEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
VARETDKKEMPPVMLVNSRGGTGYHTTDLATILDRMDTLTTTPERMLYVVDQRQALHFEQ
EECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEECCHHHHHHHH
VFRAAGMLGLIAEDKLEHIGFGTVNGADGKPFKTREGGVLRLADLQAMAMEEAEKKLSAA
HHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHC
NLPADMGDAERFDVAKKVAVAALRFSDLMNTRTTNYVFDLERFTSFEGKTGPYLMYAAVR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCCCCHHHHHHH
VKSVLRKAAENGHSAGKVVVTEDAERTLVLQLDGFGAALLGAREKRMPHILCEHLYGLAQ
HHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCHHHHCCHHHCCHHHHHHHHHHHHH
AFSSFYAALPIAAEADGEKRASRLALADGVRHQLETGLELLGIAVPERM
HHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC
>Mature Secondary Structure 
TSLAKNLSAAAGAAFEAMGLEARFGEVRRSDKPELADFQCNGAMAAAKAAGKNPREIAG
CCHHHHHHHHHCCHHHHHCCHHHHHHHHCCCCCCCCCEECCCCHHHHHHCCCCHHHHHH
EIAARLKEHASVLSAEVAGPGFINLRVSDAALSARAEHVRGDAMAGAEKAADAAVTVIDF
HHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCHHHCCHHHHCCCEEEEEEC
GGANVAKPMHVGHLRSAVIGDTLQRICRFAGDEVTSDVHLGDWGLQMGHLVTELYDEQPG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
LIYFDAAYTGPYPAEPPVTIDDLGRLYPQASNKAKADAARNERSQKAVAEMQAGRPGYRA
EEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
LLRHFIEVSIEALKLDYGFLNVSFDLWKGESDVDGLIPGLVERFKQAGLAEESDGALIVH
HHHHHHHHHHHHEEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
VARETDKKEMPPVMLVNSRGGTGYHTTDLATILDRMDTLTTTPERMLYVVDQRQALHFEQ
EECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHEEEEECCHHHHHHHH
VFRAAGMLGLIAEDKLEHIGFGTVNGADGKPFKTREGGVLRLADLQAMAMEEAEKKLSAA
HHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHC
NLPADMGDAERFDVAKKVAVAALRFSDLMNTRTTNYVFDLERFTSFEGKTGPYLMYAAVR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCCCCHHHHHHH
VKSVLRKAAENGHSAGKVVVTEDAERTLVLQLDGFGAALLGAREKRMPHILCEHLYGLAQ
HHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCHHHHCCHHHCCHHHHHHHHHHHHH
AFSSFYAALPIAAEADGEKRASRLALADGVRHQLETGLELLGIAVPERM
HHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA