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The map label for this gene is xylB [H]

Identifier: 114797944

GI number: 114797944

Start: 1524067

End: 1525185

Strand: Reverse

Name: xylB [H]

Synonym: HNE_1493

Alternate gene names: 114797944

Gene position: 1525185-1524067 (Counterclockwise)

Preceding gene: 114798032

Following gene: 114799249

Centisome position: 41.17

GC content: 61.39

Gene sequence:

>1119_bases
ATGACAAAAAAAGCGCAGGCTGCCGTAATCGAACGGACCGATGATCCCTTCGTTATACAAGATATCACCCTTGATGCGCC
CCGGCCGGATGAAGTGATCGTCCGTATGGTGGCAACAGGTATCTGCGCAACCGACGCGCATGTGCGCCAACAATCAATTC
CGGCACCGTTACCGGCAATCCTCGGTCATGAGGGTGCAGGCGTGGTGGAACGGGTCGGATCGGCTGTCACCCACGTGAAA
GCCGGAGATCACGTCGTCCTGTCCTTTCACGCCTGCGGACAGTGCAAGCCATGCCTGTCCTCTCATGCGGCCTATTGTGA
CAAAGTCTGGGAGGCCAACTTCGCAGGCGCGAGACTGGATGGCTCCACAGGGATCCGGCGCGAGGGTCCGGACAGGCTCC
ATGCTCACTTCTTCGGTCAGTCCTCGTTTGCCACCTATGCGCTCGCCCACCAGCGCAACACCATCAAGGTTCCCTCCGAC
ATTCCCCTGGAGATCCTCGGACCTCTTGGTTGCGGCATGCAGACCGGCGCGGGGGCGATCCTCAAGGCGTTGAAAGTCCC
GGTCGGCGCCACGGTTGCGATCTTCGGCGTCGGCGCGGTCGGCCTTGCCGCGATCATGGCCGCCAGGATTGCAGACGCGA
TGACCGTCATCGCCATCGACGTGAACGCCGGGAGGCTGGAGCTGGCGGGGGAACTGGGCGCGACGCATGTCATCAATGCA
GCCAGCAATAAAAACATCGCCGCTGCGATCCGGCAGATCGAGCCGCGCGGCATCGAGTTTGTGCTCGACACCAGCGGGCG
GGCATCAAACCTTGATGCCGGAATTGCGGCGCTCGCGCCAATGGGCCATTTCGGGTTCGTCGCCTTCAACGACCATTCTG
GGGCCGTTGTGGACGCCTCCCGCCTGACCCTCGGGCAGACACTCCAGGGCATCATCCAGGGTGACGCTGTACCGGCACTG
ATGATTCCCGAGCTGATTGGCCTCTATCGCAGCGGCCGTTTCCCCTTCGACCGGCTCATCACTTTTTACGATTTCGCCGA
CATCAACCAGGCATTCGAAGATGTCGCTGCCGGCCGCGTCATCAAGGCAGTCCTCCGCTTCAAACCTTCGGCTGAGTAA

Upstream 100 bases:

>100_bases
TGCAGAAACATCCGCTGCACGCTCGCGTCAAAACTCGACGGAGACCGCCGATGAAAAAATCAAAAGTCCCTGATTATAAG
CGCTTTTGTGAGAAGCCTGC

Downstream 100 bases:

>100_bases
GCGGCTGAACTCCATGACCAGAACCAAGAAGGACGCAAACAATGTGTGACAAGCATCAGAAGCCTATCACAGCTTCAGAT
ACACCCGGTTTCTATGGCAT

Product: aryl-alcohol dehydrogenase

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTKKAQAAVIERTDDPFVIQDITLDAPRPDEVIVRMVATGICATDAHVRQQSIPAPLPAILGHEGAGVVERVGSAVTHVK
AGDHVVLSFHACGQCKPCLSSHAAYCDKVWEANFAGARLDGSTGIRREGPDRLHAHFFGQSSFATYALAHQRNTIKVPSD
IPLEILGPLGCGMQTGAGAILKALKVPVGATVAIFGVGAVGLAAIMAARIADAMTVIAIDVNAGRLELAGELGATHVINA
ASNKNIAAAIRQIEPRGIEFVLDTSGRASNLDAGIAALAPMGHFGFVAFNDHSGAVVDASRLTLGQTLQGIIQGDAVPAL
MIPELIGLYRSGRFPFDRLITFYDFADINQAFEDVAAGRVIKAVLRFKPSAE

Sequences:

>Translated_372_residues
MTKKAQAAVIERTDDPFVIQDITLDAPRPDEVIVRMVATGICATDAHVRQQSIPAPLPAILGHEGAGVVERVGSAVTHVK
AGDHVVLSFHACGQCKPCLSSHAAYCDKVWEANFAGARLDGSTGIRREGPDRLHAHFFGQSSFATYALAHQRNTIKVPSD
IPLEILGPLGCGMQTGAGAILKALKVPVGATVAIFGVGAVGLAAIMAARIADAMTVIAIDVNAGRLELAGELGATHVINA
ASNKNIAAAIRQIEPRGIEFVLDTSGRASNLDAGIAALAPMGHFGFVAFNDHSGAVVDASRLTLGQTLQGIIQGDAVPAL
MIPELIGLYRSGRFPFDRLITFYDFADINQAFEDVAAGRVIKAVLRFKPSAE
>Mature_371_residues
TKKAQAAVIERTDDPFVIQDITLDAPRPDEVIVRMVATGICATDAHVRQQSIPAPLPAILGHEGAGVVERVGSAVTHVKA
GDHVVLSFHACGQCKPCLSSHAAYCDKVWEANFAGARLDGSTGIRREGPDRLHAHFFGQSSFATYALAHQRNTIKVPSDI
PLEILGPLGCGMQTGAGAILKALKVPVGATVAIFGVGAVGLAAIMAARIADAMTVIAIDVNAGRLELAGELGATHVINAA
SNKNIAAAIRQIEPRGIEFVLDTSGRASNLDAGIAALAPMGHFGFVAFNDHSGAVVDASRLTLGQTLQGIIQGDAVPALM
IPELIGLYRSGRFPFDRLITFYDFADINQAFEDVAAGRVIKAVLRFKPSAE

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501929, Length=373, Percent_Identity=35.9249329758713, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI34577061, Length=372, Percent_Identity=36.0215053763441, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI4501933, Length=372, Percent_Identity=35.4838709677419, Blast_Score=212, Evalue=5e-55,
Organism=Homo sapiens, GI71565154, Length=373, Percent_Identity=32.171581769437, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI71565152, Length=372, Percent_Identity=32.7956989247312, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI71743840, Length=372, Percent_Identity=32.5268817204301, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI262073058, Length=372, Percent_Identity=32.5268817204301, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI156523966, Length=374, Percent_Identity=31.8181818181818, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI4501939, Length=373, Percent_Identity=31.3672922252011, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI1786552, Length=377, Percent_Identity=32.0954907161804, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1788073, Length=354, Percent_Identity=27.9661016949153, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1788407, Length=279, Percent_Identity=26.1648745519713, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87082125, Length=361, Percent_Identity=24.9307479224377, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1790045, Length=366, Percent_Identity=26.2295081967213, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081918, Length=254, Percent_Identity=32.6771653543307, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788075, Length=281, Percent_Identity=27.4021352313167, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786825, Length=270, Percent_Identity=28.5185185185185, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787863, Length=363, Percent_Identity=23.9669421487603, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786518, Length=264, Percent_Identity=25, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25146526, Length=377, Percent_Identity=32.8912466843501, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71997431, Length=379, Percent_Identity=32.7176781002639, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17565904, Length=344, Percent_Identity=32.2674418604651, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71988145, Length=261, Percent_Identity=30.6513409961686, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562584, Length=366, Percent_Identity=24.8633879781421, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562582, Length=314, Percent_Identity=23.8853503184713, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320033, Length=372, Percent_Identity=32.7956989247312, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6319621, Length=296, Percent_Identity=28.7162162162162, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323729, Length=289, Percent_Identity=26.9896193771626, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=263, Percent_Identity=28.5171102661597, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319258, Length=288, Percent_Identity=26.7361111111111, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=257, Percent_Identity=29.5719844357977, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319949, Length=225, Percent_Identity=31.1111111111111, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737895, Length=379, Percent_Identity=32.4538258575198, Blast_Score=186, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 39008; Mature: 38877

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKAQAAVIERTDDPFVIQDITLDAPRPDEVIVRMVATGICATDAHVRQQSIPAPLPAI
CCCCCCCCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHH
LGHEGAGVVERVGSAVTHVKAGDHVVLSFHACGQCKPCLSSHAAYCDKVWEANFAGARLD
HCCCCCHHHHHHHHHHHEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEC
GSTGIRREGPDRLHAHFFGQSSFATYALAHQRNTIKVPSDIPLEILGPLGCGMQTGAGAI
CCCCCCCCCCCHHHHEECCCCCHHHEEEECCCCEEECCCCCCHHHHCCCCCCCCCCHHHH
LKALKVPVGATVAIFGVGAVGLAAIMAARIADAMTVIAIDVNAGRLELAGELGATHVINA
HHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEECCCCCCCEEEEC
ASNKNIAAAIRQIEPRGIEFVLDTSGRASNLDAGIAALAPMGHFGFVAFNDHSGAVVDAS
CCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCEEEHH
RLTLGQTLQGIIQGDAVPALMIPELIGLYRSGRFPFDRLITFYDFADINQAFEDVAAGRV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IKAVLRFKPSAE
HHHHHHCCCCCC
>Mature Secondary Structure 
TKKAQAAVIERTDDPFVIQDITLDAPRPDEVIVRMVATGICATDAHVRQQSIPAPLPAI
CCCCCCCEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHH
LGHEGAGVVERVGSAVTHVKAGDHVVLSFHACGQCKPCLSSHAAYCDKVWEANFAGARLD
HCCCCCHHHHHHHHHHHEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEC
GSTGIRREGPDRLHAHFFGQSSFATYALAHQRNTIKVPSDIPLEILGPLGCGMQTGAGAI
CCCCCCCCCCCHHHHEECCCCCHHHEEEECCCCEEECCCCCCHHHHCCCCCCCCCCHHHH
LKALKVPVGATVAIFGVGAVGLAAIMAARIADAMTVIAIDVNAGRLELAGELGATHVINA
HHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEECCCCCCCEEEEC
ASNKNIAAAIRQIEPRGIEFVLDTSGRASNLDAGIAALAPMGHFGFVAFNDHSGAVVDAS
CCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCEEEHH
RLTLGQTLQGIIQGDAVPALMIPELIGLYRSGRFPFDRLITFYDFADINQAFEDVAAGRV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IKAVLRFKPSAE
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]