Click here to switch to the map view.

The map label for this gene is aatA [H]

Identifier: 114797936

GI number: 114797936

Start: 3124579

End: 3125790

Strand: Direct

Name: aatA [H]

Synonym: HNE_2968

Alternate gene names: 114797936

Gene position: 3124579-3125790 (Clockwise)

Preceding gene: 114797624

Following gene: 114797861

Centisome position: 84.33

GC content: 63.78

Gene sequence:

>1212_bases
ATGGCCGCCGACATCCGCCTGTCAGACGCAATCGCCCGCGTGAAACCTTCCGCCACGATTGCCGTGACGACCAAGGCCAA
CGAGATGAAGCGCCAGGGGCTGGATGTGATCGGCCTCGGCGCTGGCGAGCCTGACTTCGACACCCCGGAAAACATCAAGG
AAGCCGCCATCCGGGCCATGCGCGAAGGCAAGACGAAATACACGCCTTCCGACGGTATCCCGGAGCTCAAGGAAGCCATC
GTGGCCAAGTTCGCCCGCGAGAATGGCCTCACCTACAAGCCCTCGCAGGTGAACGTGTCGCCCGGCGGCAAGGCCGTGCT
GTTCAATGCTTTCATGGCGACGCTGAACGCAGGCGACGAGGTGGTGATCCCGGCGCCCTACTGGGTGAGCTATCCGGAGA
TGGTGCTGCTCTGTGGCGCCACGCCGGTTGCCGTGCCCTGCGGCGCCGACACCGCCTACAAGCTGAGCCCGGAGAAACTC
GAAGCGGCGATCACGCCCAAGACCAAATGGCTGATCCTGAACTCTCCGTCCAACCCCACCGGCGCGGCCTATACCGGCGC
TGAGCTGAAAGCCCTTGCGGACGTGCTGCTGCGCCATCCCCAAGTCTGGATACTGACGGACGACATGTATGAGCACCTTG
TCTATGACGGGTTCGAGTACAAGACGATCGCGCAAGTCGAGCCGGCCCTCTATGACCGCACGCTGACGATGAACGGCGTG
TCGAAAGCCTATGCCATGACCGGGTGGCGCATCGGCTATGCCGCGGGGCCGGAGAAACTGATCGGCGCGATGCGCAAGGT
GATGGACCAGTCCACCTCCAACCCCTGCTCCATCAGCCAGTGGGCGAGCGTCGAGGCGCTGAACGGCCCGCAGGACTTCC
TGCCTGTCTTCCGCGCCGCCTATGCCAAGCGCCGCAACCTGATGGTTGATGGCCTCAACCAGGCTGCCGGCATCGTCTGC
CCGAAGCCCGAAGGTGCCTTCTATGTGTACCCATCCTGCGCGGGCCTGATCGGCAAGAAGACCGCCGGCGGCGCGGTGAT
CGACAGCGACAAGACATTCGCGGCCGAACTGCTGGAACAGGAAAAAGTCGCGATTGTGTTCGGCGAAGCCTTCGGCCTGC
CCGAGACCTTCCGCATTTCCTATGCGACCTCTGACGCCGCACTGACCGAGGCGCTCGTCCGCATCCAGCGTTTCTGCGCC
AGCCTCTCCTAG

Upstream 100 bases:

>100_bases
CAAGAGCAAGCGCCAAAACAGCGCCTTGATGACCCGCAGGGCCTCCAGTAAGCGTGCGCCAAACACCCCCCTTGACCACC
CCTTCGAAGAGGACCGCCCC

Downstream 100 bases:

>100_bases
AGGCATAGGCAGAACCTATAGTCGCAGCCATCGTTTCGGATTTGAAACCTGGCCTCTTCGTGCCCATCTTGAGGGCATGT
TGGGGCTTGACCCCTTATGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MAADIRLSDAIARVKPSATIAVTTKANEMKRQGLDVIGLGAGEPDFDTPENIKEAAIRAMREGKTKYTPSDGIPELKEAI
VAKFARENGLTYKPSQVNVSPGGKAVLFNAFMATLNAGDEVVIPAPYWVSYPEMVLLCGATPVAVPCGADTAYKLSPEKL
EAAITPKTKWLILNSPSNPTGAAYTGAELKALADVLLRHPQVWILTDDMYEHLVYDGFEYKTIAQVEPALYDRTLTMNGV
SKAYAMTGWRIGYAAGPEKLIGAMRKVMDQSTSNPCSISQWASVEALNGPQDFLPVFRAAYAKRRNLMVDGLNQAAGIVC
PKPEGAFYVYPSCAGLIGKKTAGGAVIDSDKTFAAELLEQEKVAIVFGEAFGLPETFRISYATSDAALTEALVRIQRFCA
SLS

Sequences:

>Translated_403_residues
MAADIRLSDAIARVKPSATIAVTTKANEMKRQGLDVIGLGAGEPDFDTPENIKEAAIRAMREGKTKYTPSDGIPELKEAI
VAKFARENGLTYKPSQVNVSPGGKAVLFNAFMATLNAGDEVVIPAPYWVSYPEMVLLCGATPVAVPCGADTAYKLSPEKL
EAAITPKTKWLILNSPSNPTGAAYTGAELKALADVLLRHPQVWILTDDMYEHLVYDGFEYKTIAQVEPALYDRTLTMNGV
SKAYAMTGWRIGYAAGPEKLIGAMRKVMDQSTSNPCSISQWASVEALNGPQDFLPVFRAAYAKRRNLMVDGLNQAAGIVC
PKPEGAFYVYPSCAGLIGKKTAGGAVIDSDKTFAAELLEQEKVAIVFGEAFGLPETFRISYATSDAALTEALVRIQRFCA
SLS
>Mature_402_residues
AADIRLSDAIARVKPSATIAVTTKANEMKRQGLDVIGLGAGEPDFDTPENIKEAAIRAMREGKTKYTPSDGIPELKEAIV
AKFARENGLTYKPSQVNVSPGGKAVLFNAFMATLNAGDEVVIPAPYWVSYPEMVLLCGATPVAVPCGADTAYKLSPEKLE
AAITPKTKWLILNSPSNPTGAAYTGAELKALADVLLRHPQVWILTDDMYEHLVYDGFEYKTIAQVEPALYDRTLTMNGVS
KAYAMTGWRIGYAAGPEKLIGAMRKVMDQSTSNPCSISQWASVEALNGPQDFLPVFRAAYAKRRNLMVDGLNQAAGIVCP
KPEGAFYVYPSCAGLIGKKTAGGAVIDSDKTFAAELLEQEKVAIVFGEAFGLPETFRISYATSDAALTEALVRIQRFCAS
LS

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=397, Percent_Identity=27.9596977329975, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI169881279, Length=397, Percent_Identity=27.9596977329975, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI56713254, Length=313, Percent_Identity=29.7124600638978, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI56713256, Length=382, Percent_Identity=27.4869109947644, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI169881281, Length=394, Percent_Identity=23.8578680203046, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=23.8219895287958, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1788627, Length=392, Percent_Identity=28.3163265306122, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1788722, Length=350, Percent_Identity=31.4285714285714, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1786816, Length=320, Percent_Identity=27.5, Blast_Score=136, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=26.9633507853403, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=291, Percent_Identity=28.1786941580756, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=291, Percent_Identity=28.1786941580756, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=386, Percent_Identity=24.0932642487047, Blast_Score=111, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=313, Percent_Identity=28.7539936102236, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28573069, Length=323, Percent_Identity=28.4829721362229, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24646114, Length=323, Percent_Identity=28.4829721362229, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28573067, Length=323, Percent_Identity=28.4829721362229, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28573065, Length=323, Percent_Identity=28.4829721362229, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI18859735, Length=379, Percent_Identity=23.2189973614776, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43336; Mature: 43205

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADIRLSDAIARVKPSATIAVTTKANEMKRQGLDVIGLGAGEPDFDTPENIKEAAIRAM
CCCCCCHHHHHHHCCCCEEEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHH
REGKTKYTPSDGIPELKEAIVAKFARENGLTYKPSQVNVSPGGKAVLFNAFMATLNAGDE
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCEEEECCCCCCHHHHHHHHHHCCCCC
VVIPAPYWVSYPEMVLLCGATPVAVPCGADTAYKLSPEKLEAAITPKTKWLILNSPSNPT
EEECCCCCCCCCCEEEEECCCCEEEECCCCCCEEECHHHHHEEECCCEEEEEEECCCCCC
GAAYTGAELKALADVLLRHPQVWILTDDMYEHLVYDGFEYKTIAQVEPALYDRTLTMNGV
CCEECCHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCCEEHHHCCHHHHCCEEEECCC
SKAYAMTGWRIGYAAGPEKLIGAMRKVMDQSTSNPCSISQWASVEALNGPQDFLPVFRAA
HHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHCCCEEECCCCHHHHHHHHHH
YAKRRNLMVDGLNQAAGIVCPKPEGAFYVYPSCAGLIGKKTAGGAVIDSDKTFAAELLEQ
HHHHCCCEEECCCCCCCEEECCCCCCEEECCCHHCHHCCCCCCCEEEECCCHHHHHHHCC
EKVAIVFGEAFGLPETFRISYATSDAALTEALVRIQRFCASLS
CCEEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AADIRLSDAIARVKPSATIAVTTKANEMKRQGLDVIGLGAGEPDFDTPENIKEAAIRAM
CCCCCHHHHHHHCCCCEEEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHH
REGKTKYTPSDGIPELKEAIVAKFARENGLTYKPSQVNVSPGGKAVLFNAFMATLNAGDE
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCEEEECCCCCCHHHHHHHHHHCCCCC
VVIPAPYWVSYPEMVLLCGATPVAVPCGADTAYKLSPEKLEAAITPKTKWLILNSPSNPT
EEECCCCCCCCCCEEEEECCCCEEEECCCCCCEEECHHHHHEEECCCEEEEEEECCCCCC
GAAYTGAELKALADVLLRHPQVWILTDDMYEHLVYDGFEYKTIAQVEPALYDRTLTMNGV
CCEECCHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCCEEHHHCCHHHHCCEEEECCC
SKAYAMTGWRIGYAAGPEKLIGAMRKVMDQSTSNPCSISQWASVEALNGPQDFLPVFRAA
HHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHCCCEEECCCCHHHHHHHHHH
YAKRRNLMVDGLNQAAGIVCPKPEGAFYVYPSCAGLIGKKTAGGAVIDSDKTFAAELLEQ
HHHHCCCEEECCCCCCCEEECCCCCCEEECCCHHCHHCCCCCCCEEEECCCHHHHHHHCC
EKVAIVFGEAFGLPETFRISYATSDAALTEALVRIQRFCASLS
CCEEEEEECCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]