Click here to switch to the map view.

The map label for this gene is citZ [H]

Identifier: 114797889

GI number: 114797889

Start: 3590675

End: 3591805

Strand: Direct

Name: citZ [H]

Synonym: HNE_3454

Alternate gene names: 114797889

Gene position: 3590675-3591805 (Clockwise)

Preceding gene: 114799752

Following gene: 114799291

Centisome position: 96.91

GC content: 66.22

Gene sequence:

>1131_bases
ATGTTGTGGATCGGACGCGAAGAGGCCCTCGGCGCGCTGGGCGTAAAACCCCAGACCCTCTACGCCTATGTCAGCCGCGG
ACTGATCGCGGCCCGGCCGGACACCGATGATCCCCGGTCGAGTCTCTATTCCTCCTCCGATATTGCCACTCTGGTGAAAC
GGCGGCGCAGCGGCCGGGGCCGCGAAGCCATTGCGCAGGGCGCCATTTCCTGGGGCGAACCGGTCATGGAAACGGCGATC
ACTACGGTGCGCAACGGCCGTCTGATCTATCGCGGCAAGGACGCTGTGCGCCTCTCGGCAGACGCAACTCTGGAGGAGGC
AGCTGCCCTCCTCTGGAATGCCGGGGCATTGCCCCCAGCCCGCGCCGCTGAATTGCCCTCCGGCGGACCGACCGGCAAGG
CGCGCGCGCTCGCATTTCTCGCGGCCCGCGCGGCTCAAGACACACCGAGCTTCGCCAGACACCCCACCTCTCTGGCCAGA
GAGGGCAGCGAACTGCTCGCCGGCTTCTGCACGGCCGTTACCGGTACGACCGGACGCGGCTTCTTCCATCAGCGCCTTGC
CCGTCATTGGGGCCTTTCTCCGGGCGGGACCGATCTCGTCCGGCGCGCACTGGTGCTGGTGGCAGACCATGAGCTGAACC
CGTCCACTTTTGCCGCGCGGGTGGCCGCGTCGACTGGCGCCCCATTAGCGGCTTGCGCCCTGGCAGGATGCGCGACATTG
ACCGGCCCGCTGCATGGTGAAGCGTCGCAACGCGCTCTGATCTATCTCAAGCGCGCGCTTGAGGACGGCCCGGAAACGGC
GCTTGCCGGCCTGGCAGACAGCGGTGAACCAATTCCTGCGACAGGACATACCCTTTACCCCGAAGGCGACCCCCGTGCGG
GCGCCCTGCTTCGCTGGATGAAACCGGGCGGGGATTTGAAGCGCGCCATTCGCGCCGCAGAGAACCATACCGGCGCCCGC
GCCAATATCGACATGGCGCTGGCCGCGCTTAGCGTTCAGCTTGAGCTACCGGAGGACGCGCCGTTCCTTATCTTTGCGAG
CGGGCGTATGGCAGGCTGGATCGCCCACGCCATAGAACAAGTCTCCAGCGGCAAGACCATCCGCCCACGGGCAAATTATA
TGGAGGACTAA

Upstream 100 bases:

>100_bases
ATATTCTCAAGTCCGGAATCCATAAGTGTCTCCCTGATTTCCTGAGATCAAATTCGCCCTGGCCCTGTTCAGCGTCAATC
TTGATCAATATAATCAACAT

Downstream 100 bases:

>100_bases
ATCAGACCCGCTCTTTGATCGCGGCAACGGCGGCTTCCGCCGTGATGCCGAAATGCTGGTAGAGTTTCTGATAGGGCGCG
CTGGCGCCGAAGCTGTCCAT

Product: citrate synthase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MLWIGREEALGALGVKPQTLYAYVSRGLIAARPDTDDPRSSLYSSSDIATLVKRRRSGRGREAIAQGAISWGEPVMETAI
TTVRNGRLIYRGKDAVRLSADATLEEAAALLWNAGALPPARAAELPSGGPTGKARALAFLAARAAQDTPSFARHPTSLAR
EGSELLAGFCTAVTGTTGRGFFHQRLARHWGLSPGGTDLVRRALVLVADHELNPSTFAARVAASTGAPLAACALAGCATL
TGPLHGEASQRALIYLKRALEDGPETALAGLADSGEPIPATGHTLYPEGDPRAGALLRWMKPGGDLKRAIRAAENHTGAR
ANIDMALAALSVQLELPEDAPFLIFASGRMAGWIAHAIEQVSSGKTIRPRANYMED

Sequences:

>Translated_376_residues
MLWIGREEALGALGVKPQTLYAYVSRGLIAARPDTDDPRSSLYSSSDIATLVKRRRSGRGREAIAQGAISWGEPVMETAI
TTVRNGRLIYRGKDAVRLSADATLEEAAALLWNAGALPPARAAELPSGGPTGKARALAFLAARAAQDTPSFARHPTSLAR
EGSELLAGFCTAVTGTTGRGFFHQRLARHWGLSPGGTDLVRRALVLVADHELNPSTFAARVAASTGAPLAACALAGCATL
TGPLHGEASQRALIYLKRALEDGPETALAGLADSGEPIPATGHTLYPEGDPRAGALLRWMKPGGDLKRAIRAAENHTGAR
ANIDMALAALSVQLELPEDAPFLIFASGRMAGWIAHAIEQVSSGKTIRPRANYMED
>Mature_376_residues
MLWIGREEALGALGVKPQTLYAYVSRGLIAARPDTDDPRSSLYSSSDIATLVKRRRSGRGREAIAQGAISWGEPVMETAI
TTVRNGRLIYRGKDAVRLSADATLEEAAALLWNAGALPPARAAELPSGGPTGKARALAFLAARAAQDTPSFARHPTSLAR
EGSELLAGFCTAVTGTTGRGFFHQRLARHWGLSPGGTDLVRRALVLVADHELNPSTFAARVAASTGAPLAACALAGCATL
TGPLHGEASQRALIYLKRALEDGPETALAGLADSGEPIPATGHTLYPEGDPRAGALLRWMKPGGDLKRAIRAAENHTGAR
ANIDMALAALSVQLELPEDAPFLIFASGRMAGWIAHAIEQVSSGKTIRPRANYMED

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786527, Length=357, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786939, Length=192, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 39548; Mature: 39548

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWIGREEALGALGVKPQTLYAYVSRGLIAARPDTDDPRSSLYSSSDIATLVKRRRSGRG
CCCCCCHHHHHHCCCCHHHHHHHHHCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHCCCC
REAIAQGAISWGEPVMETAITTVRNGRLIYRGKDAVRLSADATLEEAAALLWNAGALPPA
HHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCCCCH
RAAELPSGGPTGKARALAFLAARAAQDTPSFARHPTSLAREGSELLAGFCTAVTGTTGRG
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCH
FFHQRLARHWGLSPGGTDLVRRALVLVADHELNPSTFAARVAASTGAPLAACALAGCATL
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
TGPLHGEASQRALIYLKRALEDGPETALAGLADSGEPIPATGHTLYPEGDPRAGALLRWM
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHEEC
KPGGDLKRAIRAAENHTGARANIDMALAALSVQLELPEDAPFLIFASGRMAGWIAHAIEQ
CCCHHHHHHHHHHHCCCCCCCCHHHEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHH
VSSGKTIRPRANYMED
HHCCCEECCCCCCCCC
>Mature Secondary Structure
MLWIGREEALGALGVKPQTLYAYVSRGLIAARPDTDDPRSSLYSSSDIATLVKRRRSGRG
CCCCCCHHHHHHCCCCHHHHHHHHHCCEEEECCCCCCHHHHHCCCHHHHHHHHHHHCCCC
REAIAQGAISWGEPVMETAITTVRNGRLIYRGKDAVRLSADATLEEAAALLWNAGALPPA
HHHHHHCCCCCCHHHHHHHHHHHHCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCCCCH
RAAELPSGGPTGKARALAFLAARAAQDTPSFARHPTSLAREGSELLAGFCTAVTGTTGRG
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCH
FFHQRLARHWGLSPGGTDLVRRALVLVADHELNPSTFAARVAASTGAPLAACALAGCATL
HHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
TGPLHGEASQRALIYLKRALEDGPETALAGLADSGEPIPATGHTLYPEGDPRAGALLRWM
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEECCCCCCCHHHHHEEC
KPGGDLKRAIRAAENHTGARANIDMALAALSVQLELPEDAPFLIFASGRMAGWIAHAIEQ
CCCHHHHHHHHHHHCCCCCCCCHHHEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHH
VSSGKTIRPRANYMED
HHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006016; 12397186 [H]