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The map label for this gene is cpg2 [H]

Identifier: 114797736

GI number: 114797736

Start: 2072846

End: 2074033

Strand: Reverse

Name: cpg2 [H]

Synonym: HNE_1997

Alternate gene names: 114797736

Gene position: 2074033-2072846 (Counterclockwise)

Preceding gene: 114800514

Following gene: 114798484

Centisome position: 55.98

GC content: 64.31

Gene sequence:

>1188_bases
ATGGTCACGCGCGCGCATGGCTGGTCCTCCATCAACACCGGCAGTTACAATATCGATGGCCTGAAGACGCTGGCCCCCAA
GCTGGCGGATGCATTCTCGGCGCTTGAGGCCGACGTCAACCTGGTCGAAGGCCCCGGCTTTGAAACGGTCGGCGCTGATG
GCCGGACGTCCGAAATGCACACCGGCCCGATCATCCAGGTCCAGTCGCGCCCCTCCGCGCCGATCCAGGTGGTTATGTCC
GGCCACTATGACACCGTCTTTCCGCCGGGCACGTTCGAGACCATCCGGGATCTTGGCAATGGCCAGATCAACGGGCCGGG
AATGGCCGACATGAAGGGAGGGCTGAGCCTGATGCTCGAAGCCCTCAAGGCATTCGAAGCTGGTCCGCTCAAGGATCGCC
TCGGCTACCGGATCGTCATGACGCCGGATGAGGAAATCGGAAACTTTGCAAGCGCCGGCGCTCTCACGGAAGCTGCCCGT
TCCGGCGCGCACATCGGCATGACCTATGAGCCCGCAATGGAGACGGGCGCCATGTCTGGCGGGCGCAAGGGCTCTGCCGT
GTTCGACATCGTGCTCCATGGCCGCGCCGCCCATGCCGGCCGTGCAAAAGAAGAAGGCCGCAGCGCTATCGAGGCGGCCG
CTGAGCTGGTGGTCGGCCTGGAAGGGCTGAACGGTCAGCGCGACGGCGTCACGTTCAATGTCGGTGCAATCGAAGGCGGC
GGACCGGTCAATATCGTGCCGGATCTGGCAGTTGTGCGGTTCGGTGCCCGTGCGCCCGATGCGGAGGCCTCAGCCTGGGC
AACCCAGCAGGTCGGCCGCCTCTTTGAACGCGCAACGGCGCGCAACGGCATTCACGGCCATCTGCATGGCGGCTTTTATC
GCCCACCCAAGCCTCGCAATACGGCGCAGCAGGCCCTGTTTGACGCGGTCCACGCAACCGGCTGCGCGATCGGCCTGGAC
CTGGAATTCGTCGATACGGGCGGGGTCTGTGAAGGCAACAATATTTTCGCGGCCGGGGTTCCGAATGTGGATACGCTCGG
CGTGCGCGGTGGCCGGATTCACTCAAATGAGGAGTTCGTCATCGTCGACAGTTTTGTGGAGCGCGCGACGCTCTCGGCGT
TGATCCTCAACCGGCTGGCGGACGGCCGGATGGATGGGAAGCGCATCAAGGACCTGATGGGGCGCTGA

Upstream 100 bases:

>100_bases
GTGGCTTCAGCTGTGAAACCAAGGGGCTATGAACCAACTCAGCTCTCTTACCCGCGAAGATGAGGCCGCTCGCGAGCGTC
TTGCCGCGGCCGCAACGGAT

Downstream 100 bases:

>100_bases
ATGACAACCGAATATGTGATGCGTCCTTCAAGGCTCGATGATCTCGAGGCCCTGATGGGGCTGGCGGAATTGTCCGGCCC
TGGATTTACCAGCTTGCCGG

Product: hypothetical protein

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MVTRAHGWSSINTGSYNIDGLKTLAPKLADAFSALEADVNLVEGPGFETVGADGRTSEMHTGPIIQVQSRPSAPIQVVMS
GHYDTVFPPGTFETIRDLGNGQINGPGMADMKGGLSLMLEALKAFEAGPLKDRLGYRIVMTPDEEIGNFASAGALTEAAR
SGAHIGMTYEPAMETGAMSGGRKGSAVFDIVLHGRAAHAGRAKEEGRSAIEAAAELVVGLEGLNGQRDGVTFNVGAIEGG
GPVNIVPDLAVVRFGARAPDAEASAWATQQVGRLFERATARNGIHGHLHGGFYRPPKPRNTAQQALFDAVHATGCAIGLD
LEFVDTGGVCEGNNIFAAGVPNVDTLGVRGGRIHSNEEFVIVDSFVERATLSALILNRLADGRMDGKRIKDLMGR

Sequences:

>Translated_395_residues
MVTRAHGWSSINTGSYNIDGLKTLAPKLADAFSALEADVNLVEGPGFETVGADGRTSEMHTGPIIQVQSRPSAPIQVVMS
GHYDTVFPPGTFETIRDLGNGQINGPGMADMKGGLSLMLEALKAFEAGPLKDRLGYRIVMTPDEEIGNFASAGALTEAAR
SGAHIGMTYEPAMETGAMSGGRKGSAVFDIVLHGRAAHAGRAKEEGRSAIEAAAELVVGLEGLNGQRDGVTFNVGAIEGG
GPVNIVPDLAVVRFGARAPDAEASAWATQQVGRLFERATARNGIHGHLHGGFYRPPKPRNTAQQALFDAVHATGCAIGLD
LEFVDTGGVCEGNNIFAAGVPNVDTLGVRGGRIHSNEEFVIVDSFVERATLSALILNRLADGRMDGKRIKDLMGR
>Mature_395_residues
MVTRAHGWSSINTGSYNIDGLKTLAPKLADAFSALEADVNLVEGPGFETVGADGRTSEMHTGPIIQVQSRPSAPIQVVMS
GHYDTVFPPGTFETIRDLGNGQINGPGMADMKGGLSLMLEALKAFEAGPLKDRLGYRIVMTPDEEIGNFASAGALTEAAR
SGAHIGMTYEPAMETGAMSGGRKGSAVFDIVLHGRAAHAGRAKEEGRSAIEAAAELVVGLEGLNGQRDGVTFNVGAIEGG
GPVNIVPDLAVVRFGARAPDAEASAWATQQVGRLFERATARNGIHGHLHGGFYRPPKPRNTAQQALFDAVHATGCAIGLD
LEFVDTGGVCEGNNIFAAGVPNVDTLGVRGGRIHSNEEFVIVDSFVERATLSALILNRLADGRMDGKRIKDLMGR

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 41409; Mature: 41409

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTRAHGWSSINTGSYNIDGLKTLAPKLADAFSALEADVNLVEGPGFETVGADGRTSEMH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCC
TGPIIQVQSRPSAPIQVVMSGHYDTVFPPGTFETIRDLGNGQINGPGMADMKGGLSLMLE
CCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHCCHHHHHH
ALKAFEAGPLKDRLGYRIVMTPDEEIGNFASAGALTEAARSGAHIGMTYEPAMETGAMSG
HHHHHCCCCCHHHCCEEEEECCCHHHCCHHHHHHHHHHHHCCCEECEEECCHHHHCCCCC
GRKGSAVFDIVLHGRAAHAGRAKEEGRSAIEAAAELVVGLEGLNGQRDGVTFNVGAIEGG
CCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCC
GPVNIVPDLAVVRFGARAPDAEASAWATQQVGRLFERATARNGIHGHLHGGFYRPPKPRN
CCCEECCCHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
TAQQALFDAVHATGCAIGLDLEFVDTGGVCEGNNIFAAGVPNVDTLGVRGGRIHSNEEFV
HHHHHHHHHHHHCCEEEEEEEEEECCCCEECCCCEEECCCCCCCEECCCCCEEECCCCEE
IVDSFVERATLSALILNRLADGRMDGKRIKDLMGR
EEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MVTRAHGWSSINTGSYNIDGLKTLAPKLADAFSALEADVNLVEGPGFETVGADGRTSEMH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCC
TGPIIQVQSRPSAPIQVVMSGHYDTVFPPGTFETIRDLGNGQINGPGMADMKGGLSLMLE
CCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHCCHHHHHH
ALKAFEAGPLKDRLGYRIVMTPDEEIGNFASAGALTEAARSGAHIGMTYEPAMETGAMSG
HHHHHCCCCCHHHCCEEEEECCCHHHCCHHHHHHHHHHHHCCCEECEEECCHHHHCCCCC
GRKGSAVFDIVLHGRAAHAGRAKEEGRSAIEAAAELVVGLEGLNGQRDGVTFNVGAIEGG
CCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCC
GPVNIVPDLAVVRFGARAPDAEASAWATQQVGRLFERATARNGIHGHLHGGFYRPPKPRN
CCCEECCCHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
TAQQALFDAVHATGCAIGLDLEFVDTGGVCEGNNIFAAGVPNVDTLGVRGGRIHSNEEFV
HHHHHHHHHHHHCCEEEEEEEEEECCCCEECCCCEEECCCCCCCEECCCCCEEECCCCEE
IVDSFVERATLSALILNRLADGRMDGKRIKDLMGR
EEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]