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The map label for this gene is qseB [H]

Identifier: 114797709

GI number: 114797709

Start: 1338783

End: 1339466

Strand: Direct

Name: qseB [H]

Synonym: HNE_1306

Alternate gene names: 114797709

Gene position: 1338783-1339466 (Clockwise)

Preceding gene: 114798361

Following gene: 114797185

Centisome position: 36.13

GC content: 63.45

Gene sequence:

>684_bases
ATGCGTATCCTGGTTGTTGAAGACGATGCAGACCTCCGCCGGCAGCTGGCCGATGTGCTGTCGCAGTCTGGCTACGCCGT
AGACCTGGCCGCCGACGGCGAGGATGGGCAATTCCTCGGCGAGACCGAGCCTTATGACGCTGTTGTGCTGGACCTTGGCC
TGCCCAAGATCGACGGGGTGAGCGTGCTGAAAAGCTGGCGCAAGGAGGGCAAGACCTTTCCGGTGCTGATCCTCACGGCC
CGCGATCAGTGGAGCGAGAAGGTGTCGGGCTTCGATGCCGGGGCCGATGATTACCTCACGAAGCCTTTCATCACCGAAGA
GCTGCTGGCGCGGTTGCGGGCGCTGCTGCGCCGGGCGGCGGGGCATTCGGCGGCGACGATCGAGTGCGGCAAGCTGATGG
TGGATACCCGCGCGGCGCGCGCGACGGTGAATGGCGAACCGATCAAGCTGACGGCGCATGAATACCGTGTTCTTTCCTAC
CTGATGCATCATCAGGGCCGGGTGGTGCCGCGCACGGAGCTGGTCGAGCATATTTACGATCAGGATTTCGACCGCGATTC
CAACACGATTGAGGTGTTCATCGGGCGCCTGCGGCGTAAGATCGGCCAGGACCGTATCCAGACCGAACGCGGCCTTGGCT
ATCGCCTGATCGTGCCAGAGGACGAAGCGCGCGTTGCGGGCTGA

Upstream 100 bases:

>100_bases
AGACGGCCGCAAGGCCCATTTCACCGTCGACGCGCAGAGCGGATCGGTGATGAACCGCCGCGGCGGTTAAGTCGTCTGAA
GCGTTTATTGGAGAAGAGAC

Downstream 100 bases:

>100_bases
TACCGAACGCGGCTAGATCGCCTCCATGAGTGAGGCCCCACACCCCAAACGTAGTTTGATTGACCGCTGGTCCAGCGTCT
CGCTGGCCCGGCGTGTCATG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MRILVVEDDADLRRQLADVLSQSGYAVDLAADGEDGQFLGETEPYDAVVLDLGLPKIDGVSVLKSWRKEGKTFPVLILTA
RDQWSEKVSGFDAGADDYLTKPFITEELLARLRALLRRAAGHSAATIECGKLMVDTRAARATVNGEPIKLTAHEYRVLSY
LMHHQGRVVPRTELVEHIYDQDFDRDSNTIEVFIGRLRRKIGQDRIQTERGLGYRLIVPEDEARVAG

Sequences:

>Translated_227_residues
MRILVVEDDADLRRQLADVLSQSGYAVDLAADGEDGQFLGETEPYDAVVLDLGLPKIDGVSVLKSWRKEGKTFPVLILTA
RDQWSEKVSGFDAGADDYLTKPFITEELLARLRALLRRAAGHSAATIECGKLMVDTRAARATVNGEPIKLTAHEYRVLSY
LMHHQGRVVPRTELVEHIYDQDFDRDSNTIEVFIGRLRRKIGQDRIQTERGLGYRLIVPEDEARVAG
>Mature_227_residues
MRILVVEDDADLRRQLADVLSQSGYAVDLAADGEDGQFLGETEPYDAVVLDLGLPKIDGVSVLKSWRKEGKTFPVLILTA
RDQWSEKVSGFDAGADDYLTKPFITEELLARLRALLRRAAGHSAATIECGKLMVDTRAARATVNGEPIKLTAHEYRVLSY
LMHHQGRVVPRTELVEHIYDQDFDRDSNTIEVFIGRLRRKIGQDRIQTERGLGYRLIVPEDEARVAG

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=216, Percent_Identity=44.4444444444444, Blast_Score=180, Evalue=5e-47,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=40.9691629955947, Blast_Score=174, Evalue=4e-45,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=41.743119266055, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=43.6936936936937, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=38.5650224215247, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=36.7713004484305, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=36.5638766519824, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=35.0649350649351, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=34.4978165938865, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=32.579185520362, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.0316742081448, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=30.8035714285714, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=30.4347826086957, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=25.764192139738, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=37.2549019607843, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1790299, Length=121, Percent_Identity=33.0578512396694, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=30.5785123966942, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25433; Mature: 25433

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVVEDDADLRRQLADVLSQSGYAVDLAADGEDGQFLGETEPYDAVVLDLGLPKIDGV
CEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCHH
SVLKSWRKEGKTFPVLILTARDQWSEKVSGFDAGADDYLTKPFITEELLARLRALLRRAA
HHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHC
GHSAATIECGKLMVDTRAARATVNGEPIKLTAHEYRVLSYLMHHQGRVVPRTELVEHIYD
CCCCEEEECCCEEEECHHHHEECCCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QDFDRDSNTIEVFIGRLRRKIGQDRIQTERGLGYRLIVPEDEARVAG
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MRILVVEDDADLRRQLADVLSQSGYAVDLAADGEDGQFLGETEPYDAVVLDLGLPKIDGV
CEEEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCHH
SVLKSWRKEGKTFPVLILTARDQWSEKVSGFDAGADDYLTKPFITEELLARLRALLRRAA
HHHHHHHHCCCCEEEEEEECCCHHHHHHCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHC
GHSAATIECGKLMVDTRAARATVNGEPIKLTAHEYRVLSYLMHHQGRVVPRTELVEHIYD
CCCCEEEECCCEEEECHHHHEECCCCCEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
QDFDRDSNTIEVFIGRLRRKIGQDRIQTERGLGYRLIVPEDEARVAG
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]