Click here to switch to the map view.

The map label for this gene is ycbU [H]

Identifier: 114797668

GI number: 114797668

Start: 1180860

End: 1182002

Strand: Reverse

Name: ycbU [H]

Synonym: HNE_1171

Alternate gene names: 114797668

Gene position: 1182002-1180860 (Counterclockwise)

Preceding gene: 114799981

Following gene: 114799566

Centisome position: 31.9

GC content: 65.79

Gene sequence:

>1143_bases
ATGACCCTGCTTCCAGACCAGCGCCACCTGTTCGACATCCCCGACGATGTCGCCTACCTCAACACCGCCACGATGGGCCC
GCTTCCCATCGCGGCCTTTGAGGCAGGCCAGCGCGGCCTTGCCCGCAAGCTGCGCCCCTGGACCATTCCGGATACGGAGT
TCTTTTCCGATACCGCCCGCCTGCGACCCCTCCTGGCCCAGCTCATCAATGCAGACGCAGACGGCATCGCCTTCGTCCCA
TCGGCCAGCTATGGCCTCGCCACCGCCGCGCTCAACCTGCCGCTGTCCCCCGGTCAGGAAATCCTGATCCTGGAGGACCA
GTTCCCGTCCAACGTCTACACATGGCGCGCCCATGCCGCCGCCACCGGCGCAACGCTGCGCACGGTGAAAGCGGGCGGCA
ACGAGTCCCTCTCCGAAGCTCTGCTCGACGCCATCGGCATGGCCACCGGCATCGTCGCGTGCCCGCATGTGCGCTGGACG
GATGGCGCGCGTCTCGATCTGTCCCGGATTGTCCGGAAATGTCGCGAGAATGGCGCCGCTCTGGTCCTTGATCTGACGCA
AAGCGCCGGCGCCCTGTCGTTCAATGCCAGCGAAATCGAGCCCGATTTCATGGTCGCCGCCGGCTATAAATGGCTGCTCG
GTCCCTATGCCACCGGCTTCCTCTATGTCGCCCCGAAACACCGCCAGGGCCGCCCGCTGGAGCAGAACTGGATCACCCGC
GAGAACGCCTCAAACTTCGCCCGCCTGATCGATTATACCGACGCCTACGCGCCCGGCGCCGAACGCTTCGATATGGGGGA
ACGGTCAAACTTTGCCCTCTTGCCCGCGCTGGAAGAGGCGGTGAAGCTGATCCTCCACTGGGGCATTACCAACATTGAAG
AAACGCTCGGCCATCGCAACCGCCAGCTCGCCGCGGACCTGGCCGAAATGGGCCTCTCAAGCCTGCCGGAAAGCGAGCGC
GGCCCGCATTACCTCTCCGCCCTCCTGCCCGCGTCCGCCCCGGATGATCTCACTGCCCGCCTCAGGGCCGAAAACATCCA
CGTCTCCCGCCGCGGCGACCGCCTGCGCATCACGCCCCACCTCTACACCAGCGACTACGACATCGCCCGCTTCCTGGCCG
CGCTCAAACGCCATCTCGGCTAG

Upstream 100 bases:

>100_bases
CCCCCGCGCGTTCCGGCCGCAACCGCTGCCAAAGCGCAAAACCCGCCCCAAAAGCGTCTTTCCACTGGCCTGCCCGGCTC
ACTCGCGTTAGCCCTTATGC

Downstream 100 bases:

>100_bases
ATCAGAGCAGCCAGCTCTCGGGATTCTCGACAAGCTCTCCTGCCGACAAGGCCTGAAGCCCCTTCACGATCCGCACGATG
TACCAGACCAGCGCCGCCAG

Product: class V aminotransferase

Products: hydrogen selenide; @ALAN01.txt*l-alanine!; acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTLLPDQRHLFDIPDDVAYLNTATMGPLPIAAFEAGQRGLARKLRPWTIPDTEFFSDTARLRPLLAQLINADADGIAFVP
SASYGLATAALNLPLSPGQEILILEDQFPSNVYTWRAHAAATGATLRTVKAGGNESLSEALLDAIGMATGIVACPHVRWT
DGARLDLSRIVRKCRENGAALVLDLTQSAGALSFNASEIEPDFMVAAGYKWLLGPYATGFLYVAPKHRQGRPLEQNWITR
ENASNFARLIDYTDAYAPGAERFDMGERSNFALLPALEEAVKLILHWGITNIEETLGHRNRQLAADLAEMGLSSLPESER
GPHYLSALLPASAPDDLTARLRAENIHVSRRGDRLRITPHLYTSDYDIARFLAALKRHLG

Sequences:

>Translated_380_residues
MTLLPDQRHLFDIPDDVAYLNTATMGPLPIAAFEAGQRGLARKLRPWTIPDTEFFSDTARLRPLLAQLINADADGIAFVP
SASYGLATAALNLPLSPGQEILILEDQFPSNVYTWRAHAAATGATLRTVKAGGNESLSEALLDAIGMATGIVACPHVRWT
DGARLDLSRIVRKCRENGAALVLDLTQSAGALSFNASEIEPDFMVAAGYKWLLGPYATGFLYVAPKHRQGRPLEQNWITR
ENASNFARLIDYTDAYAPGAERFDMGERSNFALLPALEEAVKLILHWGITNIEETLGHRNRQLAADLAEMGLSSLPESER
GPHYLSALLPASAPDDLTARLRAENIHVSRRGDRLRITPHLYTSDYDIARFLAALKRHLG
>Mature_379_residues
TLLPDQRHLFDIPDDVAYLNTATMGPLPIAAFEAGQRGLARKLRPWTIPDTEFFSDTARLRPLLAQLINADADGIAFVPS
ASYGLATAALNLPLSPGQEILILEDQFPSNVYTWRAHAAATGATLRTVKAGGNESLSEALLDAIGMATGIVACPHVRWTD
GARLDLSRIVRKCRENGAALVLDLTQSAGALSFNASEIEPDFMVAAGYKWLLGPYATGFLYVAPKHRQGRPLEQNWITRE
NASNFARLIDYTDAYAPGAERFDMGERSNFALLPALEEAVKLILHWGITNIEETLGHRNRQLAADLAEMGLSSLPESERG
PHYLSALLPASAPDDLTARLRAENIHVSRRGDRLRITPHLYTSDYDIARFLAALKRHLG

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.8.1.7 [C]

Molecular weight: Translated: 41646; Mature: 41515

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLPDQRHLFDIPDDVAYLNTATMGPLPIAAFEAGQRGLARKLRPWTIPDTEFFSDTAR
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHCHHHHHHHCCCCCCCCHHHHHHHHH
LRPLLAQLINADADGIAFVPSASYGLATAALNLPLSPGQEILILEDQFPSNVYTWRAHAA
HHHHHHHHHCCCCCCEEECCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEECHHH
ATGATLRTVKAGGNESLSEALLDAIGMATGIVACPHVRWTDGARLDLSRIVRKCRENGAA
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCE
LVLDLTQSAGALSFNASEIEPDFMVAAGYKWLLGPYATGFLYVAPKHRQGRPLEQNWITR
EEEEECCCCCEEEECCCCCCCCEEEECCCHHHHCCCCCCEEEECCCCCCCCCCHHHCCCC
ENASNFARLIDYTDAYAPGAERFDMGERSNFALLPALEEAVKLILHWGITNIEETLGHRN
CCHHHHHHHHHHHCCCCCCCHHCCCCCCCCEEECHHHHHHHHHHHHHCCCHHHHHHCCCH
RQLAADLAEMGLSSLPESERGPHYLSALLPASAPDDLTARLRAENIHVSRRGDRLRITPH
HHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHCEEEEECCCCEEEEEEE
LYTSDYDIARFLAALKRHLG
EECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLLPDQRHLFDIPDDVAYLNTATMGPLPIAAFEAGQRGLARKLRPWTIPDTEFFSDTAR
CCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHCHHHHHHHCCCCCCCCHHHHHHHHH
LRPLLAQLINADADGIAFVPSASYGLATAALNLPLSPGQEILILEDQFPSNVYTWRAHAA
HHHHHHHHHCCCCCCEEECCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCEEEEECHHH
ATGATLRTVKAGGNESLSEALLDAIGMATGIVACPHVRWTDGARLDLSRIVRKCRENGAA
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCE
LVLDLTQSAGALSFNASEIEPDFMVAAGYKWLLGPYATGFLYVAPKHRQGRPLEQNWITR
EEEEECCCCCEEEECCCCCCCCEEEECCCHHHHCCCCCCEEEECCCCCCCCCCHHHCCCC
ENASNFARLIDYTDAYAPGAERFDMGERSNFALLPALEEAVKLILHWGITNIEETLGHRN
CCHHHHHHHHHHHCCCCCCCHHCCCCCCCCEEECHHHHHHHHHHHHHCCCHHHHHHCCCH
RQLAADLAEMGLSSLPESERGPHYLSALLPASAPDDLTARLRAENIHVSRRGDRLRITPH
HHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHCEEEEECCCCEEEEEEE
LYTSDYDIARFLAALKRHLG
EECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal phosphate [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-selenocysteine; reduced acceptor [C]

Specific reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + @ALAN01.txt*l-alanine! + acceptor [C]

General reaction: Elimination of H2S or RSH [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 7704254; 1353026 [H]