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The map label for this gene is yafC [C]

Identifier: 114797657

GI number: 114797657

Start: 1525355

End: 1526254

Strand: Direct

Name: yafC [C]

Synonym: HNE_1494

Alternate gene names: 114797657

Gene position: 1525355-1526254 (Clockwise)

Preceding gene: 114800459

Following gene: 114799531

Centisome position: 41.17

GC content: 63.67

Gene sequence:

>900_bases
ATGCCGGAACCCGCGCCTGTTGACCTGCTGGATGTGACCTCGTTCGTTCGGGTTGTGGAAACCGGCAGTATTGCCAATGC
AGCGGCACGCCTCGGCATCGCCAAGTCAATCGTAAGCCGCCGGGTCAGCCGCCTCGAGGCGGTGCTCGGCGCTCAGTTGC
TGACCCGGACTCCCAAGGGCACGACGCCAACAGATATCGGCCGGGAATATTACGCCCGCGCCGAGGCGGGCCTGATGGAA
CTTGAGTCGGCTCAGGAGGTCGTCAGCAAGCTGACGGGCGAGGTTTCAGGGCTTCTTCGCGTCCAGGTCCAGACGGCCTT
TGGCGAATTCGTGTTCGCGCCTTTGCTTGCAGAGTTTGCCCGGCTCCATCCGCAGGTTCAGTTCGATATCCGGTTCGAGG
ACCGTCAGGTAAACATGACCGATGAGGCCTATGATGTCGCGATCTGGCCTGGCCCCGCCTCGGACCCGATGCTTGTCACC
CGGAAAATTGCCGGGATCCGGTGGGCTGTTGTCGCCAGCCCGGCCTACCTCGATGCGCGAGGGCGTCCGGCGACGCCGGC
TGACCTGTCAGCCCACGACGCCCTGCTGCACGGTCTGGATTCCGGTATCTGGCACCTGCAAGGTTCAGATGGCTGGGAGC
ATGTGCGCATGAACTCCCGATTCCGTGCTGACAACGGCCATATGTTGCTGACCGCGGCGCGCGCGGATCTGGGCCTGGCC
CTGGTCCCGATGTTTATGGTCGAGGAGCTGTTGGGGCAGGGGGAACTGGAGGCGGTCCTGCCTGCATTCCCGCACGCCTG
GCCCGATCTGCACATCTTCATGCCGCCCCAGCGCGCTGGCATCGCGAGAGTGCGTGCCCTCGTGAAGTTCCTGTATCAAA
AGCTGGATGGGGAGGTGTGA

Upstream 100 bases:

>100_bases
TTGACGCGAGCGTGCAGCGGATGTTTCTGCAAACCTTTCACCGGAAATACCCATTCGGTAGTTTTGCAGTAGCCGCTAAA
GATGAGACTGGGAGTTGCTG

Downstream 100 bases:

>100_bases
GCGGGGGGCTGCCACGTGACCGCGAAGCGCAGACCGATGCATTCGTCGGCTACTCCATCATCAGCGCTATCACGAGGACC
TGAGAAACCTAACCCTCAAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MPEPAPVDLLDVTSFVRVVETGSIANAAARLGIAKSIVSRRVSRLEAVLGAQLLTRTPKGTTPTDIGREYYARAEAGLME
LESAQEVVSKLTGEVSGLLRVQVQTAFGEFVFAPLLAEFARLHPQVQFDIRFEDRQVNMTDEAYDVAIWPGPASDPMLVT
RKIAGIRWAVVASPAYLDARGRPATPADLSAHDALLHGLDSGIWHLQGSDGWEHVRMNSRFRADNGHMLLTAARADLGLA
LVPMFMVEELLGQGELEAVLPAFPHAWPDLHIFMPPQRAGIARVRALVKFLYQKLDGEV

Sequences:

>Translated_299_residues
MPEPAPVDLLDVTSFVRVVETGSIANAAARLGIAKSIVSRRVSRLEAVLGAQLLTRTPKGTTPTDIGREYYARAEAGLME
LESAQEVVSKLTGEVSGLLRVQVQTAFGEFVFAPLLAEFARLHPQVQFDIRFEDRQVNMTDEAYDVAIWPGPASDPMLVT
RKIAGIRWAVVASPAYLDARGRPATPADLSAHDALLHGLDSGIWHLQGSDGWEHVRMNSRFRADNGHMLLTAARADLGLA
LVPMFMVEELLGQGELEAVLPAFPHAWPDLHIFMPPQRAGIARVRALVKFLYQKLDGEV
>Mature_298_residues
PEPAPVDLLDVTSFVRVVETGSIANAAARLGIAKSIVSRRVSRLEAVLGAQLLTRTPKGTTPTDIGREYYARAEAGLMEL
ESAQEVVSKLTGEVSGLLRVQVQTAFGEFVFAPLLAEFARLHPQVQFDIRFEDRQVNMTDEAYDVAIWPGPASDPMLVTR
KIAGIRWAVVASPAYLDARGRPATPADLSAHDALLHGLDSGIWHLQGSDGWEHVRMNSRFRADNGHMLLTAARADLGLAL
VPMFMVEELLGQGELEAVLPAFPHAWPDLHIFMPPQRAGIARVRALVKFLYQKLDGEV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=283, Percent_Identity=29.6819787985866, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI145693193, Length=281, Percent_Identity=28.1138790035587, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=25.3521126760563, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787589, Length=276, Percent_Identity=28.6231884057971, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=28.8194444444444, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789639, Length=254, Percent_Identity=28.3464566929134, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=21.602787456446, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788706, Length=245, Percent_Identity=27.7551020408163, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787601, Length=177, Percent_Identity=28.8135593220339, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788481, Length=262, Percent_Identity=25.5725190839695, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789173, Length=237, Percent_Identity=26.5822784810127, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788297, Length=113, Percent_Identity=38.9380530973451, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32734; Mature: 32603

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEPAPVDLLDVTSFVRVVETGSIANAAARLGIAKSIVSRRVSRLEAVLGAQLLTRTPKG
CCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TTPTDIGREYYARAEAGLMELESAQEVVSKLTGEVSGLLRVQVQTAFGEFVFAPLLAEFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHH
RLHPQVQFDIRFEDRQVNMTDEAYDVAIWPGPASDPMLVTRKIAGIRWAVVASPAYLDAR
HHCCCEEEEEEEECCEECCCCCCEEEEECCCCCCCCCHHHHHHCCEEEEEEECCCEECCC
GRPATPADLSAHDALLHGLDSGIWHLQGSDGWEHVRMNSRFRADNGHMLLTAARADLGLA
CCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEECCCEEECCCCCEEEEECCCCCCHH
LVPMFMVEELLGQGELEAVLPAFPHAWPDLHIFMPPQRAGIARVRALVKFLYQKLDGEV
HHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PEPAPVDLLDVTSFVRVVETGSIANAAARLGIAKSIVSRRVSRLEAVLGAQLLTRTPKG
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TTPTDIGREYYARAEAGLMELESAQEVVSKLTGEVSGLLRVQVQTAFGEFVFAPLLAEFA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHH
RLHPQVQFDIRFEDRQVNMTDEAYDVAIWPGPASDPMLVTRKIAGIRWAVVASPAYLDAR
HHCCCEEEEEEEECCEECCCCCCEEEEECCCCCCCCCHHHHHHCCEEEEEEECCCEECCC
GRPATPADLSAHDALLHGLDSGIWHLQGSDGWEHVRMNSRFRADNGHMLLTAARADLGLA
CCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEECCCEEECCCCCEEEEECCCCCCHH
LVPMFMVEELLGQGELEAVLPAFPHAWPDLHIFMPPQRAGIARVRALVKFLYQKLDGEV
HHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]