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The map label for this gene is ybdR [H]

Identifier: 114797612

GI number: 114797612

Start: 2958275

End: 2959318

Strand: Direct

Name: ybdR [H]

Synonym: HNE_2796

Alternate gene names: 114797612

Gene position: 2958275-2959318 (Clockwise)

Preceding gene: 114798453

Following gene: 114800014

Centisome position: 79.85

GC content: 65.04

Gene sequence:

>1044_bases
ATGAAAGCTCTCGTTTATCGCGGCCCGCGCGACATCGCCTTTGAAACGATGAAAGACCCCGACCTGCACGATGACCGCGA
CGCGATCATCAAGGTCGACAAATGCGCCATCTGCGGCAGCGACCTGCACATCTATCATGGCGAAACCTTCTCCGAGGACA
CCGGCTATTGTGTCGGCCATGAAGCCGTCGGCGAGGTGGTCGAAATCGGCCGCGGCGTGCGCCAGCTGAAAGTGGGCGAC
AAGGTGATGATCTCGGCGGCGGTCGGGTGCGGCCAGTGCCGCGCCTGTCTCGCCGGGGTCGTCAACCGCTGCGAATTCAA
TGCCGGCAGCTGCTATGGCCTCTCGGCAAAACTGCAAGGCTGCCAGGCCGAAGCCGTCCGTGTCCCCGCCGCTGACTTCA
ACGCCCAGAAGATCCCAGACGGCATCAGCCTCGACCAGGCCCTGATGATGACCGACGCCCTCGCCACCGCCTGGTTCGGC
GCGCGCAACGCGGATATTCAGCGCGGCGCCACCGTCGCCGTCGTCGGCCTCGGCCCCATCGGTCTATTGGCTGCGGAAGC
CGCCTTCATCATGGGCGCCTCCCGCGTCTTCGGTATCGACCTTGTGGAGGAACGCCGCGCGGCGGGCCGCGCCATCGGCC
TTGAAACGCCAGACCCGGCGGATGCCCGCGCCATCATCCAGGAGGCCACAAAGGGCCGCATGTGCGACAGCGTCATCGAA
GCGGTCGGCCACTCGGCCACCATCCGCGCCGCCCTCGGCCTTTCGGGCAAGCGCGCCACGGTCTCGGTCGTCGGCGTCGC
TCAGGACCGCACCTTCGACTTCCCGATGTCAAAAGCCTTCGGCATGGGCCTCACCTTCCGTATCGGGACATGTTCGGTCC
CCCAGGAATGGCCCGAGCTGATCCCGCTCGTCCAATCCGGCCGCATCAAGCCGGAAAAATACATCACTCACACCCTCCCC
CTGTCAGACGGCGCCCGCGCCTACGACATCTTCGACAAACGCACCGAAGGCGCGATGAAGATGGTGTTTGACCTGACGCT
TTGA

Upstream 100 bases:

>100_bases
TGGTCCGGACGAAGTCCACATGTCCCAGCTCGGCAAGCTGAAAATCCAGGAATATAACGCCCTTCCGGTCCGCTGATCTG
TCCGCTCAAGGAGAAACGCC

Downstream 100 bases:

>100_bases
TCCCGGCGCCAACAAAATCTCACCAAACATTGCCAGACCGGCCCCTTCATGTTCAGTAGTGATAACTATCGAACATGAAG
GGGCTGCGCCCATGCCAGAC

Product: class III alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKALVYRGPRDIAFETMKDPDLHDDRDAIIKVDKCAICGSDLHIYHGETFSEDTGYCVGHEAVGEVVEIGRGVRQLKVGD
KVMISAAVGCGQCRACLAGVVNRCEFNAGSCYGLSAKLQGCQAEAVRVPAADFNAQKIPDGISLDQALMMTDALATAWFG
ARNADIQRGATVAVVGLGPIGLLAAEAAFIMGASRVFGIDLVEERRAAGRAIGLETPDPADARAIIQEATKGRMCDSVIE
AVGHSATIRAALGLSGKRATVSVVGVAQDRTFDFPMSKAFGMGLTFRIGTCSVPQEWPELIPLVQSGRIKPEKYITHTLP
LSDGARAYDIFDKRTEGAMKMVFDLTL

Sequences:

>Translated_347_residues
MKALVYRGPRDIAFETMKDPDLHDDRDAIIKVDKCAICGSDLHIYHGETFSEDTGYCVGHEAVGEVVEIGRGVRQLKVGD
KVMISAAVGCGQCRACLAGVVNRCEFNAGSCYGLSAKLQGCQAEAVRVPAADFNAQKIPDGISLDQALMMTDALATAWFG
ARNADIQRGATVAVVGLGPIGLLAAEAAFIMGASRVFGIDLVEERRAAGRAIGLETPDPADARAIIQEATKGRMCDSVIE
AVGHSATIRAALGLSGKRATVSVVGVAQDRTFDFPMSKAFGMGLTFRIGTCSVPQEWPELIPLVQSGRIKPEKYITHTLP
LSDGARAYDIFDKRTEGAMKMVFDLTL
>Mature_347_residues
MKALVYRGPRDIAFETMKDPDLHDDRDAIIKVDKCAICGSDLHIYHGETFSEDTGYCVGHEAVGEVVEIGRGVRQLKVGD
KVMISAAVGCGQCRACLAGVVNRCEFNAGSCYGLSAKLQGCQAEAVRVPAADFNAQKIPDGISLDQALMMTDALATAWFG
ARNADIQRGATVAVVGLGPIGLLAAEAAFIMGASRVFGIDLVEERRAAGRAIGLETPDPADARAIIQEATKGRMCDSVIE
AVGHSATIRAALGLSGKRATVSVVGVAQDRTFDFPMSKAFGMGLTFRIGTCSVPQEWPELIPLVQSGRIKPEKYITHTLP
LSDGARAYDIFDKRTEGAMKMVFDLTL

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily [H]

Homologues:

Organism=Homo sapiens, GI71565152, Length=354, Percent_Identity=27.9661016949153, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI156627571, Length=360, Percent_Identity=25, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI71565154, Length=360, Percent_Identity=25, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4501929, Length=351, Percent_Identity=27.3504273504274, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4501939, Length=333, Percent_Identity=25.5255255255255, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI156523966, Length=333, Percent_Identity=25.5255255255255, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI34577061, Length=329, Percent_Identity=26.7477203647416, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI4501933, Length=349, Percent_Identity=26.0744985673352, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI71743840, Length=333, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI262073058, Length=333, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786825, Length=386, Percent_Identity=37.0466321243523, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI1790045, Length=353, Percent_Identity=31.1614730878187, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI226510992, Length=342, Percent_Identity=28.3625730994152, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788073, Length=325, Percent_Identity=28, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1787863, Length=354, Percent_Identity=26.5536723163842, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87082125, Length=324, Percent_Identity=26.8518518518519, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790718, Length=326, Percent_Identity=24.2331288343558, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788075, Length=361, Percent_Identity=25.4847645429363, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081918, Length=226, Percent_Identity=30.9734513274336, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788407, Length=315, Percent_Identity=25.0793650793651, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1786552, Length=338, Percent_Identity=25.1479289940828, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=355, Percent_Identity=27.3239436619718, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17562878, Length=191, Percent_Identity=33.5078534031414, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25146526, Length=365, Percent_Identity=24.3835616438356, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997431, Length=365, Percent_Identity=24.1095890410959, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17565904, Length=330, Percent_Identity=23.9393939393939, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=266, Percent_Identity=25.5639097744361, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=338, Percent_Identity=27.2189349112426, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6319955, Length=340, Percent_Identity=26.7647058823529, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322619, Length=340, Percent_Identity=26.7647058823529, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319257, Length=360, Percent_Identity=26.1111111111111, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6319258, Length=247, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320033, Length=365, Percent_Identity=27.3972602739726, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323729, Length=237, Percent_Identity=29.1139240506329, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319621, Length=249, Percent_Identity=28.5140562248996, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=194, Percent_Identity=31.9587628865979, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137530, Length=350, Percent_Identity=27.4285714285714, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17737897, Length=350, Percent_Identity=28, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17737895, Length=363, Percent_Identity=25.3443526170799, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI221457811, Length=348, Percent_Identity=27.0114942528736, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI45551930, Length=348, Percent_Identity=27.0114942528736, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI45550770, Length=348, Percent_Identity=27.0114942528736, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 36971; Mature: 36971

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVYRGPRDIAFETMKDPDLHDDRDAIIKVDKCAICGSDLHIYHGETFSEDTGYCVGH
CCCEEECCCCCCEECCCCCCCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCCCCEEECH
EAVGEVVEIGRGVRQLKVGDKVMISAAVGCGQCRACLAGVVNRCEFNAGSCYGLSAKLQG
HHHHHHHHHCCCHHEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEECHHHCCC
CQAEAVRVPAADFNAQKIPDGISLDQALMMTDALATAWFGARNADIQRGATVAVVGLGPI
CCCCEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCH
GLLAAEAAFIMGASRVFGIDLVEERRAAGRAIGLETPDPADARAIIQEATKGRMCDSVIE
HHHHHHHHHHHCCCHHEECHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHCCHHHHHHHH
AVGHSATIRAALGLSGKRATVSVVGVAQDRTFDFPMSKAFGMGLTFRIGTCSVPQEWPEL
HHCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCHHHHCCCEEEEECCCCCCHHHHHH
IPLVQSGRIKPEKYITHTLPLSDGARAYDIFDKRTEGAMKMVFDLTL
HHHHHCCCCCHHHHEEEEECCCCCCCEEHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MKALVYRGPRDIAFETMKDPDLHDDRDAIIKVDKCAICGSDLHIYHGETFSEDTGYCVGH
CCCEEECCCCCCEECCCCCCCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCCCCEEECH
EAVGEVVEIGRGVRQLKVGDKVMISAAVGCGQCRACLAGVVNRCEFNAGSCYGLSAKLQG
HHHHHHHHHCCCHHEEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEECHHHCCC
CQAEAVRVPAADFNAQKIPDGISLDQALMMTDALATAWFGARNADIQRGATVAVVGLGPI
CCCCEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCH
GLLAAEAAFIMGASRVFGIDLVEERRAAGRAIGLETPDPADARAIIQEATKGRMCDSVIE
HHHHHHHHHHHCCCHHEECHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHCCHHHHHHHH
AVGHSATIRAALGLSGKRATVSVVGVAQDRTFDFPMSKAFGMGLTFRIGTCSVPQEWPEL
HHCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCHHHHCCCEEEEECCCCCCHHHHHH
IPLVQSGRIKPEKYITHTLPLSDGARAYDIFDKRTEGAMKMVFDLTL
HHHHHCCCCCHHHHEEEEECCCCCCCEEHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]