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The map label for this gene is insK [C]

Identifier: 114797579

GI number: 114797579

Start: 532986

End: 533891

Strand: Reverse

Name: insK [C]

Synonym: HNE_0538

Alternate gene names: 114797579

Gene position: 533891-532986 (Counterclockwise)

Preceding gene: 114799153

Following gene: 114799514

Centisome position: 14.41

GC content: 61.59

Gene sequence:

>906_bases
ATGATCGCGTTCATTGACGACCATCGCGATGTTTATGGGGTCGAGCCGATCTGCAGGGTATTGCCGATTGCCCCATCAAC
CTTTCATGAGGCGGATGCGCGGCGGCGGCGCCCCGACCGCAGGCCGCCGCGCATCCGCCGGGACGAGACGCTGAAGCCGG
AGATCCTTCGGGTCTTCAACGAGAACTTCACCGTCTATGGCGCTAACAAGGTCTGGCACCAGATGAAGCGGGAAGGCTTT
GACGTGGCCCGCTGCACCGTCAGGCGCCTGATGAAGGCCATGGGTCTGAAGGGCATTATCCGCGGCAAGCCGCATCGCAC
GACCTACAGCGACAAGGTAGCGCCGTGCCCGCTCGACCATGTGAAGCGCAACTTCAAGGCTCCGGCGCCGAACCGGCTCT
GGGTCAGCGATTTCACCTACGTCTCGACCTGGGCTGGATTTGTCTACGTCGCCTTCGTCATTGATGTGTTCGCCCGCCGC
ATTGTCGGCTGGCGGGTCAGCCGGACAGCGCATGCGCGCTTTGTACTCGATGCTCTTGAGCAGGCCCTGCATGACCGGCG
GCCGGGCATCGGCAGCGGACTTGTTCATCACTCGGATCGTGGCAGCCAGTATGTCAGCATACGGTATACGGAGCGTCTGG
CGGAGGCAGGCCTCGAGCCGTCGGTCGGCAGTGTCGGCGATAGTTATGACAACGCCCTCGCCGAGACGATCAATGGACTC
TACAAGGCCGAAGTCATCTGGCGGAAAGGCCCTTGGAAATCCATGGACGCCGTCGAATACGCCACGCTCGAGTGGGTCGA
CTGGTTCAATCACCGCCGCCTGCTCGAGCCGATCGGAAACATCCCTCCGGCAGAAGCCGAGGCCAATTACTTTGCAGCCC
TAAAGGAAAACGCTACCGCTGCATGA

Upstream 100 bases:

>100_bases
CGCTTGAACGCGAGAACCGGGAGCTTCGCCAGGCGAACGAGATCCTCCGGAAGGCATCAGCGTATTTTGCTCAGGCGGAG
CTCGACCGCCGACCGAAGAC

Downstream 100 bases:

>100_bases
CTCCAACCAAACAGCCTCCGGGGTTACCGGCGCGGTTCAAGCAAGCGCAACCGGACAACCGTATATACAACATTCTGGCG
CTGCTTGCCCGCCTTGTGGT

Product: ISHne1, transposase orfB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIAFIDDHRDVYGVEPICRVLPIAPSTFHEADARRRRPDRRPPRIRRDETLKPEILRVFNENFTVYGANKVWHQMKREGF
DVARCTVRRLMKAMGLKGIIRGKPHRTTYSDKVAPCPLDHVKRNFKAPAPNRLWVSDFTYVSTWAGFVYVAFVIDVFARR
IVGWRVSRTAHARFVLDALEQALHDRRPGIGSGLVHHSDRGSQYVSIRYTERLAEAGLEPSVGSVGDSYDNALAETINGL
YKAEVIWRKGPWKSMDAVEYATLEWVDWFNHRRLLEPIGNIPPAEAEANYFAALKENATAA

Sequences:

>Translated_301_residues
MIAFIDDHRDVYGVEPICRVLPIAPSTFHEADARRRRPDRRPPRIRRDETLKPEILRVFNENFTVYGANKVWHQMKREGF
DVARCTVRRLMKAMGLKGIIRGKPHRTTYSDKVAPCPLDHVKRNFKAPAPNRLWVSDFTYVSTWAGFVYVAFVIDVFARR
IVGWRVSRTAHARFVLDALEQALHDRRPGIGSGLVHHSDRGSQYVSIRYTERLAEAGLEPSVGSVGDSYDNALAETINGL
YKAEVIWRKGPWKSMDAVEYATLEWVDWFNHRRLLEPIGNIPPAEAEANYFAALKENATAA
>Mature_301_residues
MIAFIDDHRDVYGVEPICRVLPIAPSTFHEADARRRRPDRRPPRIRRDETLKPEILRVFNENFTVYGANKVWHQMKREGF
DVARCTVRRLMKAMGLKGIIRGKPHRTTYSDKVAPCPLDHVKRNFKAPAPNRLWVSDFTYVSTWAGFVYVAFVIDVFARR
IVGWRVSRTAHARFVLDALEQALHDRRPGIGSGLVHHSDRGSQYVSIRYTERLAEAGLEPSVGSVGDSYDNALAETINGL
YKAEVIWRKGPWKSMDAVEYATLEWVDWFNHRRLLEPIGNIPPAEAEANYFAALKENATAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=253, Percent_Identity=54.5454545454545, Blast_Score=272, Evalue=2e-73,
Organism=Escherichia coli, GI1789981, Length=284, Percent_Identity=27.8169014084507, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788405, Length=244, Percent_Identity=30.327868852459, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787263, Length=244, Percent_Identity=30.327868852459, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1786753, Length=244, Percent_Identity=30.327868852459, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1786570, Length=244, Percent_Identity=30.327868852459, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1786490, Length=244, Percent_Identity=30.327868852459, Blast_Score=118, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 34443; Mature: 34443

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAFIDDHRDVYGVEPICRVLPIAPSTFHEADARRRRPDRRPPRIRRDETLKPEILRVFN
CEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHC
ENFTVYGANKVWHQMKREGFDVARCTVRRLMKAMGLKGIIRGKPHRTTYSDKVAPCPLDH
CCEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCHHH
VKRNFKAPAPNRLWVSDFTYVSTWAGFVYVAFVIDVFARRIVGWRVSRTAHARFVLDALE
HHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
QALHDRRPGIGSGLVHHSDRGSQYVSIRYTERLAEAGLEPSVGSVGDSYDNALAETINGL
HHHHHCCCCCCCCCEEECCCCCEEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
YKAEVIWRKGPWKSMDAVEYATLEWVDWFNHRRLLEPIGNIPPAEAEANYFAALKENATA
HHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCC
A
C
>Mature Secondary Structure
MIAFIDDHRDVYGVEPICRVLPIAPSTFHEADARRRRPDRRPPRIRRDETLKPEILRVFN
CEEEEECCCCCCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHC
ENFTVYGANKVWHQMKREGFDVARCTVRRLMKAMGLKGIIRGKPHRTTYSDKVAPCPLDH
CCEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCHHH
VKRNFKAPAPNRLWVSDFTYVSTWAGFVYVAFVIDVFARRIVGWRVSRTAHARFVLDALE
HHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
QALHDRRPGIGSGLVHHSDRGSQYVSIRYTERLAEAGLEPSVGSVGDSYDNALAETINGL
HHHHHCCCCCCCCCEEECCCCCEEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
YKAEVIWRKGPWKSMDAVEYATLEWVDWFNHRRLLEPIGNIPPAEAEANYFAALKENATA
HHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]