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The map label for this gene is bioD [H]

Identifier: 114797529

GI number: 114797529

Start: 1273359

End: 1274027

Strand: Direct

Name: bioD [H]

Synonym: HNE_1249

Alternate gene names: 114797529

Gene position: 1273359-1274027 (Clockwise)

Preceding gene: 114798527

Following gene: 114798460

Centisome position: 34.37

GC content: 60.69

Gene sequence:

>669_bases
ATGCGCAGTTACTTTGTAACGGCAACCGGCACCGACATTGGCAAGACATATGTCAGTGCCCGGCTGATTTCAGCCTGGCG
GGCGCAGGGTTATGTCGCGCAGGCGACAAAGCCGGTGATGAGTGGCTTTGCCGAGGACGCGCTGGAACAGTCCGACGCCG
GACGGCTGCTCACGGCGATGGGGCGGGCTGTGACACCCGCGTCAGTTGCCGAAATCTGTCTGCACCGGCTGGCGCCGCCG
CTGTCGCCGAATGTGGCGATGCGGCAGGCGGGGGTGCGCCAGGACTATCCGGAGATACTGGCATTTGTCCGGGATCGCCT
GTCGGACGGCGGGGACTGCCATCTGGTTGAGGGAGCGGGAGGCGTGATGTCTCCGTTGACGGATGAAAAACTGCAGATTG
ACCTGATGGCAGATTTGCAATTGCCAATCATTCTTATTACGGCGGCGTATCTGGGCTCGGTCAGCCATACGTTGACAGCG
TTGTATGCGCTGTCTGCGCGCGGCCTGAAGGTTTCTGCGGTGGCGATTTCACAGCCATTTTCATCCGGAGATGACCTCTC
GGCGTTTGCGGGAGAGCTTAATCGATTCAGGGACGTACCCGTATTCGGGATTCCGCACGGGCATGACGCAGCGGCGCTGG
GAACCGCGCTGTTGCAACAGGATGCGTAA

Upstream 100 bases:

>100_bases
CGGCGGGCACCGCGCGGCTGCGAGTGACGTTTGCCGCCGGACATGAGGAGGCGGACGTGCGCGCCTTTGCCGGGGCGCTG
AAAGAGATCATGGAGCTGGC

Downstream 100 bases:

>100_bases
TATTTTCTTCTCTTTGTATTTGAACTTCTGCCCACTTTGCGTATTGTAATACGTAGAATCCCTTAGTGATTGGATTGGGT
TTGGGATCACTCAGGGCGAA

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MRSYFVTATGTDIGKTYVSARLISAWRAQGYVAQATKPVMSGFAEDALEQSDAGRLLTAMGRAVTPASVAEICLHRLAPP
LSPNVAMRQAGVRQDYPEILAFVRDRLSDGGDCHLVEGAGGVMSPLTDEKLQIDLMADLQLPIILITAAYLGSVSHTLTA
LYALSARGLKVSAVAISQPFSSGDDLSAFAGELNRFRDVPVFGIPHGHDAAALGTALLQQDA

Sequences:

>Translated_222_residues
MRSYFVTATGTDIGKTYVSARLISAWRAQGYVAQATKPVMSGFAEDALEQSDAGRLLTAMGRAVTPASVAEICLHRLAPP
LSPNVAMRQAGVRQDYPEILAFVRDRLSDGGDCHLVEGAGGVMSPLTDEKLQIDLMADLQLPIILITAAYLGSVSHTLTA
LYALSARGLKVSAVAISQPFSSGDDLSAFAGELNRFRDVPVFGIPHGHDAAALGTALLQQDA
>Mature_222_residues
MRSYFVTATGTDIGKTYVSARLISAWRAQGYVAQATKPVMSGFAEDALEQSDAGRLLTAMGRAVTPASVAEICLHRLAPP
LSPNVAMRQAGVRQDYPEILAFVRDRLSDGGDCHLVEGAGGVMSPLTDEKLQIDLMADLQLPIILITAAYLGSVSHTLTA
LYALSARGLKVSAVAISQPFSSGDDLSAFAGELNRFRDVPVFGIPHGHDAAALGTALLQQDA

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=204, Percent_Identity=30.3921568627451, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 23427; Mature: 23427

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSYFVTATGTDIGKTYVSARLISAWRAQGYVAQATKPVMSGFAEDALEQSDAGRLLTAM
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GRAVTPASVAEICLHRLAPPLSPNVAMRQAGVRQDYPEILAFVRDRLSDGGDCHLVEGAG
CCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
GVMSPLTDEKLQIDLMADLQLPIILITAAYLGSVSHTLTALYALSARGLKVSAVAISQPF
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCC
SSGDDLSAFAGELNRFRDVPVFGIPHGHDAAALGTALLQQDA
CCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRSYFVTATGTDIGKTYVSARLISAWRAQGYVAQATKPVMSGFAEDALEQSDAGRLLTAM
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GRAVTPASVAEICLHRLAPPLSPNVAMRQAGVRQDYPEILAFVRDRLSDGGDCHLVEGAG
CCCCCHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
GVMSPLTDEKLQIDLMADLQLPIILITAAYLGSVSHTLTALYALSARGLKVSAVAISQPF
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCC
SSGDDLSAFAGELNRFRDVPVFGIPHGHDAAALGTALLQQDA
CCCCCHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA