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The map label for this gene is pksE [H]

Identifier: 114797459

GI number: 114797459

Start: 1864443

End: 1865981

Strand: Direct

Name: pksE [H]

Synonym: HNE_1818

Alternate gene names: 114797459

Gene position: 1864443-1865981 (Clockwise)

Preceding gene: 114799320

Following gene: 114799051

Centisome position: 50.32

GC content: 64.85

Gene sequence:

>1539_bases
TTGTTGGATTTGATACGGAAAGCCGTAGAGGCGCCGCGCGCGCGCGCCTGGATTTCGATCCCCGAATCCGGCATTCCAGA
ACTCGTTTCCGTTGGCGCTCAGCCCTCTGGCAATGCCTCTGCCGCGGCCCTTCCTCCTGTCTATCCAGAGTGGTTGGGTG
ACCGTGCTTTCGCTGCCGAACACGGCGCCCGTTTCAACTATGTTGCTGGCGAAATGGCCCGTGGAATTGCAACGCCTAAA
ATGGTTATCGAAGCGGCCCGCGCCGGCTGTGTCGGCTTCTATGGAAGCGCCGGCCTGCCCCTCGCCGAGATCAAATCAGG
CGTAGAGGAAATCAAGGCCGCCCTTGGCCCCGAAGCCCGAAACTGGGGCGCCAATCTCATCCACTCGCCGCAAGAGCCCG
GCCAGGAAAAAGCGGTAATCGACCTCTTCCTGTCCCAGGCCGTCTCAAGAGTGTCAGCGTCCGCCTTCATGCGCCTCACC
GCAGATGTCGTGCGCTATACAGCGCTCGGGCTCACCCGCGCCGCAGACGGCACCATCCAGCGCGCCAACCACATCTTCGC
CAAAGTCTCCCGCGCCGAAGTCGCCGAAGCCTTCATGGCGCCTGCCCCTGAAAAGATCCTGAAAGATCTCGTCGCAGAAG
GTGCGATCACCGCGCAGCAGGCAGACCTAGCCAGCAAGGTGCCCGTTGCAGCCGAAATCACCGCCGAATCGGACTCCGGC
GGCCACACGGACAATCGGCCCGCCTCCACCCTCTTCAGCTCCCTCGCCGCCGCACGCTCTCGGGTCGCCGCCCACAATGG
CCACCCGGAAAGCAGCATCCGCATCGGCCTCGCCGGCGGCATCGCCACGCCGCAATCGGTCGCCGCCGCCTTCCAGATGG
GCGCTGCCTATGTCCTGACCGGCTCCATCAATCAAAGCGCCATCGAATCCGGCCTTGCCGCGCCGGGCCGCGCGCTGCTG
GCGAAGGCAGGCCCGGCAGATGTCGCCATGACGCCAGCCGCCGACATGTTCGAACAAGGCGTGCAGGTACAAGTGCTCAA
ACGCGGCACGCTCTTCGCCATGCGCGGCAAGAAGTTCCACGCCTTCTATCGCAGCGGCGCCTCTTATGAGACCCTGCCCC
CAACGGATCAGAAGTGGATCGACGATGTGCTCGGAGAGCCGTTCGAGGCTGCCTGGCAGGCAACGCGCGGATACACTCAG
AAGGTCCATCCTGCCGAAGCCGCCCGCGCCGACAAAGACGGCAACAAACGCCTGGCCCTGGTTGCCCGCCGCTATCTGTT
CATGGGCGCTCAATGGGCCCGCGAAGGTCATCCGGGCCGCGCAGCCGACTACCAGATCTGGTGCGGCCCCGCGATGGGCG
CGTTCAATGAATGGGTCGCCGGCAGCTTCCTGGAGCCTGTCGAAGCCCGCACCGTTCGCCAGATCGCGCTGAACCTCATG
GAAGGCGCCGCGCGCGTCACACGGGCAGGCCAGCTGCGATCCATGGGTTTAACGGTGCCCGCCGACCTGTTCTCCTTCCG
GCCTGTCGCCTTCGAGTGA

Upstream 100 bases:

>100_bases
AACCTTAGTTTCAGGTTGAGTCGGTCTGCAAATGCCCTCTAAGACTATGCGCGGGGCGGACATTGATTCCGCTGCATTTC
GGCCAGAAGGGCGGGAAATT

Downstream 100 bases:

>100_bases
AATGATGACCCAGCACCGCAAGCCCGCCACCTTTGATCCTGCCGCGCCGATAGCGGTTGTCGGCATGGGCGCCATCTTCC
CCGGCCGCGGCGACACCACC

Product: 2-nitropropane dioxygenase family oxidoreductase

Products: NA

Alternate protein names: Malonyl CoA-acyl carrier protein transacylase; MCT [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MLDLIRKAVEAPRARAWISIPESGIPELVSVGAQPSGNASAAALPPVYPEWLGDRAFAAEHGARFNYVAGEMARGIATPK
MVIEAARAGCVGFYGSAGLPLAEIKSGVEEIKAALGPEARNWGANLIHSPQEPGQEKAVIDLFLSQAVSRVSASAFMRLT
ADVVRYTALGLTRAADGTIQRANHIFAKVSRAEVAEAFMAPAPEKILKDLVAEGAITAQQADLASKVPVAAEITAESDSG
GHTDNRPASTLFSSLAAARSRVAAHNGHPESSIRIGLAGGIATPQSVAAAFQMGAAYVLTGSINQSAIESGLAAPGRALL
AKAGPADVAMTPAADMFEQGVQVQVLKRGTLFAMRGKKFHAFYRSGASYETLPPTDQKWIDDVLGEPFEAAWQATRGYTQ
KVHPAEAARADKDGNKRLALVARRYLFMGAQWAREGHPGRAADYQIWCGPAMGAFNEWVAGSFLEPVEARTVRQIALNLM
EGAARVTRAGQLRSMGLTVPADLFSFRPVAFE

Sequences:

>Translated_512_residues
MLDLIRKAVEAPRARAWISIPESGIPELVSVGAQPSGNASAAALPPVYPEWLGDRAFAAEHGARFNYVAGEMARGIATPK
MVIEAARAGCVGFYGSAGLPLAEIKSGVEEIKAALGPEARNWGANLIHSPQEPGQEKAVIDLFLSQAVSRVSASAFMRLT
ADVVRYTALGLTRAADGTIQRANHIFAKVSRAEVAEAFMAPAPEKILKDLVAEGAITAQQADLASKVPVAAEITAESDSG
GHTDNRPASTLFSSLAAARSRVAAHNGHPESSIRIGLAGGIATPQSVAAAFQMGAAYVLTGSINQSAIESGLAAPGRALL
AKAGPADVAMTPAADMFEQGVQVQVLKRGTLFAMRGKKFHAFYRSGASYETLPPTDQKWIDDVLGEPFEAAWQATRGYTQ
KVHPAEAARADKDGNKRLALVARRYLFMGAQWAREGHPGRAADYQIWCGPAMGAFNEWVAGSFLEPVEARTVRQIALNLM
EGAARVTRAGQLRSMGLTVPADLFSFRPVAFE
>Mature_512_residues
MLDLIRKAVEAPRARAWISIPESGIPELVSVGAQPSGNASAAALPPVYPEWLGDRAFAAEHGARFNYVAGEMARGIATPK
MVIEAARAGCVGFYGSAGLPLAEIKSGVEEIKAALGPEARNWGANLIHSPQEPGQEKAVIDLFLSQAVSRVSASAFMRLT
ADVVRYTALGLTRAADGTIQRANHIFAKVSRAEVAEAFMAPAPEKILKDLVAEGAITAQQADLASKVPVAAEITAESDSG
GHTDNRPASTLFSSLAAARSRVAAHNGHPESSIRIGLAGGIATPQSVAAAFQMGAAYVLTGSINQSAIESGLAAPGRALL
AKAGPADVAMTPAADMFEQGVQVQVLKRGTLFAMRGKKFHAFYRSGASYETLPPTDQKWIDDVLGEPFEAAWQATRGYTQ
KVHPAEAARADKDGNKRLALVARRYLFMGAQWAREGHPGRAADYQIWCGPAMGAFNEWVAGSFLEPVEARTVRQIALNLM
EGAARVTRAGQLRSMGLTVPADLFSFRPVAFE

Specific function: Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably has an acyl transferase activity and could also have a flavin mononucleotide-dependent oxidoreductas

COG id: COG2070

COG function: function code R; Dioxygenases related to 2-nitropropane dioxygenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the fabD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004136
- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013785
- InterPro:   IPR004410
- InterPro:   IPR016036
- InterPro:   IPR014179 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF03060 NPD [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 54153; Mature: 54153

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLIRKAVEAPRARAWISIPESGIPELVSVGAQPSGNASAAALPPVYPEWLGDRAFAAE
CHHHHHHHHHCCCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCHHHHH
HGARFNYVAGEMARGIATPKMVIEAARAGCVGFYGSAGLPLAEIKSGVEEIKAALGPEAR
CCCCEEHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
NWGANLIHSPQEPGQEKAVIDLFLSQAVSRVSASAFMRLTADVVRYTALGLTRAADGTIQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RANHIFAKVSRAEVAEAFMAPAPEKILKDLVAEGAITAQQADLASKVPVAAEITAESDSG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCC
GHTDNRPASTLFSSLAAARSRVAAHNGHPESSIRIGLAGGIATPQSVAAAFQMGAAYVLT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEE
GSINQSAIESGLAAPGRALLAKAGPADVAMTPAADMFEQGVQVQVLKRGTLFAMRGKKFH
CCCCHHHHHHCCCCCCHHHHCCCCCCCEEECCCHHHHHCCCEEEEECCCCEEEECCCHHH
AFYRSGASYETLPPTDQKWIDDVLGEPFEAAWQATRGYTQKVHPAEAARADKDGNKRLAL
HHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHH
VARRYLFMGAQWAREGHPGRAADYQIWCGPAMGAFNEWVAGSFLEPVEARTVRQIALNLM
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EGAARVTRAGQLRSMGLTVPADLFSFRPVAFE
HHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MLDLIRKAVEAPRARAWISIPESGIPELVSVGAQPSGNASAAALPPVYPEWLGDRAFAAE
CHHHHHHHHHCCCCCEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCHHHHH
HGARFNYVAGEMARGIATPKMVIEAARAGCVGFYGSAGLPLAEIKSGVEEIKAALGPEAR
CCCCEEHHHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
NWGANLIHSPQEPGQEKAVIDLFLSQAVSRVSASAFMRLTADVVRYTALGLTRAADGTIQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
RANHIFAKVSRAEVAEAFMAPAPEKILKDLVAEGAITAQQADLASKVPVAAEITAESDSG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCC
GHTDNRPASTLFSSLAAARSRVAAHNGHPESSIRIGLAGGIATPQSVAAAFQMGAAYVLT
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEE
GSINQSAIESGLAAPGRALLAKAGPADVAMTPAADMFEQGVQVQVLKRGTLFAMRGKKFH
CCCCHHHHHHCCCCCCHHHHCCCCCCCEEECCCHHHHHCCCEEEEECCCCEEEECCCHHH
AFYRSGASYETLPPTDQKWIDDVLGEPFEAAWQATRGYTQKVHPAEAARADKDGNKRLAL
HHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHH
VARRYLFMGAQWAREGHPGRAADYQIWCGPAMGAFNEWVAGSFLEPVEARTVRQIALNLM
HHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EGAARVTRAGQLRSMGLTVPADLFSFRPVAFE
HHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]