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The map label for this gene is sigW [H]

Identifier: 114797400

GI number: 114797400

Start: 1352385

End: 1352930

Strand: Direct

Name: sigW [H]

Synonym: HNE_1318

Alternate gene names: 114797400

Gene position: 1352385-1352930 (Clockwise)

Preceding gene: 114798175

Following gene: 114797919

Centisome position: 36.5

GC content: 63.74

Gene sequence:

>546_bases
GTGGCGTTTACATCGGACCTTGACCAGATCACACGCGCCGCGGCGGGAGACGCCGCGGCCGTTCGGGCTATCGTCAACCG
GTACAGCCCCGGCGTGCTTTCACTTGCAACGCGCATGTTGGGCGACAGGGCAGAGGCAGAAGACGTGACCCAGGAAACAT
TCATCCGCGCCTGGAAGGCTCTGGCGACCTGGGAGCCGCGTGCGAAATTTTCCACATGGCTGCACCGTGTGGCGCTGAAC
CTCTGCTACGACCGGCTGCGAAAGCGCCGCGAAGTGCTTTCAGATGAAATTCCCGAACGCGCCGATACGGCCCTCGGGCC
GCAGGATGCGCTGGACCAGGCACAACGGGTGAACGCGGTGGAAGCCGCCATCAGCGCCCTGCCGGAACGCCAGTCTGCCG
CCTTGACCTTGTGCGCCCTGCAGGGACACTCACAGACAGAAGCGGCGGAAATCATGGATGTCAGCGTTGAAGCCCTGGAA
AGTCTGCTCGCCCGCGCGCGGCGCACATTGCGCGGACAACTGCTCGATGGAAGGAATGCCTCATGA

Upstream 100 bases:

>100_bases
GGCCCGAATTGGGAACGGGCCGGAACCATTTTGAGACGATTGATCCCCCCCTGCGATTGTCTCTCGGTATTCCGGCCCGG
ACTCAGCTAAACATCCCCTC

Downstream 100 bases:

>100_bases
CCTGTCCCATGACTGATGATCGCCTGATCGAGCTGATCGAGACCTGGGGCGCGGAAGCCGCCTGCTGGCCCGAAGCGGAG
CGTGATGCGGGCAAGGCGCT

Product: ECF subfamily RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAFTSDLDQITRAAAGDAAAVRAIVNRYSPGVLSLATRMLGDRAEAEDVTQETFIRAWKALATWEPRAKFSTWLHRVALN
LCYDRLRKRREVLSDEIPERADTALGPQDALDQAQRVNAVEAAISALPERQSAALTLCALQGHSQTEAAEIMDVSVEALE
SLLARARRTLRGQLLDGRNAS

Sequences:

>Translated_181_residues
MAFTSDLDQITRAAAGDAAAVRAIVNRYSPGVLSLATRMLGDRAEAEDVTQETFIRAWKALATWEPRAKFSTWLHRVALN
LCYDRLRKRREVLSDEIPERADTALGPQDALDQAQRVNAVEAAISALPERQSAALTLCALQGHSQTEAAEIMDVSVEALE
SLLARARRTLRGQLLDGRNAS
>Mature_180_residues
AFTSDLDQITRAAAGDAAAVRAIVNRYSPGVLSLATRMLGDRAEAEDVTQETFIRAWKALATWEPRAKFSTWLHRVALNL
CYDRLRKRREVLSDEIPERADTALGPQDALDQAQRVNAVEAAISALPERQSAALTLCALQGHSQTEAAEIMDVSVEALES
LLARARRTLRGQLLDGRNAS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=176, Percent_Identity=32.3863636363636, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 19857; Mature: 19725

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFTSDLDQITRAAAGDAAAVRAIVNRYSPGVLSLATRMLGDRAEAEDVTQETFIRAWKA
CCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LATWEPRAKFSTWLHRVALNLCYDRLRKRREVLSDEIPERADTALGPQDALDQAQRVNAV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHH
EAAISALPERQSAALTLCALQGHSQTEAAEIMDVSVEALESLLARARRTLRGQLLDGRNA
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
S
C
>Mature Secondary Structure 
AFTSDLDQITRAAAGDAAAVRAIVNRYSPGVLSLATRMLGDRAEAEDVTQETFIRAWKA
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LATWEPRAKFSTWLHRVALNLCYDRLRKRREVLSDEIPERADTALGPQDALDQAQRVNAV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHH
EAAISALPERQSAALTLCALQGHSQTEAAEIMDVSVEALESLLARARRTLRGQLLDGRNA
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]