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The map label for this gene is mdtA [H]

Identifier: 114797281

GI number: 114797281

Start: 197808

End: 198953

Strand: Reverse

Name: mdtA [H]

Synonym: HNE_0212

Alternate gene names: 114797281

Gene position: 198953-197808 (Counterclockwise)

Preceding gene: 114799824

Following gene: 114797729

Centisome position: 5.37

GC content: 65.53

Gene sequence:

>1146_bases
ATGCTGACGCTTAGCCGACCTAACATATTCAAAGCCGCCGGCGTGGCGCTTGTGGCCGCAATCCTGATTGCGGCCCCTGC
CCTGACCCAGCAGCGTGGCGGCGGCCCGGCCGGCGCCGGTCGCGCGCCCCCGCCCAGCAGCGTTTTTGCCGAACCTATCC
GCGAACAGGTCTTCGCCAGCCGTGTCGAAGCAATCGGCACACTGGAACCCAATGAGATGGCAGCCCTGACCCTGACCGCG
TCAGACCGCGTCACGGCCGTTTATTTCAATGACGGGGACCGCGTGAAGAAGGGCAAGACCCTCCTGTCTCTGGCCCAGCG
CGAGCAGGTTGCCCTTGTCGAGTCCGCCGAAGCTGACCTTGCCCAGGCCGAGCAGGATCTGGCCCGCGTCGAACCGCTGG
CAAAGCAAGGCGCCGTCTCGACATCTGAACTCGACATGGCCCGCCGGAATGTCAACGCTGCTGCGGCCCAGCTGCGCGCC
GTTCAGTCGCGCCAGCGCGACCGCGTTCTGGTTGCCCCGTTCGACGGCGTTCTCGGCTTTCGCCGTGTCAGCGTCGGTTC
GCTCGTCGGCCCCGGCGATGTCGTCGCCACCCTGATCGATGACAGCGTCATGCGCCTTGAATTTGCCGTGCCGTCCACTT
TCCTGCGCGTGCTTCGCCCCGGCCTCGAAATTCAGGCATCCAGCGACGACCTGCCCGGCCAGGTTTTCAACGGCACTGTG
GATTCCATCGACAACGCCATCGACCCCATCACCCGCTCCGTCCGTGTGCGCGCAAATGTTCCGAACCCGTCGGCGATCCT
CAAGGCCGGCATGTATATGTCGGTCACTCTGGAAGCGGCCCCGCGCCGGGCGATGTCTGTCCCCGAAGTCGCGCTGCAGC
CGCGTGGCCCAGAAACCTTTGTCTGGATTGCAGAGAAAGACGGCGCGCAAACCGTTGCCCGCCGCGTGAAGATCGAACCC
GGCCTGCGCCATGAAGGCCGGGTTGAAGTGGTTTCCGGGCTCACTGCCGGCCAGATGGTAATCACGGAAGGCGCCCTGCG
CGTCCGCGAAGGCGCCCCCGTCGTGATCGTGGATGAAGGCATTCTCCAGCCCCAACCCGCCGCGCGAAGTGGTTCTGTGG
GTGGCCCAGCCGTGAACCTGGATTGA

Upstream 100 bases:

>100_bases
GGCAGAAACCGCCCGGCGCGCCGTCCGCGCTTACAGAAGCCTGGGCGGTATCTGGACCGACGAAGAACTCGCCGCCTACC
GGGCGGGATAGGAAAATCCG

Downstream 100 bases:

>100_bases
GCCGATGTTTCTGTCGGACACATCGGTAAAACGCCCGGTATTCGCTTCGGTCCTGTCGATTTTGCTGATCGTGTTCGGCC
TGGTGGCGTTTTCGCGCCTG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MLTLSRPNIFKAAGVALVAAILIAAPALTQQRGGGPAGAGRAPPPSSVFAEPIREQVFASRVEAIGTLEPNEMAALTLTA
SDRVTAVYFNDGDRVKKGKTLLSLAQREQVALVESAEADLAQAEQDLARVEPLAKQGAVSTSELDMARRNVNAAAAQLRA
VQSRQRDRVLVAPFDGVLGFRRVSVGSLVGPGDVVATLIDDSVMRLEFAVPSTFLRVLRPGLEIQASSDDLPGQVFNGTV
DSIDNAIDPITRSVRVRANVPNPSAILKAGMYMSVTLEAAPRRAMSVPEVALQPRGPETFVWIAEKDGAQTVARRVKIEP
GLRHEGRVEVVSGLTAGQMVITEGALRVREGAPVVIVDEGILQPQPAARSGSVGGPAVNLD

Sequences:

>Translated_381_residues
MLTLSRPNIFKAAGVALVAAILIAAPALTQQRGGGPAGAGRAPPPSSVFAEPIREQVFASRVEAIGTLEPNEMAALTLTA
SDRVTAVYFNDGDRVKKGKTLLSLAQREQVALVESAEADLAQAEQDLARVEPLAKQGAVSTSELDMARRNVNAAAAQLRA
VQSRQRDRVLVAPFDGVLGFRRVSVGSLVGPGDVVATLIDDSVMRLEFAVPSTFLRVLRPGLEIQASSDDLPGQVFNGTV
DSIDNAIDPITRSVRVRANVPNPSAILKAGMYMSVTLEAAPRRAMSVPEVALQPRGPETFVWIAEKDGAQTVARRVKIEP
GLRHEGRVEVVSGLTAGQMVITEGALRVREGAPVVIVDEGILQPQPAARSGSVGGPAVNLD
>Mature_381_residues
MLTLSRPNIFKAAGVALVAAILIAAPALTQQRGGGPAGAGRAPPPSSVFAEPIREQVFASRVEAIGTLEPNEMAALTLTA
SDRVTAVYFNDGDRVKKGKTLLSLAQREQVALVESAEADLAQAEQDLARVEPLAKQGAVSTSELDMARRNVNAAAAQLRA
VQSRQRDRVLVAPFDGVLGFRRVSVGSLVGPGDVVATLIDDSVMRLEFAVPSTFLRVLRPGLEIQASSDDLPGQVFNGTV
DSIDNAIDPITRSVRVRANVPNPSAILKAGMYMSVTLEAAPRRAMSVPEVALQPRGPETFVWIAEKDGAQTVARRVKIEP
GLRHEGRVEVVSGLTAGQMVITEGALRVREGAPVVIVDEGILQPQPAARSGSVGGPAVNLD

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=370, Percent_Identity=29.4594594594595, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789929, Length=295, Percent_Identity=27.4576271186441, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40131; Mature: 40131

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLSRPNIFKAAGVALVAAILIAAPALTQQRGGGPAGAGRAPPPSSVFAEPIREQVFAS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVEAIGTLEPNEMAALTLTASDRVTAVYFNDGDRVKKGKTLLSLAQREQVALVESAEADL
HHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AQAEQDLARVEPLAKQGAVSTSELDMARRNVNAAAAQLRAVQSRQRDRVLVAPFDGVLGF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHH
RRVSVGSLVGPGDVVATLIDDSVMRLEFAVPSTFLRVLRPGLEIQASSDDLPGQVFNGTV
HHCCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEECCCCCCCHHHCCCH
DSIDNAIDPITRSVRVRANVPNPSAILKAGMYMSVTLEAAPRRAMSVPEVALQPRGPETF
HHHHHHHHHHHHCEEEEECCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCEECCCCCCEE
VWIAEKDGAQTVARRVKIEPGLRHEGRVEVVSGLTAGQMVITEGALRVREGAPVVIVDEG
EEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEECCCEEEECCCCEEEECCC
ILQPQPAARSGSVGGPAVNLD
CCCCCCCCCCCCCCCCEECCC
>Mature Secondary Structure
MLTLSRPNIFKAAGVALVAAILIAAPALTQQRGGGPAGAGRAPPPSSVFAEPIREQVFAS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVEAIGTLEPNEMAALTLTASDRVTAVYFNDGDRVKKGKTLLSLAQREQVALVESAEADL
HHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AQAEQDLARVEPLAKQGAVSTSELDMARRNVNAAAAQLRAVQSRQRDRVLVAPFDGVLGF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHH
RRVSVGSLVGPGDVVATLIDDSVMRLEFAVPSTFLRVLRPGLEIQASSDDLPGQVFNGTV
HHCCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCEEEECCCCCCCHHHCCCH
DSIDNAIDPITRSVRVRANVPNPSAILKAGMYMSVTLEAAPRRAMSVPEVALQPRGPETF
HHHHHHHHHHHHCEEEEECCCCHHHHHHCCCEEEEEEECCCCCCCCCCCCEECCCCCCEE
VWIAEKDGAQTVARRVKIEPGLRHEGRVEVVSGLTAGQMVITEGALRVREGAPVVIVDEG
EEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEECCCEEEECCCCEEEECCC
ILQPQPAARSGSVGGPAVNLD
CCCCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA