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The map label for this gene is ilvE [H]

Identifier: 114797240

GI number: 114797240

Start: 2642924

End: 2643889

Strand: Direct

Name: ilvE [H]

Synonym: HNE_2507

Alternate gene names: 114797240

Gene position: 2642924-2643889 (Clockwise)

Preceding gene: 114798942

Following gene: 114799150

Centisome position: 71.33

GC content: 58.18

Gene sequence:

>966_bases
ATGCTGACATTTCAAAAAGTGCTGACCGGATTTCAGACGCGGGCAGACGCTCGCGCAGAGCGAACAGACGCGTTCGCCGA
CGGTATTGCCTGGATCGAAAACGAATTTGTGCCCATCGGAAAGGCGCGGATACCGATACTTGATCAGGGCTTCCTGCATT
CGGATCTGACCTATGACGTCCCCGCAGTCTGGAATGGCCGGATCTTCCGTCTCGATGATCACCTGGACCGTCTGGAAGTT
AGCTGCGCCAAAATGCGGCTCCCGCTGCCGATCGCCAGGCCAGAGCTCCGCAGGCTGGTGATGGAGCTGGTCTCCAGGAG
TGGGCTGCGGGACGCATATGTTGAGATCATCGTGACCCGCGGGTTGAAGTTCCTGCGAGGCGCACAAGCCGAAGACATCA
TCCCGAACCTGTATCTCATGGCGGTGCCTTACGTCTGGATTCTCCCGCTTGAATACCAGAACCATGGCGCGCCGGCCGTC
GTAACGCGAACGGTGCGCCGCACACCCCCGGGGGCCCTGGACCCGACAATCAAGAACCTTCAGTGGGGCGATCTCGTCCG
AGGGCTTATGGAAGCAGGTGACCGGGACTCTTTCTTCCCCATTCTTCCCGACGGCGACGGGAACGCCACAGAAGGCGCTG
GCTATAATATCGTCCTTGTCAGGAATGGGGAACTTCACACACCCCGTCGCGGGGTGCTGGAAGGCATCACACGCAGGACA
GTACTGGAAATAGCGGCCGCGCGCGGCCTGAAAACACATGTTACCGAGATACCCATCCAGGCACTCTATGAATGCGATGA
ATTGTTCATGTGTTCGACGGCAGGCGGCATAATGCCACTCGTCCTTCTGGATGGGAACATTGTGGGTGATGGAACAGTCG
GTCCGGTTACACGGATGATTTGGGAGGCTTACTGGGATCTTCATGATGATCCTCAGCTCAGCGAGCCTGTGACTTACGCG
CCCTGA

Upstream 100 bases:

>100_bases
ACGGGATCAAATCTACGAGCTTTTAGTCAATATTTATTGACTTTCTGGGCGCAGCAGTTTCGGATGATGTCGTGAAATGC
AAAAACGACAGGGGACCGCA

Downstream 100 bases:

>100_bases
GCGCAGCGCCAGCCGCGCCGGGCGCAGCTCCCCCTGCCCCCCCTACTCCGGATATCCAGATCAGCTGCTCGGATCTTCGC
CGCGCGCATCCGTCATCTGG

Product: class IV aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MLTFQKVLTGFQTRADARAERTDAFADGIAWIENEFVPIGKARIPILDQGFLHSDLTYDVPAVWNGRIFRLDDHLDRLEV
SCAKMRLPLPIARPELRRLVMELVSRSGLRDAYVEIIVTRGLKFLRGAQAEDIIPNLYLMAVPYVWILPLEYQNHGAPAV
VTRTVRRTPPGALDPTIKNLQWGDLVRGLMEAGDRDSFFPILPDGDGNATEGAGYNIVLVRNGELHTPRRGVLEGITRRT
VLEIAAARGLKTHVTEIPIQALYECDELFMCSTAGGIMPLVLLDGNIVGDGTVGPVTRMIWEAYWDLHDDPQLSEPVTYA
P

Sequences:

>Translated_321_residues
MLTFQKVLTGFQTRADARAERTDAFADGIAWIENEFVPIGKARIPILDQGFLHSDLTYDVPAVWNGRIFRLDDHLDRLEV
SCAKMRLPLPIARPELRRLVMELVSRSGLRDAYVEIIVTRGLKFLRGAQAEDIIPNLYLMAVPYVWILPLEYQNHGAPAV
VTRTVRRTPPGALDPTIKNLQWGDLVRGLMEAGDRDSFFPILPDGDGNATEGAGYNIVLVRNGELHTPRRGVLEGITRRT
VLEIAAARGLKTHVTEIPIQALYECDELFMCSTAGGIMPLVLLDGNIVGDGTVGPVTRMIWEAYWDLHDDPQLSEPVTYA
P
>Mature_321_residues
MLTFQKVLTGFQTRADARAERTDAFADGIAWIENEFVPIGKARIPILDQGFLHSDLTYDVPAVWNGRIFRLDDHLDRLEV
SCAKMRLPLPIARPELRRLVMELVSRSGLRDAYVEIIVTRGLKFLRGAQAEDIIPNLYLMAVPYVWILPLEYQNHGAPAV
VTRTVRRTPPGALDPTIKNLQWGDLVRGLMEAGDRDSFFPILPDGDGNATEGAGYNIVLVRNGELHTPRRGVLEGITRRT
VLEIAAARGLKTHVTEIPIQALYECDELFMCSTAGGIMPLVLLDGNIVGDGTVGPVTRMIWEAYWDLHDDPQLSEPVTYA
P

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=285, Percent_Identity=25.9649122807018, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 35779; Mature: 35779

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFQKVLTGFQTRADARAERTDAFADGIAWIENEFVPIGKARIPILDQGFLHSDLTYDV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEECCCCCCCCCCCCC
PAVWNGRIFRLDDHLDRLEVSCAKMRLPLPIARPELRRLVMELVSRSGLRDAYVEIIVTR
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
GLKFLRGAQAEDIIPNLYLMAVPYVWILPLEYQNHGAPAVVTRTVRRTPPGALDPTIKNL
HHHHHHCCCHHHHCCHHHHHHCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHCC
QWGDLVRGLMEAGDRDSFFPILPDGDGNATEGAGYNIVLVRNGELHTPRRGVLEGITRRT
CHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
VLEIAAARGLKTHVTEIPIQALYECDELFMCSTAGGIMPLVLLDGNIVGDGTVGPVTRMI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCEEECCCCHHHHHHHH
WEAYWDLHDDPQLSEPVTYAP
HHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTFQKVLTGFQTRADARAERTDAFADGIAWIENEFVPIGKARIPILDQGFLHSDLTYDV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEECCCCCCCCCCCCC
PAVWNGRIFRLDDHLDRLEVSCAKMRLPLPIARPELRRLVMELVSRSGLRDAYVEIIVTR
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
GLKFLRGAQAEDIIPNLYLMAVPYVWILPLEYQNHGAPAVVTRTVRRTPPGALDPTIKNL
HHHHHHCCCHHHHCCHHHHHHCCEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCHHHCC
QWGDLVRGLMEAGDRDSFFPILPDGDGNATEGAGYNIVLVRNGELHTPRRGVLEGITRRT
CHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHH
VLEIAAARGLKTHVTEIPIQALYECDELFMCSTAGGIMPLVLLDGNIVGDGTVGPVTRMI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEEECCEEECCCCHHHHHHHH
WEAYWDLHDDPQLSEPVTYAP
HHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]