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The map label for this gene is cinA [C]

Identifier: 114797094

GI number: 114797094

Start: 970242

End: 971000

Strand: Direct

Name: cinA [C]

Synonym: HNE_0955

Alternate gene names: 114797094

Gene position: 970242-971000 (Clockwise)

Preceding gene: 114797477

Following gene: 114799848

Centisome position: 26.19

GC content: 65.35

Gene sequence:

>759_bases
ATGACCCAGCCCACCGCCGCCGTCCTGCTGATCGGAGATGAACTCCTCTCAGGGCGCACCCGCGACATCAATCTCCAGCA
GATCGCCCAATATCTGGAGCCGATCGGCATTCCCGTGCGCGAGTGCCGGACGGTTTCGGATGTGCAGGAGGAAATCGTCG
CGGCGGTGAACGCCCTGCGGGCAAAATACACCTACGTCTTCACCACCGGCGGCATCGGCCCGACGCATGACGACATCACG
GCGGATGCGATTGCGGCGGCGTTCAACACCGGTATTTCCGAACATCCCGAGGTGATCGCCGACATGGCCAAACGCTATGA
GGCCATGAACACCGAATTCACCCCCGCCCGCCGCCGCATGGCGCGCATCCCGCATGGCGCAAAGATCGTGCAGAACCCCG
TTTCGGGCGCGCCGGGCTTCCAGATGGAGAACGTGTTCACGCTGGCGGGCGTGCCCCAGATCGCTCGCGCGATGCTGGAA
GACATCGGCCCGCGCCTTGAAGGCGGGGAGCGGGTTCACAAGGTTCAGCTGCGCGGAACCGGTCTGCGCGAAGGCGACAT
TGCCGAGCGGCTTGGCGCGATTGCCAAGACGTATCCCAGCGTCTCCATCGGCTCCTATCCCTGGTATCTGGGCATGGGCG
ACAATGGCGTCGCGCTGGTCGCCCGCGCCACCGATACCGGCCTCCTCGCCACCGTGCAGGGCGAGCTTGAAGCGCTGATG
CGCAGCCTGGGTGTGGAGCCTGTGCTGGATCCCGCCTGA

Upstream 100 bases:

>100_bases
ACTTCATCGGCATGGTGCAGCATTTCGGCGGGGCAGGCCCCGGTTTTGATGCCCGCGCCGAGTCTGCCCGTCTCGTCTAT
GAAGCCCTTGAGGATCCTGA

Downstream 100 bases:

>100_bases
CGCAAAAAAGCGTGGATAAGGGGGTGAAAAAAACTCAAACCATTCCTCCAACCACGCGCTATAAAACTCCAACAAAACTC
CTGGGGGGAGACAAACACAT

Product: molybdopterin-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MTQPTAAVLLIGDELLSGRTRDINLQQIAQYLEPIGIPVRECRTVSDVQEEIVAAVNALRAKYTYVFTTGGIGPTHDDIT
ADAIAAAFNTGISEHPEVIADMAKRYEAMNTEFTPARRRMARIPHGAKIVQNPVSGAPGFQMENVFTLAGVPQIARAMLE
DIGPRLEGGERVHKVQLRGTGLREGDIAERLGAIAKTYPSVSIGSYPWYLGMGDNGVALVARATDTGLLATVQGELEALM
RSLGVEPVLDPA

Sequences:

>Translated_252_residues
MTQPTAAVLLIGDELLSGRTRDINLQQIAQYLEPIGIPVRECRTVSDVQEEIVAAVNALRAKYTYVFTTGGIGPTHDDIT
ADAIAAAFNTGISEHPEVIADMAKRYEAMNTEFTPARRRMARIPHGAKIVQNPVSGAPGFQMENVFTLAGVPQIARAMLE
DIGPRLEGGERVHKVQLRGTGLREGDIAERLGAIAKTYPSVSIGSYPWYLGMGDNGVALVARATDTGLLATVQGELEALM
RSLGVEPVLDPA
>Mature_251_residues
TQPTAAVLLIGDELLSGRTRDINLQQIAQYLEPIGIPVRECRTVSDVQEEIVAAVNALRAKYTYVFTTGGIGPTHDDITA
DAIAAAFNTGISEHPEVIADMAKRYEAMNTEFTPARRRMARIPHGAKIVQNPVSGAPGFQMENVFTLAGVPQIARAMLED
IGPRLEGGERVHKVQLRGTGLREGDIAERLGAIAKTYPSVSIGSYPWYLGMGDNGVALVARATDTGLLATVQGELEALMR
SLGVEPVLDPA

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family [H]

Homologues:

Organism=Homo sapiens, GI41872389, Length=164, Percent_Identity=31.7073170731707, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI41872403, Length=162, Percent_Identity=32.0987654320988, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI296434309, Length=162, Percent_Identity=32.0987654320988, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI296434312, Length=149, Percent_Identity=30.8724832214765, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1788583, Length=208, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71993974, Length=226, Percent_Identity=29.646017699115, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71993966, Length=226, Percent_Identity=29.646017699115, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323832, Length=249, Percent_Identity=30.5220883534137, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453 [H]

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 27020; Mature: 26889

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQPTAAVLLIGDELLSGRTRDINLQQIAQYLEPIGIPVRECRTVSDVQEEIVAAVNALR
CCCCCEEEEEECHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AKYTYVFTTGGIGPTHDDITADAIAAAFNTGISEHPEVIADMAKRYEAMNTEFTPARRRM
HEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
ARIPHGAKIVQNPVSGAPGFQMENVFTLAGVPQIARAMLEDIGPRLEGGERVHKVQLRGT
HHCCCCHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
GLREGDIAERLGAIAKTYPSVSIGSYPWYLGMGDNGVALVARATDTGLLATVQGELEALM
CCCCCHHHHHHHHHHHHCCCCEECCCCEEEEECCCCEEEEEEECCCCEEEEHHHHHHHHH
RSLGVEPVLDPA
HHCCCCCCCCCC
>Mature Secondary Structure 
TQPTAAVLLIGDELLSGRTRDINLQQIAQYLEPIGIPVRECRTVSDVQEEIVAAVNALR
CCCCEEEEEECHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AKYTYVFTTGGIGPTHDDITADAIAAAFNTGISEHPEVIADMAKRYEAMNTEFTPARRRM
HEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
ARIPHGAKIVQNPVSGAPGFQMENVFTLAGVPQIARAMLEDIGPRLEGGERVHKVQLRGT
HHCCCCHHHHCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCEEEEEEECCC
GLREGDIAERLGAIAKTYPSVSIGSYPWYLGMGDNGVALVARATDTGLLATVQGELEALM
CCCCCHHHHHHHHHHHHCCCCEECCCCEEEEECCCCEEEEEEECCCCEEEEHHHHHHHHH
RSLGVEPVLDPA
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA