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The map label for this gene is blh [H]

Identifier: 114332477

GI number: 114332477

Start: 2657425

End: 2658288

Strand: Direct

Name: blh [H]

Synonym: Neut_2530

Alternate gene names: 114332477

Gene position: 2657425-2658288 (Clockwise)

Preceding gene: 114332468

Following gene: NA

Centisome position: 99.86

GC content: 49.54

Gene sequence:

>864_bases
ATGCAACCCAATATCCAAGCTTTCTTTGATCCTGTTACCGGGACAGTCAGCTATGTTGTGTTTGACAGGTCGGGAGGGCG
TTGCGCCATTATCGACCCGGTGCTTGATTACGATCCCAAATCCGGGAGAACAAAACACCACTCCGCTGATGTACTGATCA
AATTTGTGCACTCAAAGAAGTTGACGACGGATTGGATACTTGAAACCCATGCGCACGCTGATCATCTTTCTTCAGCGCAC
TACCTCAAGCAGGAACTAGGGGGGAAAACAGCCATAGGCAGCCGGATTCCCGACGTGCAGCAGGTATTTAAAAAGCTGTT
CAACATGGGGGCAGATTTTCAGCCGGATGGCTCGCAATTTGATCATCTGTTTGATGACGGTGACAGCTTTGAGGTGGGCG
AACTCAAGGGTAAGGTGATTTTCGTACCTGGCCACACACCGGCTGACCTTGCTTATCAGTTCGACGATGCAATTTTTATC
AGTGATACGATGTTTATGCCAGATATAGGGACGGCACGTGCCGATTTCCCCGGAGGCGATGCCCGGCAGCTTTATCGATC
TATCCGCAGGTTGCTGAATAATTATCCACCGGAAACAAGATTGTTCATGTGCCATGACTATCCACCCGGTGACCGCCCGG
TACAGTGGGAAAGCACAGTCGCTGACCAGTGTGCCAACAATATTCATGTACACGACGGTATCAGTGAAGACGAATTTGTC
GCGATACGTACCACACGTGATGCCACATTAGATGTGCCGGTACTGATTCTGCCATCCGTTCAGGTCAATGTGCGTGCCGG
CCAGATGCCACCCGCTGAAGATAATGGCACTGTGTATTTGAAAATACCGATTAATGTATTGTAA

Upstream 100 bases:

>100_bases
CTCCTTGACAGATAAATTATCCTAACACATTATATATTTTTATGATTTAATGTTTTATATATTAAAAATATTTGAATACA
AACAACCCAAGGAGATGATG

Downstream 100 bases:

>100_bases
GCAGGTTTATGTGAACACCTGGTCAGGAAACTGGCCGGGAAGAATGTACCTACAGGAGTTTTTGATCAATCAGAAGTTTT
CTAGTTACCAATAGCGAACG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MQPNIQAFFDPVTGTVSYVVFDRSGGRCAIIDPVLDYDPKSGRTKHHSADVLIKFVHSKKLTTDWILETHAHADHLSSAH
YLKQELGGKTAIGSRIPDVQQVFKKLFNMGADFQPDGSQFDHLFDDGDSFEVGELKGKVIFVPGHTPADLAYQFDDAIFI
SDTMFMPDIGTARADFPGGDARQLYRSIRRLLNNYPPETRLFMCHDYPPGDRPVQWESTVADQCANNIHVHDGISEDEFV
AIRTTRDATLDVPVLILPSVQVNVRAGQMPPAEDNGTVYLKIPINVL

Sequences:

>Translated_287_residues
MQPNIQAFFDPVTGTVSYVVFDRSGGRCAIIDPVLDYDPKSGRTKHHSADVLIKFVHSKKLTTDWILETHAHADHLSSAH
YLKQELGGKTAIGSRIPDVQQVFKKLFNMGADFQPDGSQFDHLFDDGDSFEVGELKGKVIFVPGHTPADLAYQFDDAIFI
SDTMFMPDIGTARADFPGGDARQLYRSIRRLLNNYPPETRLFMCHDYPPGDRPVQWESTVADQCANNIHVHDGISEDEFV
AIRTTRDATLDVPVLILPSVQVNVRAGQMPPAEDNGTVYLKIPINVL
>Mature_287_residues
MQPNIQAFFDPVTGTVSYVVFDRSGGRCAIIDPVLDYDPKSGRTKHHSADVLIKFVHSKKLTTDWILETHAHADHLSSAH
YLKQELGGKTAIGSRIPDVQQVFKKLFNMGADFQPDGSQFDHLFDDGDSFEVGELKGKVIFVPGHTPADLAYQFDDAIFI
SDTMFMPDIGTARADFPGGDARQLYRSIRRLLNNYPPETRLFMCHDYPPGDRPVQWESTVADQCANNIHVHDGISEDEFV
AIRTTRDATLDVPVLILPSVQVNVRAGQMPPAEDNGTVYLKIPINVL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=269, Percent_Identity=27.5092936802974, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538952, Length=268, Percent_Identity=23.8805970149254, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221330176, Length=264, Percent_Identity=25, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 31981; Mature: 31981

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPNIQAFFDPVTGTVSYVVFDRSGGRCAIIDPVLDYDPKSGRTKHHSADVLIKFVHSKK
CCCCCCEEECCCCCEEEEEEEECCCCEEEEECHHHCCCCCCCCCCCCCHHHHEEEHHCCC
LTTDWILETHAHADHLSSAHYLKQELGGKTAIGSRIPDVQQVFKKLFNMGADFQPDGSQF
CCHHHHEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHH
DHLFDDGDSFEVGELKGKVIFVPGHTPADLAYQFDDAIFISDTMFMPDIGTARADFPGGD
HHHHCCCCCEEECCCCCEEEEECCCCCHHHEEECCCEEEEECEEECCCCCCCCCCCCCCH
ARQLYRSIRRLLNNYPPETRLFMCHDYPPGDRPVQWESTVADQCANNIHVHDGISEDEFV
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCEE
AIRTTRDATLDVPVLILPSVQVNVRAGQMPPAEDNGTVYLKIPINVL
EEEECCCCEECCCEEEECCEEEEEEECCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure
MQPNIQAFFDPVTGTVSYVVFDRSGGRCAIIDPVLDYDPKSGRTKHHSADVLIKFVHSKK
CCCCCCEEECCCCCEEEEEEEECCCCEEEEECHHHCCCCCCCCCCCCCHHHHEEEHHCCC
LTTDWILETHAHADHLSSAHYLKQELGGKTAIGSRIPDVQQVFKKLFNMGADFQPDGSQF
CCHHHHEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHH
DHLFDDGDSFEVGELKGKVIFVPGHTPADLAYQFDDAIFISDTMFMPDIGTARADFPGGD
HHHHCCCCCEEECCCCCEEEEECCCCCHHHEEECCCEEEEECEEECCCCCCCCCCCCCCH
ARQLYRSIRRLLNNYPPETRLFMCHDYPPGDRPVQWESTVADQCANNIHVHDGISEDEFV
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCEE
AIRTTRDATLDVPVLILPSVQVNVRAGQMPPAEDNGTVYLKIPINVL
EEEECCCCEECCCEEEECCEEEEEEECCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]