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The map label for this gene is thiL [H]

Identifier: 114332466

GI number: 114332466

Start: 2647229

End: 2648215

Strand: Direct

Name: thiL [H]

Synonym: Neut_2519

Alternate gene names: 114332466

Gene position: 2647229-2648215 (Clockwise)

Preceding gene: 114332465

Following gene: 114332467

Centisome position: 99.48

GC content: 50.05

Gene sequence:

>987_bases
ATGAACTCCGAGTTTGACATCATTAATCGCTATTTTTCCCGTCCCGTACGCAACGCGCTGCTGGGGCCGGGAGATGATGC
CGCATTAATTACCTGCACACCAGGAATGGATTGGGCCGTATCGGTTGATACGCTGGTCTCGGGACGACATTTTTTCCTCG
ATATTGAGCCTTCTACACTGGGTCACAAAGTGCTTGCTGTCAATCTTTCCGATATGGCTGCCATGGGTGCTACACCGCGC
TGGATAACGCTTTCTCTGACATTAACTGAAACACTCGCACAGGATGATGCCTGGCTCAAGGCTTTTTCCAGTGGGTTTTT
CGCGCTGGCAGATCAGTATCAGATCGAGTTAATCGGCGGAGATACCACCAGCGGCCCACTCAATATTGGTGTACAGATCA
TTGGCGAAGTCGAGCAGGGCAAAGCCCTCCGGCGAAGTGACGCCAAGCCGGGAGATGATATCTGGGTATCCGGTTTTTTG
GGAGACGCTGCCCTGGCGCTGCAATTCCTGCAACAGCGTATAACACTGACGGAGCAAGAGGCAACTCCTTGTCTAATCGC
ATTGTATACCCCCACACCGCGTGTTGTTCTTGGAAAAGCGCTGGTAAATGTAGCGCATAGTGCAATTGATATTTCCGATG
GTCTGCTGGCTGATCTCGGCCATATTCTGGAACGATCCGATGTTGCCGCCACAGTTGATTTCGACCGCATTCCCTGCTCT
CCGGCATTAAAAAACAAACTGCAACAGGAAAATGCCACTCGGCAATTGGCCATTGACTGTTTATTATCAGGCGGTGATGA
TTATGAACTGTGTTTCACCGCACCAGAAAACAGGCATGATGTCATTGCACAACTTGCGCAGCAAACGGGCGTGAAACTCT
CCCGCATCGGCAAAATCGTGCCGGGAAAAGGATTGGCCGTACTAAATGCCAATGATAACCCGCTAATTTTTAATAATAAA
GGCTATGATCACTTCCTTACCCGATGA

Upstream 100 bases:

>100_bases
GCTGGGGGGTTGCTTCCCGCCATCCGTCAACATCACACTCACGGTTGCAGTCCGCAATAATAGCTATCGATTTATCTAAC
TTTTCATAAATGGTGTAGCT

Downstream 100 bases:

>100_bases
CTATTCACCACGACGTCAAACGCCACTAAAACCAGATATTACCTTTGTGCATGTCCGGCTAGCGCATTTCATTGCAATGG
GCGCTGGTGTCGGTCTCATC

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MNSEFDIINRYFSRPVRNALLGPGDDAALITCTPGMDWAVSVDTLVSGRHFFLDIEPSTLGHKVLAVNLSDMAAMGATPR
WITLSLTLTETLAQDDAWLKAFSSGFFALADQYQIELIGGDTTSGPLNIGVQIIGEVEQGKALRRSDAKPGDDIWVSGFL
GDAALALQFLQQRITLTEQEATPCLIALYTPTPRVVLGKALVNVAHSAIDISDGLLADLGHILERSDVAATVDFDRIPCS
PALKNKLQQENATRQLAIDCLLSGGDDYELCFTAPENRHDVIAQLAQQTGVKLSRIGKIVPGKGLAVLNANDNPLIFNNK
GYDHFLTR

Sequences:

>Translated_328_residues
MNSEFDIINRYFSRPVRNALLGPGDDAALITCTPGMDWAVSVDTLVSGRHFFLDIEPSTLGHKVLAVNLSDMAAMGATPR
WITLSLTLTETLAQDDAWLKAFSSGFFALADQYQIELIGGDTTSGPLNIGVQIIGEVEQGKALRRSDAKPGDDIWVSGFL
GDAALALQFLQQRITLTEQEATPCLIALYTPTPRVVLGKALVNVAHSAIDISDGLLADLGHILERSDVAATVDFDRIPCS
PALKNKLQQENATRQLAIDCLLSGGDDYELCFTAPENRHDVIAQLAQQTGVKLSRIGKIVPGKGLAVLNANDNPLIFNNK
GYDHFLTR
>Mature_328_residues
MNSEFDIINRYFSRPVRNALLGPGDDAALITCTPGMDWAVSVDTLVSGRHFFLDIEPSTLGHKVLAVNLSDMAAMGATPR
WITLSLTLTETLAQDDAWLKAFSSGFFALADQYQIELIGGDTTSGPLNIGVQIIGEVEQGKALRRSDAKPGDDIWVSGFL
GDAALALQFLQQRITLTEQEATPCLIALYTPTPRVVLGKALVNVAHSAIDISDGLLADLGHILERSDVAATVDFDRIPCS
PALKNKLQQENATRQLAIDCLLSGGDDYELCFTAPENRHDVIAQLAQQTGVKLSRIGKIVPGKGLAVLNANDNPLIFNNK
GYDHFLTR

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=329, Percent_Identity=45.5927051671732, Blast_Score=260, Evalue=8e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35458; Mature: 35458

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00732 RIBOSOMAL_S16

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSEFDIINRYFSRPVRNALLGPGDDAALITCTPGMDWAVSVDTLVSGRHFFLDIEPSTL
CCCCHHHHHHHHCCHHHHHHCCCCCCCEEEEECCCCCEEEEHHHEECCCEEEEEECCCCC
GHKVLAVNLSDMAAMGATPRWITLSLTLTETLAQDDAWLKAFSSGFFALADQYQIELIGG
CCEEEEEEHHHHHHCCCCCCEEEEEEEEEHHHHCCHHHHHHHHCCCEEEECCEEEEEEEC
DTTSGPLNIGVQIIGEVEQGKALRRSDAKPGDDIWVSGFLGDAALALQFLQQRITLTEQE
CCCCCCEEEEEEEEEEHHHCCHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCC
ATPCLIALYTPTPRVVLGKALVNVAHSAIDISDGLLADLGHILERSDVAATVDFDRIPCS
CCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCC
PALKNKLQQENATRQLAIDCLLSGGDDYELCFTAPENRHDVIAQLAQQTGVKLSRIGKIV
HHHHHHHHHHCCHHHEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHCCCC
PGKGLAVLNANDNPLIFNNKGYDHFLTR
CCCCEEEEECCCCEEEECCCCCHHHCCC
>Mature Secondary Structure
MNSEFDIINRYFSRPVRNALLGPGDDAALITCTPGMDWAVSVDTLVSGRHFFLDIEPSTL
CCCCHHHHHHHHCCHHHHHHCCCCCCCEEEEECCCCCEEEEHHHEECCCEEEEEECCCCC
GHKVLAVNLSDMAAMGATPRWITLSLTLTETLAQDDAWLKAFSSGFFALADQYQIELIGG
CCEEEEEEHHHHHHCCCCCCEEEEEEEEEHHHHCCHHHHHHHHCCCEEEECCEEEEEEEC
DTTSGPLNIGVQIIGEVEQGKALRRSDAKPGDDIWVSGFLGDAALALQFLQQRITLTEQE
CCCCCCEEEEEEEEEEHHHCCHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCC
ATPCLIALYTPTPRVVLGKALVNVAHSAIDISDGLLADLGHILERSDVAATVDFDRIPCS
CCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCCCC
PALKNKLQQENATRQLAIDCLLSGGDDYELCFTAPENRHDVIAQLAQQTGVKLSRIGKIV
HHHHHHHHHHCCHHHEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHCCCC
PGKGLAVLNANDNPLIFNNKGYDHFLTR
CCCCEEEEECCCCEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]