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The map label for this gene is ubiG [H]

Identifier: 114332454

GI number: 114332454

Start: 2635667

End: 2636425

Strand: Reverse

Name: ubiG [H]

Synonym: Neut_2507

Alternate gene names: 114332454

Gene position: 2636425-2635667 (Counterclockwise)

Preceding gene: 114332455

Following gene: 114332453

Centisome position: 99.07

GC content: 44.27

Gene sequence:

>759_bases
ATGCAGTTATTGACAAAAGTATCTTTTCAGTTAAATTTGCAGGCAAATTATTGTATGAAAAATGATGGCATCAACGCAGA
TCCAATGGAACTGGAGAAATTCAGTCAACTGGCGCATCACTGGTGGGATCCAAACAGTGAATTCAAACCGTTGCATGAAA
TCAATCCACTTCGGTTGAACTATATTGACGAAATTGCAGGGTTGGATGGAAAAACAGTTGTCGATGTCGGTTGTGGCGGC
GGGATATTATCCGAATCCATGGCAGCACGTGGTGCCAGGGTGACGGGGATTGACCTGAGCGACAAGGCGCTGAAAGTAGC
AAAATTACATCTTCTGGAAAGTGGTCATCAGGTTGATTATCGTAAAATAACTGTGGAAGCGCTTGCGGTGGAACTTCCTC
AGCATTATGACATTGTTACCTGCATGGAGATGCTGGAACATGTACCGGATCCTGCCAGCGTCATTCAATCATGTGCCCGT
CTTGTAAAAAATGGTGGATGGGTATTTTTTTCGACCTTGAACCGTAATCTGAAAGCGTATCTTTATGCCATCATTGGTGC
TGAATATATTCTTCGATTGCTGCCACGAGGAACGCATGAGTACGCAAAATTTATTAAACCTTCTGAACTGGCGCGCATGG
CGCGTACTGCCGGATTGATAGAGTCCGGGATTATCGGTATGACCTACAATCCAATCACAAAAATCTATGCTCTGGAAGCT
GATACCAGTGTCAACTACATCATGACATTCCAAGCCTGA

Upstream 100 bases:

>100_bases
AAAGTGACCCTGTCCTGTCCGATTAATCATTGATCGTTCAAGCGGATATTGCTGGGTAATCGAGAACTTGATACCCTGAA
CAAAGCTAAACTGTACAGGG

Downstream 100 bases:

>100_bases
TTTAATACAAGCACATCAAATATTCCTGATGATCAGAAAAGCTGTCCTGTTCGATTTCGACGGCACCATTGCGGACACAG
CACCGGATCTTGGCCGCGCA

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MQLLTKVSFQLNLQANYCMKNDGINADPMELEKFSQLAHHWWDPNSEFKPLHEINPLRLNYIDEIAGLDGKTVVDVGCGG
GILSESMAARGARVTGIDLSDKALKVAKLHLLESGHQVDYRKITVEALAVELPQHYDIVTCMEMLEHVPDPASVIQSCAR
LVKNGGWVFFSTLNRNLKAYLYAIIGAEYILRLLPRGTHEYAKFIKPSELARMARTAGLIESGIIGMTYNPITKIYALEA
DTSVNYIMTFQA

Sequences:

>Translated_252_residues
MQLLTKVSFQLNLQANYCMKNDGINADPMELEKFSQLAHHWWDPNSEFKPLHEINPLRLNYIDEIAGLDGKTVVDVGCGG
GILSESMAARGARVTGIDLSDKALKVAKLHLLESGHQVDYRKITVEALAVELPQHYDIVTCMEMLEHVPDPASVIQSCAR
LVKNGGWVFFSTLNRNLKAYLYAIIGAEYILRLLPRGTHEYAKFIKPSELARMARTAGLIESGIIGMTYNPITKIYALEA
DTSVNYIMTFQA
>Mature_252_residues
MQLLTKVSFQLNLQANYCMKNDGINADPMELEKFSQLAHHWWDPNSEFKPLHEINPLRLNYIDEIAGLDGKTVVDVGCGG
GILSESMAARGARVTGIDLSDKALKVAKLHLLESGHQVDYRKITVEALAVELPQHYDIVTCMEMLEHVPDPASVIQSCAR
LVKNGGWVFFSTLNRNLKAYLYAIIGAEYILRLLPRGTHEYAKFIKPSELARMARTAGLIESGIIGMTYNPITKIYALEA
DTSVNYIMTFQA

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=236, Percent_Identity=33.8983050847458, Blast_Score=156, Evalue=2e-38,
Organism=Escherichia coli, GI1788564, Length=228, Percent_Identity=59.2105263157895, Blast_Score=269, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI115533050, Length=233, Percent_Identity=33.9055793991416, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324476, Length=238, Percent_Identity=32.3529411764706, Blast_Score=116, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24585589, Length=232, Percent_Identity=31.8965517241379, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI281365311, Length=220, Percent_Identity=32.7272727272727, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 28130; Mature: 28130

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLTKVSFQLNLQANYCMKNDGINADPMELEKFSQLAHHWWDPNSEFKPLHEINPLRLN
CCCCEEEEEEEEEEECEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEH
YIDEIAGLDGKTVVDVGCGGGILSESMAARGARVTGIDLSDKALKVAKLHLLESGHQVDY
HHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCCH
RKITVEALAVELPQHYDIVTCMEMLEHVPDPASVIQSCARLVKNGGWVFFSTLNRNLKAY
HEEHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHH
LYAIIGAEYILRLLPRGTHEYAKFIKPSELARMARTAGLIESGIIGMTYNPITKIYALEA
HHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEC
DTSVNYIMTFQA
CCCCEEEEEECC
>Mature Secondary Structure
MQLLTKVSFQLNLQANYCMKNDGINADPMELEKFSQLAHHWWDPNSEFKPLHEINPLRLN
CCCCEEEEEEEEEEECEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCEEEH
YIDEIAGLDGKTVVDVGCGGGILSESMAARGARVTGIDLSDKALKVAKLHLLESGHQVDY
HHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCCH
RKITVEALAVELPQHYDIVTCMEMLEHVPDPASVIQSCARLVKNGGWVFFSTLNRNLKAY
HEEHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHH
LYAIIGAEYILRLLPRGTHEYAKFIKPSELARMARTAGLIESGIIGMTYNPITKIYALEA
HHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEEC
DTSVNYIMTFQA
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]