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The map label for this gene is comM [H]

Identifier: 114332334

GI number: 114332334

Start: 2493389

End: 2494888

Strand: Direct

Name: comM [H]

Synonym: Neut_2377

Alternate gene names: 114332334

Gene position: 2493389-2494888 (Clockwise)

Preceding gene: 114332333

Following gene: 114332344

Centisome position: 93.7

GC content: 52.93

Gene sequence:

>1500_bases
ATGTCTCTGGCTATTCTGTATAGCCGTGCATTGTGTGGAGTGGACGCGCCGCTAGTGACCGTAGAGGTGCATCTTGCTAA
CGGTTTACCAAAATTTACTATCGTTGGGCTTCCGGAAACGGAAGTCAGGGAAAGTAAAGACAGGGTGCGCGCCGCACTGC
AGAATGGACGATTCAAATTTCCTGCCCGGCGTATTACGGTTAATCTTGCACCGGCTGATTTACCCAAGGAAAGCGGGCGT
TTCGATTTGCCTATCGCGCTGGGCATCTTAGCGGCAACCGGGCAGATTCCTGCAAATAAACTCGATCAGTATGAATGGGC
AGGGGAGTTGTCTCTTGATGGTCGCCTGCGCCCGATTCGTGGCGCACTGGCCATGACTTACAGTGCCTCCCGTTCAGGCC
GCAGTTTCGTTTTGCCAGAGCAAAATGCCGGCGAAGCAGCACTGGTCAAAGAGGCGACTATCTATCCTGCTGCTTCGCTG
CTGCAGCTGTGTGCATATCTGACTGGGCAGGAGCCATGGCAACCTTATCGTGGTGGATCGGCTGAGTTAGAATCAAATGA
TTATCCGGACATGGGAGATGTCAAAGGGCAGATGCAGGCCAGGCGCGCGTTGGAGATCGCTGCTGCAGGTGGACACAGTG
TGCTGATGATTGGCCCACCGGGCACGGGAAAAACCATGTTAGCCAAGCGTATCCCGGGAATTTTGCCGCCCATGACCGGA
CAGGAGGCGCTGGAATCGGCTGCCATTCAATCTTTGGGGAGTGGCAGTTTTGATCTGGCTAACTGGAAGCGTCGCCCGTT
TCGGTCACCCCATCATACTGCCTCGGCCGTGGCATTGGTGGGTGGGGGCAGTATTCCACGCCCGGGTGAGATTTCACTGG
CCATGCATGGAGTGCTGTTTCTTGATGAGTTACCCGAATTTGATCGGCGGGTTCTGGAGGTGCTGCGTGAACCGCTTGAA
TCCGGTCACATTACCATTTCACGCGCTGCACGCCGAGCAGATTTTCCAGCCAGATTTCAACTTATTGCTGCAATGAACCC
ATGTCCATGCGGGTATTTGGGGCATTACACCAATAAATGTCGTTGTACACCTGATCAGGTAGCGCGTTATCGTGGCAAGG
TTTCCGGTCCGTTGCTGGATCGAATCGATATTCAGATTGAAGTCCCTGCTTTGCCGAAGGAGGATATGTTGCGCCCCGGT
CCGGGTGAATCCAGCGCTGTTATTCGAGAACGAACGTTGGTTGCCCGGCAACGTCAGTTAAATCGTCAACACGTACCCAA
TACGAGGTTAGGGGTGCAGGAAATTGAAAAATATTGTGTTCTGGATGCGGAGGGGAAGCGTATGCTGGAACGAGCCATGA
CCCATTTGAATATCTCAGCACGGGCTTATCACAGAATACTGAAGCTGGCTCGAACCATTGCAGATTTGTCAGGCAGTAAA
CCTATTTTGGGAAAGCATGTGGCGGAAGCTATTCAGTACCGCCGTATGGGTATAAATTAA

Upstream 100 bases:

>100_bases
ATACTTCTGGCCCCGGATCGGCCAATGACAGGTAGTGCTGAGATTTGTTACATTTTTTCTGGTGAAGCACTGGCTCACCA
TGCTTTGATCGTGTTCCTTT

Downstream 100 bases:

>100_bases
TTGTTCGGACAGGTTGAATCAGTAATAGTCAGCGGTACGTGCACAATTTTCAAATCTTGTAAATTCGCCCAGAAAAGTCA
GATCAACTTTGCCAATCGGC

Product: Mg chelatase, subunit ChlI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MSLAILYSRALCGVDAPLVTVEVHLANGLPKFTIVGLPETEVRESKDRVRAALQNGRFKFPARRITVNLAPADLPKESGR
FDLPIALGILAATGQIPANKLDQYEWAGELSLDGRLRPIRGALAMTYSASRSGRSFVLPEQNAGEAALVKEATIYPAASL
LQLCAYLTGQEPWQPYRGGSAELESNDYPDMGDVKGQMQARRALEIAAAGGHSVLMIGPPGTGKTMLAKRIPGILPPMTG
QEALESAAIQSLGSGSFDLANWKRRPFRSPHHTASAVALVGGGSIPRPGEISLAMHGVLFLDELPEFDRRVLEVLREPLE
SGHITISRAARRADFPARFQLIAAMNPCPCGYLGHYTNKCRCTPDQVARYRGKVSGPLLDRIDIQIEVPALPKEDMLRPG
PGESSAVIRERTLVARQRQLNRQHVPNTRLGVQEIEKYCVLDAEGKRMLERAMTHLNISARAYHRILKLARTIADLSGSK
PILGKHVAEAIQYRRMGIN

Sequences:

>Translated_499_residues
MSLAILYSRALCGVDAPLVTVEVHLANGLPKFTIVGLPETEVRESKDRVRAALQNGRFKFPARRITVNLAPADLPKESGR
FDLPIALGILAATGQIPANKLDQYEWAGELSLDGRLRPIRGALAMTYSASRSGRSFVLPEQNAGEAALVKEATIYPAASL
LQLCAYLTGQEPWQPYRGGSAELESNDYPDMGDVKGQMQARRALEIAAAGGHSVLMIGPPGTGKTMLAKRIPGILPPMTG
QEALESAAIQSLGSGSFDLANWKRRPFRSPHHTASAVALVGGGSIPRPGEISLAMHGVLFLDELPEFDRRVLEVLREPLE
SGHITISRAARRADFPARFQLIAAMNPCPCGYLGHYTNKCRCTPDQVARYRGKVSGPLLDRIDIQIEVPALPKEDMLRPG
PGESSAVIRERTLVARQRQLNRQHVPNTRLGVQEIEKYCVLDAEGKRMLERAMTHLNISARAYHRILKLARTIADLSGSK
PILGKHVAEAIQYRRMGIN
>Mature_498_residues
SLAILYSRALCGVDAPLVTVEVHLANGLPKFTIVGLPETEVRESKDRVRAALQNGRFKFPARRITVNLAPADLPKESGRF
DLPIALGILAATGQIPANKLDQYEWAGELSLDGRLRPIRGALAMTYSASRSGRSFVLPEQNAGEAALVKEATIYPAASLL
QLCAYLTGQEPWQPYRGGSAELESNDYPDMGDVKGQMQARRALEIAAAGGHSVLMIGPPGTGKTMLAKRIPGILPPMTGQ
EALESAAIQSLGSGSFDLANWKRRPFRSPHHTASAVALVGGGSIPRPGEISLAMHGVLFLDELPEFDRRVLEVLREPLES
GHITISRAARRADFPARFQLIAAMNPCPCGYLGHYTNKCRCTPDQVARYRGKVSGPLLDRIDIQIEVPALPKEDMLRPGP
GESSAVIRERTLVARQRQLNRQHVPNTRLGVQEIEKYCVLDAEGKRMLERAMTHLNISARAYHRILKLARTIADLSGSKP
ILGKHVAEAIQYRRMGIN

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=500, Percent_Identity=52, Blast_Score=508, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 54496; Mature: 54365

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAILYSRALCGVDAPLVTVEVHLANGLPKFTIVGLPETEVRESKDRVRAALQNGRFKF
CCEEEEEHHHHHCCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEC
PARRITVNLAPADLPKESGRFDLPIALGILAATGQIPANKLDQYEWAGELSLDGRLRPIR
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCEECCCCCCHHH
GALAMTYSASRSGRSFVLPEQNAGEAALVKEATIYPAASLLQLCAYLTGQEPWQPYRGGS
HHEEEEEECCCCCCEEECCCCCCCCEEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCC
AELESNDYPDMGDVKGQMQARRALEIAAAGGHSVLMIGPPGTGKTMLAKRIPGILPPMTG
CCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCCCC
QEALESAAIQSLGSGSFDLANWKRRPFRSPHHTASAVALVGGGSIPRPGEISLAMHGVLF
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEHHHHHHHH
LDELPEFDRRVLEVLREPLESGHITISRAARRADFPARFQLIAAMNPCPCGYLGHYTNKC
HHHCCHHHHHHHHHHHHHHHCCCEEEEHHHHHCCCCHHEEEEEECCCCCCCHHHCCCCCC
RCTPDQVARYRGKVSGPLLDRIDIQIEVPALPKEDMLRPGPGESSAVIRERTLVARQRQL
CCCHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHH
NRQHVPNTRLGVQEIEKYCVLDAEGKRMLERAMTHLNISARAYHRILKLARTIADLSGSK
HHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
PILGKHVAEAIQYRRMGIN
CHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLAILYSRALCGVDAPLVTVEVHLANGLPKFTIVGLPETEVRESKDRVRAALQNGRFKF
CEEEEEHHHHHCCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEC
PARRITVNLAPADLPKESGRFDLPIALGILAATGQIPANKLDQYEWAGELSLDGRLRPIR
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCEECCCCCCHHH
GALAMTYSASRSGRSFVLPEQNAGEAALVKEATIYPAASLLQLCAYLTGQEPWQPYRGGS
HHEEEEEECCCCCCEEECCCCCCCCEEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCC
AELESNDYPDMGDVKGQMQARRALEIAAAGGHSVLMIGPPGTGKTMLAKRIPGILPPMTG
CCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCCCC
QEALESAAIQSLGSGSFDLANWKRRPFRSPHHTASAVALVGGGSIPRPGEISLAMHGVLF
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEHHHHHHHH
LDELPEFDRRVLEVLREPLESGHITISRAARRADFPARFQLIAAMNPCPCGYLGHYTNKC
HHHCCHHHHHHHHHHHHHHHCCCEEEEHHHHHCCCCHHEEEEEECCCCCCCHHHCCCCCC
RCTPDQVARYRGKVSGPLLDRIDIQIEVPALPKEDMLRPGPGESSAVIRERTLVARQRQL
CCCHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHH
NRQHVPNTRLGVQEIEKYCVLDAEGKRMLERAMTHLNISARAYHRILKLARTIADLSGSK
HHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
PILGKHVAEAIQYRRMGIN
CHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]