Click here to switch to the map view.

The map label for this gene is ahpC [H]

Identifier: 114332323

GI number: 114332323

Start: 2483526

End: 2484089

Strand: Direct

Name: ahpC [H]

Synonym: Neut_2366

Alternate gene names: 114332323

Gene position: 2483526-2484089 (Clockwise)

Preceding gene: 114332322

Following gene: 114332324

Centisome position: 93.33

GC content: 45.57

Gene sequence:

>564_bases
ATGTCACTGATTAACACTACTATTAAACCGTTCAAGGCAACTGCATACCACAATGGCGATTTTGTTGAGGTATCCGACAA
AACATTAAAGGGCAAATGGTCGGTTATCGTTTTCTATCCAGCCGACTTTACTTTTGTATGCCCAACCGAGCTGGAGGATC
TGGCAGATAATTATGCTGAGTTCCAGAAAGCAGGCATTGAAGTCTATTCGGTTTCTACCGACACACATTTCACACACAAA
GCATGGCACGACAGCTCCAGCGTGGTGCGTAAGGTTCAATATCCCATGATAGGCGATCCAACCAGACAGCTGGCACGCGA
CTTTGACGTACTCATTGAAGAAGAAGGATTAGCCTTACGTGGAAGTTTTATTATCAATCCAGAAGGCCAAATTAAAGCAC
TAGAAGTTCAGGATCTCAGTATCGGTCGTAATGCTGCTGAATTACTGCGCAAGGCTAAGGCTGCACAATACGTCTCTACT
CACTCGGGCGAAGTTTGCCCTGCCAAATGGACTGATGGTGCTGCCACGCTGAAGCCATCTATTGATCTGGTTGGCAAGAT
TTAA

Upstream 100 bases:

>100_bases
TACTGGTCACATTCATTGTGGACTAGACTAATTTGATACAGCGTTCTAAACTTCTGTCAAAGCTTATTATTCTGAGTCAA
CTACATAAAAGGAAGCGGCA

Downstream 100 bases:

>100_bases
ATATTCTGCACAATTCTGCTTTCAACCGGCTGCAGCGATACTTCTCCTCTAGAGAGGTATCCCAGCCGGTTTCTTCAGAC
CAGCCAATCACACAATGATG

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLINTTIKPFKATAYHNGDFVEVSDKTLKGKWSVIVFYPADFTFVCPTELEDLADNYAEFQKAGIEVYSVSTDTHFTHK
AWHDSSSVVRKVQYPMIGDPTRQLARDFDVLIEEEGLALRGSFIINPEGQIKALEVQDLSIGRNAAELLRKAKAAQYVST
HSGEVCPAKWTDGAATLKPSIDLVGKI

Sequences:

>Translated_187_residues
MSLINTTIKPFKATAYHNGDFVEVSDKTLKGKWSVIVFYPADFTFVCPTELEDLADNYAEFQKAGIEVYSVSTDTHFTHK
AWHDSSSVVRKVQYPMIGDPTRQLARDFDVLIEEEGLALRGSFIINPEGQIKALEVQDLSIGRNAAELLRKAKAAQYVST
HSGEVCPAKWTDGAATLKPSIDLVGKI
>Mature_186_residues
SLINTTIKPFKATAYHNGDFVEVSDKTLKGKWSVIVFYPADFTFVCPTELEDLADNYAEFQKAGIEVYSVSTDTHFTHKA
WHDSSSVVRKVQYPMIGDPTRQLARDFDVLIEEEGLALRGSFIINPEGQIKALEVQDLSIGRNAAELLRKAKAAQYVSTH
SGEVCPAKWTDGAATLKPSIDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=49.7109826589595, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=49.7109826589595, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=45.1428571428571, Blast_Score=157, Evalue=6e-39,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=42.2857142857143, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=42.2857142857143, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=42.2857142857143, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=39.4444444444444, Blast_Score=139, Evalue=1e-33,
Organism=Homo sapiens, GI33188454, Length=74, Percent_Identity=51.3513513513513, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI4758638, Length=161, Percent_Identity=27.9503105590062, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=64.1711229946524, Blast_Score=267, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17554494, Length=179, Percent_Identity=42.4581005586592, Blast_Score=155, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=43.1034482758621, Blast_Score=153, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=41.5300546448087, Blast_Score=153, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=28.0487804878049, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=178, Percent_Identity=42.6966292134831, Blast_Score=146, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6323613, Length=178, Percent_Identity=42.6966292134831, Blast_Score=145, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6319407, Length=163, Percent_Identity=30.0613496932515, Blast_Score=78, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=41.8079096045198, Blast_Score=157, Evalue=5e-39,
Organism=Drosophila melanogaster, GI21357347, Length=189, Percent_Identity=40.7407407407407, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=41.7582417582418, Blast_Score=149, Evalue=8e-37,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=41.7582417582418, Blast_Score=149, Evalue=8e-37,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=41.7647058823529, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=41.7647058823529, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=32.9113924050633, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17975518, Length=156, Percent_Identity=33.974358974359, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24652436, Length=156, Percent_Identity=33.974358974359, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24652434, Length=156, Percent_Identity=33.974358974359, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20711; Mature: 20579

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINTTIKPFKATAYHNGDFVEVSDKTLKGKWSVIVFYPADFTFVCPTELEDLADNYAE
CCCCCCCCCCEEEEEEECCCEEEECCCEECCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKAGIEVYSVSTDTHFTHKAWHDSSSVVRKVQYPMIGDPTRQLARDFDVLIEEEGLALR
HHHCCEEEEEEECCCCEEEHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCCEEEE
GSFIINPEGQIKALEVQDLSIGRNAAELLRKAKAAQYVSTHSGEVCPAKWTDGAATLKPS
CEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCC
IDLVGKI
EEEEECC
>Mature Secondary Structure 
SLINTTIKPFKATAYHNGDFVEVSDKTLKGKWSVIVFYPADFTFVCPTELEDLADNYAE
CCCCCCCCCEEEEEEECCCEEEECCCEECCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKAGIEVYSVSTDTHFTHKAWHDSSSVVRKVQYPMIGDPTRQLARDFDVLIEEEGLALR
HHHCCEEEEEEECCCCEEEHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCCEEEE
GSFIINPEGQIKALEVQDLSIGRNAAELLRKAKAAQYVSTHSGEVCPAKWTDGAATLKPS
CEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCC
IDLVGKI
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]