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The map label for this gene is infC [H]

Identifier: 114332290

GI number: 114332290

Start: 2455386

End: 2455874

Strand: Reverse

Name: infC [H]

Synonym: Neut_2330

Alternate gene names: 114332290

Gene position: 2455874-2455386 (Counterclockwise)

Preceding gene: 114332291

Following gene: 114332289

Centisome position: 92.29

GC content: 43.56

Gene sequence:

>489_bases
TTGATTGGCGTGAACGGTGAGCAGGTGGGGATAGTACCAATAGCTGAAGCAAAAGAGTTGGCTGAAGAGTCTGGTGTAGA
TATTGTAGAAATTGCACCAAGTGCGGAGCCTCCAGTTTGCAGGTTGATGGATTATGGAAAATATCTTTATCAGGAAAGCA
AAAAGAAGCACGATGCCAAGCTGAGGCAAAAACAGATACAGGTAAAAGAGATTAAACTCAGACCCAATACAGATGAGGGT
GATTATAGTATTAAGCTGCGGAATTTAATCAATTTCTTAAATGAAGGCGACAAGGTTAAAGTTACACTCCGGTTCCGTGG
AAGGGAGATGGCGCATCAGGAATTTGGTATTAGACTGCTTGAAAGGGTAAGAGAAGAACTTGAGGAGCATGCCGTTGTTG
AGCAGTTTCCTAGATTGGAAGGACGGCAGATGGTGATGGTTCTGGCGCCTAGAAAAAAAGAGGTGAAGGTGGCCAAATCT
GATAAGTAG

Upstream 100 bases:

>100_bases
AAGAGTGTAATTAAGGGGTTTTTATGGATTTACGGAGGGTACCATAGCTCAAGAAAAGACTGTAAGGGTTAATGATGAAA
TCACGGCACTACAAGTCAGA

Downstream 100 bases:

>100_bases
CGGGAAGCGGATACAAAAAACGAAACTGTAACTTAGTAAGTAGCGAATTATCTTGCTGCCGTAAAATATGTTCTTGCTGG
TTTATTTAAAATAAGTGATA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MIGVNGEQVGIVPIAEAKELAEESGVDIVEIAPSAEPPVCRLMDYGKYLYQESKKKHDAKLRQKQIQVKEIKLRPNTDEG
DYSIKLRNLINFLNEGDKVKVTLRFRGREMAHQEFGIRLLERVREELEEHAVVEQFPRLEGRQMVMVLAPRKKEVKVAKS
DK

Sequences:

>Translated_162_residues
MIGVNGEQVGIVPIAEAKELAEESGVDIVEIAPSAEPPVCRLMDYGKYLYQESKKKHDAKLRQKQIQVKEIKLRPNTDEG
DYSIKLRNLINFLNEGDKVKVTLRFRGREMAHQEFGIRLLERVREELEEHAVVEQFPRLEGRQMVMVLAPRKKEVKVAKS
DK
>Mature_162_residues
MIGVNGEQVGIVPIAEAKELAEESGVDIVEIAPSAEPPVCRLMDYGKYLYQESKKKHDAKLRQKQIQVKEIKLRPNTDEG
DYSIKLRNLINFLNEGDKVKVTLRFRGREMAHQEFGIRLLERVREELEEHAVVEQFPRLEGRQMVMVLAPRKKEVKVAKS
DK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=155, Percent_Identity=65.8064516129032, Blast_Score=202, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18653; Mature: 18653

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGVNGEQVGIVPIAEAKELAEESGVDIVEIAPSAEPPVCRLMDYGKYLYQESKKKHDAK
CCCCCCCEEEEEECHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRQKQIQVKEIKLRPNTDEGDYSIKLRNLINFLNEGDKVKVTLRFRGREMAHQEFGIRLL
HHHHHHHEEEEEECCCCCCCCEEEEHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHH
ERVREELEEHAVVEQFPRLEGRQMVMVLAPRKKEVKVAKSDK
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEECCCCC
>Mature Secondary Structure
MIGVNGEQVGIVPIAEAKELAEESGVDIVEIAPSAEPPVCRLMDYGKYLYQESKKKHDAK
CCCCCCCEEEEEECHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRQKQIQVKEIKLRPNTDEGDYSIKLRNLINFLNEGDKVKVTLRFRGREMAHQEFGIRLL
HHHHHHHEEEEEECCCCCCCCEEEEHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHH
ERVREELEEHAVVEQFPRLEGRQMVMVLAPRKKEVKVAKSDK
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]