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The map label for this gene is lppB [H]

Identifier: 114332282

GI number: 114332282

Start: 2447358

End: 2448344

Strand: Reverse

Name: lppB [H]

Synonym: Neut_2322

Alternate gene names: 114332282

Gene position: 2448344-2447358 (Counterclockwise)

Preceding gene: 114332283

Following gene: 114332279

Centisome position: 92.01

GC content: 41.64

Gene sequence:

>987_bases
ATGTTCATGCAAATAATTCTTTTATTTCTTGTCCTGTCCTTGGGTGCTTGTGTTTCAAAGCCTGACCCCGCGCCAATCGT
TGAGCGACAGCTTGGTCGTTATTCTGATGAAGGGAATAATGCTACAAAAGGTCTTTTAGATAGAAAAACCTACATAGTGC
AAAGTGGTGATACTTTGTATAGTATTGCTCTCAGACATGGTTTGGATATTAATCAGTTGGCTGGGATAAATAATATTACA
GATCCCAGGGAGTTGCGGGTTGGCCAAGAGCTTTATTTGCAGACACTTCCTGCAGAAGGATTAATTTCTCAACAGGAAAG
CCTTACCTCTCAACCTACGCTTTACTCAATAGCTCAACCCGAGGATGTGGGTGTAGTAACTGGTGGCTATCAACCTGGTT
TTTCTGAGACTGGGGAGAAGGCATCTGAATCTTTCAAGACAGAACCAAAAGGGGTTTTGCTGCCTTATTCGGATTCGGCT
CGTGATCAGCTGAATAATCAATCTAAAACTGTATCGGCCCAGAAATTAGCTGAAAAAAATTCAGATTCTTATCAAGTTGG
CAGTGTCGGAGGGGGAGGTAACAGCGATCCTGGTCAATCAATAAGTGTGAGTGCAAATAAGAGTGGCATTAATTGGGGGT
GGCCGGCAGATGGACAAATAATAAGCAGATTTTCTGAAAAATCAAAAGGTGTGGGAATAAGTGGCAGTTTTAAGCAACCA
GTTCTGGCATCAGCTTCTGGGACAGTAGTTTATAGTGGTAACGGTTTGCGCGGATATGGCAACTTAATTATTATTAAGCA
TAATGATAGTTATTTGAGTGCTTATGGGCATAACAGTAAAATCTTTGTGCATGAGGGGGAGAATGTTTCTAAAGGACAGA
AAATTGCTGAAATGGGTAATACTGATGGTGGCGTGGTAAAACTTCATTTCGAAATTCGTGAAAAGGGTAAGCCTGTAGAT
CCTCTTGGCTATTTGCCTGTTCGATAG

Upstream 100 bases:

>100_bases
TAGAGGCAGTCATGTTGTTGGCTGTATCTTAAACTTTCAATTTCTTATTTTCTATAGCAATTTAATCTAAATGTGGCGGA
TAGCGTAGAGCTAAATATCT

Downstream 100 bases:

>100_bases
CTATTGTCTATGTAGTAGATATAAATCAAATCAAATCAAATCAAATCAAATCAAATTGGAGTTCTTCGGTTTAGATTAAT
GAGCGTTTGGACACTTAATG

Product: peptidase M23B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MFMQIILLFLVLSLGACVSKPDPAPIVERQLGRYSDEGNNATKGLLDRKTYIVQSGDTLYSIALRHGLDINQLAGINNIT
DPRELRVGQELYLQTLPAEGLISQQESLTSQPTLYSIAQPEDVGVVTGGYQPGFSETGEKASESFKTEPKGVLLPYSDSA
RDQLNNQSKTVSAQKLAEKNSDSYQVGSVGGGGNSDPGQSISVSANKSGINWGWPADGQIISRFSEKSKGVGISGSFKQP
VLASASGTVVYSGNGLRGYGNLIIIKHNDSYLSAYGHNSKIFVHEGENVSKGQKIAEMGNTDGGVVKLHFEIREKGKPVD
PLGYLPVR

Sequences:

>Translated_328_residues
MFMQIILLFLVLSLGACVSKPDPAPIVERQLGRYSDEGNNATKGLLDRKTYIVQSGDTLYSIALRHGLDINQLAGINNIT
DPRELRVGQELYLQTLPAEGLISQQESLTSQPTLYSIAQPEDVGVVTGGYQPGFSETGEKASESFKTEPKGVLLPYSDSA
RDQLNNQSKTVSAQKLAEKNSDSYQVGSVGGGGNSDPGQSISVSANKSGINWGWPADGQIISRFSEKSKGVGISGSFKQP
VLASASGTVVYSGNGLRGYGNLIIIKHNDSYLSAYGHNSKIFVHEGENVSKGQKIAEMGNTDGGVVKLHFEIREKGKPVD
PLGYLPVR
>Mature_328_residues
MFMQIILLFLVLSLGACVSKPDPAPIVERQLGRYSDEGNNATKGLLDRKTYIVQSGDTLYSIALRHGLDINQLAGINNIT
DPRELRVGQELYLQTLPAEGLISQQESLTSQPTLYSIAQPEDVGVVTGGYQPGFSETGEKASESFKTEPKGVLLPYSDSA
RDQLNNQSKTVSAQKLAEKNSDSYQVGSVGGGGNSDPGQSISVSANKSGINWGWPADGQIISRFSEKSKGVGISGSFKQP
VLASASGTVVYSGNGLRGYGNLIIIKHNDSYLSAYGHNSKIFVHEGENVSKGQKIAEMGNTDGGVVKLHFEIREKGKPVD
PLGYLPVR

Specific function: May be a virulence determinant [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 LysM repeat [H]

Homologues:

Organism=Escherichia coli, GI1789099, Length=311, Percent_Identity=38.9067524115756, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87082174, Length=118, Percent_Identity=49.1525423728814, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082297, Length=119, Percent_Identity=35.2941176470588, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047
- InterPro:   IPR002886
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 35123; Mature: 35123

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMQIILLFLVLSLGACVSKPDPAPIVERQLGRYSDEGNNATKGLLDRKTYIVQSGDTLY
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCHHHHHHCCEEEEEECCCCEE
SIALRHGLDINQLAGINNITDPRELRVGQELYLQTLPAEGLISQQESLTSQPTLYSIAQP
EHHHHHCCCHHHHCCCCCCCCHHHHHCCHHHHHEECCCCHHHHHHHHHCCCCCEEEECCC
EDVGVVTGGYQPGFSETGEKASESFKTEPKGVLLPYSDSARDQLNNQSKTVSAQKLAEKN
CCCEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCHHHHHHHHHHHCC
SDSYQVGSVGGGGNSDPGQSISVSANKSGINWGWPADGQIISRFSEKSKGVGISGSFKQP
CCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
VLASASGTVVYSGNGLRGYGNLIIIKHNDSYLSAYGHNSKIFVHEGENVSKGQKIAEMGN
EEECCCCEEEECCCCCCCCCCEEEEEECCCEEEECCCCCEEEEECCCCCCHHHHHHHCCC
TDGGVVKLHFEIREKGKPVDPLGYLPVR
CCCCEEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MFMQIILLFLVLSLGACVSKPDPAPIVERQLGRYSDEGNNATKGLLDRKTYIVQSGDTLY
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCHHHHHHCCEEEEEECCCCEE
SIALRHGLDINQLAGINNITDPRELRVGQELYLQTLPAEGLISQQESLTSQPTLYSIAQP
EHHHHHCCCHHHHCCCCCCCCHHHHHCCHHHHHEECCCCHHHHHHHHHCCCCCEEEECCC
EDVGVVTGGYQPGFSETGEKASESFKTEPKGVLLPYSDSARDQLNNQSKTVSAQKLAEKN
CCCEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCHHHHHHHHHHHCC
SDSYQVGSVGGGGNSDPGQSISVSANKSGINWGWPADGQIISRFSEKSKGVGISGSFKQP
CCCEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
VLASASGTVVYSGNGLRGYGNLIIIKHNDSYLSAYGHNSKIFVHEGENVSKGQKIAEMGN
EEECCCCEEEECCCCCCCCCCEEEEEECCCEEEECCCCCEEEEECCCCCCHHHHHHHCCC
TDGGVVKLHFEIREKGKPVDPLGYLPVR
CCCCEEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]