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The map label for this gene is lptA [H]

Identifier: 114332261

GI number: 114332261

Start: 2426736

End: 2427287

Strand: Direct

Name: lptA [H]

Synonym: Neut_2301

Alternate gene names: 114332261

Gene position: 2426736-2427287 (Clockwise)

Preceding gene: 114332260

Following gene: 114332262

Centisome position: 91.19

GC content: 46.74

Gene sequence:

>552_bases
ATGCAATCTCAATGTTTGTTCCTAAGCTTGTCTCTCATGTTTTTCTCAGCCACTGCCCTGGCTGAACGCGCAGATCGCGA
TAAGCCAATTCATCTGGAAGCCGATCGCGCAACTGTCGAAGATTACAAGCAAAAAGGGGAGTTTCGTACCAGCATATTTA
CCGGGAATGTCATATTGACCCAGGGAACGCTTATTCTTCGTGCAGATAAAGTCGTGATGAAGGAGGACAGCACGGGTTAC
CGGCACGCTACAGCTTATGGCAATCTGGTCAGCTATCGTCAAAAGCGTGATGGCGTTGATGAGTACGTTGAAGCATGGAG
CCGACGCGCAGAATATGACAACAAAACCGACAAAATAGAATTGTTTGGAAGCGCGCGACTGAAACGCGGCACCGATGAAG
TAGAAGGGGATTATATCTCCTACGATATAGCAAGCGACTTTTTTCAGGTATTTGGCCAGCCTCAAGCGGAAAATGATAAA
AATTCTGATCACAGGGTACGTGCCGTGATTCAGCCAAAAGCGAAACAACCTGACGCAGAAACAGAAAAATAA

Upstream 100 bases:

>100_bases
TGACGAACGTACACCACGCTCATCCCGCTAGAGGATGCCGCACCAACACGGATTCTGATTCTTCTGGTTTTCTTATTTTA
CTTTTTGTATCTATCGGTTT

Downstream 100 bases:

>100_bases
AACTATCAAAAAATATATTTACCACTGTATATCGCCACTCCGGGTCATCTTATGAGTGAATTAAGAGCTGAAAATCTGAA
AAAAAAATATCAGTCACGCA

Product: OstA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MQSQCLFLSLSLMFFSATALAERADRDKPIHLEADRATVEDYKQKGEFRTSIFTGNVILTQGTLILRADKVVMKEDSTGY
RHATAYGNLVSYRQKRDGVDEYVEAWSRRAEYDNKTDKIELFGSARLKRGTDEVEGDYISYDIASDFFQVFGQPQAENDK
NSDHRVRAVIQPKAKQPDAETEK

Sequences:

>Translated_183_residues
MQSQCLFLSLSLMFFSATALAERADRDKPIHLEADRATVEDYKQKGEFRTSIFTGNVILTQGTLILRADKVVMKEDSTGY
RHATAYGNLVSYRQKRDGVDEYVEAWSRRAEYDNKTDKIELFGSARLKRGTDEVEGDYISYDIASDFFQVFGQPQAENDK
NSDHRVRAVIQPKAKQPDAETEK
>Mature_183_residues
MQSQCLFLSLSLMFFSATALAERADRDKPIHLEADRATVEDYKQKGEFRTSIFTGNVILTQGTLILRADKVVMKEDSTGY
RHATAYGNLVSYRQKRDGVDEYVEAWSRRAEYDNKTDKIELFGSARLKRGTDEVEGDYISYDIASDFFQVFGQPQAENDK
NSDHRVRAVIQPKAKQPDAETEK

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=176, Percent_Identity=32.9545454545455, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 20889; Mature: 20889

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSQCLFLSLSLMFFSATALAERADRDKPIHLEADRATVEDYKQKGEFRTSIFTGNVILT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCEEEEEEECCEEEE
QGTLILRADKVVMKEDSTGYRHATAYGNLVSYRQKRDGVDEYVEAWSRRAEYDNKTDKIE
CCEEEEEECEEEEECCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEE
LFGSARLKRGTDEVEGDYISYDIASDFFQVFGQPQAENDKNSDHRVRAVIQPKAKQPDAE
EEECCHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCC
TEK
CCC
>Mature Secondary Structure
MQSQCLFLSLSLMFFSATALAERADRDKPIHLEADRATVEDYKQKGEFRTSIFTGNVILT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCEEEEEEECCEEEE
QGTLILRADKVVMKEDSTGYRHATAYGNLVSYRQKRDGVDEYVEAWSRRAEYDNKTDKIE
CCEEEEEECEEEEECCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEE
LFGSARLKRGTDEVEGDYISYDIASDFFQVFGQPQAENDKNSDHRVRAVIQPKAKQPDAE
EEECCHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCC
TEK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]