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The map label for this gene is rsmB [H]

Identifier: 114332240

GI number: 114332240

Start: 2406141

End: 2407415

Strand: Direct

Name: rsmB [H]

Synonym: Neut_2280

Alternate gene names: 114332240

Gene position: 2406141-2407415 (Clockwise)

Preceding gene: 114332239

Following gene: 114332244

Centisome position: 90.42

GC content: 48.08

Gene sequence:

>1275_bases
ATGCGCCTGACCCCCGAACGACTGAATCTGCTGATTATCGCCGTACGCAAGGTGTTACCTCTACAAGCCCCGGCAGATGT
GCTACTGCGACAATTTTTCCGGGATTATCCGCAGCTGGGACAAAATGGCCGGAGCATGATTGCAGAAACTGTCTTTGGAA
TCCTGAGACATCGATTTTTCCTGGAAGTACTGACCGGAAAAGCAACTGCTCGTGAACTGGTATTAGCCTATCTGGCCAGA
TTCCAAGGTATGAATCTACGGGAATTAACCCCACTCATCCGGGAGGTGGAATCCAAATGGATCCAACAAATCAAAGCGGT
AAAACTGGAGGAACAACCACAGTTCATACGGGCAGAGTTCCCGGAATGGCTGGTAGGAAAATTGCAGCAATCCTGGTCGG
ATGAAGATATTTTGCGTCTTGGCCAAGTTTTGCAACAACCCGCTCCATTGGATATACGTGTCAACAGCCTACTTGCAAAA
CGTGAAGAAGTAATTGCTGTACTGAAACAGGAAGGAATTGAAGCTCAGTCCACGCCCTTTTCTCCCGTTGGTATCCGCCT
CACTGGCAATCCAGCAATCAACCGGAACGCATTGTTCCTTTCCGGAAAAATTGAAGTGCAGGATGAAGGCAGCCAAATTC
TCGGTTTTCTGCTGGCACCCAAGCGAGGCGAGATGGTAGTAGACTTTTGTGCCGGCGCGGGAGGTAAAACATTGCTGCTC
GGCGCATTGATGCATTCTCGCGGGCGCCTGTATGCTTTTGATATTTCTGAAAAGCGGCTCAACAACCTCAAACCCAGGCT
CAAACGCTCTGGATTATCGAACGTTCACCCGCAACACATTGATAGCGAAAAAGATATCAAGCTGAAACGATTAGCGGGAA
AAATTGACCGGGTATTAGTCGATGCCCCCTGCAGCGGGCTAGGCACTTTACGCCGTAACCCTGACTTAAAGTGGCGACAA
AGTCCGGAAAGTATCAACGAGCTGCAGAAAAAACAAATAGCCATTCTTACGGCCGCCGCAAAATTGCTGAAACCGGGAGG
GCGTCTAGTTTATGCAACCTGCAGTCTGTTGCCAGAAGAGAATCAGCAGGTAATTGAACGCTTTTTAGCAGATCATCCAC
AATTTTCCATACTTAATTGTGGAGAGCTGCTTGCACAACAAAAAATCAACTTGCCTGATACAGGTGAATTTTTACAGCTC
TCGCCGTTATACCACAATACTGACGGCTTCTTTGCTGCTGTTCTGGAACACTCCAGAATGGAGCCCAAAAATTAA

Upstream 100 bases:

>100_bases
ATTTCGACAGAAAAAAGCGGGATGGAAGTAGACCAGCTAGTTACTAAAATAGACTACAAGTCTTCAGCAAGTTCCACACA
ATGACCCATTTAAACTGCTT

Downstream 100 bases:

>100_bases
AAAGGGGCCTTAGAGAAAAGGCCCCTTCAGAATGCAAGCAGCTAACTTGAGTTACTGCTTGCAGAAATTAATTATTATTG
TTATTTCAGATCATCAATAC

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MRLTPERLNLLIIAVRKVLPLQAPADVLLRQFFRDYPQLGQNGRSMIAETVFGILRHRFFLEVLTGKATARELVLAYLAR
FQGMNLRELTPLIREVESKWIQQIKAVKLEEQPQFIRAEFPEWLVGKLQQSWSDEDILRLGQVLQQPAPLDIRVNSLLAK
REEVIAVLKQEGIEAQSTPFSPVGIRLTGNPAINRNALFLSGKIEVQDEGSQILGFLLAPKRGEMVVDFCAGAGGKTLLL
GALMHSRGRLYAFDISEKRLNNLKPRLKRSGLSNVHPQHIDSEKDIKLKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWRQ
SPESINELQKKQIAILTAAAKLLKPGGRLVYATCSLLPEENQQVIERFLADHPQFSILNCGELLAQQKINLPDTGEFLQL
SPLYHNTDGFFAAVLEHSRMEPKN

Sequences:

>Translated_424_residues
MRLTPERLNLLIIAVRKVLPLQAPADVLLRQFFRDYPQLGQNGRSMIAETVFGILRHRFFLEVLTGKATARELVLAYLAR
FQGMNLRELTPLIREVESKWIQQIKAVKLEEQPQFIRAEFPEWLVGKLQQSWSDEDILRLGQVLQQPAPLDIRVNSLLAK
REEVIAVLKQEGIEAQSTPFSPVGIRLTGNPAINRNALFLSGKIEVQDEGSQILGFLLAPKRGEMVVDFCAGAGGKTLLL
GALMHSRGRLYAFDISEKRLNNLKPRLKRSGLSNVHPQHIDSEKDIKLKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWRQ
SPESINELQKKQIAILTAAAKLLKPGGRLVYATCSLLPEENQQVIERFLADHPQFSILNCGELLAQQKINLPDTGEFLQL
SPLYHNTDGFFAAVLEHSRMEPKN
>Mature_424_residues
MRLTPERLNLLIIAVRKVLPLQAPADVLLRQFFRDYPQLGQNGRSMIAETVFGILRHRFFLEVLTGKATARELVLAYLAR
FQGMNLRELTPLIREVESKWIQQIKAVKLEEQPQFIRAEFPEWLVGKLQQSWSDEDILRLGQVLQQPAPLDIRVNSLLAK
REEVIAVLKQEGIEAQSTPFSPVGIRLTGNPAINRNALFLSGKIEVQDEGSQILGFLLAPKRGEMVVDFCAGAGGKTLLL
GALMHSRGRLYAFDISEKRLNNLKPRLKRSGLSNVHPQHIDSEKDIKLKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWRQ
SPESINELQKKQIAILTAAAKLLKPGGRLVYATCSLLPEENQQVIERFLADHPQFSILNCGELLAQQKINLPDTGEFLQL
SPLYHNTDGFFAAVLEHSRMEPKN

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=316, Percent_Identity=27.2151898734177, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI76150623, Length=316, Percent_Identity=27.2151898734177, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI270288818, Length=378, Percent_Identity=27.5132275132275, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI23199998, Length=315, Percent_Identity=27.9365079365079, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI8922322, Length=315, Percent_Identity=27.9365079365079, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI270288816, Length=315, Percent_Identity=27.9365079365079, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI32698918, Length=178, Percent_Identity=33.1460674157303, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI39995082, Length=184, Percent_Identity=33.695652173913, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI301336155, Length=184, Percent_Identity=33.695652173913, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI11545785, Length=170, Percent_Identity=34.1176470588235, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI2367212, Length=413, Percent_Identity=29.0556900726392, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI87081985, Length=293, Percent_Identity=30.7167235494881, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17536757, Length=311, Percent_Identity=27.0096463022508, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25143471, Length=284, Percent_Identity=29.5774647887324, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71998419, Length=219, Percent_Identity=33.7899543378995, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115534021, Length=222, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324268, Length=307, Percent_Identity=25.4071661237785, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6319447, Length=198, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI22024126, Length=288, Percent_Identity=28.125, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI21356579, Length=231, Percent_Identity=31.6017316017316, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355201, Length=190, Percent_Identity=35.2631578947368, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19920494, Length=168, Percent_Identity=32.7380952380952, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 47756; Mature: 47756

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTPERLNLLIIAVRKVLPLQAPADVLLRQFFRDYPQLGQNGRSMIAETVFGILRHRFF
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LEVLTGKATARELVLAYLARFQGMNLRELTPLIREVESKWIQQIKAVKLEEQPQFIRAEF
HHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
PEWLVGKLQQSWSDEDILRLGQVLQQPAPLDIRVNSLLAKREEVIAVLKQEGIEAQSTPF
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
SPVGIRLTGNPAINRNALFLSGKIEVQDEGSQILGFLLAPKRGEMVVDFCAGAGGKTLLL
CCEEEEEECCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCCCEEEEEECCCCCHHHHH
GALMHSRGRLYAFDISEKRLNNLKPRLKRSGLSNVHPQHIDSEKDIKLKRLAGKIDRVLV
HHHHHCCCCEEEEECCHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEE
DAPCSGLGTLRRNPDLKWRQSPESINELQKKQIAILTAAAKLLKPGGRLVYATCSLLPEE
ECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCC
NQQVIERFLADHPQFSILNCGELLAQQKINLPDTGEFLQLSPLYHNTDGFFAAVLEHSRM
CHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCCCCCEEECCCEECCCHHHHHHHHHCCC
EPKN
CCCC
>Mature Secondary Structure
MRLTPERLNLLIIAVRKVLPLQAPADVLLRQFFRDYPQLGQNGRSMIAETVFGILRHRFF
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LEVLTGKATARELVLAYLARFQGMNLRELTPLIREVESKWIQQIKAVKLEEQPQFIRAEF
HHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
PEWLVGKLQQSWSDEDILRLGQVLQQPAPLDIRVNSLLAKREEVIAVLKQEGIEAQSTPF
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
SPVGIRLTGNPAINRNALFLSGKIEVQDEGSQILGFLLAPKRGEMVVDFCAGAGGKTLLL
CCEEEEEECCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCCCEEEEEECCCCCHHHHH
GALMHSRGRLYAFDISEKRLNNLKPRLKRSGLSNVHPQHIDSEKDIKLKRLAGKIDRVLV
HHHHHCCCCEEEEECCHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEE
DAPCSGLGTLRRNPDLKWRQSPESINELQKKQIAILTAAAKLLKPGGRLVYATCSLLPEE
ECCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCC
NQQVIERFLADHPQFSILNCGELLAQQKINLPDTGEFLQLSPLYHNTDGFFAAVLEHSRM
CHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCCCCCEEECCCEECCCHHHHHHHHHCCC
EPKN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]