Click here to switch to the map view.

The map label for this gene is insF1 [C]

Identifier: 114332228

GI number: 114332228

Start: 2390485

End: 2391804

Strand: Reverse

Name: insF1 [C]

Synonym: Neut_2268

Alternate gene names: 114332228

Gene position: 2391804-2390485 (Counterclockwise)

Preceding gene: 114332235

Following gene: 114332224

Centisome position: 89.88

GC content: 47.8

Gene sequence:

>1320_bases
GTGCGTCGAGCGATACAAAATAGTCAAGAGAGTCTGAATGTTCTGGCCAAGCGGCATGGGATTAATCCAAAAACGGTAGC
GAAGTGGCGGAAGCGGGAATTCACCCACGATGCACCGATGGGCCCCAAAGAGTCGCACTCGACTGTTTTAAGTCTGGAAG
AAGAAGCCGCTGTTGTGGCGTTTCGCAAACATACGCTTCTACCGCTGGATGATTGTCTATATGCCTTGCAACCAAGCATT
CCGCATTTAACCCGCTCAAGCCTGCATCGCTGCTTTCAACGGCATGGCATCAGTCGGTTGCCGGAGGCTGATGGTGACAA
GCCAAAGAAAAAGTTTAATGCCTATCCAATTGGCTACTTCCATATTGATATTGCCGAAGTTCGTACGAAGGAAGGTAAAC
TCTATCTTTTTGTAGCCATTGACCGGACATCAAAGTTCGTTTTTGTTCAACTCCAGAACAAAGCCAACCGCAACACGGCA
ACCGCCTTCTTGAAGGCCGTGATCGAGACTGTTCCCTACAAGATCCATACAATCCTGACTGATAACGGTATCCAGTTTAC
GTTCCCGGCGCGTTATCGGAATGGGCCAACGGCTCAGTATGTAACGCATATGTTCGATAGGTGTTGTCAGATCAACGGCA
TCGAGCACCGTCTCACCAAACCCAACCATCCCTGGACCAATGGTCAGGTTGAACGCATGAATCGAACCATCAAGGATGCG
ACTGTAAAACGGTATTATTACGACTCACACGATCAGTTGAAGGCCCATCTCCATCGCTTTGTGATGGCTTATAACTTCGC
CAAAAGACTAAAAGCTCTCAAAGGCCTAACACCCTATGAATACATCTGCAAAATCTGGAAAAATGAGCCAGATCGTTTTA
TCTTTGATCCATTCCAGCACACCGTGGGACTAAACAATTTCTCTCCCAAACAGCCTAACCTGGTGTGGACAACCGACATC
ACTTACATCTGGACAGCACAAGGATGGGTATATTTAGCGGTTGTACTGGATCTCTACTCACGGCGCATTGTGGGTTGGCA
TATGGAGTATTACATGACGACTGCTCTGGTAAATCGTGCACTGATGATGGCAATCAACCTGAGACAACCACCAAAAAATC
TGTTGCATCACTCCGACAGAGGTAGCCAGTATGCTTCACACGACTACCAAACGCTACTGACTCAGCACAACATGCAATGT
TCGATAAGCCGCAAAGGAAACTGTTGGGATACTCAGTTCGTGCCTGACGTACGTCTGTGCGCGATTGCTCGCTGGCGTGC
AGGGTTTTTTTTAAAACTCAACCCCCATTTGTTCAGTTGA

Upstream 100 bases:

>100_bases
ATTGTTTAGTCCCACGGTGTGCCGGTGTAACATATAACCAGCTACGGAGGGATGATTTATGGGACAGATATTACACGGAA
GCGCCCGCACGACAGTGGCG

Downstream 100 bases:

>100_bases
TGCCATAGCGCCGGCACCTTGATCTGAATGCCTTCTGCAGCCAAACGTTCACTGAGCTCGACAAGCGTTAGATCCGGCGT
GGCTTCTATCCATTGCCGAA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MRRAIQNSQESLNVLAKRHGINPKTVAKWRKREFTHDAPMGPKESHSTVLSLEEEAAVVAFRKHTLLPLDDCLYALQPSI
PHLTRSSLHRCFQRHGISRLPEADGDKPKKKFNAYPIGYFHIDIAEVRTKEGKLYLFVAIDRTSKFVFVQLQNKANRNTA
TAFLKAVIETVPYKIHTILTDNGIQFTFPARYRNGPTAQYVTHMFDRCCQINGIEHRLTKPNHPWTNGQVERMNRTIKDA
TVKRYYYDSHDQLKAHLHRFVMAYNFAKRLKALKGLTPYEYICKIWKNEPDRFIFDPFQHTVGLNNFSPKQPNLVWTTDI
TYIWTAQGWVYLAVVLDLYSRRIVGWHMEYYMTTALVNRALMMAINLRQPPKNLLHHSDRGSQYASHDYQTLLTQHNMQC
SISRKGNCWDTQFVPDVRLCAIARWRAGFFLKLNPHLFS

Sequences:

>Translated_439_residues
MRRAIQNSQESLNVLAKRHGINPKTVAKWRKREFTHDAPMGPKESHSTVLSLEEEAAVVAFRKHTLLPLDDCLYALQPSI
PHLTRSSLHRCFQRHGISRLPEADGDKPKKKFNAYPIGYFHIDIAEVRTKEGKLYLFVAIDRTSKFVFVQLQNKANRNTA
TAFLKAVIETVPYKIHTILTDNGIQFTFPARYRNGPTAQYVTHMFDRCCQINGIEHRLTKPNHPWTNGQVERMNRTIKDA
TVKRYYYDSHDQLKAHLHRFVMAYNFAKRLKALKGLTPYEYICKIWKNEPDRFIFDPFQHTVGLNNFSPKQPNLVWTTDI
TYIWTAQGWVYLAVVLDLYSRRIVGWHMEYYMTTALVNRALMMAINLRQPPKNLLHHSDRGSQYASHDYQTLLTQHNMQC
SISRKGNCWDTQFVPDVRLCAIARWRAGFFLKLNPHLFS
>Mature_439_residues
MRRAIQNSQESLNVLAKRHGINPKTVAKWRKREFTHDAPMGPKESHSTVLSLEEEAAVVAFRKHTLLPLDDCLYALQPSI
PHLTRSSLHRCFQRHGISRLPEADGDKPKKKFNAYPIGYFHIDIAEVRTKEGKLYLFVAIDRTSKFVFVQLQNKANRNTA
TAFLKAVIETVPYKIHTILTDNGIQFTFPARYRNGPTAQYVTHMFDRCCQINGIEHRLTKPNHPWTNGQVERMNRTIKDA
TVKRYYYDSHDQLKAHLHRFVMAYNFAKRLKALKGLTPYEYICKIWKNEPDRFIFDPFQHTVGLNNFSPKQPNLVWTTDI
TYIWTAQGWVYLAVVLDLYSRRIVGWHMEYYMTTALVNRALMMAINLRQPPKNLLHHSDRGSQYASHDYQTLLTQHNMQC
SISRKGNCWDTQFVPDVRLCAIARWRAGFFLKLNPHLFS

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=112, Percent_Identity=43.75, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1788405, Length=118, Percent_Identity=45.7627118644068, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787263, Length=118, Percent_Identity=45.7627118644068, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786753, Length=118, Percent_Identity=45.7627118644068, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786570, Length=118, Percent_Identity=45.7627118644068, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786490, Length=118, Percent_Identity=45.7627118644068, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1789981, Length=109, Percent_Identity=32.1100917431193, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 51279; Mature: 51279

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAIQNSQESLNVLAKRHGINPKTVAKWRKREFTHDAPMGPKESHSTVLSLEEEAAVVA
CCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHEEE
FRKHTLLPLDDCLYALQPSIPHLTRSSLHRCFQRHGISRLPEADGDKPKKKFNAYPIGYF
ECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCEEEE
HIDIAEVRTKEGKLYLFVAIDRTSKFVFVQLQNKANRNTATAFLKAVIETVPYKIHTILT
EEEHHHHCCCCCCEEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEE
DNGIQFTFPARYRNGPTAQYVTHMFDRCCQINGIEHRLTKPNHPWTNGQVERMNRTIKDA
CCCEEEEECHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHH
TVKRYYYDSHDQLKAHLHRFVMAYNFAKRLKALKGLTPYEYICKIWKNEPDRFIFDPFQH
HHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCHHH
TVGLNNFSPKQPNLVWTTDITYIWTAQGWVYLAVVLDLYSRRIVGWHMEYYMTTALVNRA
HCCCCCCCCCCCCEEEEECEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMMAINLRQPPKNLLHHSDRGSQYASHDYQTLLTQHNMQCSISRKGNCWDTQFVPDVRLC
HHHHEECCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHH
AIARWRAGFFLKLNPHLFS
HHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MRRAIQNSQESLNVLAKRHGINPKTVAKWRKREFTHDAPMGPKESHSTVLSLEEEAAVVA
CCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCHHHEEE
FRKHTLLPLDDCLYALQPSIPHLTRSSLHRCFQRHGISRLPEADGDKPKKKFNAYPIGYF
ECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCEEEE
HIDIAEVRTKEGKLYLFVAIDRTSKFVFVQLQNKANRNTATAFLKAVIETVPYKIHTILT
EEEHHHHCCCCCCEEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEE
DNGIQFTFPARYRNGPTAQYVTHMFDRCCQINGIEHRLTKPNHPWTNGQVERMNRTIKDA
CCCEEEEECHHCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHH
TVKRYYYDSHDQLKAHLHRFVMAYNFAKRLKALKGLTPYEYICKIWKNEPDRFIFDPFQH
HHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEECCHHH
TVGLNNFSPKQPNLVWTTDITYIWTAQGWVYLAVVLDLYSRRIVGWHMEYYMTTALVNRA
HCCCCCCCCCCCCEEEEECEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMMAINLRQPPKNLLHHSDRGSQYASHDYQTLLTQHNMQCSISRKGNCWDTQFVPDVRLC
HHHHEECCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHH
AIARWRAGFFLKLNPHLFS
HHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]